Fibonacci type semigroups

We study "Fibonacci type" groups and semigroups. By establishing asphericity of their presentations we show that many of the groups are infinite. We combine this with Adjan graph techniques and the classification of the finite Fibonacci semigroups (in terms of the finite Fibonacci groups) to extend it to the Fibonacci type semigroups

Automatic structures for semigroup constructions

We survey results concerning automatic structures for semigroup constructions, providing references and describing the corresponding automatic structures. The constructions we consider are: free products, direct products, Rees matrix semigroups, Bruck-Reilly extensions and wreath products.Comment: 22 page

The effect of organic structures on the water stability of macro-aggregates.

Non-Peer ReviewedA study was conducted to identify the chemical structures of soil organic matter and examine their effect on the water stability of macro-aggregates (>250 um) in a SiL Brown Chernozem under wheat-fallow (WF) and continuous wheat (CW) . The proportion of water stable macro-aggregates were determined by wet sieving. Chemical structures of soil organic matter were characterized by pyrolysis field ionization mass spectrometry (Py-FIMS), and grouped into seven classes: carbohydrates, phenolic and lignin monomers, lignin dimers, lipids + alkanes and alkenes, sterols, alkyl aromatic and N-compounds. In comparison with CW, there was a reduction in the proportion of macro-aggregates and an increase of micro-aggregates in the WF crop rotation. Sixty-five percent of all the soil organic matter (SOM) was identified by Py-FIMS. The average concentration of each class of compound in whole soil and macro-aggregate samples ranged between 0.1 and 15% of the total identified SOM. Carbohydrates, phenolic, and lignin monomers were the most abundant compounds (>10%). Linear regression models (r2 ~ 0.96, p=0.05) showed that the stability of macro-aggregates was highly correlated with the concentration of the least abundant (<3. 5%) structures of sterols, lipids and lignin dimers. These compounds are metabolic products of plants and soil organisms

The Individual Day-to-Day Process of Social Anxiety in Vulnerable College Students

Transitions requiring the creation of new social networks may be challenging for individuals vulnerable to social anxiety, which may hinder successful adjustment. Using person-specific methodology, this study examined social anxiety in vulnerable university freshman away from home during their first semester of college to understand how day-to-day processes of social anxiety influenced future social anxiety and social withdrawal. Participants completed daily measures of four components of social anxiety which were examined as a process during a single day, and as a process affecting social anxiety and social withdrawal the next day. For most individuals, same day fear of negative evaluation was associated with maladaptive cognitive processes (anticipatory processing and post-event rumination) and influenced social withdrawal behaviors. Across time relations were less robust and varied between participants suggesting the importance of situational factors and individual differences. These findings may have implications for the effectiveness of various intervention strategies

Scoping biological indicators of soil quality Phase II. Defra Final Contract Report SP0534

This report presents results from a field assessment of a limited suite of potential biological indicators of soil quality to investigate their suitability for national-scale soil monitoring

The NF-κB subunit c-Rel regulates Bach2 tumour suppressor expression in B-cell lymphoma

The REL gene, encoding the NF-κB subunit c-Rel, is frequently amplified in B-cell lymphoma and functions as a tumour-promoting transcription factor. Here we report the surprising result that c-rel–/– mice display significantly earlier lymphomagenesis in the c-Myc driven, Eμ-Myc model of B-cell lymphoma. c-Rel loss also led to earlier onset of disease in a separate TCL1-Tg-driven lymphoma model. Tumour reimplantation experiments indicated that this is an effect intrinsic to the Eμ-Myc lymphoma cells but, counterintuitively, c-rel–/– Eμ-Myc lymphoma cells were more sensitive to apoptotic stimuli. To learn more about why loss of c-Rel led to earlier onset of disease, microarray gene expression analysis was performed on B cells from 4-week-old, wild-type and c-rel–/– Eμ-Myc mice. Extensive changes in gene expression were not seen at this age, but among those transcripts significantly downregulated by the loss of c-Rel was the B-cell tumour suppressor BTB and CNC homology 2 (Bach2). Quantitative PCR and western blot analysis confirmed loss of Bach2 in c-Rel mutant Eμ-Myc tumours at both 4 weeks and the terminal stages of disease. Moreover, Bach2 expression was also downregulated in c-rel–/– TCL1-Tg mice and RelA Thr505Ala mutant Eμ-Myc mice. Analysis of wild-type Eμ-Myc mice demonstrated that the population expressing low levels of Bach2 exhibited the earlier onset of lymphoma seen in c-rel–/– mice. Confirming the relevance of these findings to human disease, analysis of chromatin immunoprecipitation sequencing data revealed that Bach2 is a c-Rel and NF-κB target gene in transformed human B cells, whereas treatment of Burkitt's lymphoma cells with inhibitors of the NF-κB/IκB kinase pathway or deletion of c-Rel or RelA resulted in loss of Bach2 expression. These data reveal a surprising tumour suppressor role for c-Rel in lymphoma development explained by regulation of Bach2 expression, underlining the context-dependent complexity of NF-κB signalling in cancer