1,544 research outputs found
Race and native speakers in ELT: parents' perspectives in Hong Kong
English is used as an important means of international and intercultural communication around the world more than ever. Because of its widespread use in the global context, non-native speakers of English around the world outnumber native speakers by far (Crystal, 1997). According to Kachru and Nelson (1996: 79), ‘accepting even cautious estimates, there must be at least three nonnative users of English for every old-country native user’. A similar phenomenon is also observable in the English Language Teaching (ELT) profession, with the vast majority of teachers of English as a second and foreign language in the world being non-native speakers.published_or_final_versio
Thomas Jefferson Health System Medical Legal Partnership
Introduction: Medical-legal partnerships (MLPs) provide civil legal services in concert with healthcare services to mitigate complex social conditions with health-harming effects. Currently, there are 333 MLPs in 46 states. Thomas Jefferson Health System (TJHS) does not have a systemwide MLP. (Magee Rehabilitation Hospital does have an MLP used by qualifying Magee patients). This project sought to identify the core components of an MLP and to demonstrate the value an MLP would provide TJHS.
Methods: Assessed existing literature. Interviewed an existing MLP director. Patients from the Jefferson Hospital Ambulatory Practice (JHAP) clinic completed a written survey regarding health-harming social-legal issues. Entered survey data into Excel and analyzed using descriptive statistics.
Results: Six common core components of all MLPs were identified. Existing MLPs have demonstrated a reduction in readmission rates, decreased inpatient and emergency department visits, and recovery of payments for unreimbursed clinical services. Patients report improved health when unmet civil legal needs are addressed. Results of the JHAP clinic survey are pending, but preliminarily many patients appear to have social-legal issues.
Conclusions: This project demonstrates that a TJHS MLP program could improve patient health and reduce overutilization of the health system. Over time the cost of the program would potentially be offset by the recovery of healthcare dollars. TJHS patients appear to have social-legal issues that negatively impact their health and could be addressed through legal remedies. Based on the analysis, an Opportunity Assessment was generated. Critical next steps are to draft a business plan and identify potential funding
A multi-national comparison of antipsychotic drug use in children and adolescents, 2005-2012
Over the last decades, an increase in antipsychotic (AP) prescribing and a shift from first-generation antipsychotics (FGA) to second-generation antipsychotics (SGA) among youth have been reported. However, most AP prescriptions for youth are off-label, and there are worrying long-term safety data in youth. The objective of this study was to assess multinational trends in AP use among children and adolescents. A repeated cross-sectional design was applied to cohorts from varied sources from Denmark, Germany, the Netherlands, the United Kingdom (UK) and the United States (US) for calendar years 2005/2006–2012. The annual prevalence of AP use was assessed, stratified by age group, sex and subclass (FGA/SGA). The prevalence of AP use increased from 0.78 to 1.03% in the Netherlands’ data, from 0.26 to 0.48% in the Danish cohort, from 0.23 to 0.32% in the German cohort, and from 0.1 to 0.14% in the UK cohort. In the US cohort, AP use decreased from 0.94 to 0.79%. In the US cohort, nearly all ATP dispensings were for SGA, while among the European cohorts the proportion of SGA dispensings grew to nearly 75% of all AP dispensings. With the exception of the Netherlands, AP use prevalence was highest in 15–19 year-olds. So, from 2005/6 to 2012, AP use prevalence increased in all youth cohorts from European countries and decreased in the US cohort. SGA were favoured in all countries’ cohorts
Artificially lit surface of Earth at night increasing in radiance and extent
This is the author accepted manuscript. The final version is available from AAAS via the DOI in this record.A central aim of the “lighting revolution” (the transition to solid-state lighting technology) is decreased energy consumption. This could be undermined by a rebound effect of increased use in response to lowered cost of light. We use the first-ever calibrated satellite radiometer designed for night lights to show that from 2012 to 2016, Earth’s artificially lit outdoor area grew by 2.2% per year, with a total radiance growth of 1.8% per year. Continuously lit areas brightened at a rate of 2.2% per year. Large differences in national growth rates were observed, with lighting remaining stable or decreasing in only a few countries. These data are not consistent with global scale energy reductions but rather indicate increased light pollution, with corresponding negative consequences for flora, fauna, and human well-being.This article is based upon work from COST Action ES1204 LoNNe, supported by COST (European Cooperation in Science and Technology). The authors acknowledge the funding received by ERA-PLANET
(www.era-planet.eu) funded by the EC as part of H2020 (contract no. 689443). NOAA’s participation
was funded by NASA’s VIIRS science program, contract number NNH15AZ01I. ASM’s
contribution was funded by ORISON project (H2020-INFRASUPP-2015-2) Cities at Night
Quantifying Privacy: A Novel Entropy-Based Measure of Disclosure Risk
It is well recognised that data mining and statistical analysis pose a
serious treat to privacy. This is true for financial, medical, criminal and
marketing research. Numerous techniques have been proposed to protect privacy,
including restriction and data modification. Recently proposed privacy models
such as differential privacy and k-anonymity received a lot of attention and
for the latter there are now several improvements of the original scheme, each
