Weight-Based Discrimination in the Italian Labor Market: an Analysis of the Interaction with Gender and Ethnicity

Access to the Italian job market is undermined by several kinds of discrimination influencing the opportunities for individuals to obtain a job. In this study, we analyze together the impact of three of the most relevant kinds of discrimination operating in the Italian labor market: gender, race, and weight. Our aim is to assess whether gender and race either increase or decrease the impact of weight-based discrimination. In this respect, we submit a set of fictitious r\ue9sum\ue9s including photos of either obese or thin applicants in response to real online job offers. Our results indicate that the strongest kind of discrimination operating in the Italian labor market is the one connected to the candidate\u2019s geographical origin. Moreover, we find discrimination based on body weight to be more relevant within immigrants than within natives, and gender gap appears to be higher within the obese candidates\u2019 group compared to the normal-weight candidates\u2019 one. This last result is particularly relevant, as the growing rates of obesity forecasted for the next years could in turn produce an increase in the gender gap, which in Italy is already massive

Immigrants and Italian labor market: statistical or taste-based discrimination?

Types of discrimination are usually distinguished by economic theory in statistical and taste-based. Using a correspondence experiment, we analyze which of the two affects Italian labor market the most. In this respect, we studied the difference in discrimination reserved to first- and second-generation immigrants, taking gender differences into account. Even if we want to admit a rational discrimination based on perceived productivity differences (statistical discrimination) against first-generation immigrants (concerning language and education gaps), the same would not be reasonable for second-generation ones. Since they are born and educated in Italy, where they have always lived, the associated discrimination must be taste-based

Automated calibration of the EPA-SWMM model for a small suburban catchment using PEST: a case study

Rainfall-runoff models must be calibrated and validated before they can be used for urban stormwater management. Manual calibration is very difficult and time-consuming due to the large number of model parameters that must be estimated concurrently. Automatic calibration offers as a promising alternative, ideally supporting a user-independent and time-efficient approach to model parameters estimation. In this article, we test the use of a state-of-the-art standard package (PEST, Parameter ESTimation, http://www.pesthomepage.org/) for the automatic calibration of a rainfall-runoff EPA-SWMM (Storm Water Management Model) model developed for a small suburban catchment. Results reported in the paper demonstrate that the performance of automatically calibrated models still depends on a number of user-dependent choices (the level of catchment discretization, the selection of significant parameters, the optimization techniques adopted). Through a systematic analysis of the results, we try to identify the guidelines for the effective use of automatic calibration procedures based on modeling assumptions and target of the analysis

The willingness to pay of Sicilian consumers for a wine obtained with sustainable production method: An estimate through an ordered probit sample-selection model

The growing presence of Sicilian sustainable wine has pushed the research group to investigate and analyse the consumers' behaviour and their potential willingness to pay a premium price for the wine obtained through sustainable production processes. The analysis of the consumer's behaviour towards the wine made with sustainable production methods is carried out in order to provide potentially useful indications to Italian and in particular Sicilian wine enterprises regarding the production and marketing strategies to undertake in a future perspective. This study shows the result of an empirical investigation on the consumption of sustainable wine in Sicily. Through the Ordered (demographic profile, preference and attitudes), which influence the consumers' choices regarding sustainable wine. The assessment, based on the submission of a questionnaire, has highlighted the willingness to pay a premium price on the part of the 546 consumers interviewed. The study points out that the knowledge of sustainable production methods significantly influences the decision to support a premium price for wine consumption. This attests to the fact that a more attentive and informed consumer is ready to pay more for products obtained according to the principles of environmental sustainability

Intra and inter-day repeatability of peripheral arterial function: suitability and potential limitations

The present study aimed to investigate the inter- and intraday repeatability of reactive hyperemia index (RHI) measured by Endo-PAT in healthy volunteers. Interday RHI repeatability was tested in two consecutive days in a group of thirty-one male subjects. Intraday repeatability was investigated at baseline and after 2 and 4 h in a group of sixteen volunteers. Data were evaluated by analysis of variance. Bland-Altman plot, coefficient of variation (CV), coefficient of repeatability (CR) and intraclass correlation coefficient (ICC) were measured. While interday RHI repeatability was found to be reliable (CV: 6.0%; CR: 0.51; ICC: 0.77), multiple evaluations within the same day significantly (p<0.001) affected RHI (repeatability of the measurement - CV: 18.8%; CR: 1.26; ICC: 0.48). In particular, a significant increase in RHI occurred at 4 h compared to 2 h (+16.8%; p<0.05) and to baseline (+30.1%; p<0.05). In conclusion, RHI showed good interday but poor intraday repeatability. Multiple evaluations increased RHI especially in subjects with endothelial dysfunction who improved or reversed their impairment. These results show the potential limitations of multiple Endo-PAT measurements within the same day and the importance of standardizing the protocols before RHI evaluations

