Liquid uptake in porous cellulose sheets studied with UFI-NMR:Penetration, swelling and air displacement

Liquid penetration in porous cellulosic materials is crucial in many technological fields. The complex geometry, small pore size, and often fast timescale of liquid uptake makes the process hard to capture. Effects such as swelling, vapor transport, film flow and water transport within cellulosic material makes transport deviate from well-known relations such as Lucas-Washburn and Darcy's Law. In this work it is demonstrated how Ultra-Fast Imaging NMR can be used to simultaneously monitor the liquid distribution and swelling during capillary uptake of water with a temporal- and spatial resolution of 10 ms and 14.5–18 μm respectively. The measurements show that in a cellulose fiber sheet, within the first 65 ms, liquid first penetrates the whole sheet before swelling takes place for another 30 s. Furthermore, it was observed that the liquid front traps 15 v% of air which is slowly replaced by water during the final stage of liquid uptake. Our method makes it possible to simultaneously quantify the concentration of all three phases (solid, liquid and air) within porous materials during processes exceeding 50 ms (5 times the temporal resolution). We hence believe that the proposed method should also be useful to study liquid penetration, or water diffusion, into other porous cellulosic materials like foams, membranes, nonwovens, textiles and films.</p

Topological solitons in highly anisotropic two dimensional ferromagnets

e study the solitons, stabilized by spin precession in a classical two--dimensional lattice model of Heisenberg ferromagnets with non-small easy--axis anisotropy. The properties of such solitons are treated both analytically using the continuous model including higher then second powers of magnetization gradients, and numerically for a discrete set of the spins on a square lattice. The dependence of the soliton energy $E$ on the number of spin deviations (bound magnons) $N$ is calculated. We have shown that the topological solitons are stable if the number $N$ exceeds some critical value $N_{\rm{cr}}$. For $N < N_{\rm{cr}}$ and the intermediate values of anisotropy constant $K_{\mathrm{eff}} <0.35J$ ($J$ is an exchange constant), the soliton properties are similar to those for continuous model; for example, soliton energy is increasing and the precession frequency $\omega (N)$ is decreasing monotonously with $N$ growth. For high enough anisotropy $K_{\mathrm{eff}} > 0.6 J$ we found some fundamentally new soliton features absent for continuous models incorporating even the higher powers of magnetization gradients. For high anisotropy, the dependence of soliton energy E(N) on the number of bound magnons become non-monotonic, with the minima at some "magic" numbers of bound magnons. Soliton frequency $\omega (N)$ have quite irregular behavior with step-like jumps and negative values of $\omega$ for some regions of $N$. Near these regions, stable static soliton states, stabilized by the lattice effects, exist.Comment: 17 page

Liquid penetration in hydrophobised cellulose based sheets

Controlling the liquid transport within cellulose-based materials is crucial for numerous applications, including printing, bio-assays, packaging, and cleaning. To control liquid transport and quality, post-processes such as calendering, a way of compressing and smoothen the paper using hard pressure rollers, and hydrophobisation, are commonly employed. To understand how these processes influence liquid uptake, this study uses an Ultra-Fast Imaging (UFI) NMR method to analyse moisture profiles during liquid uptake in various cellulose-based paper sheets with diverse levels of hydrophobisation and calendering. It is demonstrated that calendering decreases penetration speed and increases swelling. The reduction in penetration speed could be linked to a decrease in permeability upon calendering, as measured by the Gurley air permeance. Additionally, it is observed that hydrophobisation delayed and slowed down liquid uptake in the paper samples, and, in extreme cases, completely altered the liquid uptake phenomena. With substantial hydrophobisation, liquid penetration no longer proceeded with a well-defined liquid front but exhibited huge levels of fingering. Furthermore, is was observed that within highly hydrophobised paper, fibres were first prewetted, initiating a first swelling, before the pores between fibres could be filled. Subsequently, water could enter the pores between, allowing fibre bonds to be broken, leading to a second swelling of the paper sheet. The improved understanding will contribute to better control of the flow within cellulose-based materials, benefiting applications such as printing, packaging and microfluidics.</p

Estimation of sensitivity and specificty of culture and Danish-mix ELISA for detection of Salmonella in swine using Bayesian methods

Both bacterial culture and serological assays, such as the Danish-mix ELISA for the detection of antibodies, are commonly used as tools for detecting and monitoring Salmonella in swine. The comparison and ultimate interpretation of results are made more difficult due to the absence of a gold standard

Quality of anticholinergic burden scales and their impact on clinical outcomes: a systematic review.

Older people are at risk of anticholinergic side effects due to changes affecting drug elimination and higher sensitivity to drug's side effects. Anticholinergic burden scales (ABS) were developed to quantify the anticholinergic drug burden (ADB). We aim to identify all published ABS, to compare them systematically and to evaluate their associations with clinical outcomes. We conducted a literature search in MEDLINE and EMBASE to identify all published ABS and a Web of Science citation (WoS) analysis to track validation studies implying clinical outcomes. Quality of the ABS was assessed using an adapted AGREE II tool. For the validation studies, we used the Newcastle-Ottawa Scale and the Cochrane tool Rob2.0. The validation studies were categorized into six evidence levels based on the propositions of the Oxford Center for Evidence-Based Medicine with respect to their quality. At least two researchers independently performed screening and quality assessments. Out of 1297 records, we identified 19 ABS and 104 validations studies. Despite differences in quality, all ABS were recommended for use. The anticholinergic cognitive burden (ACB) scale and the German anticholinergic burden scale (GABS) achieved the highest percentage in quality. Most ABS are validated, yet validation studies for newer scales are lacking. Only two studies compared eight ABS simultaneously. The four most investigated clinical outcomes delirium, cognition, mortality and falls showed contradicting results. There is need for good quality validation studies comparing multiple scales to define the best scale and to conduct a meta-analysis for the assessment of their clinical impact

