Axon diameter measurements using diffusion MRI are infeasible

The feasibility of non-invasive axonal diameter quantification with diffusion MRI is a strongly debated topic due to the neuroscientific potential of such information and its relevance for the axonal signal transmission speed. It has been shown that under ideal conditions, the minimal diameter producing detectable signal decay is bigger than most human axons in the brain, even using the strongest currently available MRI systems. We show that resolving the simplest situations including multiple diameters is unfeasible even with diameters much bigger than the diameter limit. Additionally, the recently proposed effective diameter resulting from fitting a single value over a distribution is almost exclusively influenced by the biggest axons. We show how impractical this metric is for comparing different distributions. Overall, axon diameters currently cannot be quantified by diffusion MRI in any relevant way

De-noising of diffusion-weighted MRI data by averaging of inconsistent input data in wavelet space

Diffusion Weighted Images datasets with high spatial resolution and strong diffusion weighting are often deteriorated with low SNR. Here, we demonstrate the feasibility of a recently presented repetition-free averaging based de-noising (AWESOME). That technique reduces noise by averaging over a series of N images with varying contrast in wavelet space and regains intensities and object features initially covered by noise. We show that high resolution DWIs are achievable in a quality that almost equals to that obtained from 6fold complex averaging

LUX -- A Laser-Plasma Driven Undulator Beamline

The LUX beamline is a novel type of laser-plasma accelerator. Building on the joint expertise of the University of Hamburg and DESY the beamline was carefully designed to combine state-of-the-art expertise in laser-plasma acceleration with the latest advances in accelerator technology and beam diagnostics. LUX introduces a paradigm change moving from single-shot demonstration experiments towards available, stable and controllable accelerator operation. Here, we discuss the general design concepts of LUX and present first critical milestones that have recently been achieved, including the generation of electron beams at the repetition rate of up to 5 Hz with energies above 600 MeV and the generation of spontaneous undulator radiation at a wavelength well below 9 nm.Comment: submitte

Mapping the human lateral geniculate nucleus and its cytoarchitectonic subdivisions using quantitative MRI

International audienc

De-noising of diffusion-weighted MRI data by averaging of inconsistent input data in wavelet space

Diffusion Weighted Images datasets with high spatial resolution and strong diffusion weighting are often deteriorated with low SNR. Here, we demonstrate the feasibility of a recently presented repetition-free averaging based de-noising (AWESOME). That technique reduces noise by averaging over a series of N images with varying contrast in wavelet space and regains intensities and object features initially covered by noise. We show that high resolution DWIs are achievable in a quality that almost equals to that obtained from 6fold complex averaging

Improved limits on nuebar emission from mu+ decay

We investigated mu+ decays at rest produced at the ISIS beam stop target. Lepton flavor (LF) conservation has been tested by searching for \nueb via the detection reaction p(\nueb,e+)n. No \nueb signal from LF violating mu+ decays was identified. We extract upper limits of the branching ratio for the LF violating decay mu+ -> e+ \nueb \nu compared to the Standard Model (SM) mu+ -> e+ nue numub decay: BR < 0.9(1.7)x10^{-3} (90%CL) depending on the spectral distribution of \nueb characterized by the Michel parameter rho=0.75 (0.0). These results improve earlier limits by one order of magnitude and restrict extensions of the SM in which \nueb emission from mu+ decay is allowed with considerable strength. The decay \mupdeb as source for the \nueb signal observed in the LSND experiment can be excluded.Comment: 10 pages, including 1 figure, 1 tabl

Weak lensing analysis of RXC J2248.7-4431

We present a weak lensing analysis of the cluster of galaxies RXC J2248.7-4431, a massive system at z=0.3475 with prominent strong lensing features covered by the HST/CLASH survey (Postman et al. 2012). Based on UBVRIZ imaging from the WFI camera at the MPG/ESO-2.2m telescope, we measure photometric redshifts and shapes of background galaxies. The cluster is detected as a mass peak at 5sigma significance. Its density can be parametrised as an NFW profile (Navarro et al. 1996) with two free parameters, the mass M_200m=(33.1+9.6-6.8)x10^14Msol and concentration c_200m=2.6+1.5-1.0. We discover a second cluster inside the field of view at a photometric redshift of z~0.6, with an NFW mass of M_200m=(4.0+3.7-2.6)x10^14Msol.Comment: 15 pages, 17 figures; matching published versio

Power-law persistence and trends in the atmosphere: A detailed study of long temperature records

We use several variants of the detrended fluctuation analysis to study the appearance of long-term persistence in temperature records, obtained at 95 stations all over the globe. Our results basically confirm earlier studies. We find that the persistence, characterized by the correlation C(s) of temperature variations separated by s days, decays for large s as a power law, C(s) ~ s^(-gamma). For continental stations, including stations along the coastlines, we find that gamma is always close to 0.7. For stations on islands, we find that gamma ranges between 0.3 and 0.7, with a maximum at gamma = 0.4. This is consistent with earlier studies of the persistence in sea surface temperature records where gamma is close to 0.4. In all cases, the exponent gamma does not depend on the distance of the stations to the continental coastlines. By varying the degree of detrending in the fluctuation analysis we obtain also information about trends in the temperature records.Comment: 5 pages, 4 including eps figure

Golden gravitational lensing systems from the Sloan Lens ACS Survey. I. SDSS J1538+5817: one lens for two sources

We present a lensing and photometric study of the exceptional system SDSS J1538+5817, identified by the SLACS survey. The lens is a luminous elliptical at redshift z=0.143. Using HST public images in two different filters, the presence of two background sources lensed into an Einstein ring and a double system is ascertained. Our new spectroscopic observations, performed at the NOT, reveal that the two sources are located at the same redshift z=0.531. We investigate the total mass distribution of the lens between 1 and 4 kpc from the galaxy center by means of parametric and non-parametric lensing codes that describe the multiple images as point-like objects. Several disparate lensing models agree on: (1) reproducing accurately the observed image positions; (2) predicting a nearly axisymmetric total mass distribution, centered and oriented as the light distribution; (3) measuring a value of 8.11 x 10^{10} M_{Sun} for the total mass projected within the Einstein radius of 2.5 kpc; (4) estimating a total mass density profile slightly steeper than an isothermal one. A fit of the SDSS multicolor photometry with CSP models provides a value of 20 x 10^{10} M_{Sun} for the total stellar mass of the galaxy and of 0.9 for the fraction of projected luminous over total mass enclosed inside the Einstein radius. By combining lensing and photometric mass measurements, we differentiate the lens mass content in terms of luminous and dark matter components. This two-component modeling, which is viable only in extraordinary systems like SDSS J1538+5817, leads to a description of the global properties of the galaxy dark matter halo. Extending these results to a larger number of lenses would improve considerably our understanding of galaxy formation and evolution processes in the LCDM scenario.Comment: 21 pages, 16 figures, accepted by The Astrophysical Journa