46 research outputs found

    Tidal signatures in mesospheric turbulence

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    We search for the presence of tidal signatures in high latitude mesospheric turbulence as parameterized by turbulent energy dissipation rate estimated using a medium frequency radar, quantifying our findings with the aid of correlation analyses. A diurnal periodicity is not particularly evident during the winter and spring months but is a striking feature of the summer mesopause. While semidiurnal variation is present to some degree all year round, it is particularly pronounced in winter. We find that the maximum in the summer 24-h variation corresponds to that of the westward phase of the diurnal tide, and that the maximum in the winter 12 h variation corresponds to that of the southward phase of the semidiurnal tide. This information is used to infer the horizontal propagation direction of gravity waves: during the summer the eastward direction is consistent with closure of the summer vortex, while in winter the inferred directions require more complex arguments

    Vertical and interhemispheric links in the stratosphere-mesosphere as revealed by the day-to-day variability of Aura-MLS temperature data

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    The coupling processes in the middle atmosphere have been a subject of intense research activity because of their effects on atmospheric circulation, structure, variability, and the distribution of chemical constituents. In this study, the day-to-day variability of Aura-MLS (Microwave Limb Sounder) temperature data are used to reveal the vertical and interhemispheric coupling processes in the stratosphere-mesosphere during four Northern Hemisphere winters (2004/2005–2007/2008). The UKMO (United Kingdom Meteorological Office) assimilated data and mesospheric winds from MF (medium frequency) radars are also applied to help highlight the coupling processes. In this study, a clear vertical link can be seen between the stratosphere and mesosphere during winter months. The coolings and reversals of northward meridional winds in the polar winter mesosphere are often observed in relation to warming events (Sudden Stratospheric Warming, SSW for short) and the associated changes in zonal winds in the polar winter stratosphere. An upper-mesospheric cooling usually precedes the beginning of the warming in the stratosphere by 1–2 days. Inter-hemispheric coupling has been identified initially by a correlation analysis using the year-to-year monthly zonal mean temperature. Then the correlation analyses are performed based upon the daily zonal mean temperature. From the original time sequences, significant positive (negative) correlations are generally found between zonal mean temperatures at the Antarctic summer mesopause and in the Arctic winter stratosphere (mesosphere) during northern mid-winters, although these correlations are dominated by the low frequency variability (i.e. the seasonal trend). Using the short-term oscillations (less than 15 days), the statistical result, by looking for the largest magnitude of correlation within a range of time-lags (0 to 10 days; positive lags mean that the Antarctic summer mesopause is lagging), indicates that the temporal variability of zonal mean temperature at the Antarctic summer mesopause is also positively (negatively) correlated with the polar winter stratosphere (mesosphere) during three (2004/2005, 2005/2006, and 2007/2008) out of the four winters. The highest value of the correlation coefficient is over 0.7 in the winter-stratosphere for the three winters. The remaining winter (2006/2007) has more complex correlations structures; correspondingly the polar vortex was distinguished this winter. The time-lags obtained for 2004/2005 and 2006/2007 are distinct from 2005/2006 and 2007/2008 where a 6-day lag dominates for the coupling between the winter stratosphere and the summer mesopause. The correlations are also provided using temperatures in northern longitudinal sectors in a comparison with the Antarctic-mesopause zonal mean temperature. For northern mid-high latitudes (~50–70° N), temperatures in Scandinavia-Eastern Europe and in the Pacific-Western Canada longitudinal sectors often have opposite signs of correlations with zonal mean temperatures near the Antarctic summer mesopause during northern mid-winters. The statistical results are shown to be associated with the Northern Hemisphere's polar vortex characteristics

