Lifeview and perception of message in drama

The age-old controversy between church and the arts has not been resolved by a long shot. The ethically repellent in modern art is definitely over-emphasized at the cost of the ethically acceptable. This leads to the question about the Chri­stian response to a play with a non-Christian lifeview, one in which the charac­ters use crude language and in which vulgar actions are indulged in

Corticosteroids in sports-related injuries: Friend or Foe

Corticosteroids act as potent anti-inflammatory drugs and have been used in various sport settings for the treatment of both acute and chronic injuries. Basic physiology and mechanisms of action for gluco- and mineralocorticoids are discussed. Methods of administration, the action on the inflammatory response, and potential short and long-term side effects of corticosteroid use are also deliberated. More specifically, corticosteroid use in the treatment and management of sport-related injuries are discussed, elucidating on the ethical boundaries and anti-doping regulations pertaining to corticosteroid use in sports, as well as putting forth suggestions for the use of local steroid injections and their contraindications. In conclusion, it was found that, despite some controversy in the use of corticosteroid treatment in the sports environment, little empirical evidence exists that could conclusively rule for or against its use. It is however clear that, if clinically justified, there is a significant role for corticosteroid treatment in the realm of sports injury and notably with a relatively low risk profile, if administered correctly.Keywords: Steroid hormones, athlete, sports, injury, inflammation

Sedation with alfentanil and propofol for rhizotomies

Background: Patient safety during sedation for closed rhizotomies is improved when analgesia is optimised, rather than relying on deep sedation for patient comfort. This retrospective study determined the appropriate effect-site concentration (Ce) for alfentanil, in combination with a constant propofol infusion, for optimal pain control during sedation for closed rhizotomies. Airway maintenance is ensured by keeping patients responsive to verbal commands, albeit at the price of inevitable ventilatory depression.Method: The records of patients who received rhizotomies over a six-month period were studied retrospectively. Sixty-three outpatients were included. Patients rated the level of analgesia with each needle placement. If the Ce for alfentanil was adequate, it was kept constant. Otherwise, it was increased in 5 ng/ml increments with each needle placement until analgesia was effective, or up to the maximum Ce for alfentanil of 100 ng/ml. Propofol infusion at a constant Ce of 200 ng/ml was added.Results: Forty-eight per cent of patients reported being comfortable at a Ce for alfentanil of 70–75 ng/ml. Only 5% of patients requested the maximum Ce for alfentanil of 100 ng/ml. All of the patients experienced ventilatory depression, but a patent airway was maintained. The haemodynamic observations were within normal limits. According to the ward records, 16% of the patients complained of nausea, and there was one incident of vomiting.Conclusion: Combining alfentanil at a Ce for alfentanil of 70–100 ng/ml with propofol at 200 ng/ml is a safe and effective method for analgesia during sedation for closed rhizotomies.Keywords: alfentanil, analgesia, procedural sedation, propofol, rhizotomy, target-controlled infusio

