10,628 research outputs found
Kolmogorov-Smirnov method for the determination of signal time-shifts
A new method for the determination of electric signal time-shifts is
introduced. As the Kolmogorov-Smirnov test, it is based on the comparison of
the cumulative distribution functions of the reference signal with the test
signal. This method is very fast and thus well suited for on-line applications.
It is robust to noise and its performances in terms of precision are excellent
for time-shifts ranging from a fraction to several sample durations.
PACS. 29.40.Gx (Tracking and position-sensitive detectors), 29.30.Kv (X- and
-ray spectroscopy), 07.50.Qx (Signal processing electronics)Comment: 8 pages, 7 figure
Fast analytical methods for the correction of signal random time-shifts and application to segmented HPGe detectors
Detection systems rely more and more on on-line or off-line comparison of
detected signals with basis signals in order to determine the characteristics
of the impinging particles. Unfortunately, these comparisons are very sensitive
to the random time shifts that may alter the signal delivered by the detectors.
We present two fast algebraic methods to determine the value of the time shift
and to enhance the reliability of the comparison to the basis signals.Comment: 13 pages, 8 figure
Π‘ΠΊΡΠΈΠ½ΠΈΠ½Π³ ΡΠΊΡΡΡΠ°ΠΊΡΠΎΠ² Π»Π΅ΠΊΠ°ΡΡΡΠ²Π΅Π½Π½ΡΡ ΡΠ°ΡΡΠ΅Π½ΠΈΠΉ Π²ΠΎ ΠΡΠ΅ΡΠ½Π°ΠΌΠ΅ ΠΈ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΠ΅ ΠΈΡ ΠΊΠΎΠΌΠ±ΠΈΠ½Π°ΡΠΈΠΈ Π΄Π»Ρ ΠΏΡΠΎΡΠΈΠ»Π°ΠΊΡΠΈΠΊΠΈ ΠΈ Π»Π΅ΡΠ΅Π½ΠΈΡ ΠΏΠΎΠ΄Π°Π³ΡΡ
Objectives. The study aimed to examine the potential use of ethanol extracts of four medicinal plants to prevent and treat gout disease.Methods. An investigation of some typical compound contents such as polyphenols, flavonoids, and tannins in terms of two bioactive abilities, including anti-xanthine oxidase and antioxidant was carried out in Eclipta prostrata L., Artemisia vulgaris L., Apium graveolens L., and Piper betle L samples. Subsequently, the weight ratios of Piper betle L. and Artemisia vulgaris L. were investigated to reduce the total tannin content and get the most suitable anti-xanthine oxidase activity.Results. As well as having the highest target compound contents, Piper betle L. demonstrated the best anti-xanthine oxidase and antioxidant abilities even while its IC50 values were lower than positive control; however, its high total tannin