Architecting Write-Back Caches and Scatter/Gather I/O

In recent years, much research has been de- voted to the exploration of interrupts; nevertheless, few have explored the study of courseware. Such a claim is usually a practical ambition but is supported by related work in the field. After years of technical research into the transistor, we prove the simulation of simulated annealing, demonstrates the confusing importance of artificial intelligence. In our research, we understand how DNS can be applied to the construction of the UNIVAC computer. This at first glance seems unexpected but is derived from known re- sults

Propagation and amplification of tide at the northeastern coast of the Antarctic peninsula: an observational study

The amplification and propagation of the tide at the northeastern coast of the Antarctic Peninsula was studied by analysis of instantaneous sea levels measured at the tidal station of Base Esperanza,at the northern end of the Antarctic Peninsula (63゜22.46\u27S, 56゜59.33\u27W) ,at the northeastern coast of Marambio Island (Seymour Island,64゜14.11\u27S, 56゜34.51\u27W) and near Base Matienzo,Larsen nunatak (64゜54.23\u27S, 60゜2.60\u27W) at the edge of the Larsen ice-shelf. By means of harmonic analysis the amplitudes and phases of the most energetic ten tidal constituents were obtained.The tidal regime was typified by means of the factor F and a preponderantly semidiurnal mixed tide was obtained. Signi ficant southward amplification was observed in the amplitudes of semidiurnal constituents,and a less evident amplification was obtained in diurnal ones.Consequently,slightly southward diminution in factor F,from 0.75 (Esperanza) to 0.6 (Matienzo),was found.Bothsouthward amplification in amplitudes and northward propagation of the main tidal constituents obtained from numerical global models show good agreement with the present observations

Relationships between technical efficiency and the quality and costs of health care in Italy†

Objectives This paper reports the measurement of technical efficiency of Tuscan Local Health Authorities and its relationship with quality and appropriateness of care. Design First, a bias-corrected measure of technical efficiency was developed using the bootstrap technique applied to data envelopment analysis. Then, correlation analysis was used to investigate the relationships among technical efficiency, quality and appropriateness of care. Setting and Participants These analyses have been applied to the Local Health Authorities of Tuscany Region (Italy), which provide not only hospital inpatient services, but also prevention and primary care. All top managers of Tuscan Local Health Authorities were involved in selection of the inputs and outputs for calculating technical efficiency. Main Outcome Measures The main measures used in this study are volume, quality and appropriateness indicators monitored by the multidimensional performance evaluation system developed in the Tuscany Region. Results On average, Tuscan Local Health Authorities experienced 14(%) of bias-corrected inefficiency in 2007. Correlation analyses showed a significant negative correlation between per capita costs and overall performance. No correlation was found in 2007 between technical efficiency and overall performance or between technical efficiency and per capita costs. Conclusions Technical efficiency cannot be considered as an extensive measure of healthcare performance, but evidence shows that Tuscan Local Health Authorities have room for improvement in productivity levels. Indeed, correlation findings suggest that, to pursue financial sustainability, Local Health Authorities mainly have to improve their performance in terms of quality and appropriateness

A numerical study of the ocean circulation around the northern Antarctic Peninsula: Barotropic response to tidal forcing

A high-resolution shallow water model was implemented to study tidal propagation around the northern Antarctic Peninsula. Numerical experiments were done using a grid with 3.00′longitude and 1.05′latitude resolution. Amplitudes and phases of the four main tidal constituents (M_2, S_2, K_1 and O_1) were used to force the model. Modeled sea levels and currents were compared with observations. The modeled cotidal, corange and tidal ellipse axis obtained by harmonic analysis from model results are in good agreement with those of available observations. Given the good correspondence between harmonic constants obtained from model results and from observed hourly sea levels, the energy flux and dissipation by bottom friction were computed. The most intense energy fluxes are related to the semidiurnal constituents. The highest values are present in the Weddell Sea and the energy flux shows a relative maximum at the Antarctic Strait, flowing from the Weddell Sea to Bransfield Strait. Nearly all the dissipation occurs in the Antarctic Strait (maximum value ～0.25Wm^(-2)) and around the South Shetland Islands. The total tidal energy lost to bottom friction in our 4-constituent model is about 1.5GW, giving a domain-averaged value of ～0.002Wm^(-2)

Aplicación de osteotécnicas no invasivas en la preparación del esqueleto del Macá Grande (Podicpeos major major)

Fil: Porcari, C. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas, Físicas y Naturales; Argentina.Fil: Carabajal Vera, M. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas, Físicas y Naturales; Argentina.Fil: Bulfon, M. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas, Físicas y Naturales; Argentina.Fil: Bee de Speroni, N. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas, Físicas y Naturales; Argentina.La preparación y exhibición de piezas esqueléticas de diferentes vertebrados adquieren importancia en disciplinas científicas y representan un excelente recurso didáctico en los diferentes niveles educativos.Fil: Porcari, C. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas, Físicas y Naturales; Argentina.Fil: Carabajal Vera, M. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas, Físicas y Naturales; Argentina.Fil: Bulfon, M. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas, Físicas y Naturales; Argentina.Fil: Bee de Speroni, N. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas, Físicas y Naturales; Argentina.Zoología, Ornitología, Entomología, Etologí

From single cells to tissues: interactions between the matrix and human breast cells in real time.