To be or not to be a germ cell: The extragonadal germ cell tumor paradigm

In the human embryo, the genetic program that orchestrates germ cell specification in-volves the activation of epigenetic and transcriptional mechanisms that make the germline a unique cell population continuously poised between germness and pluripotency. Germ cell tumors, neo-plasias originating from fetal or neonatal germ cells, maintain such dichotomy and can adopt either pluripotent features (embryonal carcinomas) or germness features (seminomas) with a wide range of phenotypes in between these histotypes. Here, we review the basic concepts of cell specification, migration and gonadal colonization of human primordial germ cells (hPGCs) highlighting the analogies of transcriptional/epigenetic programs between these two cell types

UV and genotoxic stress induce ATR relocalization in mouse spermatocytes

During meiosis, phosphorylation of H2AX is one of the earliest cellular responses to the generation of DNA double-strand breaks (DSBs) by the SPO11 topoisomerase. ATM is the kinase which mediates the formation of phosphorylated H2AX (H2AX) meiotic foci, while ATR is the kinase which signals chromosome asynapsis at the level of the XY bivalent. To investigate the possible role of ATR also in DNA damage signalling in meiotic cells, we studied the effect of UV radiation and chemotherapy drugs on H2AX phosphorylation and ATR relocalization in mouse pachytene spermatocytes. Here, we report that UV, a single strand break DNA-damaging agent, induces ATR relocalization from the XY sex body to nuclear foci and intense H2AX phosphorylation. Other DNA damage proteins such as MDC1, NBS1 and 53BP1 showed a similar relocalization following UVA microirradiation of spermatocytes. We found that DNA damage induced by UV increased the intensity and the number of H2AX foci also in Atm null spermatocytes. Inhibition of RNA synthesis was found to induce the formation of H2AX foci, but it did not influence the DNA damage response to UV irradiation. Finally, exposure of spermatocytes to double strand break DNA-damaging agents such as cisplatin, bleomycin or etoposide also induced ATR relocalization and intense H2AX phosphorylation and led to anomalies in synaptonemal assembly. Our results demonstrate that DNA damage induced by genotoxic stress can activate ATR and influence meiotic chromatin remodelling through H2AX phosphorylation, likely as part of a response which normally ensures germ cell genomic integrity

On the Design of Sidelink for Cellular V2X: A Literature Review and Outlook for Future

Connected and fully automated vehicles are expected to revolutionize our mobility in the near future on a global scale, by significantly improving road safety, traffic efficiency, and traveling experience. Enhanced vehicular applications, such as cooperative sensing and maneuvering or vehicle platooning, heavily rely on direct connectivity among vehicles, which is enabled by sidelink communications. In order to set the ground for the core contribution of this paper, we first analyze the main streams of the cellular-vehicle-to-everything (C-V2X) technology evolution within the Third Generation Partnership Project (3GPP), with focus on the sidelink air interface. Then, we provide a comprehensive survey of the related literature, which is classified and critically dissected, considering both the Long-Term Evolution-based solutions and the 5G New Radio-based latest advancements that promise substantial improvements in terms of latency and reliability. The wide literature review is used as a basis to finally identify further challenges and perspectives, which may shape the C-V2X sidelink developments in the next-generation vehicles beyond 5G

Effect of acute cigarette smoking on blood pressure and peripheral endothelial function in young healthy male smokers: preliminary data

Smoking is one of the major risk factors for atherosclerosis associated with premature coronary and artery diseases. Endothelial dysfunction is an early event in atherosclerosis, and seems mainly related to the decreased production or availability of nitric oxide in smokers. The objective of the study is to investigate the effect of a single cigarette on blood pressure and peripheral arterial function in young moderate smokers (approximately 15 cigarettes/day)