content can cause some side effects. A mixture with a weight ratio of 1:1 of Piper betle L. and Artemisia vulgaris L. had a total tannin content half that of Piper betle L. as well as demonstrating potential anti-xanthine oxidase and antioxidant activities when IC50 was about 3.94 and 20.85 Β΅g/mL, respectively.Conclusions. Out of the four selected plants, Piper betle L. demonstrated the best potential material for preventing and treating gout disease. However, due to the high tannin content in it, a mix of Piper betle L. and Artemisia vulgaris L. at a weight ratio of 1:1 gave optimal results for application in treatment.Π¦Π΅Π»ΠΈ. ΠΠ·ΡΡΠΈΡΡ ΠΏΠΎΡΠ΅Π½ΡΠΈΠ°Π»ΡΠ½ΠΎΠ΅ ΠΈΡΠΏΠΎΠ»ΡΠ·ΠΎΠ²Π°Π½ΠΈΠ΅ ΡΡΠ°Π½ΠΎΠ»ΡΠ½ΡΡ
ΡΠΊΡΡΡΠ°ΠΊΡΠΎΠ² ΡΠ΅ΡΡΡΠ΅Ρ
Π»Π΅ΠΊΠ°ΡΡΡΠ²Π΅Π½Π½ΡΡ
ΡΠ°ΡΡΠ΅Π½ΠΈΠΉ Π΄Π»Ρ ΠΏΡΠΎΡΠΈΠ»Π°ΠΊΡΠΈΠΊΠΈ ΠΈ Π»Π΅ΡΠ΅Π½ΠΈΡ ΠΏΠΎΠ΄Π°Π³ΡΡ.ΠΠ΅ΡΠΎΠ΄Ρ. ΠΠ±ΡΠ°Π·ΡΡ ΡΠΊΠ»ΠΈΠΏΡΡ ΠΏΡΠΎΡΡΡΡΡΠΎΠΉ (Eclipta prostrata L.), ΠΏΠΎΠ»ΡΠ½ΠΈ ΠΎΠ±ΡΠΊΠ½ΠΎΠ²Π΅Π½Π½ΠΎΠΉ (Artemisia vulgaris L.), ΡΠ΅Π»ΡΠ΄Π΅ΡΠ΅Ρ ΠΏΠ°Ρ
ΡΡΠ΅Π³ΠΎ (Apium graveolens L.) ΠΈ ΠΏΠ΅ΡΡΠ° Π±Π΅ΡΠ΅Π»Ρ (Piper betle L. ) ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π»ΠΈΡΡ Ρ ΡΠΎΡΠΊΠΈ Π·ΡΠ΅Π½ΠΈΡ ΡΠΎΠ΄Π΅ΡΠΆΠ°Π½ΠΈΡ Π² Π½ΠΈΡ
ΠΏΠΎΠ»ΠΈΡΠ΅Π½ΠΎΠ»ΠΎΠ², ΡΠ»Π°Π²ΠΎΠ½ΠΎΠΈΠ΄ΠΎΠ² ΠΈ Π΄ΡΠ±ΠΈΠ»ΡΠ½ΡΡ
Π²Π΅ΡΠ΅ΡΡΠ², Π° ΡΠ°ΠΊΠΆΠ΅ Π½Π°Π»ΠΈΡΠΈΡ Π±ΠΈΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈ Π°ΠΊΡΠΈΠ²Π½ΡΡ
ΡΠ²ΠΎΠΉΡΡΠ², Π²ΠΊΠ»ΡΡΠ°Ρ Π°Π½ΡΠΈΠΊΡΠ°Π½ΡΠΈΠ½ΠΎΠΊΡΠΈΠ΄Π°Π·Π½ΡΡ ΠΈ Π°Π½ΡΠΈΠΎΠΊΡΠΈΠ΄Π°Π½ΡΠ½ΡΡ Π°ΠΊΡΠΈΠ²Π½ΠΎΡΡΡ. ΠΠ°Π»Π΅Π΅ Π±ΡΠ»ΠΈ Π½Π°ΠΉΠ΄Π΅Π½Ρ Π²Π΅ΡΠΎΠ²ΡΠ΅ ΡΠΎΠΎΡΠ½ΠΎΡΠ΅Π½ΠΈΡ Piper betle L. ΠΈ Artemisia vulgaris L., ΠΏΠΎΠ·Π²ΠΎΠ»ΡΡΡΠΈΠ΅ ΡΠ½ΠΈΠ·ΠΈΡΡ ΠΎΠ±ΡΠ΅Π΅ ΡΠΎΠ΄Π΅ΡΠΆΠ°Π½ΠΈΠ΅ ΡΠ°Π½ΠΈΠ½Π° ΠΈ ΠΏΠΎΠ»ΡΡΠΈΡΡ Π½Π°ΠΈΠ±ΠΎΠ»Π΅Π΅ ΠΏΠΎΠ΄Ρ
ΠΎΠ΄ΡΡΡΡ Π°Π½ΡΠΈΠΊΡΠ°Π½ΡΠΈΠ½ΠΎΠΊΡΠΈΠ΄Π°Π·Π½ΡΡ Π°ΠΊΡΠΈΠ²Π½ΠΎΡΡΡ.Π Π΅Π·ΡΠ»ΡΡΠ°ΡΡ. ΠΠΎΠΌΠΈΠΌΠΎ ΡΠ°ΠΌΠΎΠ³ΠΎ Π²ΡΡΠΎΠΊΠΎΠ³ΠΎ ΡΠΎΠ΄Π΅ΡΠΆΠ°Π½ΠΈΡ ΡΠ΅Π»Π΅Π²ΠΎΠ³ΠΎ ΡΠΎΠ΅Π΄ΠΈΠ½Π΅Π½ΠΈΡ, Piper betle L. ΠΏΡΠΎΠ΄Π΅ΠΌΠΎΠ½ΡΡΡΠΈΡΠΎΠ²Π°Π» Π½Π°ΠΈΠ»ΡΡΡΠΈΠ΅ Π°Π½ΡΠΈΠΊΡΠ°Π½ΡΠΈΠ½ΠΎΠΊΡΠΈΠ΄Π°Π·Π½ΡΠ΅ ΠΈ Π°Π½ΡΠΈΠΎΠΊΡΠΈΠ΄Π°Π½ΡΠ½ΡΠ΅ ΡΠ²ΠΎΠΉΡΡΠ²Π°, Π΄Π°ΠΆΠ΅ Π½Π΅ΡΠΌΠΎΡΡΡ Π½Π° ΡΠΎ, ΡΡΠΎ Π΅Π³ΠΎ Π·Π½Π°ΡΠ΅Π½ΠΈΡ IC50 Π±ΡΠ»ΠΈ Π½ΠΈΠΆΠ΅ ΠΏΠΎΠ»ΠΎΠΆΠΈΡΠ΅Π»ΡΠ½ΠΎΠ³ΠΎ ΠΊΠΎΠ½ΡΡΠΎΠ»Ρ. ΠΠ΄Π½Π°ΠΊΠΎ Π²ΡΡΠΎΠΊΠΎΠ΅ ΡΠΎΠ΄Π΅ΡΠΆΠ°Π½ΠΈΠ΅ ΠΎΠ±ΡΠ΅Π³ΠΎ ΡΠ°Π½ΠΈΠ½Π° Π² Π½Π΅ΠΌ ΠΌΠΎΠΆΠ΅Ρ Π²ΡΠ·ΡΠ²Π°ΡΡ Π½Π΅ΠΊΠΎΡΠΎΡΡΠ΅ ΠΏΠΎΠ±ΠΎΡΠ½ΡΠ΅ ΡΡΡΠ΅ΠΊΡΡ. Π‘ΠΌΠ΅ΡΡ Piper betle L. ΠΈ Artemisia vulgaris L. Ρ ΠΌΠ°ΡΡΠΎΠ²ΡΠΌ ΡΠΎΠΎΡΠ½ΠΎΡΠ΅Π½ΠΈΠ΅ΠΌ 1:1 ΠΈΠΌΠ΅Π»Π° ΠΎΠ±ΡΠ΅Π΅ ΡΠΎΠ΄Π΅ΡΠΆΠ°Π½ΠΈΠ΅ ΡΠ°Π½ΠΈΠ½Π° Π²Π΄Π²ΠΎΠ΅ ΠΌΠ΅Π½ΡΡΠ΅, ΡΠ΅ΠΌ Piper betle L., Π° ΡΠ°ΠΊΠΆΠ΅ Π΄Π΅ΠΌΠΎΠ½ΡΡΡΠΈΡΠΎΠ²Π°Π»Π° ΠΏΠΎΡΠ΅Π½ΡΠΈΠ°Π»ΡΠ½ΡΡ Π°Π½ΡΠΈΠΊΡΠ°Π½ΡΠΈΠ½ΠΎΠΊΡΠΈΠ΄Π°Π·Π½ΡΡ ΠΈ Π°Π½ΡΠΈΠΎΠΊΡΠΈΠ΄Π°Π½ΡΠ½ΡΡ Π°ΠΊΡΠΈΠ²Π½ΠΎΡΡΡ, ΠΏΡΠΈ ΡΡΠΎΠΌ IC50 ΡΠΎΡΡΠ°Π²Π»ΡΠ» ΠΎΠΊΠΎΠ»ΠΎ 3.94 ΠΈ 20.85 ΠΌΠΊΠ³/ΠΌΠ» ΡΠΎΠΎΡΠ²Π΅ΡΡΡΠ²Π΅Π½Π½ΠΎ.ΠΡΠ²ΠΎΠ΄Ρ. ΠΠ· ΡΠ΅ΡΡΡΠ΅Ρ