removing some security shortcomings of the previous one. However, the challenge
lies in evaluating and comparing privacy provided by various techniques. In
this paper we propose a novel entropy based security measure that can be
applied to any generalisation, restriction or data modification technique. We
use our measure to empirically evaluate and compare a few popular methods,
namely query restriction, sampling and noise addition.Comment: 20 pages, 4 figure
The Fourth Meeting of States Parties to the Convention on Cluster Munitions (2013)
The Fourth Meeting of States Parties (4MSP) took place in Lusaka, Zambia, from 9 to 13 September 2013 and gathered some 464 delegates from 58 States Parties, 18 signatories States, 30 observer States and 12 international organizations (see list below). The 4MSP was opened by Ambassador Steffen Kongstad, President of the 3MSP. During the opening session, H.E Wylbur Simuusa Minster of Foreign Affairs of the Republic of Zambia was elected by the Meeting as President of the 4MSP
Promotion of collaboration between medical and dental professionals
Includes bibliographical references (p. 25-26).published_or_final_versio
miR-31 is consistently inactivated in EBV-associated nasopharyngeal carcinoma and contributes to its tumorigenesis
BACKGROUND: As a distinctive type of head and neck cancers, nasopharyngeal carcinoma (NPC) is genesis from the clonal Epstein-Barr virus (EBV)-infected nasopharyngeal epithelial cells accumulated with multiple genetic lesions. Among the recurrent genetic alterations defined, loss of 9p21.3 is the most frequent early event in the tumorigenesis of EBV-associated NPC. In addition to the reported CDKN2A/p16, herein, we elucidated the role of a miRNA, miR-31 within this 9p21.3 region as NPC-associated tumor suppressor. METHODS: The expression and promoter methylation of miR-31 were assessed in a panel of NPC tumor lines and primary tumors. Its in vitro and in vivo tumor suppression function was investigated through the ectopic expression of miR-31 in NPC cells. We also determined the miR-31 targeted genes and its involvement in the growth in NPC. RESULTS: Downregulation of miR-31 expression was detected in almost all NPC cell line, patient-derived xenografts (PDXs) and primary tumors. Both homozygous deletion and promoter hypermethylation were shown to be major mechanisms for miR-31 silencing in this cancer. Strikingly, loss of miR-31 was also obviously observed in the dysplastic lesions of nasopharynx. Restoration of miR-31 in C666-1 cells inhibited the cell proliferation, colony-forming and migratory capacities. Dramatic reduction of in vitro anchorage-independent growth and in vivo tumorigenic potential were demonstrated in the stable clones expressing miR-31. Furthermore, we proved that miR-31 suppressed the NPC cell growth via targeting FIH1 and MCM2. CONCLUSIONS: The findings provide strong evidence to support miR-31 as a new NPC-associated tumor suppressor on 9p21.3 region. The inactivation of miR-31 may contribute to the early development of NPC.published_or_final_versio
Evasions in Interactions: Examples from the Transcultural Nursing Research Field
Transcultural qualitative research is known for its utility in eliciting in-depth narratives, resulting in increased understanding about cultural phenomena. However, sometimes specific phenomena in the researcher’s inquiry are ignored, evaded, or denied; or a seemingly crucial experience demonstrating society’s unfairness, which the researcher had been expecting, does not emerge. In this paper, the issue of evasions in narratives is addressed, with two examples in which participants evaded the issue about which they were asked: perceptions of discrimination for aging adults of Mexican descent, and perceptions of living with life-limiting illnesses for aging African American adults. The Ethno-Cultural Gerontological Nursing Model framework’s Macro-level factors (climate of stereotypes, attitudes and ascriptions of the majority group) and Group-based influences (“Cultural/historical traditions” and “Cohort influences”) organize our thinking about addressing evasions by minority research participants. Four tools synthesized from the literature and our research experiences are recommended: (1) self-assessment of one’s own cultural values and lenses, (2) co-collaborating during the data collection and analysis phases, (3) acknowledging the power position of the researcher, and (4) over-reading
Garden and landscape-scale correlates of moths of differing conservation status: significant effects of urbanization and habitat diversity
Moths are abundant and ubiquitous in vegetated terrestrial environments and are pollinators, important herbivores of wild plants, and food for birds, bats and rodents. In recent years, many once abundant and widespread species have shown sharp declines that have been cited by some as indicative of a widespread insect biodiversity crisis. Likely causes of these declines include agricultural intensification, light pollution, climate change, and urbanization; however, the real underlying cause(s) is still open to conjecture. We used data collected from the citizen science Garden Moth Scheme (GMS) to explore the spatial association between the abundance of 195 widespread British species of moth, and garden habitat and landscape features, to see if spatial habitat and landscape associations varied for species of differing conservation status. We found that associations with habitat and landscape composition were species-specific, but that there were consistent trends in species richness and total moth abundance. Gardens with more diverse and extensive microhabitats were associated with higher species richness and moth abundance; gardens near to the coast were associated with higher richness and moth abundance; and gardens in more urbanized locations were associated with lower species richness and moth abundance. The same trends were also found for species classified as increasing, declining and vulnerable under IUCN (World Conservation Union) criteria
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