DNS of Laminar to Turbulent Transition on NACA 0012 Airfoil with Sand Grain Roughness

The Lattice-Boltzmann-based solver PowerFLOW is used to perform direct numerical simulations of the transitional flow over an airfoil at Reynolds number equal to 0.657 million. The leading edge of the airfoil is covered with sand particles, represented by polyhedra, to mimic the grit used in experiments. The sensitivity of the laminar to turbulent transition to the size of these particles, grid resolution, spanwise length is evaluated and rectangular trips are also tested

Topological Defects in the Left-Right Symmetric Model and their Relevance to Cosmology

It is shown that the minimal left-right symmetric model admits cosmic string and domain wall solutions. The cosmic strings arise when the SU(2)_R is broken and can either be destabilized at the electroweak scale or remain stable through the subsequent breakdown to U(1)_{EM}. The strings carry zero modes of the neutrino fields. Two distinct domain wall configurations exist above the electroweak phase transition and disappear after that. Thier destablization provides new sources of non-equilibrium effects below the electroweak scale which is relevant to baryogenesis.Comment: 29 pages, LaTex file with 6 postscript figure

Multiple scales approach to weakly nonparallel and curvature effects: Details for the novice

A multiple scales approach is used to approximate the effects of nonparallelism and streamwise curvature on the stability of three-dimensional disturbances in incompressible flow. The multiple scales approach is implemented with the full second-order system of equations. A detailed exposition of the source of all terms is provided

Chronic maxillary osteomyelitis secondary to chronic maxillary sinusitis in non-immunocompromised patient – a rare case report and its management

Osteomyelitis is an inflammation of medullary portion of bone along with cortex and periosteum. It is one of most difficult infectious diseases to treat. Facial bones are prone to osteomyelitis due to various predisposing condition. Osteomyelitis of maxilla is rare disease and less frequently encountered. Objective: The aim of the article is to present an unusual case of chronic maxillary osteomyelitis secondary to rhinogenic which are rarely clinically causes. Case report: We hereby report a case of chronic maxillary osteomyelitis in 70-year-old non-immunocompromised patient secondary to chronic maxillary sinusitis. Complete resolution of chronic maxillary osteomyelitis was achieved by combination of antimicrobial therapy and surgical treatment. Conclusion: Clinician should identify such risk and provide the aggressive treatment modalities to avoid subsequent dreaded consequences.Osteomyelitis is an inflammation of medullary portion of bone along with cortex and periosteum. It is one of most difficult infectious diseases to treat. Facial bones are prone to osteomyelitis due to various predisposing condition. Osteomyelitis of maxilla is rare disease and less frequently encountered. Objective: The aim of the article is to present an unusual case of chronic maxillary osteomyelitis secondary to rhinogenic which are rarely clinically causes. Case report: We hereby report a case of chronic maxillary osteomyelitis in 70-year-old non-immunocompromised patient secondary to chronic maxillary sinusitis. Complete resolution of chronic maxillary osteomyelitis was achieved by combination of antimicrobial therapy and surgical treatment. Conclusion: Clinician should identify such risk and provide the aggressive treatment modalities to avoid subsequent dreaded consequences

Facial herpes zoster infection precipitated by surgical manipulation of the trigeminal nerve during exploration of the posterior fossa: a case report

<p>Abstract</p> <p>Introduction</p> <p>We present a case of herpes zoster infection (shingles) precipitated by surgical manipulation of the trigeminal nerve root during an attempted microvascular decompression procedure. The pathogenesis of this phenomenon, as well as the importance and role of prophylactic acyclovir in its management, are discussed.</p> <p>Case presentation</p> <p>A 54-year-old Caucasian man with a classical long-standing left-sided V2 and V3 division primary trigeminal neuralgia refractory to medical management, underwent posterior fossa exploration for microvascular decompression via a standard retromastoid craniectomy. The patient had immediate and complete relief from pain. Three days after the operation, he developed severely painful vesicles with V2 and V3 dermatomal distribution. Rather than the classical paroxysmal, lancinating type of trigeminal neuralgia, the pain experienced by the patient was of a constant burning nature. A clinical diagnosis of herpes zoster (shingles) was made after smear confirmation from microbiological testing. The patient was commenced on antiviral treatment with acyclovir. His vesicular rash and pain gradually subsided over the next two weeks. He remains asymptomatic one year later.</p> <p>Conclusions</p> <p>Postoperative shingles precipitated by trigeminal nerve manipulation during surgery for trigeminal neuralgia can be a distressing and demoralizing experience for the patient. A careful preoperative history, early recognition, and prompt antiviral therapy is necessary.</p

An interesting case report of ruptured pyogenic liver abscess with 40 weeks gestation in labour