    A functional spleen contributes to afucosylated IgG in humans

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    As a lymphoid organ, the spleen hosts a wide range of immune cell populations, which not only remove blood-borne antigens, but also generate and regulate antigen-specific immune responses. In particular, the splenic microenvironment has been demonstrated to play a prominent role in adaptive immune responses to enveloped viral infections and alloantigens. During both types of immunizations, antigen-specific immunoglobulins G (IgGs) have been characterized by the reduced amount of fucose present on N-linked glycans of the fragment crystallizable (Fc) region. These glycans are essential for mediating the induction of immune effector functions. Therefore, we hypothesized that a spleen may modulate humoral responses and serve as a preferential site for afucosylated IgG responses, which potentially play a role in immune thrombocytopenia (ITP) pathogenesis. To determine the role of the spleen in IgG-Fc glycosylation, we performed IgG subclass-specific liquid chromatography-mass spectrometry (LC-MS) analysis of Fc glycosylation in a large cohort of individuals splenectomized due to trauma, due to ITP, or spherocytosis. IgG-Fc fucosylation was consistently increased after splenectomy, while no effects for IgG-Fc galactosylation and sialylation were observed. An increase in IgG1- and IgG2/3-Fc fucosylation level upon splenectomy has been reported here for the first time, suggesting that immune responses occurring in the spleen may be particularly prone to generate afucosylated IgG responses. Surprisingly, the level of total IgG-Fc fucosylation was decreased in ITP patients compared to healthy controls. Overall, our results suggest a yet unrecognized role of the spleen in either the induction or maintenance of afucosylated IgG responses by B cells.Proteomic

    The commune of Lucca 1369-1400 and the rise of the Guinigi Signoria

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    SIGLELD:D45137/83(2vols) / BLDSC - British Library Document Supply CentreGBUnited Kingdo

    Isolated lower mesospheric echoes seen by medium frequency radar at 70Âş N, 19Âş E

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    We have noted sporadic instances of strong isolated reflections of medium frequency (MF) radar waves from the mesosphere from as low as 50 km altitude and have devised a set of criteria for isolating these apparently anomalous echoes from those normally occurring from progressive partial reflections in the D-region. The object of this study is to map the occurrences of such echoes facilitating comparisons with other observations. For example, the similarity and simultaneity of the echo structure for the 20 January 2005 with VHF radar results presented by LĂĽbken et al. (2006) are particularly striking. In presenting a number of such echo events since 2001 selected from the MF radar dataset (which spans 1997 to present), we find that virtually all echo occurrences coincide with enhanced solar proton fluxes suggesting that substantial ionisation of the mesosphere is a necessary condition. Strong partial reflections of the radio wave in the lower mesosphere combined with seasonally varying total absorption higher up, thus giving false impressions of lower mesospheric layers preferentially in winter, constitute a scenario consistent with our observations

    Testing the hypothesis of the influence of neutral turbulence on the deduction of ambipolar diffusivities from meteor trail expansion

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    Fading times of radar echoes from underdense meteor trails in the upper mesosphere/lower thermosphere are commonly used to determine ambipolar diffusivities and hence ambient temperature. Diffusivities are generally expected to increase exponentially with height through the region from which the meteor trail echoes are obtained, viz., typically 70-110km altitude for a ~30-MHz radar. In practice, however, this is more the exception: unexpectedly large diffusivities are obtained in the lower part of the regime, and unexpectedly low values are obtained in the upper part; only in the few kilometres on either side of the maximum in echo occurrence (viz., 90km for a 30-MHz radar) does the diffusivity profile behave as expected. Hall (2002) hypothesised that neutral turbulence might be enhancing expansion of the meteor trail in the lower part of the regime. In this communication, due to results only available since the publication of Hall's suggestion, we are able to refute the hypothesis

    Relationship between variability of the semidiurnal tide in the Northern Hemisphere mesosphere and quasi-stationary planetary waves throughout the global middle atmosphere

