Immobilized photosensitizers for antimicrobial applications

Photodynamic antimicrobial chemotherapy (PACT) is a very promising alternative to conventional antibiotics for the efficient inactivation of pathogenic microorganisms; this is due to the fact that it is virtually impossible for resistant strains to develop due to the mode of action employed. PACT employs a photosensitizer, which preferentially associates with the microorganism, and is then activated with non-thermal visible light of appropriate wavelength(s) to generate high localized concentrations of reactive oxygen species (ROS), inactivating the microorganism. The concept of using photosensitizers immobilized on a surface for this purpose is intended to address a range of economic, ecological and public health issues. Photosensitising molecules that have been immobilized on solid support for PACT applications are described herein. Different supports have been analyzed as well as the target microorganism and the effectiveness of particular combinations of support and photosensitiser

American Railway Express Company - Holmes Funeral Directors, May 24, 1926

Correspondence: Letter from C.W. Turner, Superintendent, American Railway Express Company, Jacksonville Florida, request of payment

The use of satellites in non-goestationary orbits for unloading geostationary communication satellite traffic peaks. Volume 2: Technical report

The part of the geostationary (GEO) orbital arc used for United States domestic fixed, communications service is rapidly becoming filled with satellites. One of the factors currently limiting its utilization is that communications satellites must be designed to have sufficient capacity to handle peak traffic leads, and thus are under utilized most of the time. A solution is to use satellites in suitable non-geostationary orbits to unload the traffic peaks. Three different designs for a non-geostationary orbit communications satellite system are presented for the 1995 time frame. The economic performance is analyzed and compared with geostationary satellites for two classes of service, trunking and customer premise service. The result is that the larger payload of the non-geostationary satellite offsets the burdens of increased complexity and worse radiation environment to give improved economic performance. Depending on ground terminal configuration, the improved economic performance of the space segment may be offset by increased ground terminal expenses

Manual for extending the laser specklegram technique to strain analysis of rotating components

The theory, techniques, and equipment necessary for extending laser speckle techniques to analyze stresses in rotating blades are described. Details for setting up the equipment, for timing the events, for data recording, and for data analysis are discussed. Finite element techniques are investigated for analysis of speckle data. Advantages and limitations of the finite element analysis for the speckle data are discussed. The finite element program is listed

Development of basic theories and techniques for determining stresses in rotating turbine or compressor blades

A method for measuring in-plane displacement of a rotating structure by using two laser speckle photographs is described. From the displacement measurements one can calculate strains and stresses due to a centrifugal load. This technique involves making separate speckle photographs of a test model. One photograph is made with the model loaded (model is rotating); the second photograph is made with no load on the model (model is stationary). A sandwich is constructed from the two speckle photographs and data are recovered in a manner similar to that used with conventional speckle photography. The basic theory, experimental procedures of this method, and data analysis of a simple rotating specimen are described. In addition the measurement of in-plane surface displacement components of a deformed solid, and the application of the coupled laser speckle interferometry and boundary-integral solution technique to two dimensional elasticity problems are addressed

Feasibility study of an Integrated Program for Aerospace vehicle Design (IPAD). Volume 2: The design process

The extent to which IPAD is to support the design process is identified. Case studies of representative aerospace products were developed as models to characterize the design process and to provide design requirements for the IPAD computing system

Analysis of effects of macroscopic propagation and multiple molecular orbitals on the minimum in high-order harmonic generation of aligned CO2_{2}

We report theoretical calculations on the effect of the multiple orbital contribution in high-order harmonic generation (HHG) from aligned CO$_2$ with inclusion of macroscopic propagation of harmonic fields in the medium. Our results show very good agreements with recent experiments for the dynamics of the minimum in HHG spectra as laser intensity or alignment angle changes. Calculations are carried out to check how the position of the minimum in HHG spectra depends on the degrees of molecular alignment, laser focusing conditions, and the effects of alignment-dependent ionization rates of the different molecular orbitals. These analyses help to explain why the minima observed in different experiments may vary.Comment: 7 figure

Atmospheric environment for space shuttle (STS-8) launch

Selected atmospheric conditions observed near Space Shuttle STS-8 launch time on August 30, 1983, at Kennedy Space Center, Florida are summarized. Values of ambient pressure, temperature, moisture, ground winds, visual observations (cloud), and winds aloft are included. The sequence of prelaunch Jimsphere measured vertical wind profiles is given. Also presented are wind and thermodynamic parameters representative of surface and aloft conditions in the SRB descent/impact ocean area. Final meteorological tapes, which consist of wind and thermodynamic parameters versus altitude, for STS-8 vehicle ascent and SRB descent/impact were constructed. The STS-8 ascent meteorological data tape was constructed

Does a loaded warm-up influence jump asymmetry and badminton-specific change of direction performance?

Purpose: Previously, it has been shown that loaded warm-up (LWU) can improve change of direction speed (CODS) in professional badminton players. However, the effect of asymmetry on CODS in badminton players and the influence of LWU on asymmetry has not been examined. Methods: Twenty-one amateur badminton players (age: 29.5 ± 8.4; playing experience: 8.4 ± 4.2 years) completed two trials. In the first, they performed a control warm-up (CWU). In the second, they performed the same warm-up but with three exercises loaded with a weight vest (LWU). Following both warm-ups, players completed single leg jump (SLCMJ) and badminton-specific CODS tests. Results: No significant differences between CWU and LWU were observed for CODS, SLCMJ or SLCMJ asymmetry. However, small effect sizes suggested faster CODS (mean difference: -5%; d = -0.32) and lower asymmetries (mean difference: -3%; d = -0.39) following LWU. Five players (24%) experienced CODS improvements greater than the minimum detectable change whilst two (10%) responded negatively. Asymmetry was not correlated with CODS following CWU (ρ = 0.079; p = 0.733) but was negatively associated with CODS after LWU (ρ = -0.491; p = 0.035). Conclusion: LWU may prove a strategy to trial on an individual basis but generic recommendations should not be applied