Sistema de monitoramento e alerta de inundações e secas no Pantanal.

The regime of floods and droughts in the Pantanal wetlands determines the distribution and abundance of the wildlife, vegetation and ecological processes. Cattle ranching and fisheries, the main economic activities in this floodplain, are extremely influenced by and depend on this regime. The aim of this work is to propose a Monitoring and Alert System, denoted SISMONPAN, of floods and droughts in the Pantanal for a better management, conservation and decision making, especially in the case of extreme events. A ten years time series, from 2000 to 2009, of estimated satellite precipitation, river stages and flood mapping derived from MODIS surface reflectance bands processed by the unmixing spectral model was analyzed. The main hydrological compartments and their relationships were defined using previous knowledge in the region as well as correlation statistical models derived from upstream - downstream water fluxes. The power and time lag of the correlations between the water fluxes in the hydrological compartments were determined. These data, flood maps and obtained relationships were organized in a database to be used by the monitoring and alert system for the Pantanal region. The SISMONPAN was developed in PHP language using TerraView and TerraLib libraries in its architecture. The system will be available on the Internet, allowing any stakeholder to simulate possible scenarios of floods and droughts based both on the predetermined upstream-downstream water flux relationships and previous events stored in the database

Análise de áreas com diferentes classes de declividade através de imagens TM/LANDSAT

The analysis of areas with different slope classes (A = 0-3%, B = 3-8%, C = 8-16% and D = 16-30%) is made with the purpose of verifying the TM/LANDSAT images potentiality in agricultural planning. Due to the absence of tridimensional viewing, the work is based on quantitative relations between drainage indices (river frequency and drainage density) determined on the images, and the relief expression (average slope) extracted from planialtimetric topographic charts (1: 50,000 scale). Aerial photographs on a 1:35,000 escale are utilized for comparisons. The main conclusion is that the utilization of TM/LANDSAT images in mapping slope classes through drainage network is feasible, though the characteristics of the analysed region caused an easier differentiation between areas of the A and B classes and those of the C and D classes.É feita a análise de áreas com diferentes classes de declividade (A = 0-3%, B = 3-8%, C = 8-16% e D = 16-30%) sscom a fina1idade de se verificar a potencialidade de imagens TM/LANDSAT, na escala 1:100.000, para planejamento agrícola. Devido à ausência de visão tridimensional, o trabalho baseia-se nas relações quantitativas entre índices dedrenagem (freqüência de rios e densidade de drenagem) determinados a partir das imagens, e expressão do relevo (declividade média) extraída de cartas planialtimétricas, na escala 1:50.000. Fotografias aéreas na escala 1:35.000 são utilizadas para fins comparativos. Conclui-se que o uso dessas imagens para mapear classes de declividade através do padrão de drenagem é viável, embora as características regionais o tenham limitado para diferenciar mais facilmente áreas com declividades A e B de áreas com declividades C e D

Agronomic performance of super-sweet corn genotypes in the north of Rio de Janeiro.

We investigated the agronomic performance of super-sweet corn genotypes. Super-sweet corn genotypes were backcrossed with regionally adapted field varieties (CIMMYT 8 and Piranão 8). Eight morphological and yield-related traits were evaluated. A significant effect of interaction was observed between the five groups of genotypes (donor parents; super-sweet backcrossed parents; super-sweet intervarietal hybrids; common intervarietal corn hybrids; and field corn populations). Despite the low yield of genotype SH 2 Piranão, the hybrids resulting from interbreeding of the backcrossed parents for the improvement of super-sweet corn were promising. The agronomic performance of the super-sweet parents and their hybrids indicates the possibility of breeding lines with high genetic value to obtain single-cross hybrids and cultivars of super-sweet corn adapted to the northern region of the State of Rio de Janeiro

Dinâmica espectro-temporal MODIS em plantios de paricá (Schizolobium parahyba var. amazonicum (Huber ex. Ducke) Barneby) associada a diferentes condições hídricas do solo na Amazônia brasileira.

As características de absorção e reflectâncias nas faixas do vermelho e infravermelho próximo em dosséis, tanto de plantios como de vegetação natural, auxiliam na identificação de respostas espectrais em diversas condições de tempo e clima. Objetivou-se avaliar o comportamento espectral em plantios de paricá (Schizolobium parahyba var. amazonicum (Huber ex Ducke) Barneby) nos períodos de maior e de menor oferta hídrica, em Dom Eliseu, Pa. Foram analisados dados meteorológicos, balanços hídricos (CAD=300 mm) e respostas em NDVI (Normalized Difference Vegetation Index) extraídos do sensor MODIS (Moderate Resolution Imaging Spectroradiometer). As imagens-índice referentes aos meses de janeiro a dezembro foram processadas no software Envi 4.5 e retiradas amostras com base em dados de verdade terrestre. Os dados foram analisados estatisticamente, aplicando-se teste de média e análise de perfil por meio de técnicas uni e multivariadas. Verificou-se que existe tendência no vigor do paricá, com decrescimento de 0,85 a 0,68, nos meses de maior deficiência hídrica, em nível de significância de 5 %. Conclui-se que o NDVI respondeu significativamente à condição hídrica do solo, em plantios de paricá, no Estado do Pará

Augmented β-cell function and mass in glucocorticoid-treated rodents are associated with increased islet ir-β /AKT/mTOR and decreased AMPK/ACC and AS160 signaling

