Continuous volumetric imaging via an optical phase-locked ultrasound lens

In vivo imaging at high spatiotemporal resolution is key to the understanding of complex biological systems. We integrated an optical phase-locked ultrasound lens into a two-photon fluorescence microscope and achieved microsecond-scale axial scanning, thus enabling volumetric imaging at tens of hertz. We applied this system to multicolor volumetric imaging of processes sensitive to motion artifacts, including calcium dynamics in behaving mouse brain and transient morphology changes and trafficking of immune cells

Advanced turboprop testbed systems study. Volume 1: Testbed program objectives and priorities, drive system and aircraft design studies, evaluation and recommendations and wind tunnel test plans

The establishment of propfan technology readiness was determined and candidate drive systems for propfan application were identified. Candidate testbed aircraft were investigated for testbed aircraft suitability and four aircraft selected as possible propfan testbed vehicles. An evaluation of the four candidates was performed and the Boeing KC-135A and the Gulfstream American Gulfstream II recommended as the most suitable aircraft for test application. Conceptual designs of the two recommended aircraft were performed and cost and schedule data for the entire testbed program were generated. The program total cost was estimated and a wind tunnel program cost and schedule is generated in support of the testbed program

Observational evidence of the formation of cyanopolyynes in CRL618 through the polimerization of HCN

The abundance ratio of consecutive members of the cyanopolyynes family has been explored in CRL618 using data acquired in a complete line survey covering the frequency range 81-356 GHz. The Jup range explored for the different molecules is the following: 1 to 4 for HCN and HNC, 9 to 39 for HC3N, 31 to 133 for HC5N, and 72 to 85 for HC7N (not detected beyond Jup=85). The lowest vibrationally excited state of HC7N (nu_15 at 62 cm^-1) has been tentatively detected. Data analysis has been performed by extending our previous geometrical and radiative transfer model of the slowly expanding envelope (SEE) surrounding the compact central continuum source of CRL 618, that was established from the study of rotational lines in several vibrationally excited states of HC_3N. The new lines analyzed here require to model the high velocity wind (HVW) component and the colder circumstellar gas, remnant of the AGB phase of CRL618. The derived HC3N/HC5N and HC5N/HC7N abundance ratios from this set of uniformly calibrated lines are between 3 and 6 in the different regions, similar to standard values in the CSM and ISM, and consistent with previous estimates obtained from ISO observations and chemical models. However, the abundance ratios of HC3N, HC5N and HC7N with respect to HCN are at least two orders of magnitude larger than those typical for AGB C-rich stars, such as IRC+10216. This fact indicates that, in the short transition toward the Planetary Nebula phase, HCN is quickly reprocessed into longer cyanopolyyne chains. A similar behavior was previously found in this object for the polyacetylenic chains (C(2n)H2).Comment: 8 figures, accepted in ApJ main journa

Navigation input to level C OFT navigation functional subsystem software requirements (rendezvous onorbit-2)

Navigation software design requirements are presented for the orbital flight test phase of space shuttle. Computer loads for the entire onorbit-2 operation are documented

7-Li(p,n) Nuclear Data Library for Incident Proton Energies to 150 MeV

We describe evaluation methods that make use of experimental data, and nuclear model calculations, to develop an ENDF-formatted data library for the reaction p + Li7 for incident protons with energies up to 150 MeV. The important 7-Li(p,n_0) and 7-Li(p,n_1) reactions are evaluated from the experimental data, with their angular distributions represented using Lengendre polynomial expansions. The decay of the remaining reaction flux is estimated from GNASH nuclear model calculations. The evaluated ENDF-data are described in detail, and illustrated in numerous figures. We also illustrate the use of these data in a representative application by a radiation transport simulation with the code MCNPX.Comment: 11 pages, 8 figures, LaTeX, submitted to Proc. 2000 ANS/ENS International Meeting, Nuclear Applications of Accelerator Technology (AccApp00), November 12-16, Washington, DC, US

