The Rachel Carson Letters and the Making of Silent Spring

Environment, conservation, green, and kindred movements look back to Rachel Carson’s 1962 book Silent Spring as a milestone. The impact of the book, including on government, industry, and civil society, was immediate and substantial, and has been extensively described; however, the provenance of the book has been less thoroughly examined. Using Carson’s personal correspondence, this paper reveals that the primary source for Carson’s book was the extensive evidence and contacts compiled by two biodynamic farmers, Marjorie Spock and Mary T. Richards, of Long Island, New York. Their evidence was compiled for a suite of legal actions (1957-1960) against the U.S. Government and that contested the aerial spraying of dichlorodiphenyltrichloroethane (DDT). During Rudolf Steiner’s lifetime, Spock and Richards both studied at Steiner’s Goetheanum, the headquarters of Anthroposophy, located in Dornach, Switzerland. Spock and Richards were prominent U.S. anthroposophists, and established a biodynamic farm under the tutelage of the leading biodynamics exponent of the time, Dr. Ehrenfried Pfeiffer. When their property was under threat from a government program of DDT spraying, they brought their case, eventually lost it, in the process spent US$100,000, and compiled the evidence that they then shared with Carson, who used it, and their extensive contacts and the trial transcripts, as the primary input for Silent Spring. Carson attributed to Spock, Richards, and Pfeiffer, no credit whatsoever in her book. As a consequence, the organics movement has not received the recognition, that is its due, as the primary impulse for Silent Spring, and it is, itself, unaware of this provenance

Experimental and analytical investigation of a nonaxisymmetric wedge nozzle at static conditions

An experimental investigation of a nonaxisymmetric wedge nozzle was conducted at static conditions. The resulting data, in the form of detailed pressure distributions and oil flow photographs, expand the current nonaxisymmetric nozzle data base. An analytical investigation has been conducted to evaluate a two-dimensional, inviscid, time-dependent theory as a nonaxisymmetric nozzle performance predictor. For the range of nozzle pressure ratios investigated, results indicate good agreement between theory and experiment in regions of predominately two-dimensional flow and limited agreement in regions of three-dimensional flow. For the wedge nozzle and related nozzle configurations, the two dimensional, inviscid theory may be applied as a limited performance predictor

Improving Physiological Relevance of Cell Culture: The Possibilities, Considerations and Future Directions of the Ex Vivo Co-Culture Model

In vitro models provide an important platform for the investigation of cellular growth and atrophy to inform, or extend mechanistic insights from, logistically challenging in vivo trials. While these models allow for the identification of candidate mechanistic pathways, many models involve supraphysiological dosages, non-physiological conditions, or experimental changes relating to individual proteins or receptors, all of which limit translation to human trials. To overcome these drawbacks, the use of ex vivo human plasma and serum has been used in cellular models to investigate changes in myotube hypertrophy, cellular protein synthesis, anabolic and catabolic markers in response to differing age, disease states, and nutrient status. However, there are currently no concurrent guidelines outlining the optimal methodology for this model. This review discusses the key methodological considerations surrounding the use of ex vivoplasma and serum, with a focus in application to skeletal muscle cell lines (i.e., C2C12, L6 and LHCN-M2) and human primary skeletal muscle cells (HSMC) as a means to investigate molecular signaling in models of atrophy and hypertrophy, alongside future directions

Quantum Fluctuations around the Electroweak Sphaleron

We present an analysis of the quantum fluctuations around the electroweak sphaleron and calculate the associated determinant which gives the 1--loop correction to the sphaleron transition rate. The calculation differs in various technical aspects from a previous analysis by Carson et al. so that it can be considered as independent. The numerical results differ also -- by several orders of magnitude -- from those of this previous analysis; we find that the sphaleron transition rate is much less suppressed than found previously.Comment: DO-TH-93/19 39 pages, 5 figures (available on request as Postscript files or via Fax or mail), LaTeX, no macros neede

