Physical activity habits of the ESPN pupils and its relation with health pointers

This study intends to characterize habits and preferences concerned with physical activity of the Secondary School Pedro Nunes students. Moreover, we intended to understand the relation between some aspects of physical activity (volume: number of hours/week) and practice type (formal and informal practice) and health indicators: body composition, aerobic and muscular ability. With this study we also wish to promote among the scholar field the discussion on the role of the school and the physical education in the development and maintenance of the physical aptitude of the young people and the adoption of healthful habits of life.FCT (Fundação para a Ciência e a Tecnologia), IDP (Instituto do Desporto de Portugal), AIESEP World Congres

In vitro cytocompatibility evaluation of poly(DL-lactic acid) scaffolds loaded with minocycline and voriconazole addressing osteomyelitis

Osteomyelitis or bone infection is an acute or chronic inflammatory process involving the bone and its structures, secondary to infection with pyogenic organisms, such as bacteria and fungi. Considering the associated high patient economic burden, morbidity, and mortality, it is essential to develop novel strategies for osteomyelitis management. Porous scaffolds based on biomaterials may locally deliver high concentrations of antibiotics, an effective strategy in eradicating bone infection. When incorporating bioactive bioglasses and bioresorbable polymers like poly(DL-lactic acid) (PDLLA), these structures exhibit biosafety, biodegradability, and the expected global structure to promote cell expansion and cell differentiation, being critical to consider and evaluate their biocompatibility compliance. As the encapsulation of more than one active pharmaceutical ingredient is an attractive approach, the present study focuses on the cytocompatibility evaluation of an innovative system based on the dual delivery of two antimicrobials, an antibiotic that enhances bone formation, minocycline (MH), and an antifungal agent with a broad spectrum of activity, voriconazole (VCZ), aiming bone infection therapeutics. Scaffolds were prepared by solvent casting/particulate leaching techniques and functionalized with bioglass. The scaffolds produced were adsorbed with 0.5 or 0.1 mg/mL of minocycline and also with 0.1 mg/mL of voriconazole. To test the bio-functionality and the biological safety of scaffolds, in vitro cell assays were achieved employing the MG-63 cell line (ATCC® CRL-1427TM human osteoblast cell line). The AlamarBlue® assay was used to measure cell proliferation in the scaffold. As osteoblast differentiation markers, the following were determined: alkaline phosphatase activity and mineralization using Alizarin red assay, an indicator of in vitro bone formation. All scaffolds sustained the proliferation of metabolically active cells, nonetheless, scaffolds adsorbed with the highest concentration of MH (0.5 mg/mL) presented a significant (p<0.05) cytotoxic effect. Matrix maturation assays supported early osteoblasts differentiation and the osteoinductive role of minocycline described in the literature was also highlighted. Matrix mineralization analysis showed the highest value associated with scaffolds with both antimicrobials adsorbed. Once the described scaffolds enhanced osteoblasts' differentiation, and matrix mineralization and evidenced no cytotoxic effects, they come to light as an auspicious alternative for local antimicrobial therapy addressing osteomyelitis prevention and therapeutics.info:eu-repo/semantics/publishedVersio

Rendimento da extração de óleos essenciais de frutos quiropterocóricos maduros e imaturos.

EVINCI. Resumo 022

Orbital forcing of stratal patterns in an inner platform carbonate sucession: an example from an Upper Hauterivian series of the Lusitanian Basin, Portugal

With an example taken from a late-Hauterivian series of the Lusitanian Basin (Portugal), we will demonstrate the sedimentary record of orbital pattern variations and, consequently, climate variations in an inner platform environment with patterns and isolation changes, allows us to establish 4 major orders of periodicity related to orbital components:- The large cycles ob bed thickness variation, constituted by 31-32 beds, recording the 400 ky eccentricity cycle component;- The medium cycles, represented by byndles of 8-9 beds, related to the 100 ky eccentricity cycle component; - The small cycles, of 3-5 beds, recording the 41 ky obliquity components;- The very small cycles, of 2 beds, related to the 22 ky and 26 ky precession components. The mean duration of each bed is around 11.8 ky, a number very close to that of the precession hemi-cycle. Climatic control on qualitative production is confirmed by the close relation between the bed thickness variations, the insolation variability and the variation of micritized elements concentrations

Goodness of fit comparisons among five bayesian models in genome-wide association of tick resistance in brazilian Hereford and Braford beef cattle.

