75,305 research outputs found
Preferential duplication graphs
We consider a preferential duplication model for growing random graphs, extending previous models of duplication graphs by selecting the vertex to be duplicated with probability proportional to its degree. We show that a special case of this model can be analysed using the same stochastic approximation as for vertex-reinforced random walks, and show that 'trapping' behaviour can occur, such that the descendants of a particular group of initial vertices come to dominate the graph
From the Kubo formula to variable range hopping
Consider a multichannel closed ring with disorder. In the semiclassical
treatment its conductance is given by the Drude formula. Quantum mechanics
challenge this result both in the limit of strong disorder (eigenstates are not
quantum-ergodic in real space) and in the limit of weak disorder (eigenstates
are not quantum-ergodic in momentum space). Consequently the analysis of
conductance requires going beyond linear response theory, leading to a resistor
network picture of transitions between energy levels. We demonstrate that our
semi-linear response theory provides a firm unified framework from which the
"hopping" phenomenology of Mott can be derived.Comment: 5 pages, published version with an extended concluding paragrap
Electroweak baryogenesis from chargino transport in the supersymmetric model
We study the baryon asymmetry of the universe in the supersymmetric standard
model (SSM). At the electroweak phase transition, the fermionic partners of the
charged SU(2) gauge bosons and Higgs bosons are reflected from or transmitted
to the bubble wallof the broken phase. Owing to a physical complex phase in
their mass matrix, these reflections and transmissions have asymmetries between
CP conjugate processes. Equilibrium conditions in the symmetric phaseare then
shifted to favor a non-vanishing value for the baryon number density, which is
realized through electroweak anomaly. We show that the resultant ratio of
baryon number to entropy is consistent with its present observed value within
reasonable ranges of SSM parameters, provided that the CP-violating phase
intrinsic in the SSM is not much suppressed. The compatibility with the
constraints on the parameters from the electric dipole moment of the neutron is
also discussed.Comment: 23 page
The volume in focus: hardwareassisted focus and context effects for volume visualization
In many volume visualization applications there is some region of specific interest where we wish to see fine detail - yet we do not want to lose an impression of the overall picture. In this research we apply the notion of focus and context to texture-based volume rendering. A framework has been developed that enables users to achieve fast volumetric distortion and other effects of practical use. The framework has been implemented through direct programming of the graphics processor and integrated into a volume rendering system. Our driving application is the effective visualization of aneurysms, an important issue in neurosurgery. We have developed and evaluated an easy-to-use system that allows a neurosurgicalteam to explore the nature of cerebral aneurysms, visualizing the aneurysm itself in fine detail while still retaining a view of the
surrounding vasculature
Crinoid phylogeny: a preliminary analysis (Echinodermata: Crinoidea)
We describe the first molecular and morphological analysis of extant crinoid high-level inter-relationships. Nuclear and mitochondrial gene sequences and a cladistically coded matrix of 30 morphological characters are presented, and analysed by phylogenetic methods. The molecular data were compiled from concatenated nuclear-encoded 18S rDNA, internal transcribed spacer 1, 5.8S rDNA, and internal transcribed spacer 2, together with part of mitochondrial 16S rDNA, and comprised 3,593 sites, of which 313 were parsimony-informative. The molecular and morphological analyses include data from the bourgueticrinid Bathycrinus; the antedonid comatulids Dorometra and Florometra; the cyrtocrinids Cyathidium, Gymnocrinus, and Holopus; the isocrinids Endoxocrinus, and two species of Metacrinus; as well as from Guillecrinus and Caledonicrinus, whose ordinal relationships are uncertain, together with morphological data from Proisocrinus. Because the molecular data include indel-rich regions, special attention was given to alignment procedure, and it was found that relatively low, gene-specific, gap penalties gave alignments from which congruent phylogenetic information was obtained from both well-aligned, indel-poor and potentially misaligned, indel-rich regions. The different sequence data partitions also gave essentially congruent results. The overall direction of evolution in the gene trees remains uncertain: an asteroid outgroup places the root on the branch adjacent to the slowly evolving isocrinids (consistent with palaeontological order of first appearances), but maximum likelihood analysis with a molecular clock places it elsewhere. Despite lineage-specific rate differences, the clock model was not excluded by a likelihood ratio test. Morphological analyses were unrooted. All analyses identified three clades, two of them generally well-supported. One well-supported clade (BCG) unites Bathycrinus and Guillecrinus with the representative (chimaeric) comatulid in a derived position, suggesting that comatulids originated from a sessile, stalked ancestor. In this connection it is noted that because the comatulid centrodorsal ossicle originates ontogenetically from