ΠΎΡΠΎΠ±ΡΠ°Π½Π½ΡΡ
ΡΠ°ΡΡΠ΅Π½ΠΈΠΉ Piper betle L. ΡΠ²Π»ΡΠ΅ΡΡΡ Π½Π°ΠΈΠ»ΡΡΡΠΈΠΌ ΠΏΠΎΡΠ΅Π½ΡΠΈΠ°Π»ΡΠ½ΡΠΌ ΠΌΠ°ΡΠ΅ΡΠΈΠ°Π»ΠΎΠΌ Π΄Π»Ρ ΠΏΡΠΎΡΠΈΠ»Π°ΠΊΡΠΈΠΊΠΈ ΠΈ Π»Π΅ΡΠ΅Π½ΠΈΡ ΠΏΠΎΠ΄Π°Π³ΡΡ. ΠΠ΄Π½Π°ΠΊΠΎ ΠΈΠ·-Π·Π° Π²ΡΡΠΎΠΊΠΎΠ³ΠΎ ΡΠΎΠ΄Π΅ΡΠΆΠ°Π½ΠΈΡ Π² Π½Π΅ΠΌ ΡΠ°Π½ΠΈΠ½Π° ΡΠΌΠ΅ΡΡ Piper betle L. ΠΈ Artemisia vulgaris L. Π² ΡΠΎΠΎΡΠ½ΠΎΡΠ΅Π½ΠΈΠΈ ΠΏΠΎ ΠΌΠ°ΡΡΠ΅ 1:1 Π΄Π°Π»Π° ΠΎΠΏΡΠΈΠΌΠ°Π»ΡΠ½ΡΠ΅ ΡΠ΅Π·ΡΠ»ΡΡΠ°ΡΡ Π΄Π»Ρ ΠΏΡΠΈΠΌΠ΅Π½Π΅Π½ΠΈΡ Π² Π»Π΅ΡΠ΅Π½ΠΈΠΈ
Dorsalgies : un problème en médecine du travail : apports du réseau de surveillance épidémiologique des troubles musculo-squelettiques dans les Pays de la Loire
Absorbing boundary conditions for the Westervelt equation
The focus of this work is on the construction of a family of nonlinear
absorbing boundary conditions for the Westervelt equation in one and two space
dimensions. The principal ingredient used in the design of such conditions is
pseudo-differential calculus. This approach enables to develop high order
boundary conditions in a consistent way which are typically more accurate than
their low order analogs. Under the hypothesis of small initial data, we
establish local well-posedness for the Westervelt equation with the absorbing
boundary conditions. The performed numerical experiments illustrate the
efficiency of the proposed boundary conditions for different regimes of wave
propagation
The High-Superior-Tension Technique: Evolution of Lipoabdominoplasty
Because abdominoplasty is associated with complications such as seroma and necrosis as well as epigastric bulging and a suprapubic scar located too high, the demand for this procedure is not as high as it otherwise might be. However, although these negative effects were common many years ago, their incidence has decreased dramatically with modern abdominoplastic techniques. One approach using a combination of abdominoplasty and liposuction or lipoabdominoplasty has resolved many of the problems faced with earlier techniques, offering aesthetically pleasing results and excellent reliability. The keys to successful lipoabdominoplasty, first developed as the high-superior-tension technique, are extensive liposuction, preservation of lymphatic trunks, preaponeurotic epigastric dissection, major muscle fascia plication, two high-tension paraumbilical sutures, hypogastric tension sutures, and closure of the dead spaces. The most recent updates to this technique are described in this article
