Design issues and experimental characterization of a continuously-tuned adaptive CMOS LNA

This paper presents the design implementation and experimental characterization of an adaptive Low Noise Amplifier (LNA) intended for multi-standard Radio Frequency (RF) wireless transceivers. The circuit —fabricated in a 90-nm CMOS technology— is a two-stage inductively degenerated common-source topology that combines PMOS varactors with programmable load to make the operation of the circuit continuously tunable. Practical design issues are analyzed, considering the effect of circuit parasitics associated to the chip package and integrated inductors, capacitors and varactors. Experimental measurements show a continuous tuning of NF and Sparameters within the 1.75-2.23GHz band, featuring NF19.6dB and IIP3> −9.8dBm, with a power dissipation < 23mW from a 1-V supply voltage.Ministerio de Ciencia e Innovación (FEDER) TEC2007-67247-C02-01/MICJunta de Andalucía, Consejo Regional de Innovación, ciencia y empresa TIC-253

Wireless communication, identification and sensing technologies enabling integrated logistics: a study in the harbor environment

In the last decade, integrated logistics has become an important challenge in the development of wireless communication, identification and sensing technology, due to the growing complexity of logistics processes and the increasing demand for adapting systems to new requirements. The advancement of wireless technology provides a wide range of options for the maritime container terminals. Electronic devices employed in container terminals reduce the manual effort, facilitating timely information flow and enhancing control and quality of service and decision made. In this paper, we examine the technology that can be used to support integration in harbor's logistics. In the literature, most systems have been developed to address specific needs of particular harbors, but a systematic study is missing. The purpose is to provide an overview to the reader about which technology of integrated logistics can be implemented and what remains to be addressed in the future

Performance of novel silicon n-in-p planar Pixel Sensors

The performance of novel n-in-p planar pixel detectors, designed for future upgrades of the ATLAS Pixel system is presented. The n-in-p silicon sensors technology is a promising candidate for the pixel upgrade thanks to its radiation hardness and cost effectiveness, that allow for enlarging the area instrumented with pixel detectors. The n-in-p modules presented here are composed of pixel sensors produced by CiS connected by bump-bonding to the ATLAS readout chip FE-I3. The characterization of these devices has been performed before and after irradiation up to a fluence of 5 x 10**15 1 MeV neq cm-2 . Charge collection measurements carried out with radioactive sources have proven the functioning of this technology up to these particle fluences. First results from beam test data with a 120 GeV/c pion beam at the CERN-SPS are also discussed, demonstrating a high tracking efficiency of (98.6 \pm 0.3)% and a high collected charge of about 10 ke for a device irradiated at the maximum fluence and biased at 1 kV.Comment: Preprint submitted to Nuclear Instruments and Methods A. 7 pages, 13 figure

Growth of a sinkhole in a seismic zone of the northern Apennines (Italy)

Sinkhole collapse is a major hazard causing substantial social and economic losses. However, the surface deformations and sinkhole evolution are rarely recorded, as these sites are known mainly after a collapse, making the assessment of sinkhole-related hazard challenging. Furthermore, more than 40% of the sinkholes of Italy are in seismically hazardous zones; it remains unclear whether seismicity may trigger sinkhole collapse. Here we use a multidisciplinary data set of InSAR, surface mapping and historical records of sinkhole activity to show that the Prà di Lama lake is a long-lived sinkhole that was formed in an active fault zone and grew through several events of unrest characterized by episodic subsidence and lake-level changes. Moreover, InSAR shows that continuous aseismic subsidence at rates of up to 7.1mmyr-1occurred during 2003-2008, between events of unrest. Earthquakes on the major faults near the sinkhole do not trigger sinkhole activity but low-magnitude earthquakes at 4-12 km depth occurred during sinkhole unrest in 1996 and 2016. We interpret our observations as evidence of seismic creep at depth causing fracturing and ultimately leading to the formation and growth of the Prà di Lama sinkhole

Localization of inhibin-activin subunits in normal pituitary and pituitary adenomas

The localization of inhibin/activin (I/A) subunits was investigated in human normal adenohypophysial cells and in 87 pituitary adenomas of different types, using immunohistochemistry. Monoclonal antibodies directed against alpha, beta A and beta B subunits of I/A were employed. In normal pituitary, alpha subunit of inhibin was detected only in FSH-positive gonadotrophs, while beta A subunit of I/A was expressed in FSH-positive gonadotrophs, GH-cells and in a few PRL-cells. beta B subunit was found in FSH-positive gonadotrophs, TSH-cells and a few LH-positive gonadotrophs. The three subunits of I/A were detected in the majority of nonfunctioning tumors, while functioning adenomas showed a significantly lower expression. This study shows that alpha, beta A and beta B subunits of I/A are expressed by specific adenohypophysial cell types and that they are characteristically present in nonfunctioning adenomas. These results suggest that inhibins and activins may play a role in the local regulation of pituitary hormonal secretion both in normal adenohypophysial cells and in pituitary adenoma