Pyogenic liver abscess during pregnancy is an extremely rare condition. Although rare, in situations of sepsis or septic shock in pregnancy, as well as the common sources of infection, a possibility of a liver abscess should be considered. We present a case report of 32-year-old primigravida 37.3 weeks by date, 37 weeks by scan with breech presentation with premature rupture of membranes and pain in abdomen since 12 hours with breathlessness, fever and diarrhoea since 2 days came in emergency to study hospital. General condition of the patient on arrival was pulse-140 beats per minute, blood pressure was 90/60 mmHg, respiratory rate was 40/min, on per abdominal examination, breech presentation with fetal heart rate of 150 beats per minute on doppler was noted. Per vaginal examination revealed cervical os 5 cm dilated, 40% effacement, breech presentation, absent membranes. With urgent report of complete hemogram and acid blood gas analysis, metabolic acidosis was noted which was corrected and patient was taken for emergency lower segment caesarean section. Intra-operative, 250 ml greenish pus flakes fluid was noted inside the abdominal cavity. Fluid was drained and sent for culture sensitivity with maximum aseptic precautions, uterus was opened, baby was delivered followed by uterus closure. Ruptured liver abscess 6×4×2 cm in 2nd and 3rd segment of liver was noted, abdominal wash with antibiotics and NS was given, drain was kept. Appropriate antibiotics were started and was discharged on day 14 after suture removal

Antibiotic profiling of Pseudomonas aeruginosa isolates from pus sample of rural tertiary care hospital of Western Maharashtra, Loni, India

Background: Pseudomonas aeruginosa (P. aeruginosa) considered as an opportunistic pathogen which can be isolated from various kinds of infection. The risk of emergence of antibiotic resistance is based on different antibiotic treatments. Antibiotic resistance and flexibility to adapt changing environment renders the pathogens a matter of concern in hospital acquired infections. Changing pattern of antimicrobial resistance pose challenge in treating pyogenic infections, hence periodical monitoring of bacterial profile and their antibiotic susceptibility pattern is important. This study deals with the infectious and drug resistance nature of P. aeruginosa with effectiveness of antimicrobial agents against it.Methods: Present study was conducted in Centre for Biotechnology, Pravara Institute of Medical Sciences, Loni, Maharashtra, India. A total of 763 pus samples were received in the bacteriology section of department of microbiology, rural medical college, Loni from the various wards of Pravara Rural Hospital. The colonial morphology and identification was done as per standard microbiology procedures. Antibiogram testing was done as per Kirby Bauer disc diffusion method.Results: Out of 763 pus samples 154 were Pseudomonas aeruginosa thus showing 20.19% prevalence. In this study, it was observed that isolates were sensitive to Ciprofloxacin (76.63%) followed by Amikacin. However, showed 90.90 % resistant to Cefazolin followed by Co-trimoxazole 75.97% was observed. Multi drug resistance (MDR) strain 68.83% (N=106) was detected from 154 isolates strains of Pseudomonas aeruginosa. Prevalent resistance pattern was found to be GENr, AKr, CAZr, CZr, COTr for 10 (9.43%) isolates followed by GENr, CAZr, CZr, MRPr, COTr, CIPr for 9 (8.49%) isolates.Conclusions: Present study focused on antibiotic resistance pattern of P. aeruginosa from pus sample. This study contributes in understanding the emergence of MDR strains which can be considered for judicial usage of antibiotics in hospital settings.

IR Signal Spectrum Analysis of Liquid Sample using Fast Fourier Transform Technique

The prime intention of this research work has been to study electronics sensor for the detection of infection which are widely occur in food material. So electronic sensor system is designed in which IR signal was transmitted through the sample for the detection of infection. It was noted that there was changes occurs in all the performance parameters as sample kept for number of days by maintaining the same atmospheric condition. At different range of frequency, the amplitude of received IR signal was used to plot FFT and PSD response. Fourier transform of infrared signal is used to interpret interactions between sample and electromagnetic fields in the IR region. Therefore signal spectrum of IR signal using Fourier transform is a very powerful technique which provides information on the chemical composition of the sample

Good Laboratory Practices (GLP) in an Academic Institute for Science

This article offers a comprehensive and in-depth guide to the implementation of Good Laboratory Practices (GLP) in academic institutions, emphasizing its critical role in ensuring the quality and safety of scientific research. It provides a detailed overview of the key principles and benefits of GLP while elaborating on the specific responsibilities and roles of various laboratory personnel, spanning from administrators to students. Furthermore, the article furnishes clear and actionable directives for the enhancement of overall laboratory safety measures. It serves as a valuable resource for institutions seeking to foster a culture of excellence and responsibility in their scientific endeavors