Design Principles for Plasmonic Nanoparticle Devices
For all applications of plasmonics to technology it is required to tailor the
resonance to the optical system in question. This chapter gives an
understanding of the design considerations for nanoparticles needed to tune the
resonance. First the basic concepts of plasmonics are reviewed with a focus on
the physics of nanoparticles. An introduction to the finite element method is
given with emphasis on the suitability of the method to nanoplasmonic device
simulation. The effects of nanoparticle shape on the spectral position and
lineshape of the plasmonic resonance are discussed including retardation and
surface curvature effects. The most technologically important plasmonic
materials are assessed for device applicability and the importance of
substrates in light scattering is explained. Finally the application of
plasmonic nanoparticles to photovoltaic devices is discussed.Comment: 29 pages, 15 figures, part of an edited book: "Linear and Non-Linear
Nanoplasmonics
Π‘ΠΊΡΠΈΠ½ΠΈΠ½Π³ ΡΠΊΡΡΡΠ°ΠΊΡΠΎΠ² Π»Π΅ΠΊΠ°ΡΡΡΠ²Π΅Π½Π½ΡΡ ΡΠ°ΡΡΠ΅Π½ΠΈΠΉ Π½Π° ΠΈΠ½Π³ΠΈΠ±ΠΈΡΡΡΡΡΡ Π°ΠΊΡΠΈΠ²Π½ΠΎΡΡΡ ΠΊΡΠ°Π½ΡΠΈΠ½ΠΎΠΊΡΠΈΠ΄Π°Π·Ρ
Objectives. The study aimed to test the ethanol extracts of ten medicinal plants for xanthine oxidase inhibitory activity.Methods. The degree of xanthine oxidase inhibitory activity was determined by measuring the absorbance spectrophotometrically at 290 nm, which is associated with uric acid formation. The selected medicinal plants included Piper lolot C.DC. (Piperaceae), Pandanus amaryllifolius R.(Pandanaceae), Brassica juncea L. (Brassicaceae), Piper betle L. (Piperaceae), Perilla frutescens L. (Lamiaceae), Anacardium occidentale L. (Anacardiaceae), Polygonum barbatum L. (Polygonaceae), Artocarpus Altilis P. (Moraceae), Vitex negundo L. (Verbenaceae), Annona squamosal L. (Annonaceae), which were selected based on folk medicine.Results. The results showed that the Piper betle L. has a strong ability to inhibit xanthine oxidase with an IC50 value of up to 1.18 ΞΌg/mL, compared to allopurinol 1.57 ΞΌg/mL. Different parts of Piper betle