Ablation and transmission of thin solid targets irradiated by intense extreme ultraviolet laser radiation

The interaction of an extreme ultraviolet (EUV) laser beam with a parylene foil was studied by experiments and simulation. A single EUV laser pulse of nanosecond duration focused to an intensity of 3 × 1010 W cm−2 perforated micrometer thick targets. The same laser pulse was simultaneously used to diagnose the interaction by a transmission measurement. A combination of 2-dimensional radiation-hydrodynamic and diffraction calculations was used to model the ablation, leading to good agreement with experiment. This theoretical approach allows predictive modelling of the interaction with matter of intense EUV beams over a broad range of parameters

Cross-Sectoral and Multilevel Dimensions of Risk and Resilience Management in Urban Areas Enabled by Geospatial Data Processing

The growing complexity of cities and the unprecedented pace of urbanisation create exposure and vulnerabilities to extreme events and crises that are difficult to manage and plan for as widely acknowledged by the existing literature. In this paper, three main challenges to be tackled are identified based on the selected literature according to the interpretation of the authors based on extended research in the field. Those challenges relate to the multi-risk environment characterising many contemporary cities, the need to overcome sectoral approaches towards increased alignment of emergency and spatial planning at different scales, and the opportunities that derive from integrated risk and resilience management. Such challenges are evidenced in the Pozzuoli case study, a densely inhabited municipality of the metropolitan city of Naples, placed into a volcanic caldera, that has been analysed in the light of the above challenges for an extended period of time of about fifty years. The in-depth assessment of the quality of urban development has been enabled by geospatial data management. Advanced geospatial information systems are not only instrumental in depicting the history of urban development in the period of consideration but also as an enabler to tackle the above-mentioned challenges. In fact, such systems permit a much more dynamic and updatable assessment of multirisk conditions and provide the basis for shared knowledge among the large number of stakeholders that are responsible for different sectoral and comprehensive urban and risk-related plans

Temporal dynamics of semiconductor lasers with optical feedback

Includes bibliographical references (page 5539).We measure the temporal evolution of the intensity of an edge emitting semiconductor laser with delayed optical feedback for time spans ranging from 4.5 to 65 ns with a time resolution from 16to 230 ps, respectively. Spectrally resolved streak camera measurements show that the fast pulsing of the total intensity is a consequence of the time delay and multimode operation of the laser. We experimentally observe that the instabilities at low frequency are generated by the interaction among different modes of the laser

Spatio-temporal dynamics in vertical cavity surface emitting lasers excited by fast electrical pulses

Includes bibliographical references (pages 320-321).We have measured the time average spatial intensity distribution and the spatio-temporal evolution of the spectrally resolved radiation emitted from broad-area vertical cavity surface emitting lasers (VCSEL) when pumped by a fast current pulse. We show that an intrinsic symmetry break exists due to geometrical asymmetry of the device structure and that the frequency separation between different modes allows the evaluation of the asymmetry factor. The space-time behavior shows the appearance of higher-order modes coexisting or alternating in time. The dynamical behavior shows a chirping infrequency

Volume extreme ultraviolet holographic imaging with numerical optical sectioning

Includes bibliographical references (pages 10622-10623).Three dimensional images were obtained using a single high numerical aperture hologram recorded in a high resolution photoresist with a table top λ = 46.9 nm laser. Gabor holograms were numerically reconstructed over a range of image planes by sweeping the propagation distance in the numerical reconstruction algorithm, allowing numerical optical sectioning. A robust three dimension image of a test object was obtained with numerical optical sectioning, providing a longitudinal resolution of approximately 2 μm and a lateral resolution of 164 nm

Sub 400 nm spatial resolution extreme ultraviolet holography with a table top laser

Includes bibliographical references (pages 9636-9637).We report sub-400 nm spatial resolution with Gabor holography obtained using a highly coherent table top 46.9 nm laser. The hologram was recorded in high resolution photoresist and subsequently digitized with an atomic force microscope. The final image was numerically reconstructed with a Fresnel propagator. Optimal reconstruction parameters and quantification of spatial resolution were obtained with a wavelet analysis and image correlation

UVSSA and USP7, a new couple in transcription-coupled DNA repair

Transcription-coupled nucleotide excision repair (TC-NER) specifically removes transcription-blocking lesions from our genome. Defects in this pathway are associated with two human disorders: Cockayne syndrome (CS) and UV-sensitive syndrome (UVSS). Despite a similar cellular defect in the UV DNA damage response, patients with these syndromes exhibit strikingly distinct symptoms; CS patients display severe developmental, neurological, and premature aging features, whereas the phenotype of UVSS patients is mostly restricted to UV hypersensitivity. The exact molecular mechanism behind these clinical differences is still unknown; however, they might be explained by additional functions of CS proteins beyond TC-NER. A short overview of the current hypotheses addressing possible molecular mechanisms and the proteins involved are presented in this review. In addition, we will focus on two new players involved in TC-NER which were recently identified: UV-stimulated scaffold protein A (UVSSA) and ubiquitin-specific protease 7 (USP7). UVSSA has been found to be the causative gene for UVSS and, together with USP7, is implicated in regulating TC-NER activity. We will discuss the function of UVSSA and USP7 and how the discovery of these proteins contributes to a better understanding of the molecular mechanisms underlying the clinical differences between UVSS and the more severe CS

Dairy Calcium versus Calcium from other natural foods and added

Objetivos: determinar qué cantidades de alimentos vegetales, naturales e industrializados, igualan el contenido de calcio de una porción de leche, e identificar las variaciones en macronutrientes y energía. Resultados y Comentarios: las porciones de alimentos a consumir son muy superiores a las que estamos habituados produciéndose además un aumento sustancial en el aporte calóricoObjectives: determinate what amounts of vegetables, natural and processed foods, equal the calcium content of a serving of milk and identify changes in macronutrients and energy. Results and Comments: the food portion to consume is far superior we are accustomed, producing a substantial increase in calorie intake

Methodological framework for an integrated multi-scale vulnerability and resilience assessment

The deliverable illustrates the methodological framework to assess vulnerability and resilience across different temporal and spatial scales, acknowledging the different domains where the latter may manifest, and in particular in the natural and the built environment, allocating a large importance to the so called “critical infrastructures”, in social and economic systems. A set of four matrices has been developed to identify what aspects should be looked at before the impact, that is to say what shows the potential ability or inability to cope with an extreme; at the impact, addressing in particular the capacity (or incapacity) to sustain various types of stresses (in the form of acceleration, pressure, heat…); in the time immediately after the impact, as the ability (or inability) to suffer losses and still continue functioning; and in the longer term of recovery, as the capacity to find a new state of equilibrium in which the fragilities manifested during and after the impact are addressed. Developing the framework, a particular attention has been paid to the relationships among systems within the same matrix and among matrices, across spatial and temporal scales. A set of matrices has been developed for different natural hazards, including in particular landslides and floods, trying to include as much as possible what past cases, the international literature and prior experience of involved partners have indicated as relevant parameters and factors to look at. In this regard, the project builds on the state of the art, embedding what has been learned until now in terms of response capacity to a variety of stresses and in the meantime identifying gaps to be addressed by future research