Management of Postsurgical Hyperhidrosis With Direct Current and Tap Water

Background and Purpose. Excessive sweating, known as hyperhidrosis, involves the eccrine sweat glands of the axillae, soles, palms, and/or forehead. The use of iontophoresis to reduce or eliminate excessive sweating has been described since 1952. The purpose of this case report is to describe the use of tap water galvanism (TWG) using direct current (DC) with a patient who had postsurgical hyperhidrosis. Case Description. The patient was a 36-year-old male electrician with traumatic phalangeal amputation and postsurgical development of hyperhidrosis. Tap water galvanism was administered using a DC generator, 2 to 3 times per week for 10 treatments. The patient\u27s hands were individually submerged in 2 containers of tap water with the electrodes immersed directly into the containers. Each hand was treated with 30 minutes of TWG at 12 mA. Hyperhidrosis was measured by a 5-second imprint and subsequent tracing of the left hand placed on dry paper toweling. Outcomes. The patient\u27s hyperhidrosis decreased from the full left palmar pad, with a surface area of 10.3×12.0 cm, to a reduced area of wetness that covered a 2.2-×2.7-cm area. The patient returned to work as an electrician without needing absorbent gloves, which had prevented him from performing electrical work. Discussion. Following use of TWG, the patient\u27s palmar hyperhidrosis returned to normhidrosis

Extracting Electric Polarizabilities from Lattice QCD

Charged and neutral, pion and kaon electric polarizabilities are extracted from lattice QCD using an ensemble of anisotropic gauge configurations with dynamical clover fermions. We utilize classical background fields to access the polarizabilities from two-point correlation functions. Uniform background fields are achieved by quantizing the electric field strength with the proper treatment of boundary flux. These external fields, however, are implemented only in the valence quark sector. A novel method to extract charge particle polarizabilities is successfully demonstrated for the first time.Comment: 17 pages, 6 figures, a few clarifications added, published versio

Differential Regulation of Growth-Promoting Signalling Pathways by E-Cadherin

Background: Despite the well-documented association between loss of E-cadherin and carcinogenesis, as well as the link between restoration of its expression and suppression of proliferation in carcinoma cells, the ability of E-cadherin to modulate growth-promoting cell signalling in normal epithelial cells is less well understood and frequently contradictory. The potential for E-cadherin to co-ordinate different proliferation-associated signalling pathways has yet to be fully explored. Methodology/Principal Findings: Using a normal human urothelial (NHU) cell culture system and following a calcium-switch approach, we demonstrate that the stability of NHU cell-cell contacts differentially regulates the Epidermal Growth Factor Receptor (EGFR)/Extracellular Signal-Regulated Kinase (ERK) and Phosphatidylinositol 3-Kinase (PI3-K)/AKT pathways. We show that stable cell contacts down-modulate the EGFR/ERK pathway, whilst inducing PI3-K/AKT activity, which transiently enhances cell growth at low density. Functional inactivation of E-cadherin interferes with the capacity of NHU cells to form stable calcium-mediated contacts, attenuates E-cadherin-mediated PI3-K/AKT induction and enhances NHU cell proliferation by allowing de-repression of the EGFR/ERK pathway and constitutive activation of beta-catenin-TCF signalling. Conclusions/Significance: Our findings provide evidence that E-cadherin can differentially and concurrently regulate specific growth-related signalling pathways in a context-specific fashion, with direct, functional consequences for cell proliferation and population growth. Our observations not only reveal a novel, complex role for E-cadherin in normal epithelial cell homeostasis and tissue regeneration, but also provide the basis for a more complete understanding of the consequences of E-cadherin loss on malignant transformation

Evidence for biquadratic exchange in the quasi-two-dimensional antiferromagnet FePS3_3

FePS$_3$ is a van der Waals compound with a honeycomb lattice that is a good example of a two-dimensional antiferromagnet with Ising-like anisotropy. Neutron spectroscopy data from FePS3 were previously analysed using a straight-forward Heisenberg Hamiltonian with a single-ion anisotropy. The analysis captured most of the elements of the data, however some significant discrepancies remained. The discrepancies were most obvious at the Brillouin zone boundaries. The data are subsequently reanalysed allowing for unequal exchange between nominally equivalent nearest-neighbours, which resolves the discrepancies. The source of the unequal exchange is attributed to a biquadratic exchange term in the Hamiltonian which most probably arises from a strong magnetolattice coupling. The new parameters show that there are features consistent with Dirac magnon nodal lines along certain Brillouin zone boundaries.Comment: 8 pages, 4 figures. The following article has been accepted by the Journal of Applied Physics. After it is published, it will be found at (https://publishing.aip.org/resources/librarians/products/journals/). The article was submitted as part of a special topic edition (https://publishing.aip.org/publications/journals/special-topics/jap/2d-quantum-materials-magnetism-and-superconductivity/

A Completely Invariant SUSY Transform of Supersymmetric QED

We study the SUSY breaking of the covariant gauge-fixing term in SUSY QED and observe that this corresponds to a breaking of the Lorentz gauge condition by SUSY. Reasoning by analogy with SUSY's violation of the Wess-Zumino gauge, we argue that the SUSY transformation, already modified to preserve Wess-Zumino gauge, should be further modified by another gauge transformation which restores the Lorentz gauge condition. We derive this modification and use the resulting transformation to derive a Ward identitiy relating the photon and photino propagators without using ghost fields. Our transformation also fulfills the SUSY algebra, modulo terms that vanish in Lorentz gauge

Feasibility, parametric design, and comparative analysis of an unguided solid fuel rocket vehicle with solar orbit, earth probe, and re-entry mission capabilities

Feasibility, parametric design, and comparative analysis of unguided solid fuel rocket vehicle with solar orbit, earth probe, and reentry mission capabilitie

Role of Spontaneous Emission in Ultracold Two-Color Optical Collisions

We have observed violet photon emission resulting from energy-pooling collisions between ultracold Rb atoms illuminated by two colors of near-resonant infrared laser light. We have used this emission as a probe of doubly excited state ultracold collision dynamics. By varying the detuning of the lasers, we have clearly identified the effect of spontaneous emission on the collision process