L. were compared and the leaves of Piper betle L. showed the best value for xanthine oxidase inhibitory and antioxidant activity.Conclusions. Piper betle L. showed the best potential for inhibition of xanthine oxidase among ten medicinal plants. Piper betle L. leaf extract showed strong xanthine oxidase inhibitory and antioxidant activity, compared to the whole plant, and the stem extract, which promises to be applied in the treatment of gout.Π¦Π΅Π»ΠΈ. ΠΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΠ΅ Π±ΡΠ»ΠΎ Π½Π°ΠΏΡΠ°Π²Π»Π΅Π½ΠΎ Π½Π° ΠΏΡΠΎΠ²Π΅ΡΠΊΡ ΡΡΠ°Π½ΠΎΠ»ΡΠ½ΡΡ
ΡΠΊΡΡΡΠ°ΠΊΡΠΎΠ² Π΄Π΅ΡΡΡΠΈ Π»Π΅ΠΊΠ°ΡΡΡΠ²Π΅Π½Π½ΡΡ
ΡΠ°ΡΡΠ΅Π½ΠΈΠΉ Π½Π° ΠΈΠ½Π³ΠΈΠ±ΠΈΡΠΎΡΠ½ΡΡ Π°ΠΊΡΠΈΠ²Π½ΠΎΡΡΡ ΠΊΡΠ°Π½ΡΠΈΠ½ΠΎΠΊΡΠΈΠ΄ Π°Π·Ρ.ΠΠ΅ΡΠΎΠ΄Ρ. Π‘ΡΠ΅ΠΏΠ΅Π½Ρ ΠΈΠ½Π³ΠΈΠ±ΠΈΡΡΡΡΠ΅ΠΉ Π°ΠΊΡΠΈΠ²Π½ΠΎΡΡΠΈ ΠΊΡΠ°Π½ΡΠΈΠ½ΠΎΠΊΡΠΈΠ΄Π°Π·Ρ ΠΎΠΏΡΠ΅Π΄Π΅Π»ΡΠ»ΠΈ ΠΏΡΡΠ΅ΠΌ ΡΠΏΠ΅ΠΊΡΡΠΎΡΠΎΡΠΎΠΌΠ΅ΡΡΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ ΠΈΠ·ΠΌΠ΅ΡΠ΅Π½ΠΈΡ ΠΏΠΎΠ³Π»ΠΎΡΠ΅Π½ΠΈΡ ΠΏΡΠΈ 290 Π½ΠΌ, Π²ΡΠ·ΡΠ²Π°Π΅ΠΌΠΎΠ³ΠΎ ΠΎΠ±ΡΠ°Π·ΠΎΠ²Π°Π½ΠΈΠ΅ΠΌ ΠΌΠΎΡΠ΅Π²ΠΎΠΉ ΠΊΠΈΡΠ»ΠΎΡΡ. Π ΡΠΎΡΡΠ°Π² ΠΎΡΠΎΠ±ΡΠ°Π½Π½ΡΡ
Π»Π΅ΠΊΠ°ΡΡΡΠ²Π΅Π½Π½ΡΡ
ΡΠ°ΡΡΠ΅Π½ΠΈΠΉ Π²ΠΎΡΠ»ΠΈ ΠΏΠ΅ΡΠ΅Ρ-Π»ΠΎΠ»ΠΎΡ (Piperaceae), ΠΏΠ°Π½Π΄Π°Π½ (Pandanaceae), Π³ΠΎΡΡΠΈΡΠ° ΡΠ°ΡΠ΅ΠΏΡΡΠΊΠ°Ρ (Brassicaceae), Π±Π΅ΡΠ΅Π»Ρ (Piperaceae), ΠΏΠ΅ΡΠΈΠ»Π»Π° ΠΎΠ±ΡΠΊΠ½ΠΎΠ²Π΅Π½Π½Π°Ρ (Lamiaceae), ΠΊΠ΅ΡΡΡ (Anacardiaceae), ΠΊΠΎΠ½ΠΎΠΏΠ»Ρ (Polygonaceae), Ρ
Π»Π΅Π±Π½ΠΎΠ΅ Π΄Π΅ΡΠ΅Π²ΠΎ (Moraceae), ΠΏΡΡΡΠ½ΡΠΊ ΠΊΠΈΡΠ°ΠΉΡΠΊΠΈΠΉ (Verbenaceae), ΡΠ°Ρ
Π°ΡΠ½ΠΎΠ΅ ΡΠ±Π»ΠΎΠΊΠΎ (Annonaceae), ΠΎΡΠΎΠ±ΡΠ°Π½Π½ΡΠ΅ Π½Π° ΠΎΡΠ½ΠΎΠ²Π΅ ΠΈΡ
ΠΏΡΠΈΠΌΠ΅Π½Π΅Π½ΠΈΡ Π² Π½Π°ΡΠΎΠ΄ Π½ΠΎΠΉ ΠΌΠ΅Π΄ΠΈΡΠΈΠ½Π΅.Π Π΅Π·ΡΠ»ΡΡΠ°ΡΡ. Π Π΅Π·ΡΠ»ΡΡΠ°ΡΡ ΠΏΠΎΠΊΠ°Π·Π°Π»ΠΈ, ΡΡΠΎ Π±Π΅ΡΠ΅Π»Ρ ΠΎΠ±Π»Π°Π΄Π°Π΅Ρ ΡΠΈΠ»ΡΠ½ΠΎΠΉ ΡΠΏΠΎΡΠΎΠ±Π½ΠΎΡΡΡΡ ΠΈΠ½Π³ΠΈΠ±ΠΈΡΠΎΠ²Π°ΡΡ ΠΊΡΠ°Π½ΡΠΈΠ½ΠΎΠΊΡΠΈΠ΄Π°Π·Ρ ΡΠΎ Π·Π½Π°ΡΠ΅Π½ΠΈΠ΅ΠΌ IC50 Π΄ΠΎ 1.18 ΠΌΠΊΠ³/ΠΌΠ» ΠΏΠΎ ΡΡΠ°Π²Π½Π΅Π½ΠΈΡ Ρ Π°Π»Π»ΠΎΠΏΡΡΠΈΠ½ΠΎΠ»ΠΎΠΌ 1.57 ΠΌΠΊΠ³/ΠΌΠ». ΠΡΠ»ΠΈ ΠΏΡΠΎΠ²Π΅Π΄Π΅Π½Ρ ΡΡΠ°Π²Π½Π΅Π½ΠΈΡ ΡΠ°Π·Π»ΠΈΡΠ½ΡΡ
ΡΠ°ΡΡΠ΅ΠΉ Π±Π΅ΡΠ΅Π»Ρ, ΠΈ Π»ΠΈΡΡΡΡ Π±Π΅ΡΠ΅Π»Ρ ΠΏΠΎΠΊΠ°Π·Π°Π»ΠΈ Π½Π°ΠΈΠ»ΡΡΡΠΈΠ΅ ΠΏΠΎΠΊΠ°Π·Π°ΡΠ΅Π»ΠΈ ΠΈΠ½Π³ΠΈΠ±ΠΈΡΠΎΠ²Π°Π½ΠΈΡ ΠΊΡΠ°Π½ΡΠΈΠ½ΠΎΠΊΡΠΈΠ΄Π°Π·Ρ ΠΈ Π°Π½ΡΠΈΠΎΠΊΡΠΈΠ΄Π°Π½ΡΠ½ΠΎΠΉ Π°ΠΊΡΠΈΠ²Π½ΠΎΡΡΠΈ.ΠΡΠ²ΠΎΠ΄Ρ. ΠΠ΅ΡΠ΅Π»Ρ ΠΏΠΎΠΊΠ°Π·Π°Π» Π»ΡΡΡΠΈΠΉ ΠΏΠΎΡΠ΅Π½ΡΠΈΠ°Π» ΠΈΠ½Π³ΠΈΠ±ΠΈΡΠΎΠ²Π°Π½ΠΈΡ ΠΊΡΠ°Π½ΡΠΈΠ½ΠΎΠΊΡΠΈΠ΄Π°Π·Ρ ΡΡΠ΅Π΄ΠΈ Π΄Π΅ΡΡΡΠΈ Π»Π΅ΠΊΠ°ΡΡΡΠ²Π΅Π½Π½ΡΡ
ΡΠ°ΡΡΠ΅Π½ΠΈΠΉ. ΠΠΊΡΡΡΠ°ΠΊΡ Π»ΠΈΡΡΡΠ΅Π² Π±Π΅ΡΠ΅Π»Ρ ΠΏΠΎΠΊΠ°Π·Π°Π» ΡΠΈΠ»ΡΠ½ΠΎΠ΅ ΠΏΠΎΠ΄Π°Π²Π»Π΅Π½ΠΈΠ΅ ΠΊΡΠ°Π½ΡΠΈΠ½ΠΎΠΊΡΠΈΠ΄Π°Π·Ρ ΠΈ Π°Π½ΡΠΈΠΎΠΊΡΠΈΠ΄Π°Π½ΡΠ½ΡΡ Π°ΠΊΡΠΈΠ²Π½ΠΎΡΡΡ ΠΏΠΎ ΡΡΠ°Π²Π½Π΅Π½ΠΈΡ Ρ ΡΠ΅Π»ΡΠΌ ΡΠ°ΡΡΠ΅Π½ΠΈΠ΅ΠΌ ΠΈ ΡΠΊΡΡΡΠ°ΠΊΡΠΎΠΌ ΡΡΠ΅Π±Π»Ρ, ΠΊΠΎΡΠΎΡΡΠ΅ ΠΏΡΠΈΠΌΠ΅Π½ΡΡΡΡΡ ΠΏΡΠΈ Π»Π΅ΡΠ΅Π½ΠΈΠΈ ΠΏΠΎΠ΄Π°Π³ΡΡ
