Covalent immobilization of bovine serum albumin onto (maleic anhydride-alt-methyl vinyl ether) copolymers

International audienc

Block Copolymers of Poly(2-oxazoline)s and Poly(meth)acrylates: A Crossover between Cationic Ring-Opening Polymerization (CROP) and Reversible Addition–Fragmentation Chain Transfer (RAFT)

To combine the advantages of poly(2-oxazoline)s (POx) and controlled radical polymerization (CRP) techniques, the cationic ring-opening polymerization (CROP) of 2-methyl-2-oxazoline (MeOx), 2-ethyl-2-oxazoline (EtOx), and 2-n-nonyl-2-oxazoline (NonOx) were terminated with a carboxylic acid functionalized chain transfer agent (CTA). The obtained PEtOx with a high degree of functionalization (DF) was used as macro-CTA for the reversible addition–fragmentation chain transfer (RAFT) polymerization of various vinylic monomers (styrene (St), methyl acrylate (MA), tert-butyl acrylate (tBuA), acrylic acid (AA), N,N-dimethyl acrylamide (DMAAm), and N,N-dimethylaminoethylacrylate (DMAEA)) resulting in well-defined block copolymers. Thus, in this work we report a versatile route to combine poly(2-oxazoline)s prepared via CROP with RAFT polymerization for the synthesis of novel block copolymers

Hybrid polymer/lipid vesicles: state of the art and future perspectives

Hybrid vesicles resulting from the combined self-assembly of both amphiphilic copolymers and lipids have attracted particular interest from chemists and (bio)physicists over the last five years. Such assemblies may be viewed as an advanced vesicular structure compared to their liposome and polymersome forerunners as the best characteristics from the two different systems can be integrated in a new, single vesicle. To afford such a design, the different parameters controlling both self-assembly and membrane structure must be tuned. This highlight aims to present a comprehensive overview of the fundamental aspects related to these structures, and discuss emerging developments and future applications in this field of research