The Dhow's last redoubt? Vestiges of wooden boatbuilding traditions in Yemen

This is an accepted version of an article that went on to be published in the Proceedings of the Seminar for Arabian Studies in 2010. The reference for the published version is: Agius, D.A., Cooper, J.P., Jansen van Rensburg, J.and Zazzaro, C., 2010 " The dhow's last redoubt? Vestiges of wooden boatbuilding traditions in Yemen". Proceedings of the Seminar for Arabian Studies 40: 71—84. Please use the published version in any citations.The final version of the article is available from Archaeopress via the link in this record.Researchers from the MARES Project visited Yemen in February 2009 in order to investigate the building and use of traditional wooden boats (‘dhows’, in English parlance) in the country. The survey covered the coastline from Aden to Salif in the Red Sea, and visited centres of traditional dhow building and use, including Ghureira, Mocha and Khokha. The project aimed to assess the state of the industry, establish a vessel typology, understand construction processes, learn about the use of these vessels, and compile a lexicon of boatbuilding and nautical terms. This article offers the preliminary findings of the survey, pending more comprehensive publication in the future. The survey found that, in all locations visited, the building of new vessels had rapidly diminished in the preceding decade, and had now all but ceased. The only ongoing activity witnessed during the survey was repairs to existing wooden craft. In formerly large boat-building centres, wooden boat-builders, mostly elderly, have ceased work, while younger men were building fishing craft using fibreglass – the material used in the great majority of vessels in Yemen today. A preliminary typology of surviving vessel was established. The doubleended cargo-carrying za<īmahs and zārūqs were recorded only as 2 abandoned hulks. Double-ended <obrīs and transom-sterned ‘large hūrīs’, with their stern-quarter ‘fins’, continued to be used in small numbers for sein fishing and transporting livestock. Again, most examples were abandoned. Various forms of small log and plank hūrī ‘canoes’ were observed, few still in use, while the log-raft ramas survives on the Red Sea coast. The terms used for these vessel types form part of a linguistic survey of dhow activity in Yemen.This research was conducted as part of the MARES Project, a three-year programme investigating the maritime past and heritage of the Red Sea and Arabian-Persian Gulf. MARES is based at the Institute of Arab and Islamic Studies at the University of Exeter (http://projects.exeter.ac.uk/mares). The programme is funded by the Golden Web Foundation, an educational charity registered in the UK (www.goldenweb.org), to which our gratitude is due. 27 Thanks are also due to the Seven Pillars of Wisdom Trust, which provided additional financial support for the fieldwork. In addition, the MARES team would like to thank the following people for their assistance: Dr Abdulla M. Bawazir, President of Yemen’s General Organisation of Antiquities and Museums (GOAM); Dr Muhammad Taha al-Asbahi, General Director of Antiquities at GOAM; Dr Raja Batawil, head of GOAM in Aden; our GOAMappointed field companion, Salah al-Mansuri; Mr. Hasan Saleh Shihab; Emily Allardyce, Fuad Mazid al-Matairi and their colleagues at the British Yemeni Language Institute; our driver and guide Muhammad al-Matairi; Edward Prados, Director of Amideast; Chris Evens; the British Council; and the British Embassy. Last but not least, the team wishes to thank the many individual informants along Yemen’s coast who gave their assistance to its research

Anterior cruciate ligament injuries of the knee: Patterns of association between the mechanism of injury and pathology visualised on magnetic resonance imaging

Background: Anterior cruciate ligament (ACL) injuries are common among athletes and the general public. These injuries may lead to significant absence from all activities with associated financial and social burdens for the patient. No definitive association has been described between the mechanism of injury and the pathology to enable the implementation of preventative measures to limit these injuries.Aim: To determine whether there is an association between the mechanism of injury and the pathology seen on a magnetic resonance imaging (MRI) scan in ACL injuries.Methods: This was a cross-sectional analytical study. Eighty-seven male patients with an ACL injury and who had an MRI scan of the knee within the last two years participated in this study. Participants were contacted to give their informed consent to participate in this study. The mechanism of injury and the pathology seen on the MRI scan was noted and categorised into different groups of injuries and associated pathologies. Statistical analyses included summaries of the data and a test for the association between the mechanism of injury and the pathology. Since there were multiple pathology responses to each mechanism, a modified version of the chi-square test for independence was used. A five percent level of significance was specified.Results: MRI scans of ACL injuries indicated that the mechanism of a solid foot plant with rotation of the knee has a greater tendency to be associated with medial meniscal injuries (77%). There was also a 54% possibility for it to be associated with lateral meniscal injuries. A solid foot plant with a valgus stress on the knee showed a higher incidence of associated medial collateral ligament (MCL) injuries (41%) and femoral bone bruising (62%). These two mechanisms of injury are the most common in ACL injuries and contribute to the clinical significance found in this study. The p-value was, however, not statistically significant (p=0.44, chi-square value=20.27, df=45) for any association between the pathology and the mechanism of injury.Conclusion: Some injury mechanisms causing an ACL injury were more common than others and had more associated pathologies. The most common mechanism of injury noted in this study was a solid foot plant with either rotation of the knee or valgus stress on the knee. Strengthening the tissue structures involved in those movement patterns causing these mechanisms can possibly limit future ACL injuries in athletes and the general public.Keywords: knee injury, mechanism, association, pathology, MRI scan, preventio