Teknik Proteksi Silang Untuk Pengendalian CMV Pada Krisan
. Rahardjo, I.B., E. Diningsih, and Y. Sulyo. 2008. Cross Protection Technique for Controlling CMV on Chrysanthemum. One of viru s attack chry santhemum is CMV. The alternative to control CMV is the use of vacc ine CARNA 5. The objective of the experiment was to test the cr oss protection tech nique for controlling of CMV on several chry santhemum varieties. The experiment was conduc ted in Virology Laboratory of Indonesian Ornamental Plant Research Institute (IOPRI) in Segu nung, Pacet, Cianjur , West Java, from Augu st to December 2004, using a RC BD split-plot design with 3 replications. The main plot was 5 chry santhemum varieties of White Reagent, Town Talk, Dark Fiji, Stroika, and Revert. The subplot was treatments of vacc ine and CMV, i.e. without vacc ine and CMV, CMV only, vacc ine only, and both vacc ine and CMV. The results of the experiment showed that CARNA 5 vacc ine was able to protect chry santhemum varieties of White Reagent, Town Talk, Dark Fiji, Stroika, and Revert from CMV with normal plant growth and produced good flower quality
ΠΠΏΡΠΈΠΌΠΈΠ·Π°ΡΠΈΡ ΠΎΠ±ΡΠ΅Π³ΠΎ ΡΠΎΠ΄Π΅ΡΠΆΠ°Π½ΠΈΡ ΡΠ»Π°Π²ΠΎΠ½ΠΎΠΈΠ΄ΠΎΠ² Π² ΡΠΏΠΈΡΡΠΎΠ²ΠΎΠΌ ΡΠΊΡΡΡΠ°ΠΊΡΠ΅ Persicaria pulchra (Bl.) SojΓ‘k Π΄Π»Ρ ΠΈΠ½Π³ΠΈΠ±ΠΈΡΠΎΠ²Π°Π½ΠΈΡ ΡΠ΅ΡΠΌΠ΅Π½ΡΠ° Ξ±-Π³Π»ΡΠΊΠΎΠ·ΠΈΠ΄Π°Π·Ρ
Objectives.Β There has been a rapid increase in the number of diabetic patients since the past few decades in developed and developing countries. This rapid increase is accompanied by alarming costs of treatment. Ξ±-Glucosidase inhibitors are one of the most effective drugs employed for the reduction of postprandial hyperglycemia to manage Type 2 diabetes mellitus. Additionally, flavonoids, a group of natural substances, which are widely distributed in plants and possess variable phenolic structures, exhibit outstanding hypoglycemic activity and are considered as potential Ξ±-glucosidase inhibitors. In Vietnam, Persicaria pulchra (Bl.) SojΓ‘k (P. pulchra) is employed in traditional medications. It possesses high flavonoid contents and its anti-diabetes ability has been hypothesized, although it has attracted less attention for investigation. Hence, the aim of this study is to optimize the condition of the P. pulchra extract to obtain the highest total flavonoid content and measure the bioactivities of P. pulchra, such as the anti-Ξ±-glucosidase and antioxidant activities.Methods.