Pénfigo vulgar en un perro

Se describe un caso de pénfigo vulgar en un perro Pastor alemán, macho, de 8 años. El examen físico mostró lesiones eritematosas, vesiculares y ulcerativas en la cavidad oral, en diversas zonas de la piel y en las uniones cutáneomucosas de la nariz, del prepucio y del ano. A la vista del cuadro clínico, del estudio histopatológico y del test de inmunofluorescencia directa se estableció un diagnóstico de pénfigo vulgar. El tratamiento se basó en la administración oral de prednisona, azatioprina, amoxicilina-ácido clavulánico y vitamina E. Al cabo de tres meses las lesiones remitieron completamente. En la actualidad el animal se encuentra clínicamente controlado con prednisona a una dosis de mantenimiento de 0,5 mg/kg/2 días.A case of pemphigus vulgaris is described in an 8 year oId, male German Shepherd. Physical examination revealed erythematous, vesicular and ulcerative lesions in the mouth, in different areas of the skin and in the cutaneous-mucosal junctions of the nose, prepuce and anus. Based upon clinical findings, histopathological study, and dírect immunofluorescent test a diagnosis of pemphigus vulgaris was established. Treatment was based on oral administration of prednisone, azathioprine, amoxycillin-clavulanic acid and vitamin E. Complete remission was observed at three months. Presently the animal is clinically controlled with prednisone at a maintenance dose of 0,5 mg/kg on alternate days

Complejo granuloma eosinofílico

El complejo granuloma eosinofílico agrupa tres entidades clínico/histológicas denominadas granuloma colagenolítico, placa eosinofílica y úlcera indolente. En el presente artículo se describe su etiología y sus aspectos clínicos y terapéuticos.The eosinophilic granuloma complex is comprised of three clinical/histological entities: collagenolytic granuloma, eosinophilic plaque and indolent ulcer. In this article, its etiology, clinical aspects and therapy are discussed

Síndrome uveodermatológico en el perro

Se describe un caso de síndrome uveodermatológico en un perro Mastín español, macho, de 2 años. Los signos clínicos observados eran similares al síndrome de Vogt- Koyanagi-Harada humano y se caracterizaban por una uveitis asociada a una despigmentación y erosión cutánea y mucocutánea en cara, escroto, región perianal y almohadillas plantares. El estudio histopatológico reveló una dermatitis liquenoide, en la que predominaban los macrófagos. El tratamiento se basó en la administración oral de prednisona asociada a una terapia ocular tópica a base de atropina y corticosteroides. Al cabo de 8 meses las lesiones cutáneas y mucosas remitieron completamente.A case of uveodermatologic syndrome in a male 2 year old, Spanish Mastiff is described. The clinical signs found, namely uvezitis associated with cutaneus and mucocutaneous depigmentation and erosions of the face, scrotum, perianal region and footpads, were similar to those of the human Vogt-Koyanagi-Harada syndrome. The histopathological study showed a lichenoid dermatitis with prevalence of macrophages. The treatment encompassed the administration of prednisone per os and topical ocular therapy with corticosteroids associated with atropin e. After 8 months the cutaneous and mucosal Iesions had completely remitted

Unimodularity and invariant volume forms for Hamiltonian dynamics on Poisson-Lie groups

In this paper, we discuss several relations between the existence of invariant volume forms for Hamiltonian systems on Poisson-Lie groups and the unimodularity of the Poisson-Lie structure. In particular, we prove that Hamiltonian vector fields on a Lie group endowed with a unimodular Poisson-Lie structure preserve a multiple of any left-invariant volume on the group. Conversely, we also prove that if there exists a Hamiltonian function such that the identity element of the Lie group is a nondegenerate singularity and the associated Hamiltonian vector field preserves a volume form, then the Poisson-Lie structure is necessarily unimodular. Furthermore, we illustrate our theory with different interesting examples, both on semisimple and unimodular Poisson-Lie groups.Comment: 17 page

Automated FISH spots counting in interphase nuclei

ABSTRACT NUMBER 197Work supported by grant CYCIT (TIC92-0922)

SU(3) Chiral approach to meson and baryon dynamics

We report on recent progress on the chiral unitary approach, which is shown to have a much larger convergence radius than ordinary chiral perturbation theory, allowing one to reproduce data for meson meson interaction up to 1.2 GeV and meson baryon interaction up to the first baryonic resonances. Applications to physical processes so far unsuited for a standard chiral perturbative approach are presented, concretely the K⁻ p → Λ(1405) γ reaction and the N*(1535) N+(1535) π and η couplings

30-Day Mortality Following Palliative Radiotherapy

Indicador clínic; Radiació pal·liativa; PronòsticIndicador clínico: Radiación paliativa; PronósticoClinical indicator; Palliative radiation; PrognosisPurpose: 30-day mortality (30-DM) is a parameter with widespread use as an indicator of avoidance of harm used in medicine. Our objective is to determine the 30-DM followed by palliative radiation therapy (RT) in our department and to identify potential prognosis factors. Material/Methods: We conducted a retrospective cohort study including patients treated with palliative RT in our center during 2018 and 2019. Data related to clinical and treatment characteristics were collected. Results: We treated 708 patients to whom 992 palliative irradiations were delivered. The most frequent primary tumor sites were lung (31%), breast (14.8%), and gastrointestinal (14.8%). Bone was the predominant location of the treatment (56%), and the use of single doses was the preferred treatment schedule (34.4%). The 30-DM was 17.5%. For those who died in the first month the median survival was 17 days. Factors with a significant impact on 30-DM were: male gender (p < 0.0001); Eastern Cooperative Oncology Group (ECOG) Performance Status (PS) of 2–3 (p = 0.0001); visceral metastases (p = 0.0353); lung, gastrointestinal or urinary tract primary tumors (p = 0.016); and single dose RT (p = <0.0001). In the multivariate analysis, male gender, ECOG PS 2–3, gastrointestinal and lung cancer were found to be independent factors related to 30-DM. Conclusion: Our 30-DM is similar to previous studies. We have found four clinical factors related to 30-DM of which ECOG was the most strongly associated. This data may help to identify terminally ill patients with poor prognosis in order to avoid unnecessary treatments