Genetic basis of rifampicin resistance in methicillin-resistant Staphylococcus aureus suggests clonal expansion in hospitals in Cape Town, South Africa

<p>Abstract</p> <p>Background</p> <p>Since 2001, several studies have reported high rifampicin resistance rates (45 - 100%) among methicillin-resistant <it>Staphylococcus aureus </it>(MRSA) isolates from South Africa. The authors previously characterised 100 MRSA isolates from hospitals in Cape Town, South Africa; forty-five percent of these isolates were rifampicin-resistant. The majority (44/45) corresponded to ST612-MRSA-IV, which is prevalent in South Africa, but has not been reported frequently elsewhere. The remaining rifampicin-resistant isolate corresponded to ST5-MRSA-I. The aim of this study was to investigate further the prevalence and genetic basis of rifampicin-resistance in MRSA isolates from hospitals in Cape Town.</p> <p>Results</p> <p>Between July 2007 and June 2011, the prevalence of rifampicin-resistant MRSA in hospitals in Cape Town ranged from 39.7% to 46.4%. Based on the results of the aforementioned study, nine ST612-MRSA-IV isolates, the rifampicin-resistant ST5-MRSA-I isolate, and two rifampicin-susceptible MRSA isolates were investigated. Four previously described ST612-MRSA-IV isolates, including two each from South Africa and Australia, were also included.</p> <p>The ST5-MRSA-I isolate carried a single mutational change, H₄₈₁Y, commonly associated with high-level rifampicin resistance. All ST612-MRSA-IV isolates carried an uncommon double amino acid substitution in RpoB, H₄₈₁N, I₅₂₇M, whilst one of the Australian ST612-MRSA-IV isolates carried an additional mutation within <it>rpoB</it>, representing a novel <it>rpoB </it>genotype: H₄₈₁N, I₅₂₇M, K₅₇₉R. All ST612-MRSA-IV isolates also shared a unique silent single nucleotide polymorphism (SNP) within <it>rpoB</it>.</p> <p>Conclusions</p> <p>That local ST612-MRSA-IV isolates described here share an uncommon <it>rpoB </it>genotype and a unique silent SNP suggests this clone may have undergone clonal expansion in hospitals in Cape Town. Further, the data suggest that these isolates may be related to rifampicin-resistant ST612-MRSA-IV previously described in South Africa and Australia.</p

The influence of service brand equity on the strength of brand relationships in the fast food industry

The South African fast food industry is growing fast and rivals are competing fiercely, providing customers with an array of different choices. Given this situation, it has become increasingly important for fast food organisations to focus on elevating and sustaining a competitive advantage. One way of doing this is by maximising brand equity. In doing so, organisations can differentiate themselves in the minds of customers by encouraging a relationship with their brand. The aim of this study is to determine the influence of service brand equity on customers’ relationships with their fast food brand. The population comprised fast food customers residing in the North West Province of South Africa. A cross-sectional descriptive design was followed, and a convenience sample was used to select respondents. Data were obtained by means of a self-administered questionnaire, realising 379 responses. A multiple regression analysis indicates that three brand equity dimensions, namely brand awareness, brand association and brand trust, significantly and positively influence the strength of the relationships that respondents have with their favourite fast food brand (with brand trust being the most influential dimension). Fast food outlets can, therefore, strengthen their customers’ brand relationships by focusing specifically on improving these three dimensions.Key words: service brand equity, brand awareness, perceived quality, brand differentiation, brand associations, brand trust, brand relationships, fast food industry, fast food outlet

A cross-sectional study of 2550 amateur cyclists shows lack of knowledge regarding relevant sports nutrition guidelines

