Reef response to sea-level and environmental changes during the last deglaciation: Integrated Ocean Drilling Program Expedition 310, Tahiti Sea Level

The last deglaciation is characterized by a rapid sea-level rise and coeval abrupt environmental changes. The Barbados coral reef record suggests that this period has been punctuated by two brief intervals of accelerated melting (meltwater pulses, MWP), occurring at 14.08-13.61 ka and 11.4-11.1 ka (calendar years before present), that are superimposed on a smooth and continuous rise of sea level. Although their timing, magnitude, and even existence have been debated, those catastrophic sea-level rises are thought to have induced distinct reef drowning events. The reef response to sea-level and environmental changes during the last deglacial sea-level rise at Tahiti is reconstructed based on a chronological, sedimentological, and paleobiological study of cores drilled through the relict reef features on the modern forereef slopes during the Integrated Ocean Drilling Program Expedition 310, complemented by results on previous cores drilled through the Papeete reef. Reefs accreted continuously between 16 and 10 ka, mostly through aggradational processes, at growth rates averaging 10 mm yr-1. No cessation of reef growth, even temporary, has been evidenced during this period at Tahiti. Changes in the composition of coralgal assemblages coincide with abrupt variations in reef growth rates and characterize the response of the upward-growing reef pile to nonmonotonous sea-level rise and coeval environmental changes. The sea-level jump during MWP 1A, 16 ± 2 m of magnitude in ~350 yr, induced the retrogradation of shallow-water coral assemblages, gradual deepening, and incipient reef drowning. The Tahiti reef record does not support the occurrence of an abrupt reef drowning event coinciding with a sea-level pulse of ~15 m, and implies an apparent rise of 40 mm yr-1 during the time interval corresponding to MWP 1B at Barbados. © 2012 Geological Society of America

Therapeutic lung lavages in children and adults

BACKGROUND: Pulmonary alveolar proteinosis (PAP) is a rare disease, characterized by excessive intra-alveolar accumulation of surfactant lipids and proteins. Therapeutic whole lung lavages are currently the principle therapeutic option in adults. Not much is known on the kinetics of the wash out process, especially in children. METHODS: In 4 pediatric and 6 adult PAP patients 45 therapeutic half lung lavages were investigated retrospectively. Total protein, protein concentration and, in one child with a surfactant protein C mutation, aberrant pro-SP-C protein, were determined during wash out. RESULTS: The removal of protein from the lungs followed an exponential decline and averaged for adult patients 2 – 20 g and <0.5 to 6 g for pediatric patients. The average protein concentration of consecutive portions was the same in all patient groups, however was elevated in pediatric patients when expressed per body weight. The amount of an aberrant pro-SP-C protein, which was present in one patient with a SP-C mutation, constantly decreased with ongoing lavage. Measuring the optical density of the lavage fluid obtained allowed to monitor the wash out process during the lavages at the bedside and to determine the termination of the lavage procedure at normal protein concentration. CONCLUSION: Following therapeutic half lung lavages by biochemical variables may help to estimate the degree of alveolar filling with proteinaceous material and to improve the efficiency of the wash out, especially in children

New tools and approaches in carbonate reservoir quality prediction: A case history from the Shu'aiba Formation, Saudi Arabia

Reservoir quality prediction has historically been the 'holy grail' of reservoir geologists, yet few have succeeded at achieving this in a quantitative fashion. This study presents a new approach to pre-drill reservoir quality prediction that involves the integration of a variety of modelling techniques to understand, quantify and predict the geological processes that control reservoir quality. Since the initial reservoir quality framework is established at the time of deposition by a variety of depositional controls, this approach uses numerical process models to predict initial reservoir quality; results from these depositional models are then modified via a series of process modelling technologies to quantify and predict post-depositional modifications that have significantly affected reservoir quality in the interval of interest. This approach is illustrated using an example from the Early Cretaceous Shu'aiba Formation in eastern Saudi Arabia, where depositional facies, diagenesis and resulting reservoir quality are predicted and tested against well and seismic data, with generally positive results. Model-predicted sediment thicknesses match thicknesses measured in wells to within ±0.5%; depositional facies and diagenetic trends seen in key wells from the Shaybah field matched model-predicted facies and diagenesis; and model-predicted porosity matched observed porosity within ±1.8 porosity units