the column, it is not strictly correct to describe comatulids as unstalked crinoids. A second, uniformly well-supported clade contains members of the Isocrinida, while the third clade contains Gymnocrinus, a well-established member of the Cyrtocrinida, together with the problematic taxon Caledonicrinus, currently classified as a bourgueticrinid. Another cyrtocrinid, Holopus, joins this clade with only weak molecular, but strong morphological support. In one morphological analysis Proisocrinus is weakly attached to the isocrinid clade. Only an unusual, divergent 18S rDNA sequence was obtained from the morphologically strange cyrtocrinid Cyathidium. Although not analysed in detail, features of this sequence suggested that it may be a PCR artefact, so that the apparently basal position of this taxon requires confirmation. If not an artefact, Cyathidium either diverged from the crinoid stem much earlier than has been recognised hitherto (i.e., it may be a Palaeozoic relic), or it has an atypically high rate of molecular evolution
Regions of beta 2 and beta 4 responsible for differences between the steady state dose-response relationships of the alpha 3 beta 2 and alpha 3 beta 4 neuronal nicotinic receptors
We constructed chimeras of the rat beta 2 and beta 4 neuronal nicotinic subunits to locate the regions that contribute to differences between the acetylcholine (ACh) dose-response relationships of the alpha 3 beta 2 and alpha 3 beta 4 receptors. Expressed in Xenopus oocytes, the alpha 3 beta 2 receptor displays an EC50 for ACh approximately 20-fold less than the EC50 of the alpha 3 beta 4 receptor. The apparent Hill slope (n(app)) of alpha 3 beta 2 is near one whereas the alpha 3 beta 4 receptor displays an n(app) near two. Substitutions within the first 120 residues convert the EC50 for ACh from one wild-type value to the other. Exchanging just beta 2:104-120 for the corresponding region of beta 4 shifts the EC50 of ACh dose-response relationship in the expected direction but does not completely convert the EC50 of the dose- response relationship from one wild-type value to the other. However, substitutions in the beta 2:104-120 region do account for the relative sensitivity of the alpha 3 beta 2 receptor to cytisine, tetramethylammonium, and ACh. The expression of beta 4-like (strong) cooperativity requires an extensive region of beta 4 (beta 4:1-301). Relatively short beta 2 substitutions (beta 2:104-120) can reduce cooperativity to beta 2-like values. The results suggest that amino acids within the first 120 residues of beta 2 and the corresponding region of beta 4 contribute to an agonist binding site that bridges the alpha and beta subunits in neuronal nicotinic receptors
Life and death of a hero - Lessons learned from modeling the dwarf spheroidal Hercules: an incorrect orbit?
Hercules is a dwarf spheroidal satellite of the Milky Way, found at a
distance of about 138 kpc, and showing evidence of tidal disruption. It is very
elongated and exhibits a velocity gradient of 16 +/- 3 km/s/kpc. Using this
data a possible orbit of Hercules has previously been deduced in the
literature. In this study we make use of a novel approach to find a best fit
model that follows the published orbit. Instead of using trial and error, we
use a systematic approach in order to find a model that fits multiple
observables simultaneously. As such, we investigate a much wider parameter
range of initial conditions and ensure we have found the best match possible.
Using a dark matter free progenitor that undergoes tidal disruption, our
best-fit model can simultaneously match the observed luminosity, central
surface brightness, effective radius, velocity dispersion, and velocity
gradient of Hercules. However, we find it is impossible to reproduce the
observed elongation and the position angle of Hercules at the same time in our
models. This failure persists even when we vary the duration of the simulation
significantly, and consider a more cuspy density distribution for the
progenitor. We discuss how this suggests that the published orbit of Hercules
is very likely to be incorrect.Comment: accepted by MNRAS; 19 pages, 19 figures, 2 table
Harmonic oscillators coupled by springs: discrete solutions as a Wigner Quantum System
We consider a quantum system consisting of a one-dimensional chain of M
identical harmonic oscillators with natural frequency , coupled by
means of springs. Such systems have been studied before, and appear in various
models. In this paper, we approach the system as a Wigner Quantum System, not
imposing the canonical commutation relations, but using instead weaker
relations following from the compatibility of Hamilton's equations and the
Heisenberg equations. In such a setting, the quantum system allows solutions in
a finite-dimensional Hilbert space, with a discrete spectrum for all physical
operators. We show that a class of solutions can be obtained using generators
of the Lie superalgebra gl(1|M). Then we study the properties and spectra of
the physical operators in a class of unitary representations of gl(1|M). These
properties are both interesting and intriguing. In particular, we can give a
complete analysis of the eigenvalues of the Hamiltonian and of the position and
momentum operators (including multiplicities). We also study probability
distributions of position operators when the quantum system is in a stationary
state, and the effect of the position of one oscillator on the positions of the
remaining oscillators in the chain
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