FAPESP - FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULOCNPQ - CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICOGlucocorticoid (GC) therapies may adversely cause insulin resistance (IR) that lead to a compensatory hyperinsulinemia due to insulin hypersecretion. The increased β-cell function is associated with increased insulin signaling that has the protein kinase B (AKT) substrate with 160 kDa (AS160) as an important downstream AKT effector. In muscle, both insulin and AMP-activated protein kinase (AMPK) signaling phosphorylate and inactivate AS160, which favors the glucose transporter (GLUT)-4 translocation to plasma membrane. Whether AS160 phosphorylation is modulated in islets from GC-treated subjects is unknown. For this, two animal models, Swiss mice and Wistar rats, were treated with dexamethasone (DEX) (1 mg/kg body weight) for 5 consecutive days. DEX treatment induced IR, hyperinsulinemia, and dyslipidemia in both species, but glucose intolerance and hyperglycemia only in rats. DEX treatment caused increased insulin secretion in response to glucose and augmented β-cell mass in both species that were associated with increased islet content and increased phosphorylation of the AS160 protein. Protein AKT phosphorylation, but not AMPK phosphorylation, was found significantly enhanced in islets from DEX-treated animals. We conclude that the augmented β-cell function developed in response to the GC-induced IR involves inhibition of the islet AS160 protein activity.Glucocorticoid (GC) therapies may adversely cause insulin resistance (IR) that lead to a compensatory hyperinsulinemia due to insulin hypersecretion. The increased β-cell function is associated with increased insulin signaling that has the protein kinase2014114FAPESP - FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULOCNPQ - CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICOFAPESP - FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULOCNPQ - CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICOsem informaçãosem informaçã

Mastectomy rates are decreasing in the era of service screening: a population-based study in Italy (1997-2001)

We enrolled all 2162 in situ and 21 148 invasive cases of breast cancer in 17 areas of Italy, diagnosed in 1997-2001. Rates of early cancer increased by 13.7% in the screening age group (50-69 years), and breast conserving surgery by 24.6%. Advanced cancer rates decreased by 19.4%, and mastectomy rates by 24.2%. Service screening did not increase mastectomy rates in the study population

Estratégias construtivas na busca de conforto térmico e eficiência energética em edificações unifamiliares de interesse social nas zonas bioclimáticas 1, 2 e 3 brasileiras

O objetivo desde estudo é apresentar estratégias construtivas passivas e de baixo custo para melhoria do conforto térmico e da eficiência energética em habitações de interesse social. Tem como foco as zonas bioclimáticas 1, 2 e 3 brasileiras, que se caracterizam por períodos bem definidos de elevadas e baixas temperaturas. Como referenciais teóricos foram utilizadas a Carta Bioclimática de Givoni, as Planilhas de Mahoney, a Norma NBR 15220 e conceitos de sustentabilidade. Os pré-requisitos adotados para a escolha das estratégias de projeto foram a flexibilidade de uso tanto para períodos frios como quentes, a facilidade de controle pelo usuário e a utilização de materiais reciclados e/ou de baixo custo. O projeto apresenta estratégia de calefação, que utiliza o insuflamento de ar aquecido do ático do telhado, para os períodos frios e para os períodos de elevada temperatura é proposto o uso de ventilação cruzada por diferença de pressão, esta é maximizada pelo uso de resfriamento evaporativo e massa térmica. Além disso, foi proposto um sistema alternativo de aquecimento solar da água com o uso de um painel solar associado à estrutura do telhado. Os sistemas foram propostos com a intenção de adaptar-se de maneira simples aos diferentes modelos construtivos e estéticos de habitações de baixo custo

Mean arterial blood pressure : potential predictive tool for preeclampsia in a cohort of healthy nulliparous pregnant women

Background: Prediction of preeclampsia is a challenge to overcome. The vast majority of prospective studies in large general obstetric populations have failed in the purpose of obtain a useful and effective model of prediction, sometimes based on complex tools unavaible in areas where the incidence of preeclampsia is the highest. The goal of this study was to assess mean arterial blood pressure (MAP) levels at 19–21, 27–29 and 37–39 weeks of gestation and performance of screening by MAP for the prediction of preeclampsia in a Brazilian cohort of healthy nulliparous pregnant women. Methods: This was a cohort approach to a secondary analysis of the Preterm SAMBA study. Mean arterial blood pressure was evaluated at three different time periods during pregnancy. Groups with early-onset preeclampsia, late-onset preeclampsia and normotension were compared. Increments in mean arterial blood pressure between 20 and 27 weeks and 20 and 37 weeks of gestation were also calculated for the three groups studied. The accuracy of mean arterial blood pressure in the prediction of preeclampsia was determined by ROC curves. Results: Of the 1373 participants enrolled, complete data were available for 1165. The incidence of preeclampsia was 7.5%. Women with early-onset preeclampsia had higher mean arterial blood pressure levels at 20 weeks of gestation, compared to the normotensive group. Women with late-onset preeclampsia had higher mean arterial blood pressure levels at 37 weeks of gestation, than the normotensive groups and higher increases in this marker between 20 and 37 weeks of gestation. Based on ROC curves, the predictive performance of mean arterial blood pressure was higher at 37 weeks of gestation, with an area under the curve of 0.771. Conclusion: As an isolated marker for the prediction of preeclampsia, the performance of mean arterial blood pressure was low in a healthy nulliparous pregnant women group. Considering that early-onset preeclampsia cases had higher mean arterial blood pressure levels at 20 weeks of gestation, future studies with larger cohorts that combine multiple markers are needed for the development of a preeclampsia prediction model