Radiation and magnetic field effects on new semiconductor power devices for HL-LHC experiments

The radiation hardness of commercial Silicon Carbide and Gallium Nitride power MOSFETs is presented in this paper, for Total Ionizing Dose effects and Single Event Effects, under gamma, neutrons, protons and heavy ions. Similar tests are discussed for commercial DC-DC converters, also tested in operation under magnetic field

Histochemical and morpho-metrical study of mouse intestine epithelium after a long term diet containing genetically modified soybean

Diet can influence the structural characteristics of both small and large intestine. In this study, we investigated the duodenum and colon of mice fed on genetically modified (GM) soybean during their whole life span (1–24 months) by focusing our attention on the histological and ultrastructural characteristics of the epithelium, the histochemical pattern of goblet cell mucins, and the growth profile of the coliform population. Our results demonstrate that controls and GM-soybean fed mice are similarly affected by ageing. Moreover, the GM soybean-containing diet does not induce structural alterations in duodenal and colonic epithelium or in coliform population, even after a long term intake. On the other hand, the histochemical approach revealed significant diet-related changes in mucin amounts in the duodenum. In particular, the percentage of villous area occupied by acidic and sulpho-mucin granules decreased from controls to GM-fed animals, whereas neutral mucins did not change

Genetic variability of Haemonchus contortus (Nematoda: Trichostrongyloidea) in alpine ruminant host species

Genetic variability of the ovine parasite Haemonchus contortus from the Alpine area was investigated using mitochondrial DNA (nd4 gene), internal transcribed spacers 1 and 2 and microsatellites, in order to assess whether cross-transmission between domestic and wild ruminants occurs. The dataset was composed of 78 individual adult male H. contortus collected from chamois (Rupicapra r. rupicapra), roe deer (Capreolus capreolus), alpine ibex (Capra ibex ibex), domestic goat (Capra hircus) and sheep (Ovis aries) from different alpine areas. The data obtained show low host specificity and high genetic variation within H. contortus populations. The analyses indicate the presence of two mitochondrial haplotype clusters among host species and the absence of cryptic parasite species, confirming H. contortus as a generalist nematode and suggesting that parasite transmission between populations of domestic and wild ruminants normally occurs

HEXIT-SAT: a mission concept for X-ray grazing incidence telescopes from 0.5 to 70 keV

While the energy density of the Cosmic X-ray Background (CXB) provides a statistical estimate of the super massive black hole (SMBH) growth and mass density in the Universe, the lack, so far, of focusing instrument in the 20-60 keV (where the CXB energy density peaks), frustrates our effort to obtain a comprehensive picture of the SMBH evolutionary properties. HEXIT-SAT (High Energy X-ray Imaging Telescope SATellite) is a mission concept capable of exploring the hard X-ray sky with focusing/imaging instrumentation, to obtain an unbiased census of accreting SMBH up to the redshifts where galaxy formation peaks, and on extremely wide luminosity ranges. This will represent a leap forward comparable to that achieved in the soft X-rays by the Einstein Observatory in the late 70'. In addition to accreting SMBH, and very much like the Einstein Observatory, this mission would also have the capabilities of investigating almost any type of the celestial X-ray sources. HEXIT-SAT is based on high throughput (>400 cm2 @ 30 keV; >1200 cm2 @ 1 keV), high quality (15 arcsec Half Power Diameter) multi-layer optics, coupled with focal plane detectors with high efficiency in the full 0.5-70keV range. Building on the BeppoSAX experience, a low-Earth, equatorial orbit, will assure a low and stable particle background, and thus an extremely good sensitivity for faint hard X-ray sources. At the flux limits of 1/10 microCrab (10-30 keV) and 1/3 microCrab (20-40 keV) (reachable in one Msec observation) we should detect ~100 and ~40 sources in the 15 arcmin FWHM Field of View respectively, thus resolving >80% and ~65% of the CXB where its energy density peaks.Comment: to appear in Proceeedings of SPIE Vol. 5488, UV to Gamma Ray Space Telescope System

Cone-beam computed tomography accuracy in pulp chamber size evaluation: An ex vivo study

This study aimed to assess ex vivo the accuracy of cone-beam computed tomography (CBCT), as compared to operative microscope, for evaluating pulp chamber size. A total of forty teeth were extracted for periodontal reasons and a horizontal section was done at the most apical level of the cement-enamel junction. The pulp chamber was photographed using a digital camera connected to an optical microscope. Then, the tooth was scanned with CBCT and the horizontal slide matching the anatomical section of pulp chamber was digitally stored. The pulp chamber section area was measured through image analysis software. The two methods provided similar results, either for monoradicular (P = 0.14) or multiradicular teeth (P = 0.93). Correlation was statistically significant (P < 0.0001), being the coefficient r = 0.89 and 0.94 for monoradicular and multiradicular teeth, respectively. Conclusively, CBCT is suitable for pulp chamber morphology evaluation. However, it has limitations in detecting the anatomical variability of small branches in root canal system

Detector Control System of the ATLAS Insertable B-Layer

soumis à publicationTo improve tracking robustness and precision of the ATLAS inner tracker an additional fourth pixel layer is foreseen, called Insertable B-Layer (IBL). It will be installed between the innermost present Pixel layer and a new smaller beam pipe and is presently under construction. As, once installed into the experiment, no access is available, a highly reliable control system is required. It has to supply the detector with all entities required for operation and protect it at all times. Design constraints are the high power density inside the detector volume, the sensitivity of the sensors against heatups, and the protection of the front end electronics against transients. We present the architecture of the control system with an emphasis on the CO2 cooling system, the power supply system and protection strategies. As we aim for a common operation of pixel and IBL detector, the integration of the IBL control system into the Pixel one will be discussed as well

Sustainable Synthesis of N-Alkyl-Pyrrolecarboxylic and Pyrrolepyrazinones Derivatives from Biosourced 3-Hydroxy-2-pyrones and Amines

Pyrroles are important compounds present in biological systems, used for drug synthesis and in material chemistry. A typical strategy for the pyrrolic ring formation is centered on the Paal−Knorr reaction, where 1,4-dicarbonyl compounds react with amines giving N-substituted pyrrole derivatives. Often, the main problem of this approach is the availability of the appropriate carbonyl compounds. Here, we report a sustainable synthesis of N-substituted pyrrole carboxylic acid derivatives by the reaction of primary amines and 3-hydroxy-2-pyrones. These last compounds can easily be prepared using renewable sources and show the property to be masked 1,4-dicarbonyl compounds that are able to react efficiently with amines to form substituted pyrrolic rings. The reactions can be performed under sustainable conditions without solvents at 50−75 °C or in basic water−methanol solutions at room temperature, obtaining symmetric and asymmetric pyrroles from good to high yields. Moreover, dihydropyrrolepyrazinone derivatives can easily be prepared in high yields by the reaction of 3-hydroxy-2-pyrones and ethylenediamine