Summarizing the evidence of the performance of diagnostic tests for Salmonella spp. in swine: A systematic review approach

A systematic review was undertaken in order to identify, critically appraise and synthesize the existing literature on the diagnostic performance (e.g. Se and Sp of the test) and agreement (e.g. kappa and correlation coefficients) of conventional bacterial culture, enzyme-linked immunosorbent assays and polymerase chain reaction assays used to detect and monitor Salmonella spp. in swine. 2110 citations were identified and 160 were relevant to the research objectives. Quality assessment is complete for 150 of these references; 73 were excluded due to estimates of test performance not being clearly reported and insufficient raw data available for post-hoc analysis. Although the review is still in progress, early experiences indicate problems with lack of standardization in the design, conduct and reporting of studies of diagnostic test evaluation in this area. This review will provide valuable information by identifying gaps in existing research and providing direction for future work on the standardization of tests examined in this review

Explanation and Elaboration Document for the STROBE-Vet Statement: Strengthening the Reporting of Observational Studies in Epidemiology—Veterinary Extension

The STROBE (Strengthening the Reporting of Observational Studies in Epidemiology) statement was first published in 2007 and again in 2014. The purpose of the original STROBE was to provide guidance for authors, reviewers and editors to improve the comprehensiveness of reporting; however, STROBE has a unique focus on observational studies. Although much of the guidance provided by the original STROBE document is directly applicable, it was deemed useful to map those statements to veterinary concepts, provide veterinary examples and highlight unique aspects of reporting in veterinary observational studies. Here, we present the examples and explanations for the checklist items included in the STROBE-Vet Statement. Thus, this is a companion document to the STROBE-Vet Statement Methods and process document, which describes the checklist and how it was developed

Soliton-Magnon Scattering in Two-Dimensional Isotropic Ferromagnets

It is studied the scattering of magnons by the 2d topological Belavin-Polyakov soliton in isotropic ferromagnet. Analytical solutions of the scattering problem are constructed: (i) exactly for any magnon wave vectors for the partial wave with the azimuthal number m=1 (translational mode), and (ii) in the long- and short-wave limits for the rest modes. The magnon mode frequencies are found for the finite size magnets. An effective equation of the soliton motion is constructed. The magnon density of states, connected with the soliton-magnon interaction, is found in a long-wave approximation.Comment: 4 pages, REVTe

The academic, economic and societal impacts of Open Access: an evidence-based review

Ongoing debates surrounding Open Access to the scholarly literature are multifaceted and complicated by disparate and often polarised viewpoints from engaged stakeholders. At the current stage, Open Access has become such a global issue that it is critical for all involved in scholarly publishing, including policymakers, publishers, research funders, governments, learned societies, librarians, and academic communities, to be well-informed on the history, benefits, and pitfalls of Open Access. In spite of this, there is a general lack of consensus regarding the potential pros and cons of Open Access at multiple levels. This review aims to be a resource for current knowledge on the impacts of Open Access by synthesizing important research in three major areas: academic, economic and societal. While there is clearly much scope for additional research, several key trends are identified, including a broad citation advantage for researchers who publish openly, as well as additional benefits to the non-academic dissemination of their work. The economic impact of Open Access is less well-understood, although it is clear that access to the research literature is key for innovative enterprises, and a range of governmental and non-governmental services. Furthermore, Open Access has the potential to save both publishers and research funders considerable amounts of financial resources, and can provide some economic benefits to traditionally subscription-based journals. The societal impact of Open Access is strong, in particular for advancing citizen science initiatives, and leveling the playing field for researchers in developing countries. Open Access supersedes all potential alternative modes of access to the scholarly literature through enabling unrestricted re-use, and long-term stability independent of financial constraints of traditional publishers that impede knowledge sharing. However, Open Access has the potential to become unsustainable for research communities if high-cost options are allowed to continue to prevail in a widely unregulated scholarly publishing market. Open Access remains only one of the multiple challenges that the scholarly publishing system is currently facing. Yet, it provides one foundation for increasing engagement with researchers regarding ethical standards of publishing and the broader implications of 'Open Research'

Internal Modes and Magnon Scattering on Topological Solitons in 2d Easy-Axis Ferromagnets

We study the magnon modes in the presence of a topological soliton in a 2d Heisenberg easy-axis ferromagnet. The problem of magnon scattering on the soliton with arbitrary relation between the soliton radius R and the "magnetic length" Delta_0 is investigated for partial modes with different values of the azimuthal quantum numbers m. Truly local modes are shown to be present for all values of m, when the soliton radius is enough large. The eigenfrequencies of such internal modes are calculated analytically on limiting case of a large soliton radius and numerically for arbitrary soliton radius. It is demonstrated that the model of an isotropic magnet, which admits an exact analytical investigation, is not adequate even for the limit of small radius solitons, R<<Delta_0: there exists a local mode with nonzero frequency. We use the data about local modes to derive the effective equation of soliton motion; this equation has the usual Newtonian form in contrast to the case of the easy-plane ferromagnet. The effective mass of the soliton is found.Comment: 33 pages (REVTeX), 12 figures (EPS