&nbsp; &nbsp;Background: Amateur cyclists use a wide variety of supplements and nutritional substances to increase performance in addition to their training.&nbsp; Objectives: The intended nutritional supplement use, carbohydrate (CHO) use and hydration practices of amateur cyclists before, during and after endurance cycling were analysed. Evidence of ignorance regarding the use of sports supplements and CHO, as well as the disregard of hydration strategy was hypothesised.&nbsp; Methods: Amateur cyclists, of all age and sex groups, were requested to complete an online survey anonymously on the 2013 Momentum 94.7 Cycle Challenge website, a few days before the event.&nbsp; Results: Responses were received from 2 550 out of 30 640 race entrants (8%); representing a distribution of 75% males, 25% females, with the majority between 25 to 45 years old. Nutritional supplements were used by 59% of respondents, with 77% dose adherence, and 29% with supplement ingredient knowledge. Half of the respondents (48%) planned to carbo-load two-three days before the event, while only five percent used professional advice to scientifically calculate their carbo-loading requirements. CHO were consumed by 81% during the event. Hydration preferences during the race were sports drinks (59%) and water (22%); and after the race 45% preferred a sports drink and 40% water. Ingredients, taste, colour, and temperature were criteria used to choose a sports drink. Only 18% of respondents knew to use both colour of urine and thirstiness to determine post-race fluid requirements.&nbsp; Conclusion: The authors concluded that amateur cyclists had insufficient knowledge regarding nutritional supplement ingredients and usage, CHO requirements and carbo-loading practices, and hydration strategies before, during and after the event.&nbsp

The use of negative pressure wave treatment in athlete recovery

Background: Athletes need to recover fully to maximise performance in competitive sport. Athletes who replenish more quickly and more efficiently are able to train harder and more intensely. Elite athletes subjectively report positive results using lower body negative pressure (LBNP) treatment as an alternate method for rapid recovery, restoring and improving their impaired physical state. Objective data on the efficacy are lacking.Objectives: To investigate the effect of intermittent vacuum therapy on accelerating acute recovery following an athlete’s normal daily training schedule of strenuous exercise. Objective measurements of biological markers of muscular fatigue were used to assess recovery.Methods: Twenty-two male cricket players in a randomised cross-over study were divided into a treatment and control group respectively. Following a one-hour high-intensity gym session, the treatment group received three 30-minute LBNP exposure sessions over three consecutive days (0, 24 and 48 hours). Blood lactate and creatine kinase biomarkers were collected to measure the recovery process. After 14 days groups were crossed over and the trial repeated.Results: Heart rate and blood pressure decreased noticeably during treatment, reverting to baseline levels after treatment. Lactate concentrations decreased in both groups after exercise termination; significantly more in the treatment (0.57±0.23 mmol/l) than control group (0.78±0.22 mmol/l), p&lt;0.001). Creatine kinase (CK) was similar in both groups. Athletes’ subjective assessments of recovery rated moderately high.Conclusion: LBNP therapy applied as treatment during routine schedule may have a systemic effect in lowering serum lactate levels, but not CK levels. Enhanced recovery of athletes is still unconfirmed

Overground versus underground : a genetic insight into dispersal and abundance of the Cape dune mole-rat

Molecular methods are commonly used to investigate cryptic populations that are difficult to locate or observe directly. The population dynamics of many subterranean organisms have been overlooked, at least in part, as a result of the absence of appropriate molecular markers. Recent studies in African mole-rats have raised questions about the modes of dispersal and mate acquisition. In the present study, we apply a suite of 25 microsatellite markers to test the overground/underground dispersal hypotheses. Using these data, we also apply an approach to estimate population size and look for signal of demographic expansion or contraction. The genetic data suggest that the same breeding population extends between locations (approximately 50 km), with elevated inbreeding coefficients suggestive of some degree of isolation of the urban location. Low genetic differentiation between study sites supports the proposed high levels of vagility of dispersing individuals overground. We find a signal of long-term population decline of Bathyergus suillus in this region. Their adherence to mesic conditions potentially recommends B. suillus to be of utility in monitoring the proposed climate-induced desiccation of the Western Cape. Of potential interest is the discovery of a second divergent population at the rural location, with microsatellite data suggesting contemporary reproductive isolation and a mitochondrial divergence putatively dated at approximately 0.6 Mya.University of Pretoria.DST-NRF SARChI Chair for Mammal behavioural ecology and physiology.http://onlinelibrary.wiley.com/journal/10.1111/(ISSN)1095-8312hb201