The Passive Optical Sample Assembly (POSA) on STS-1

The passive optical sample assembly (POSA) hardware, scheduled for the flight on orbital flight test 1 is described. The function of the instrument is aid in the assessment contamination hazards to sensitive payloads in the shuttle cargo bay. It consists of an array of passively deployed samples mounted on the development flight instrumentation pallet in the shuttle cargo bay. The directory of samples together with their intended measurements are presented. The plan for POSA data analysis is also given

Second LDEF Post-Retrieval Symposium interim results of experiment A0034

Thermal control coatings and contaminant collector mirrors were exposed on the leading and trailing edge modules of Long Duration Exposure Facility (LDEF) experiment A0034 to provide a basis of comparison for investigating the role of atomic oxygen in the stimulation of volatile outgassing products. The exposure of identical thermal coatings on both the leading and trailing edges of the LDEF and the additional modified exposure of identical coatings under glass windows and metallic covers in each of the flight modules provided multiple combinations of space environmental exposure to the coatings and the contaminant collector mirrors. Investigations were made to evaluate the effects of the natural space and the induced environments on the thermal coatings and the collector mirrors to differentiate the sources of observed material degradation. Two identical flight units were fabricated for the LDEF mission, each of which included twenty-five thermal control coatings mounted in isolated compartments, each with an adjacent contaminant collector mirror mounted on the wall. The covers of the flight units included apertures for each compartment, exposing the thermal coatings directly to the space environment. Six of these compartments were sealed with ultraviolet-grade transmitting quartz windows and four other compartments were sealed with aluminum covers. One module of this passive LDEF experiment, occupying one-sixth of a full tray, was mounted in Tray C9 (leading edge), while the other identical module was mounted in Tray C3 (trailing edge)

Passive Optical Sample Assembly (POSA) for STS-1 quick look post-mission report

A passively deployed array of contamination-sensitive samples was mounted and flown in the cargo bay of the space shuttle Columbia during the first orbital flight test. A similar unit was mounted in a different location in the cargo bay at Dryden Flight Research Center during the postflight operations there prior to the ferry flight return of Columbia to Kennedy Space Center. The samples in both POSA arrays were subjected to a series of optical and analytical measurements prior to delivery for installation in the cargo bay and after retrieval of the flight hardware. A quick-look summary of the results of a comparison of the series of measurements is presented

Identifying long cycles in finite alternating and symmetric groups acting on subsets

Let $H$ be a permutation group on a set $\Lambda$, which is permutationally isomorphic to a finite alternating or symmetric group $A_n$ or $S_n$ acting on the $k$-element subsets of points from $\{1,\ldots,n\}$, for some arbitrary but fixed $k$. Suppose moreover that no isomorphism with this action is known. We show that key elements of $H$ needed to construct such an isomorphism $\varphi$, such as those whose image under $\varphi$ is an $n$-cycle or $(n-1)$-cycle, can be recognised with high probability by the lengths of just four of their cycles in $\Lambda$.Comment: 45 page

Estimating Yield Curves by Kernel Smoothing Methods

We introduce a new method for the estimation of discount functions, yield curves and forward curves for coupon bonds. Our approach is nonparametric and does not assume a particular functional form for the discount function although we do show how to impose various important restrictions in the estimation. Our method is based on kernel smoothing and is defined as the minimum of some localized population moment condition. The solution to the sample problem is not explicit and our estimation procedure is iterative, rather like the backfitting method of estimating additive nonparametric models. We establish the asymptotic normality of our methods using the asymptotic representation of our estimator as an infinite series with declining coefficients. The rate of convergence is standard for one dimensional nonparametric regression.Coupon bonds; forward curve; Hilbert space; local linear; nonparametric regression; yield curve

Passive Optical Sample Assembly (POSA)

A Passive Optical Sample Assembly (POSA) unit was mounted and flown in the cargo bay of the space shuttle Columbia during the first Orbital Flight Test (OFT-1). A similar unit was mounted in a different location in the cargo bay during the postflight operations. The samples in both POSA arrays were subjected to a series of optical and analytical measurements prior to delivery for installation in the cargo bay and after retrieval of the flight hardware. The final results of a comparison of the two series of measurements are presented. These STS-1 results are based on data obtained from only a portion of one of the ten Induced Environment Contamination Monitor instruments to be flown on several shuttle flights beginning with STS-2. These limited results do not indicate shuttle contamination levels in excess of those anticipated

A Simple and Effective Method of Detecting Trichina in Sausage

Trichinosis is not a common disease in the United States on account of present day methods of handling meats and the rather universal habit of eating meat only after being well cooked. Occasionally, however, we find people partaking of raw or poorly cooked sausage. An outbreak of the disease resulting from the eating of raw summer sausage and involving five or six families and ten or more individuals occurred at Bridgewater, Iowa, last February. Several of the cases proved fatal

Yield Curve Estimation by Kernel Smoothing Methods

We introduce a new method for the estimation of discount functions, yield curves and forward curves from government issued coupon bonds. Our approach is nonparametric and does not assume a particular functional form for the discount function although we do show how to impose various restrictions in the estimation. Our method is based on kernel smoothing and is defined as the minimum of some localized population moment condition. The solution to the sample problem is not explicit and our estimation procedure is iterative, rather like the backfitting method of estimating additive nonparametric models. We establish the asymptotic normality of our methods using the asymptotic representation of our estimator as an infinite series with declining coefficients. The rate of convergence is standard for one dimensional nonparametric regression. We investigate the finite sample performance of our method, in comparison with other well-established methods, in a small simulation experiment.Coupon bonds, kernel estimation, Hilbert space, nonparametric regression, term structure estimation, yield curve, zero coupon.

Early activation of peripheral monocytes with hallmarks of M1 and M2 monocytic cells in excessive alcohol drinkers: a pilot study

Excessive drinking can lead to the development of immune dysfunction. Our aim is to investigate the effect of alcohol on immune activation from circulating peripheral blood monocytes in excessive drinkers (EDs). Twenty-two EDs and healthy controls were enrolled. Time line follow-back was used to quantify the amount of alcohol consumed in the past 30 days before enrollment. Peripheral blood-derived CD14+ monocytes were isolated for gene expression analyses. Serum interleukin (IL)-6, IL-10 and lipopolysaccharides (LPS) were also measured. We found that serum LPS concentrations were significantly higher in EDs compared with controls (P<0.05). While no differences in the levels of circulating IL-6 and IL-10 were observed, the relative levels of gene transcripts (RQ) for Il6 (an M1-polarizing cytokine) and Il10 (an M2-polarizing cytokine) were significantly higher in peripheral blood-derived monocytes from EDs compared with controls (Il6: P<0.01. Il10: P<0.05). EDs exhibit early immune activation of peripheral blood monocyte mRNA transcripts, notably Il6 and Il10 Future studies are needed to explore the clinical implications of our findings and determine whether the levels of Il6 and Il10 mRNA expression can be used to identify those with excessive drinking and to monitor for alcohol abstinence