Pengaruh Suplementasi Betain terhadap Beberapa Parameter Lipida dan Protein Darah pada Puyuh

The objective of this research was to see the influence of betaine supplementation on some of blood lipid and protein parameters in laying quails. The research used four treatments based on completely randomized design. Each treatment was replicated five times with seventeen quails each. The treatments used 340 quails aged 4 weeks with average weigh 98.31±8.67 grams. The supplementation levels of betaine were 0 (control); 0.07; 0.14 and 0.21%. Twenty quails aged 14 weeks were taken from each replicate to determine blood lipid and protein. Data were analyzed by analysis of variance and if there was an effect of treatment, then it was analyzed by Duncan’s Multiple Range Test. The result showed that betaine supplementation at level 0.14% resulted higher level of low density lipoprotein compared with the other treatments. It could be concluded that betaine supplementation at 0.14% resulted higher concentration of low density lipoprotein than control. Key words: quail, betaine, blood lipid, blood protei

The presence of Plasmodium malariae and Plasmodium knowlesi in near malaria elimination setting in western Indonesia

Background Indonesia is progressing towards malaria elimination. To achieve this goal, intervention measures must be addressed to cover all Plasmodium species. Comprehensive control measures and surveillance programmes must be intensified. This study aims to determine the prevalence of microscopic and submicroscopic malaria in Langkat district, North Sumatera Province, Indonesia. Methods A cross-sectional survey was conducted in six villages in Langkat district, North Sumatera Province in June 2019. Data were recorded using a standardized questionnaire. Finger pricked blood samples were obtained for malaria examination using rapid diagnostic test, thick and thin blood smears, and polymerase chain reaction. Results A total of 342 individuals were included in the study. Of them, one (0.3%) had a microscopic Plasmodium malariae infection, no positive RDT examination, and three (0.9%) were positive for P. malariae (n = 1) and Plasmodium knowlesi (n = 2). The distribution of bed net ownership was owned by 40% of the study participants. The participants had a house within a radius of 100–500 m from the forest (86.3%) and had the housing material of cement floor (56.1%), a tin roof (82.2%), wooden wall (35.7%), bamboo wall (28.1%), and brick wall (21.6%). Conclusion Malaria incidence has substantially decreased in Langkat, North Sumatera, Indonesia. However, submicroscopic infection remains in the population and may contribute to further transmission. Surveillance should include the detection of microscopic undetected parasites, to enable the achievement of malaria elimination

Evaluasi Sistem Penyimpanan Obat Berdasarkan Standar Pelayanan Kefarmasian di Apotek M Manado

Penelitian ini bertujuan Untuk mengevaluasi  sistem penyimpanan Obat di apotek M Manado berdasarkan petunjuk teknis standar kefarmasian di apotik tahun 2019. Penelitian ini merupakan penelitian observasional yang bersifat deskriptif, yang bertujuan untuk melihat sistem penyimpanan obat di Apotek M  Berdasarkan hasil penelitian yang telah dilakukan dapat disimpulkan bahwa penyimpanan obat di Apotek M Manado  belum sepenuhnya sesuai dengan Petunjuk Teknis Standar Pelayanan Kefarmasian di Apotek tahun 2019,dapat dilihat dari hasil persentase sebesar 69,57% yang sesuai . Salah satunya dapat dilihat dari penyimpanan obat LASA/NORUM yang tidak sesuai,walaupun obat terletak dalam kelompok abjad yang sama harus diselingi dengan minimal dua obat dengan kategori LASA/NORUM diantara atau tengahnya .Banyaknya nama obat membuat medication error  didasarkan pada penampilan yang mirip atau suara ketika ditulis atau diucapkan atau juga telah diidentifikasi memiliki potensi yang membingungkan

UJI EFEK ANTIHISTAMINERGIK DARI TANAMAN ANDROGRAPHIS PANICULATA NEES

Telah dilakukan pengujian efek antihistaminergik dari tanaman Andrographis paniculata Nees dengan melihat hambatan kontraksi ileum marmot terisolasi yang diinduksi dengan histamin dihidroksiklorida. Fraksi etanol dari tanaman Andrographis paniculata Nees dapat menghambat kontraksi ileum marmot terisolasi yang diinduksi dengan histamin dihidroksiklorida (p< 0,05)