Β The effects of the extracting conditions, including the temperature, extraction time, liquid-to-solid ratio (LSR), and ethanol (C2H5OH) concentration, on the total flavonoid content are investigated via experiments and analyzed by the response surface methodology (RSM). Concurrently, the optimal extraction also determines the anti-Ξ±-glucosidase and antioxidant activities.Results.Β The optimal extraction condition for the highest flavonoid content (530 mg quercetin/g) is determined in 60 min, at 53Β°C, with LSR of 9.46 g/g and C2H5OH concentration of 62%. Moreover, the optimal plant extract exhibits good Ξ±-glucosidase inhibition with a half-maximal inhibitory concentration (IC50) of 22.67 mg/mL, compared to the positive control (acarbose β7.77 g/mL). Additionally, P. pulchra is proposed to be a potential antioxidant with an IC50 of ~12.68 Β΅g/mL.Conclusions.Β The study confirmed the optimal extraction condition of P. pulchra that will obtain the highest total flavonoid content and revealed the potentials of P. pulchra in Ξ±-glucosidase inhibition and antioxidation.Π¦Π΅Π»ΠΈ. Π ΠΏΠΎΡΠ»Π΅Π΄Π½ΠΈΠ΅ Π΄Π΅ΡΡΡΠΈΠ»Π΅ΡΠΈΡ Π² ΡΠ°Π·Π²ΠΈΡΡΡ
ΠΈ ΡΠ°Π·Π²ΠΈΠ²Π°ΡΡΠΈΡ
ΡΡ ΡΡΡΠ°Π½Π°Ρ
Π½Π°Π±Π»ΡΠ΄Π°Π΅ΡΡΡ Π±ΡΡΡΡΡΠΉ ΡΠΎΡΡ ΡΠΈΡΠ»Π° Π±ΠΎΠ»ΡΠ½ΡΡ
Π΄ΠΈΠ°Π±Π΅ΡΠΎΠΌ, ΠΊΠΎΡΠΎΡΡΠΉ ΡΠΎΠΏΡΠΎΠ²ΠΎΠΆΠ΄Π°Π΅ΡΡΡ ΡΠΎΡΡΠΎΠΌ ΡΡΠΎΠΈΠΌΠΎΡΡΠΈ Π»Π΅ΡΠ΅Π½ΠΈΡ. ΠΠ½Π³ΠΈΠ±ΠΈΡΠΎΡΡ Ξ±-Π³Π»ΡΠΊΠΎΠ·ΠΈΠ΄Π°Π·Ρ ΡΠ²Π»ΡΡΡΡΡ ΠΎΠ΄Π½ΠΈΠΌ ΠΈΠ· Π½Π°ΠΈΠ±ΠΎΠ»Π΅Π΅ ΡΡΡΠ΅ΠΊΡΠΈΠ²Π½ΡΡ
ΠΏΡΠ΅ΠΏΠ°ΡΠ°ΡΠΎΠ², ΠΏΡΠΈΠΌΠ΅Π½ΡΠ΅ΠΌΡΡ
Π΄Π»Ρ ΡΠ½ΠΈΠΆΠ΅Π½ΠΈΡ ΠΏΠΎΡΡΠΏΡΠ°Π½Π΄ΠΈΠ°Π»ΡΠ½ΠΎΠΉ Π³ΠΈΠΏΠ΅ΡΠ³Π»ΠΈΠΊΠ΅ΠΌΠΈΠΈ ΠΏΡΠΈ Π»Π΅ΡΠ΅Π½ΠΈΠΈ ΡΠ°Ρ
Π°ΡΠ½ΠΎΠ³ΠΎ Π΄ΠΈΠ°Π±Π΅ΡΠ° 2 ΡΠΈΠΏΠ°. ΠΡΠΎΠΌΠ΅ ΡΠΎΠ³ΠΎ, ΡΠ»Π°Π²ΠΎΠ½ΠΎΠΈΠ΄Ρ, Π³ΡΡΠΏΠΏΠ° ΠΏΡΠΈΡΠΎΠ΄Π½ΡΡ
Π²Π΅ΡΠ΅ΡΡΠ², ΡΠΈΡΠΎΠΊΠΎ ΡΠ°ΡΠΏΡΠΎΡΡΡΠ°Π½Π΅Π½Π½ΡΡ
Π² ΡΠ°ΡΡΠ΅Π½ΠΈΡΡ
ΠΈ ΡΠΎΠ΄Π΅ΡΠΆΠ°ΡΠΈΡ
ΡΠ°Π·Π»ΠΈΡΠ½ΡΠ΅ ΠΏΡΠΎΠΈΠ·Π²ΠΎΠ΄Π½ΡΠ΅ ΡΠ΅Π½ΠΎΠ»Π°, ΠΏΡΠΎΡΠ²Π»ΡΡΡ Π·Π½Π°ΡΠΈΡΠ΅Π»ΡΠ½ΡΡ Π³ΠΈΠΏΠΎΠ³Π»ΠΈΠΊΠ΅ΠΌΠΈΡΠ΅ΡΠΊΡΡ Π°ΠΊΡΠΈΠ²Π½ΠΎΡΡΡ ΠΈ ΠΌΠΎΠ³ΡΡ ΡΠ»ΡΠΆΠΈΡΡ ΠΏΠΎΡΠ΅Π½ΡΠΈΠ°Π»ΡΠ½ΡΠΌΠΈ ΠΈΠ½Π³ΠΈΠ±ΠΈΡΠΎΡΠ°ΠΌΠΈ Ξ±-Π³Π»ΡΠΊΠΎΠ·ΠΈΠ΄Π°Π·Ρ. ΠΠΎ ΠΡΠ΅ΡΠ½Π°ΠΌΠ΅ Persicaria pulchra (Bl.) SojΓ‘k (P. pulchra) ΠΈΡΠΏΠΎΠ»ΡΠ·ΡΠ΅ΡΡΡ Π² Π½Π°ΡΠΎΠ΄Π½ΠΎΠΉ ΠΌΠ΅Π΄ΠΈΡΠΈΠ½Π΅. ΠΠ½ ΠΎΠ±Π»Π°Π΄Π°Π΅Ρ Π²ΡΡΠΎΠΊΠΈΠΌ ΡΠΎΠ΄Π΅ΡΠΆΠ°Π½ΠΈΠ΅ΠΌ ΡΠ»Π°Π²ΠΎΠ½ΠΎΠΈΠ΄ΠΎΠ² ΠΈ, ΠΏΡΠ΅Π΄ΠΏΠΎΠ»ΠΎΠΆΠΈΡΠ΅Π»ΡΠ½ΠΎ, ΠΏΡΠΎΡΠΈΠ²ΠΎΠ΄ΠΈΠ°Π±Π΅ΡΠΈΡΠ΅ΡΠΊΠΈΠΌΠΈ ΡΠ²ΠΎΠΉΡΡΠ²Π°ΠΌΠΈ, Ρ
