Guest Editors’ Introduction

The Pacific Asia Conference on Information Systems (PACIS), sponsored by the Association for Information Systems (AIS), is the premier annual information systems conference in the region. It aims to provide a high quality forum for researchers and practitioners to exchange research findings and practices on key issues in information systems and management. PACIS 2010 was held in Taipei, Taiwan in July 2010 and its theme is “Service Science in Information Systems Research.” In response to the transition of the global economy from the manufacturing to service-dominated economy, service science is emerging as a new and exciting paradigm. It represents a melding of information technology with an understanding of business processes and human behaviors for improving service operations, delivery, innovation, and ultimate values to customers. At the emerging stage of service science, it is essential for information systems (IS) researchers and practitioners to help shape what service science is by fusing IS research into inquiries of service science. Meanwhile, the service-centric view of servicescience may open up exciting opportunities and unique challenges to IS research. Hence, PACIS 2010 aims to facilitate the dialogues among IS professionals in academic and industries to exchange insights on issues related to service science in IS research as well as IS research to service science

The causal effect of subscription video streaming on DVD sales: Evidence from a natural experiment

Subscription-based video streaming has recently become the main revenue driver in the home entertainment industry. Whether and how it affects the sales of physical media, which was previously the industry\u27s largest revenue source for decades, is still not well understood. We answer this question using a natural experiment that occurred on October 1, 2015, when the content owner Epix switched its streaming partner from Netflix to Hulu. This event created an exogenous shock that significantly reduced the streaming availability of Epix\u27s content because of the difference in the market shares of the two streaming service providers at the time. This occurrence allows us to investigate the causal effect of subscription streaming on physical DVD sales. Our difference-in-differences analysis shows that the decline in the streaming availability of Epix\u27s content caused an increase of 36.07% in its monthly DVD sales during the 15 months after the event. We also find that the cannibalization between these two channels is much stronger for movies with higher level of content stickiness (e.g., more recent titles, and titles with a general audience (G) or parental guidance (PG) rating or belonging to the children/family genre). Our findings provide important implications for content owners on how to balance physical sales with revenues from streaming licenses

Surgical oocyte retrieval and the developmental potential of the oocytes derived from prepubertal calves

The objectives of this study were to investigate the ovarian responsiveness of juvenile calves to exogenous gonadotropin treatments and to establish the oocyte retrieval technique for prepubertal heifers. Three 78-day-old calves were treated with 4 doses (40, 30, 30 and 30 mg) of FSH (Folltropin V) at 12 h interval up to 229 day-old. Surgical oocyte retrieval was performed 24 h after the last injection of FSH. Calves with good ovarian responses to FSH treatment had an average ovarian size of 5x3 cm compared to 3x2 cm in the less-responsive animals. Large variations were observed in the number of total follicles (51 45), aspirated follicles (39 +/- 36), oocytes recovered (23 +/- 25) and usable oocytes recovered (11 +/- 19) during 78 to 229 day-old. Oocytes derived from prepubertal calves had significantly lower maturation rate than those from cows (34 vs. 100%, p<0.05). Mean diameters of calf oocytes (144 +/- 1 &mu;m) and ooplasm (110 +/- 1 &mu;m) were significantly lower than those of cows (149 +/- 1 and 125 +/- 1 &mu;m, respectively). The diameter of the ooplasm also increased significantly after in vitro maturation (IVM) (108 +/- 1 vs. 112 +/- 1 &mu;m). However, further studies are required to optimize the IVP system for the oocytes derived from prepubertal heifers

Communist Revolution and Peasant Mobilisation in the Hinterland of North China: The Early Years

This chapter examines the depiction by populism in the domain of 'popular culture' of what purports to be its non-capitalist/non-socialist alternative: in short, the socio-economic and political structure of its 'imaginary' as this involves a symptomatic opposition between the utopic and dystopic. Using the pseudonym of Ivan Kremnev, the Russian neo-populist theoretician A. V. Chayanov wrote the utopian fiction The Journey of My Brother Alexei to the Land of Peasant Utopia. Accordingly, the utopic vision of Chayanov entails traversing time but not space; the protagonists in his narrative are projected forward into a future within the same demarcated space. Much of the populist discourse which structures the agrarian myth is present in the films of Frank Capra, who directed not only Lost Horizon but also Mr Deeds Goes to Town (1936), Mr Smith Goes to Washington (1939) and t's a Wonderful Life (1946)

Impact of Postgrafting Immunosuppressive Regimens on Nonrelapse Mortality and Survival after Nonmyeloablative Allogeneic Hematopoietic Stem Cell Transplant Using the Fludarabine and Low-Dose Total-Body Irradiation 200-cGy

10.1016/j.bbmt.2007.03.002Biology of Blood and Marrow Transplantation137790-80

Anticoagulant selection in relation to the SAMe-TT2R2 score in patients with atrial fibrillation: The GLORIA-AF registry

Aim: The SAMe-TT2R2 score helps identify patients with atrial fibrillation (AF) likely to have poor anticoagulation control during anticoagulation with vitamin K antagonists (VKA) and those with scores &gt;2 might be better managed with a target-specific oral anticoagulant (NOAC). We hypothesized that in clinical practice, VKAs may be prescribed less frequently to patients with AF and SAMe-TT2R2 scores &gt;2 than to patients with lower scores. Methods and results: We analyzed the Phase III dataset of the Global Registry on Long-Term Oral Antithrombotic Treatment in Patients with Atrial Fibrillation (GLORIA-AF), a large, global, prospective global registry of patients with newly diagnosed AF and ≥1 stroke risk factor. We compared baseline clinical characteristics and antithrombotic prescriptions to determine the probability of the VKA prescription among anticoagulated patients with the baseline SAMe-TT2R2 score &gt;2 and ≤ 2. Among 17,465 anticoagulated patients with AF, 4,828 (27.6%) patients were prescribed VKA and 12,637 (72.4%) patients an NOAC: 11,884 (68.0%) patients had SAMe-TT2R2 scores 0-2 and 5,581 (32.0%) patients had scores &gt;2. The proportion of patients prescribed VKA was 28.0% among patients with SAMe-TT2R2 scores &gt;2 and 27.5% in those with scores ≤2. Conclusions: The lack of a clear association between the SAMe-TT2R2 score and anticoagulant selection may be attributed to the relative efficacy and safety profiles between NOACs and VKAs as well as to the absence of trial evidence that an SAMe-TT2R2-guided strategy for the selection of the type of anticoagulation in NVAF patients has an impact on clinical outcomes of efficacy and safety. The latter hypothesis is currently being tested in a randomized controlled trial. Clinical trial registration: URL: https://www.clinicaltrials.gov//Unique identifier: NCT01937377, NCT01468701, and NCT01671007. © 2020 Hellenic Society of Cardiolog