What\u27s Being Sold and To What End? A Content Analysis of College Viewbooks

The article analyzes the content of college viewbooks, which are designed to entice students to enroll in the universities that they represent. Viewbooks are considered a very important medium by which institutions communicate with prospective students. The authors look at the content of a wide variety of college viewbooks, examining common themes, the ways in which themes vary by institutional type and control, and what messages are communicated to students about the academic purposes of higher education. Viewbooks are an important medium for enticing students to apply to colleges. But what messages are conveyed in them? This study offers an in-depth examination of 48 viewbooks using content analysis. The findings point to the predominance of a highly privatized conception of a college education

Toward a Clearer Understanding of Privatization

The trend toward privatization in higher education is clearly accelerating, as evidenced in both the scholarly and popular presses. It remains unclear whether governments cannot, or choose not to, provide sufficient resources to public postsecondary education, but intelligence points to a myriad of possible points of contention. For instance, the subprime mortgage crisis, downturns on Wall Street, declining state tax bases, and other recently emerging trends suggest little relief is in sight. Furthermore, higher education and the states most likely won\u27t be relieved by other long-term fiscal pressures. K-12 education and Medicare are frequently factors behind funding shortages. State policy continues to encourage competition not only with private institutions but also with other public institutions on a mounting set of issues. For example, Ohio created a program in which its public institutions compete for a $150 million pot of research funding (Richards, 2007). Institutions continue to compete for students and their mi tion dollars, particularly those students who have the means to pay or to use their state-based merit dollars. The competition for students will be especially acute in states, such as Colorado, that have adopted a voucher-style funding structure. Tuition and vouchers, not state block grants, have become an increasingly important source of revenue for some public research universities. States too are recognizing the funding problem and realize that if they cannot provide the resources for their institutions, they should allow them the autonomy and flexibility to set and keep their tuition and to compete for students, investments, and faculty with little state intervention

There's No "I" in "Team": Lessons from Athletics on Community Building

This is the publisher's version, also available electronically from http://muse.jhu.edu/journals/review_of_higher_education/v024/24.4wolf-wendel.html.No abstract is available for this item

How Much Difference is too Much Difference? Perceptions of Gay Men and Lesbians in Intercollegiate Athletics

This is the publisher's version, copyright by Johns Hopkins University Press.No abstract is available for this item

A Response to the Rejoinder

This is the publisher's version, also available electronically from http://muse.jhu.edu/journals/review_of_higher_education/v026/26.4morphew.html.No abstract is available for this item

Residential Proximity to Freeways is Associated with Uncontrolled Asthma in Inner-City Hispanic Children and Adolescents

Background. Proximity to heavy traffic has been linked to increased asthma severity. However, it is unknown whether exposure to heavy traffic is associated with the ability to maintain asthma control. Objectives. This study examines whether exposure to heavy traffic is associated with the ability to maintain asthma control in inner-city children. Methods. 756 inner-city asthmatic Hispanic children were followed for one year in a pediatric asthma management program (Breathmobile). At each scheduled visit, asthma specialist tracked patients' asthma severity and managed their asthma based on the NAEPP guidelines. The patients' residential distance from the nearest freeway was calculated based on residential address at study entry. Distance to nearest freeway was used as a surrogate marker for high exposure from traffic-related air pollutants. Results. Patients who lived near a freeway were significantly more likely to have asthma that was not well controlled (P = .03). Patients with intermittent and mild baseline severity have a two-fold increased risk of having asthma that is uncontrolled if they lived <2 miles from a freeway (OR = 2.2, P = .04). Conclusion. In children with asthma, residential proximity to freeways is associated with uncontrolled asthma

The Sigma Class glutathione transferase from the liver fluke Fasciola hepatica

BACKGROUND: Liver fluke infection of livestock causes economic losses of over US$ 3 billion worldwide per annum. The disease is increasing in livestock worldwide and is a re-emerging human disease. There are currently no commercial vaccines, and only one drug with significant efficacy against adult worms and juveniles. A liver fluke vaccine is deemed essential as short-lived chemotherapy, which is prone to resistance, is an unsustainable option in both developed and developing countries. Protein superfamilies have provided a number of leading liver fluke vaccine candidates. A new form of glutathione transferase (GST) family, Sigma class GST, closely related to a leading Schistosome vaccine candidate (Sm28), has previously been revealed by proteomics in the liver fluke but not functionally characterised. METHODOLOGY/PRINCIPAL FINDINGS: In this manuscript we show that a purified recombinant form of the F. hepatica Sigma class GST possesses prostaglandin synthase activity and influences activity of host immune cells. Immunocytochemistry and western blotting have shown the protein is present near the surface of the fluke and expressed in eggs and newly excysted juveniles, and present in the excretory/secretory fraction of adults. We have assessed the potential to use F. hepatica Sigma class GST as a vaccine in a goat-based vaccine trial. No significant reduction of worm burden was found but we show significant reduction in the pathology normally associated with liver fluke infection. CONCLUSIONS/SIGNIFICANCE: We have shown that F. hepatica Sigma class GST has likely multi-functional roles in the host-parasite interaction from general detoxification and bile acid sequestration to PGD synthase activity

Evidence of Immune Modulators in the Secretome of the Equine Tapeworm Anoplocephala perfoliata

Anoplocephala perfoliata is a neglected gastro-intestinal tapeworm, commonly infecting horses worldwide. Molecular investigation of A. perfoliata is hampered by a lack of tools to better understand the host–parasite interface. This interface is likely influenced by parasite derived immune modulators released in the secretome as free proteins or components of extracellular vesicles (EVs). Therefore, adult RNA was sequenced and de novo assembled to generate the first A. perfoliata transcriptome. In addition, excretory secretory products (ESP) from adult A. perfoliata were collected and EVs isolated using size exclusion chromatography, prior to proteomic analysis of the EVs, the EV surface and EV depleted ESP. Transcriptome analysis revealed 454 sequences homologous to known helminth immune modulators including two novel Sigma class GSTs, five α-HSP90s, and three α-enolases with isoforms of all three observed within the proteomic analysis of the secretome. Furthermore, secretome proteomics identified common helminth proteins across each sample with known EV markers, such as annexins and tetraspanins, observed in EV fractions. Importantly, 49 of the 454 putative immune modulators were identified across the secretome proteomics contained within and on the surface of EVs in addition to those identified in free ESP. This work provides the molecular tools for A. perfoliata to reveal key players in the host–parasite interaction within the horse host

Proteomics and in silico approaches to extend understanding of the glutathione transferase superfamily of the tropical liver fluke Fasciola gigantica

Fasciolosis is an important foodborne, zoonotic disease of livestock and humans, with global annual health and economic losses estimated at several billion US$. Fasciola hepatica is the major species in temperate regions, while F. gigantica dominates in the tropics. In the absence of commercially available vaccines to control fasciolosis, increasing reports of resistance to current chemotherapeutic strategies and the spread of fasciolosis into new areas, new functional genomics approaches are being used to identify potential new drug targets and vaccine candidates. The glutathione transferase (GST) superfamily is both a candidate drug and vaccine target. This study reports the identification of a putatively novel Sigma class GST, present in a water-soluble cytosol extract from the tropical liver fluke F. gigantica. The GST was cloned and expressed as an enzymically active recombinant protein. This GST shares a greater identity with the human schistosomiasis GST vaccine currently at Phase II clinical trials than previously discovered F. gigantica GSTs, stimulating interest in its immuno-protective properties. In addition, in silico analysis of the GST superfamily of both F. gigantica and F. hepatica has revealed an additional Mu class GST, Omega class GSTs, and for the first time, a Zeta class member