Ultrareliable, fault-tolerant control systems: A conceptual description

An Ultrareliable, Fault-Tolerant, Control-System (UFTCS) concept is described using a systems design philosophy which allows development of system structures containing virtually no common elements. Common elements limit achievable system reliability and can cause catastrophic loss of fault-tolerant system function. The UFTCS concept provides the means for removing common system elements by permitting the elements of the system to operate as independent, uncoupled entities. Multiple versions of the application program are run on dissimilar hardware. Fault tolerance is achieved through the use of static redundancy management

Atomic and Molecular Opacities for Brown Dwarf and Giant Planet Atmospheres

We present a comprehensive description of the theory and practice of opacity calculations from the infrared to the ultraviolet needed to generate models of the atmospheres of brown dwarfs and extrasolar giant planets. Methods for using existing line lists and spectroscopic databases in disparate formats are presented and plots of the resulting absorptive opacities versus wavelength for the most important molecules and atoms at representative temperature/pressure points are provided. Electronic, ro-vibrational, bound-free, bound-bound, free-free, and collision-induced transitions and monochromatic opacities are derived, discussed, and analyzed. The species addressed include the alkali metals, iron, heavy metal oxides, metal hydrides, $H_2$, $H_2O$, $CH_4$, $CO$, $NH_3$, $H_2S$, $PH_3$, and representative grains. [Abridged]Comment: 28 pages of text, plus 22 figures, accepted to the Astrophysical Journal Supplement Series, replaced with more compact emulateapj versio

Analysis of refill curve shape in ultrasound contrast agent studies

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/135021/1/mp9534.pd

Exact solution (by algebraic methods) of the lattice Schwinger model in the strong-coupling regime

Using the monomer--dimer representation of the lattice Schwinger model, with $N_f =1$ Wilson fermions in the strong--coupling regime ($\beta=0$), we evaluate its partition function, $Z$, exactly on finite lattices. By studying the zeroes of $Z(k)$ in the complex plane $(Re(k),Im(k))$ for a large number of small lattices, we find the zeroes closest to the real axis for infinite stripes in temporal direction and spatial extent $S=2$ and 3. We find evidence for the existence of a critical value for the hopping parameter in the thermodynamic limit $S\rightarrow \infty$ on the real axis at about $k_c \simeq 0.39$. By looking at the behaviour of quantities, such as the chiral condensate, the chiral susceptibility and the third derivative of $Z$ with respect to $1/2k$, close to the critical point $k_c$, we find some indications for a continuous phase transition.Comment: 22 pages (6 figures

Electroweak bubbles and sphalerons

We consider non-perturbative solutions of the Weinberg-Salam model at finite temperature. We employ an effective temperature-dependent potential yielding a first order phase transition. In the region of the phase transition, there exist two kinds of static, spherically symmetric solutions: sphalerons and bubbles. We analyze these solutions as functions of temperature. We consider the most general spherically symmetric fluctuations about the two solutions and construct the discrete modes in the region of the phase transition. Sphalerons and bubbles both possess a single unstable mode. We present simple approximation formulae for these levels.Comment: 14 pages, plain tex, 9 figures appended as postscript files at the end of the paper. THU-93/0

Hausdorff dimension of a quantum string

In the path integral formulation of quantum mechanics, Feynman and Hibbs noted that the trajectory of a particle is continuous but nowhere differentiable. We extend this result to the quantum mechanical path of a relativistic string and find that the ``trajectory'', in this case, is a fractal surface with Hausdorff dimension three. Depending on the resolution of the detecting apparatus, the extra dimension is perceived as ``fuzziness'' of the string world-surface. We give an interpretation of this phenomenon in terms of a new form of the uncertainty principle for strings, and study the transition from the smooth to the fractal phase.Comment: 18 pages, non figures, ReVTeX 3.0, in print on Phys.Rev.