Objective automatic assessment of rehabilitative speech treatment in Parkinson's disease

Vocal performance degradation is a common symptom for the vast majority of Parkinson's disease (PD) subjects, who typically follow personalized one-to-one periodic rehabilitation meetings with speech experts over a long-term period. Recently, a novel computer program called Lee Silverman voice treatment (LSVT) Companion was developed to allow PD subjects to independently progress through a rehabilitative treatment session. This study is part of the assessment of the LSVT Companion, aiming to investigate the potential of using sustained vowel phonations towards objectively and automatically replicating the speech experts' assessments of PD subjects' voices as “acceptable” (a clinician would allow persisting during in-person rehabilitation treatment) or “unacceptable” (a clinician would not allow persisting during in-person rehabilitation treatment). We characterize each of the 156 sustained vowel /a/ phonations with 309 dysphonia measures, select a parsimonious subset using a robust feature selection algorithm, and automatically distinguish the two cohorts (acceptable versus unacceptable) with about 90% overall accuracy. Moreover, we illustrate the potential of the proposed methodology as a probabilistic decision support tool to speech experts to assess a phonation as “acceptable” or “unacceptable.” We envisage the findings of this study being a first step towards improving the effectiveness of an automated rehabilitative speech assessment tool

The measurement of low pay in the UK labour force survey

Consideration of the National Minimum Wage requires estimates of the distribution of hourly pay. The UK Labour Force Survey (LFS) is a key source of such estimates. The approach most frequently adopted by researchers has been to measure hourly earnings from several questions on pay and hours. The Office for National Statistics is now applying a new approach, based on an alternative more direct measurement introduced in March 1999. These two measures do not produce identical values and this paper investigates sources of discrepancies and concludes that the new variable is more accurate. The difficulty with using the new variable is that it is only available on a subset of respondents. An approach is developed in which missing values of the new variable are replaced by imputed values. The assumptions underlying this imputation approach and results of applying it to LFS data are presented. The relation to weighting approaches is also discussed

The Initial Configuration of Young Stellar Clusters: A K-band Number Counts Analysis of the Surface Density of Stars

We present an analysis of K-band stellar distributions for the young stellar clusters GGD 12-15, IRAS 20050+2720, and NGC 7129. We find that the two deeply embedded clusters, GGD 12-15 and IRAS 20050+2720, are not azimuthally symmetric and show a high degree of structure which traces filamentary structure observed in 850 micron emission maps. In contrast, the NGC 7129 cluster is circularly symmetric, less dense, and anti-correlated to 850 micron emission, suggesting recent gas expulsion and dynamical expansion have occured. We estimate stellar volume densities from nearest neighbor distances, and discuss the impact of these densities on the evolution of circumstellar disks and protostellar envelopes in these regions.Comment: 44 pages, 26 figures, Accepted to ApJ. Changes include extinction mapping, Monte Carlo field star modeling, and Nyquist sampled azimuthal stellar distributions. A version with full resolution figures is available at http://astro.pas.rochester.edu/~rguter/preprints/gutermuth_sd.tar.g

Sex differences in the perceived dominance and prestige of women with and without cosmetics

Women wearing cosmetics have been associated with a higher earning potential and higher status jobs. However, recent literature suggests that status can be accrued through two distinct routes: dominance and prestige. In two experiments, we applied a standardized amount of cosmetics to female faces using computer software. We then asked participants to rate faces with and without cosmetics for various traits including attractiveness, dominance, and prestige. Men and women both rated the faces with cosmetics added as higher in attractiveness. However, only women rated faces with cosmetics as higher in dominance, while only men rated them as higher in prestige. In a follow-up study, we investigated whether these enhanced perceptions of dominance from women were caused by jealousy. We found that women experience more jealousy toward women with cosmetics, and view these women as more attractive to men and more promiscuous. Our findings suggest that cosmetics may function as an extended phenotype and can alter other’s perceptions differently depending on the perceiver’s sex.</p