ΠΎΡΡ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ ΠΌΠ°Π»ΠΎ. Π’Π°ΠΊΠΈΠΌ ΠΎΠ±ΡΠ°Π·ΠΎΠΌ, ΡΠ΅Π»ΡΡ Π½Π°ΡΡΠΎΡΡΠ΅Π³ΠΎ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ ΡΠ²Π»ΡΠ΅ΡΡΡ ΠΎΠΏΡΠΈΠΌΠΈΠ·Π°ΡΠΈΡ ΡΠΊΡΡΡΠ°Π³ΠΈΡΠΎΠ²Π°Π½ΠΈΡ P. pulchra Π΄Π»Ρ ΠΏΠΎΠ»ΡΡΠ΅Π½ΠΈΡ Π½Π°ΠΈΠ±ΠΎΠ»Π΅Π΅ Π²ΡΡΠΎΠΊΠΎΠ³ΠΎ ΠΎΠ±ΡΠ΅Π³ΠΎ ΡΠΎΠ΄Π΅ΡΠΆΠ°Π½ΠΈΡ ΡΠ»Π°Π²ΠΎΠ½ΠΎΠΈΠ΄ΠΎΠ², Π° ΡΠ°ΠΊΠΆΠ΅ ΠΎΠΏΡΠ΅Π΄Π΅Π»Π΅Π½ΠΈΠ΅ Π΅Π³ΠΎ Π±ΠΈΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΎΠΉ Π°ΠΊΡΠΈΠ²Π½ΠΎΡΡΠΈ β Π°Π½ΡΠΈ-Ξ±-Π³Π»ΡΠΊΠΎΠ·ΠΈΠ΄Π°Π·Π½ΠΎΠΉ ΠΈ Π°Π½ΡΠΈΠΎΠΊΡΠΈΠ΄Π°Π½ΡΠ½ΠΎΠΉ. ΠΠ΅ΡΠΎΠ΄Ρ. ΠΠΊΡΠΏΠ΅ΡΠΈΠΌΠ΅Π½ΡΠ°Π»ΡΠ½ΠΎ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΎ Π²Π»ΠΈΡΠ½ΠΈΠ΅ ΡΡΠ»ΠΎΠ²ΠΈΠΉ ΡΠΊΡΡΡΠ°Π³ΠΈΡΠΎΠ²Π°Π½ΠΈΡ, Π° ΠΈΠΌΠ΅Π½Π½ΠΎ ΡΠ΅ΠΌΠΏΠ΅ΡΠ°ΡΡΡΡ, Π²ΡΠ΅ΠΌΠ΅Π½ΠΈ ΡΠΊΡΡΡΠ°ΠΊΡΠΈΠΈ, ΡΠΎΠΎΡΠ½ΠΎΡΠ΅Π½ΠΈΡ ΠΆΠΈΠ΄ΠΊΠΎΡΡΡ : ΡΠ²Π΅ΡΠ΄ΠΎΠ΅ Π²Π΅ΡΠ΅ΡΡΠ²ΠΎ ΠΈ ΠΊΠΎΠ½ΡΠ΅Π½ΡΡΠ°ΡΠΈΠΈ ΡΡΠ°Π½ΠΎΠ»Π°, Π½Π° ΠΎΠ±ΡΠ΅Π΅ ΡΠΎΠ΄Π΅ΡΠΆΠ°Π½ΠΈΠ΅ ΡΠ»Π°Π²ΠΎΠ½ΠΎΠΈΠ΄ΠΎΠ² Ρ ΠΏΠΎΠΌΠΎΡΡΡ ΠΌΠ΅ΡΠΎΠ΄ΠΎΠ»ΠΎΠ³ΠΈΠΈ Π°Π½Π°Π»ΠΈΠ·Π° ΠΏΠΎΠ²Π΅ΡΡ
Π½ΠΎΡΡΠΈ ΠΎΡΠΊΠ»ΠΈΠΊΠ°. ΠΠΎΠΊΠ°Π·Π°Π½ΠΎ, ΡΡΠΎ ΠΎΠΏΡΠΈΠΌΠ°Π»ΡΠ½ΡΠ΅ ΡΡΠ»ΠΎΠ²ΠΈΡ ΡΠΊΡΡΡΠ°ΠΊΡΠΈΠΈ ΠΎΠΏΡΠ΅Π΄Π΅Π»ΡΡΡ Π°Π½ΡΠΈ-Ξ±-Π³Π»ΡΠΊΠΎΠ·ΠΈΠ΄Π°Π·Π½ΡΡ ΠΈ Π°Π½ΡΠΈΠΎΠΊΡΠΈΠ΄Π°Π½ΡΠ½ΡΡ Π°ΠΊΡΠΈΠ²Π½ΠΎΡΡΡ.Π Π΅Π·ΡΠ»ΡΡΠ°ΡΡ. ΠΠ°ΠΉΠ΄Π΅Π½Ρ ΠΎΠΏΡΠΈΠΌΠ°Π»ΡΠ½ΡΠ΅ ΡΡΠ»ΠΎΠ²ΠΈΡ ΡΠΊΡΡΡΠ°ΠΊΡΠΈΠΈ Π΄Π»Ρ ΠΏΠΎΠ»ΡΡΠ΅Π½ΠΈΡ ΠΌΠ°ΠΊΡΠΈΠΌΠ°Π»ΡΠ½ΠΎΠ³ΠΎ ΡΠΎΠ΄Π΅ΡΠΆΠ°Π½ΠΈΡ ΡΠ»Π°Π²ΠΎΠ½ΠΎΠΈΠ΄ΠΎΠ² (530 ΠΌΠ³ ΠΊΠ²Π΅ΡΡΠ΅ΡΠΈΠ½Π°/Π³): Π²ΡΠ΅ΠΌΡ ΡΠΊΡΡΡΠ°ΠΊΡΠΈΠΈ 60 ΠΌΠΈΠ½, ΡΠ΅ΠΌΠΏΠ΅ΡΠ°ΡΡΡΠ° 53 Β°Π‘, ΠΎΡΠ½ΠΎΡΠ΅Π½ΠΈΠ΅ ΠΆΠΈΠ΄ΠΊΠΎΡΡΡ : ΡΠ²Π΅ΡΠ΄ΠΎΠ΅ Π²Π΅ΡΠ΅ΡΡΠ²ΠΎ 9.46 Π³/Π³ ΠΈ ΠΊΠΎΠ½ΡΠ΅Π½ΡΡΠ°ΡΠΈΡ ΡΡΠ°Π½ΠΎΠ»Π° 62%. Π Π°ΡΡΠΈΡΠ΅Π»ΡΠ½ΡΠΉ ΡΠΊΡΡΡΠ°ΠΊΡ, ΠΏΠΎΠ»ΡΡΠ΅Π½Π½ΡΠΉ Π² ΠΎΠΏΡΠΈΠΌΠ°Π»ΡΠ½ΡΡ
ΡΡΠ»ΠΎΠ²ΠΈΡΡ
, ΠΏΡΠΎΡΠ²Π»ΡΠ΅Ρ Ρ
ΠΎΡΠΎΡΠ΅Π΅ ΠΈΠ½Π³ΠΈΠ±ΠΈΡΠΎΠ²Π°Π½ΠΈΠ΅ Ξ±-Π³Π»ΡΠΊΠΎΠ·ΠΈΠ΄Π°Π·Ρ Ρ ΠΊΠΎΠ½ΡΠ΅Π½ΡΡΠ°ΡΠΈΠ΅ΠΉ ΠΏΠΎΠ»ΡΠΌΠ°ΠΊΡΠΈΠΌΠ°Π»ΡΠ½ΠΎΠ³ΠΎ ΠΈΠ½Π³ΠΈΠ±ΠΈΡΠΎΠ²Π°Π½ΠΈΡ (IC50) 22.67 ΠΌΠ³/ΠΌΠ» ΠΏΠΎ ΡΡΠ°Π²Π½Π΅Π½ΠΈΡ Ρ ΠΏΠΎΠ»ΠΎΠΆΠΈΡΠ΅Π»ΡΠ½ΡΠΌ ΠΊΠΎΠ½ΡΡΠΎΠ»Π΅ΠΌ (Π°ΠΊΠ°ΡΠ±ΠΎΠ·Π° β 7.77 Π³/ΠΌΠ»). ΠΡΠ²ΠΎΠ΄Ρ. ΠΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΠ΅ Π²ΡΡΠ²ΠΈΠ»ΠΎ ΠΎΠΏΡΠΈΠΌΠ°Π»ΡΠ½ΡΠ΅ ΡΡΠ»ΠΎΠ²ΠΈΡ ΡΠΊΡΡΡΠ°ΠΊΡΠΈΠΈ P. pulchra, ΠΏΠΎΠ·Π²ΠΎΠ»ΡΡΡΠΈΠ΅ ΠΏΠΎΠ»ΡΡΠΈΡΡ Π½Π°ΠΈΠ±ΠΎΠ»Π΅Π΅ Π²ΡΡΠΎΠΊΠΎΠ΅ ΠΎΠ±ΡΠ΅Π΅ ΡΠΎΠ΄Π΅ΡΠΆΠ°Π½ΠΈΠ΅ ΡΠ»Π°Π²ΠΎΠ½ΠΎΠΈΠ΄ΠΎΠ², ΠΈ ΠΏΠΎΠ΄ΡΠ²Π΅ΡΠ΄ΠΈΠ»ΠΎ ΠΏΠ΅ΡΡΠΏΠ΅ΠΊΡΠΈΠ²Ρ ΠΏΡΠΈΠΌΠ΅Π½Π΅Π½ΠΈΡ P. pulchra Π΄Π»Ρ ΠΈΠ½Π³ΠΈΠ±ΠΈΡΠΎΠ²Π°Π½ΠΈΠΈ Ξ±-Π³Π»ΡΠΊΠΎΠ·ΠΈΠ΄Π°Π·Ρ ΠΈ Π°Π½ΡΠΈΠΎΠΊΡΠΈΠ΄Π°Π½ΡΠ½ΠΎΠ³ΠΎ ΠΎΠΊΠΈΡΠ»Π΅Π½ΠΈΡ
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