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    To investigate possible couplings between planetary waves and the semidiurnal tide (SDT), this work examines the statistical correlations between the SDT amplitudes observed in the Northern Hemisphere (NH) mesosphere and stationary planetary wave (SPW) with wavenumber S=1 (SPW1) amplitudes throughout the global stratosphere and mesosphere. The latter are derived from the Aura-MLS temperature measurements. During NH summer-fall (July–October), the mesospheric SDT amplitudes observed at Svalbard (78° N) and Eureka (80° N) usually do not show persistent correlations with the SPW1 amplitudes in the opposite hemisphere. Although the SDT amplitudes observed at lower latitudes (~50–70° N), especially at Saskatoon (52° N), are often shown to be highly and positively correlated with the SPW1 amplitudes in high southern latitudes, these correlations cannot be sufficiently explained as evidence for a direct physical link between the Southern Hemisphere (SH) winter-early spring SPW and NH summer-early fall mesospheric SDT. This is because the migrating tide's contribution is usually dominant in the mid-high latitude (~50–70° N) NH mesosphere during the local late summer-early fall (July–September). The numerical correlation is dominated by similar low-frequency variability or trends between the amplitudes of the NH SDT and SH SPW1 during the respective equinoctial transitions. In contradistinction, during NH winter (November–February), the mesospheric SDT amplitudes at northern mid-high latitudes (~50–80° N) are observed to be significantly and positively correlated with the SPW1 amplitudes in the same hemisphere in most cases. Because both the SPW and migrating SDT are large in the NH during the local winter, a non-linear interaction between SPW and migrating SDT probably occurs, thus providing a global non-migrating SDT. This is consistent with observations of SDT in Antarctica that are large in summer than in winter. It is suggested that climatological hemispheric asymmetry, e.g. the SH and NH winter characteristics are substantially different, lead to differences in the inter-hemispheric SPW-tide physical links

    Springtime transitions in mesopause airglow and dynamics: photometer and MF radar observations in the Scandinavian and Canadian sectors

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    Observations from 2 optical ground stations and 3 MF radars at high and mid-latitudes have been combined to describe "springtime transitions" in atomic oxygen and the mesopause wind fields and waves for eight years (1991-1998). The typical signature in the Stockholm (60degreesN, 20degreesE) OI 558 nm 'green-line' emission involves a rapid (circa) 2-days rise in the nighttime value by factors of 2 or so, with a subsequent decrease by factors of 3-10. There is considerable inter-annual variability in these green-line emissions, and also the hydroxyl airglow (intensities and temperatures) at Bear Lake Observatory (Utah, 42degreesN, 115degreesW), but the 6-8 year means do show a characteristic airglow "springtime transition" (AST) near the end of March. MF radars from Tromso (70degreesN, 19degreesE), Juliusruh (55 N, 13 E) and Saskatoon (52degreesN, 107degreesW) demonstrate springtime reversals in the mean (daily) zonal winds at 85-95 km, both annually and in B year means, at times near the airglow "transitions". The "tongue" of easterlies (near March 30) is a long-established feature of mesopause dynamics, and clear indications of associated changes in tides and gravity wave fluxes are also presented. The TIME-GCM is also used to investigate the characteristics of the airglow and winds during the interval associated with the AST events. Useful similarities with the observed variations are demonstrated

    Asymmetry in the interhemispheric planetary wave-tide link between the two hemispheres

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    This study assesses the relation between the year-to-year variability of the semidiurnal tides (SDT) observed at high latitudes of both hemispheres and the global stratospheric stationary planetary wave (SPW) with zonal wavenumber S=1 (SPW1) derived from the UKMO temperature data. No significant positive correlation can be identified between the interannual variability of the Northern Hemisphere (NH) SDT and the Southern Hemisphere (SH) SPW1 for austral late-winter months. In contrast, a good consistency is evident for the interannual variations between the SDT observed at Rothera (68°S, 68°W) and the Arctic SPW1 for NH mid-winter months. Since it has been observed that during austral summer the non-migrating SDT often plays a significant role at the latitude of Rothera, a physical link between the SH SDT and the NH SPW is suggested. This asymmetry in the interhemispheric link is also noted in a recent study
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