Novel Silicon n-in-p Pixel Sensors for the future ATLAS Upgrades

In view of the LHC upgrade phases towards HL-LHC the ATLAS experiment plans to upgrade the Inner Detector with an all silicon system. The n-in-p silicon technology is a promising candidate for the pixel upgrade thanks to its radiation hardness and cost effectiveness, that allow for enlarging the area instrumented with pixel detectors. We present the characterization and performance of novel n-in-p planar pixel sensors produced by CiS (Germany) connected by bump bonding to the ATLAS readout chip FE-I3. These results are obtained before and after irradiation up to a fluence of 10^16 1-MeV n_eq/cm^2, and prove the operability of this kind of sensors in the harsh radiation environment foreseen for the pixel system at HL-LHC. We also present an overview of the new pixel production, which is on-going at CiS for sensors compatible with the new ATLAS readout chip FE-I4.Comment: Preprint submitted to NIM-A Proceedings (Elba 2012

El aire: hábitat y medio de transmisión de microorganismos

La atmósfera no tiene una microbiota autóctona pero es un medio para la dispersión de muchos tipos de microorganismos (esporas, bacterias, virus y hongos), procedentes de otros ambientes. Algunos han creado adaptaciones especializadas que favorecen su supervivencia y permanencia. Los microorganismos dispersados por el aire tiene una gran importancia biológica y económica. Producen enfermedades en plantas, animales y humanos, causan alteración de alimentos y materiales orgánicos y contribuyen al deterioro y corrosión de monumentos y metales. La Microbiología del aire comienza en el siglo XIX, con Pasteur y Miquel que diseñaron métodos para estudiar los microorganismos en el aire y descubrir la causa de algunas enfermedades. Desde entonces numerosos investigadores han trabajado en este campo tanto en el aire exterior como en recintos cerrados. Las enfermedades transmitidas por el aire, producidas por bacterias, virus y hongos, son las respiratorias (neumonía, tosferina, tuberculosis, legionelosis, resfriado, gripe), sistémicas (meningitis, sarampión, varicela, micosis) y alérgicas

comparison between thermal energy and acoustic emission for the fatigue behavior of steels

Abstract The paper is focused on the study of fatigue materials, using an energy approach, with the support of two different non-destructive techniques. Indeed, the analysis of the energy behavior was conducted by the simultaneous application of Acoustic Emission (AE) and Thermography (TH). The purpose of the paper was to compare and integrate the results obtained by the two methodologies to assess the fatigue behavior of materials. The experimental tests were carried out on flat steel specimens of steels commonly used for metal carpentry either under static loading or under sequences of increasing cyclic loading. The results allow to define the fatigue limit either by the thermography or by the acoustic emission and they are encouraging to continue the comparison and the integration between the two energetic methodologies

Localization of inhibins and activins in normal endocrine cells and endocrine tumors of the gut and pancreas: an immunohistochemical and in situ hybridization study

Activins and inhibins, which belong to the TGF beta family, are composed of different combinations of alpha-, betaA-, and betaB-subunits, resulting in inhibin A (alphabetaA), inhibin B (alphabetaB), activin A (betaAbetaA), activin B (betaBbetaB), and activin AB (betaAbetaB). They regulate several cell functions, acting as paracrine/autocrine factors. Their actions, which depend on binding to specific receptors, are also modulated by follistatin. Gastroenteropancreatic (GEP) endocrine cells and endocrine tumors (ETs) produce several growth factors, but it is not well known whether they express follistatin and the various inhibin/activin subunits. We studied their expression in 65 GEP ETs using immunohistochemistry (IHC) and in situ hybridization (ISH). The alpha-subunit and follistatin were not identified in normal GEP endocrine cells and were poorly expressed in ETs. A betaA-subunit immunoreactivity (IR) was detected in A-, G-, EC-, and GIP-cells, while betaB-chain IR was present only in D-cells. The mRNAs encoding for these molecules were poorly expressed in normal tissues. BetaA- and betaB-subunits were identified in several ETs by both IHC and ISH: betaA-subunit mainly in G-cell and A-cell ETs, and betaB-subunit in D-cell, A-cell, and EC-cell ETs. Our results demonstrate a differential expression of activin/inhibin subunits among different types of GEP endocrine cells and related tumors, suggesting a role in modulation of biological functions of these normal and neoplastic endocrine cell