International audienceMammary gland morphogenesis involves ductal elongation, branching, and budding. All of these processes are mediated by stroma--epithelium interactions. Biomechanical factors, such as matrix stiffness, have been established as important factors in these interactions. For example, epithelial cells fail to form normal acinar structures in vitro in 3D gels that exceed the stiffness of a normal mammary gland. Additionally, heterogeneity in the spatial distribution of acini and ducts within individual collagen gels suggests that local organization of the matrix may guide morphogenesis. Here, we quantified the effects of both bulk material stiffness and local collagen fiber arrangement on epithelial morphogenesis. The formation of ducts and acini from single cells and the reorganization of the collagen fiber network were quantified using time-lapse confocal microscopy. MCF10A cells organized the surrounding collagen fibers during the first twelve hours after seeding. Collagen fiber density and alignment relative to the epithelial surface significantly increased within the first twelve hours and were a major influence in the shaping of the mammary epithelium. The addition of Matrigel to the collagen fiber network impaired cell-mediated reorganization of the matrix and increased the probability of spheroidal acini rather than branching ducts. The mechanical anisotropy created by regions of highly aligned collagen fibers facilitated elongation and branching, which was significantly correlated with fiber organization. In contrast, changes in bulk stiffness were not a strong predictor of this epithelial morphology. Localized regions of collagen fiber alignment are required for ductal elongation and branching suggesting the importance of local mechanical anisotropy in mammary epithelial morphogenesis. Similar principles may govern the morphology of branching and budding in other tissues and organs

Parental Perceptions of the Rural School’s Role in Addressing Childhood Obesity

This study employed cross-sectional, descriptive design with convenience sampling to explore rural parent perceptions of child obesity, use of Body Mass Index (BMI) in schools, preferences for receipt of BMI information and, the rural school’s role in obesity prevention/treatment. The survey “Parental Perceptions of BMI and Obesity in the School-Age Child” was used. Of the 183 surveys distributed, 65 were returned (35.5%). Fifty-five percentage of parents were in agreement of school-based BMI screening. Fifty-four percentage of parents selected a combination of ways to receive BMI information (letter from school nurse, face-to-face conference with nurse, or via report card). Few parents (6.2%) were reluctant to schools addressing obesity. Significant relationships were identified between non-White, overweight parents who had overweight children (n = 3). They were more likely to disagree with removal of junk food, increasing physical activity, and recommending weight loss. Recommendations to involve parents in BMI screening are presented

Estudio de la marea en el borde de la barrera Larsen, Mar de Weddell noroccidental

El objetivo de este trabajo es el estudio de la marea en el borde de la barrera Larsen (latitud: 64° 54' 14" S, longitud: 60° 02' 36" W) en el mar de Weddell noroccidental, Antártida. Los niveles del mar se registraron con un sensor de presión y mediante nivelación geométrica (mira y nivel). El coeficiente de determinación de los niveles del mar obtenidos con ambas técnicas es de 0.96. Se presentan las constantes armónicas de las componentes de marea más energéticas. Se realiza un análisis comparativo entre las constantes calculadas y las que surgen de modelos mareológicos globales y se discute la propagación de la marea en el mar de Weddell noroccidental. Se tipificó el régimen de marea cuantitativamente mediante el coeficiente de Courtier resultando un régimen mixto preponderantemente semidiurno. Los niveles del mar registrados en esta zona de la Antártida son inéditos debido a que el sitio de mediciones fue inaccesible durante muchos años.The objective of this paper is the study of the tide at the Larsen iceshelf boundary (latitude: 64° 54' 14" S, longitude: 60° 02' 36" W), Northwestern Weddell Sea, Antarctica. Sea levels were recorded using pressure sensor and geometric leveling (sight and level). The determination coefficient from sea level gathered with both methods is 0.96. Harmonic constants of the most energetic tidal constituents are presented. A comparative analysis between calculated harmonic constants and those obtained from tidal global models is made and tidal propagation in the Northwestern Weddell Sea is discussed. Tidal regimen is quantified by means of the Courtier coefficient and a preponderantly semidiurnal mixed tide is obtained. Sea levels gathered in this zone of the Antarctica are completely new because the place where the measurements were made was inaccessible for a large period of years.Asociación Argentina de Geofísicos y Geodesta

Estudio de la marea en el borde de la barrera Larsen, Mar de Weddell noroccidental

El objetivo de este trabajo es el estudio de la marea en el borde de la barrera Larsen (latitud: 64° 54' 14" S, longitud: 60° 02' 36" W) en el mar de Weddell noroccidental, Antártida. Los niveles del mar se registraron con un sensor de presión y mediante nivelación geométrica (mira y nivel). El coeficiente de determinación de los niveles del mar obtenidos con ambas técnicas es de 0.96. Se presentan las constantes armónicas de las componentes de marea más energéticas. Se realiza un análisis comparativo entre las constantes calculadas y las que surgen de modelos mareológicos globales y se discute la propagación de la marea en el mar de Weddell noroccidental. Se tipificó el régimen de marea cuantitativamente mediante el coeficiente de Courtier resultando un régimen mixto preponderantemente semidiurno. Los niveles del mar registrados en esta zona de la Antártida son inéditos debido a que el sitio de mediciones fue inaccesible durante muchos años.The objective of this paper is the study of the tide at the Larsen iceshelf boundary (latitude: 64° 54' 14" S, longitude: 60° 02' 36" W), Northwestern Weddell Sea, Antarctica. Sea levels were recorded using pressure sensor and geometric leveling (sight and level). The determination coefficient from sea level gathered with both methods is 0.96. Harmonic constants of the most energetic tidal constituents are presented. A comparative analysis between calculated harmonic constants and those obtained from tidal global models is made and tidal propagation in the Northwestern Weddell Sea is discussed. Tidal regimen is quantified by means of the Courtier coefficient and a preponderantly semidiurnal mixed tide is obtained. Sea levels gathered in this zone of the Antarctica are completely new because the place where the measurements were made was inaccessible for a large period of years.Asociación Argentina de Geofísicos y Geodesta