This study aimed to compare five models fitness and top effect SNPs obtained with three different Bayesian GWAS methods applied to cattle tick resistance in Braford and Hereford

Depressive symptoms and alcohol correlates among Brazilians aged 14 years and older: a cross-sectional study

Background: the associations between depressive symptoms and alcohol-related disorders, drinking patterns and other characteristics of alcohol use are important public health issues worldwide. This study aims to study these associations in an upper middle-income country, Brazil, and search for related socio-demographic correlations in men and women.Methods: A cross-sectional study was conducted between November 2005 and April 2006. the sample of 3,007 participants, selected using a multistage probabilistic sampling method, represents the Brazilian population aged 14 and older. Depressive symptoms were assessed using the Center for Epidemiologic Studies Depression Scale and alcohol dependence was assessed using the Composite International Diagnostic Interview. Associations assessed using bi-variate analysis were tested using Rao-Scott measures. Gender specific multinomial logistic regression models were developed.Results: Among the participants with alcohol dependence, 46% had depressive symptoms (17.2% mild/moderate and 28.8% major/severe; p < 0.01); 35.8% (p = 0.08) of those with alcohol abuse and 23.9% (p < 0.01) of those with a binge-drinking pattern also had depressive symptoms. Alcohol abstainers and infrequent drinkers had the highest prevalence of major/severe depressive symptoms, whereas frequent heavy drinkers had the lowest prevalence of major/severe depressive symptoms. in women, alcohol dependence and the presence of one or more problems related to alcohol consumption were associated with higher risks of major/severe depressive symptoms. Among men, alcohol dependence and being = 45 years old were associated with higher risks of major/severe depressive symptoms.Conclusions: in Brazil, the prevalence of depressive symptoms is strongly related to alcohol dependence; the strongest association was between major/severe depressive symptoms and alcohol dependence in women. This survey supports the possible association of biopsychosocial distress, alcohol consumption and the prevalence of depressive symptoms in Brazil. Investing in education, social programs, and care for those with alcohol dependence and major/severe depressive symptoms, especially for such women, and the development of alcohol prevention policies may be components of a strategic plan to reduce the prevalence of depression and alcohol problems in Brazil. Such a plan may also promote the socio-economic development of Brazil and other middle-income countries.Universidade Federal de São Paulo UNIFESP, Department Psychiat, BR-15085420 Sao Jos Rio Preto, SP, BrazilUniv São Paulo FMRP, Ribeirao Preto Med Sch, Dept Social Med, BR-14049900 Ribeirao Preto, SP, BrazilUniv Fed Santa Catarina, Ctr Ciencias Saude, Dept Clin Med, BR-88040900 Florianopolis, SC, BrazilUniv Texas Dallas, Dallas Reg Campus, Sch Publ Hlth, Dallas, TX 75390 USAUniv São Paulo, FMRP USP, Ribeirao Preto Med Sch, Dept Neurosci & Behav, BR-14048900 Ribeirao Preto, SP, BrazilINCT Translat Med, São Paulo, BrazilUniversidade Federal de São Paulo UNIFESP, Department Psychiat, BR-15085420 Sao Jos Rio Preto, SP, BrazilWeb of Scienc

Teores foliares de cálcio e boro no feijoeiro influenciados pelo tempo de molhamento da água de irrigação por pivô-central.

A lavagem de nutrientes das folhas de plantas pela água das chuvas é um fato reconhecido no meio agronômico. Com o advento da prática de irrigação de grandes áreas, em diferentes culturas, o fenômeno ainda não mereceu a atenção necessária. O objetivo do estudo foi determinar o conteúdo foliar de cálcio e boro no limbo foliar do feijão, em razão do tempo de molhamento da planta, ocasionado pelo tempo de operação do pivô-central, em quatro diferentes pontos de localização no campo, ao longo do raio do equipamento. O estudo foi conduzido no município de Cristalina - GO, em uma lavoura de feijão, de propriedade particular, irrigada pelo sistema de irrigação por pivô-central. A cultivar utilizada foi a BRS FC402. No início do florescimento da cultura, foram coletadas amostras de folhas da planta para análise foliar. Até aquele momento de coleta das amostras, a cultura tinha recebido 150 mm de água de irrigação. As amostras foram coletadas em quatro pontos equidistantes ao longo do raio do pivô-central, com quatro repetições. Foram analisados os teores de cálcio e boro no limbo foliar. Os teores desses nutrientes foram tanto maiores quanto menores os tempos de molhamento foliar pela água de irrigação