Parametric Representation of Rank d Tensorial Group Field Theory: Abelian Models with Kinetic Term ∑s∣ps∣+μ\sum_{s}|p_s| + \mu

We consider the parametric representation of the amplitudes of Abelian models in the so-called framework of rank $d$ Tensorial Group Field Theory. These models are called Abelian because their fields live on $U(1)^D$. We concentrate on the case when these models are endowed with particular kinetic terms involving a linear power in momenta. New dimensional regularization and renormalization schemes are introduced for particular models in this class: a rank 3 tensor model, an infinite tower of matrix models $\phi^{2n}$ over $U(1)$, and a matrix model over $U(1)^2$. For all divergent amplitudes, we identify a domain of meromorphicity in a strip determined by the real part of the group dimension $D$. From this point, the ordinary subtraction program is applied and leads to convergent and analytic renormalized integrals. Furthermore, we identify and study in depth the Symanzik polynomials provided by the parametric amplitudes of generic rank $d$ Abelian models. We find that these polynomials do not satisfy the ordinary Tutte's rules (contraction/deletion). By scrutinizing the "face"-structure of these polynomials, we find a generalized polynomial which turns out to be stable only under contraction.Comment: 69 pages, 35 figure

Flagellate Dermatitis due to Bleomycin Intake

Flagellate dermatitis is a rare cutaneous manifestation in which long, striated erythematous lesion appear on the patient’s skin. It is most frequently associated with bleomycin treatment or Shiitake mushroom intake, but it may also be attributed to many other possible causes. Herein we present a case of striated, hyperpigmented lesions which occurred after bleomycin intake. The typical flagellate lesions appeared for the first time on the patient’s back and shoulders after the first course of chemotherapy for seminoma (bleomycin, etoposide, and cisplatin). The active lesions disappeared with the discontinuation of chemotherapy. Clinicians should be aware of flagellate pattern of dermatitis which may accompany different clinical situation

Flagellate Dermatitis due to Bleomycin Intake

Flagellate dermatitis is a rare cutaneous manifestation in which long, striated erythematous lesion appear on the patient’s skin. It is most frequently associated with bleomycin treatment or Shiitake mushroom intake, but it may also be attributed to many other possible causes. Herein we present a case of striated, hyperpigmented lesions which occurred after bleomycin intake. The typical flagellate lesions appeared for the first time on the patient’s back and shoulders after the first course of chemotherapy for seminoma (bleomycin, etoposide, and cisplatin). The active lesions disappeared with the discontinuation of chemotherapy. Clinicians should be aware of flagellate pattern of dermatitis which may accompany different clinical situation

Nevus Sebaceous with Multiple Basal Cell Carcinomas and Extracutaneous Abnormalities: Genetic Origin or Coincidence?

The association of cutaneous and extracutaneous abnormalities is a common phenomenon, widely described in a variety of genetic syn- dromes. Nevertheless, yet undescribed syndromic combinations may still exist. Herein we present a case report of a patient who was admitted to the Dermatology Department due to multiple basal cell carcinomas arising from nevus sebaceous. In addition to the cutaneous malignancies, the patient presented with palmoplantar keratoderma, prurigo nodularis, hypothyroid- ism, multiple lumbar abnormalities, uterine myoma, an ovarian cyst, and highly dysplastic colon adenoma. Such a combination of multiple disorders may indicate a genetic origin of the diseases

Nevus Sebaceous with Multiple Basal Cell Carcinomas and Extracutaneous Abnormalities: Genetic Origin or Coincidence?

The association of cutaneous and extracutaneous abnormalities is a common phenomenon, widely described in a variety of genetic syn- dromes. Nevertheless, yet undescribed syndromic combinations may still exist. Herein we present a case report of a patient who was admitted to the Dermatology Department due to multiple basal cell carcinomas arising from nevus sebaceous. In addition to the cutaneous malignancies, the patient presented with palmoplantar keratoderma, prurigo nodularis, hypothyroid- ism, multiple lumbar abnormalities, uterine myoma, an ovarian cyst, and highly dysplastic colon adenoma. Such a combination of multiple disorders may indicate a genetic origin of the diseases

Load Magnitude and Locomotion Strategy Alters Knee Mechanics in Recruit-Aged Women

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An algebraic Birkhoff decomposition for the continuous renormalization group

This paper aims at presenting the first steps towards a formulation of the Exact Renormalization Group Equation in the Hopf algebra setting of Connes and Kreimer. It mostly deals with some algebraic preliminaries allowing to formulate perturbative renormalization within the theory of differential equations. The relation between renormalization, formulated as a change of boundary condition for a differential equation, and an algebraic Birkhoff decomposition for rooted trees is explicited

ChIP-seq Analysis in R (CSAR): An R package for the statistical detection of protein-bound genomic regions

<p>Abstract</p> <p>Background</p> <p><it>In vivo </it>detection of protein-bound genomic regions can be achieved by combining chromatin-immunoprecipitation with next-generation sequencing technology (ChIP-seq). The large amount of sequence data produced by this method needs to be analyzed in a statistically proper and computationally efficient manner. The generation of high copy numbers of DNA fragments as an artifact of the PCR step in ChIP-seq is an important source of bias of this methodology.</p> <p>Results</p> <p>We present here an R package for the statistical analysis of ChIP-seq experiments. Taking the average size of DNA fragments subjected to sequencing into account, the software calculates single-nucleotide read-enrichment values. After normalization, sample and control are compared using a test based on the ratio test or the Poisson distribution. Test statistic thresholds to control the false discovery rate are obtained through random permutations. Computational efficiency is achieved by implementing the most time-consuming functions in C++ and integrating these in the R package. An analysis of simulated and experimental ChIP-seq data is presented to demonstrate the robustness of our method against PCR-artefacts and its adequate control of the error rate.</p> <p>Conclusions</p> <p>The software <it>ChIP-seq Analysis in R </it>(CSAR) enables fast and accurate detection of protein-bound genomic regions through the analysis of ChIP-seq experiments. Compared to existing methods, we found that our package shows greater robustness against PCR-artefacts and better control of the error rate.</p

Self-Reported Hidradenitis Suppurativa Severity: Is It Useful for Clinical Practice?

Introduction. Hidradenitis suppurativa (HS) is considered to be the most burdensome dermatosis, with a well-documented negative influence on quality of life (QoL). The patient’s perception of the disorder, assessed as the self-reported severity, has been used in other dermatoses but not in HS. The aim of this study was to evaluate the usefulness of self-reported HS severity in clinical practice. Methods. The study was performed on a group of 130 Spanish HS patients. HS severity was assessed for all the subjects. Hurley staging and patient self-reported severity were used. Moreover, QoL impairment was evaluated using the Dermatology Life Quality Index (DLQI) and the Hidradenitis Suppurativa Quality of Life 24 (HSQoL-24) questionnaire. Results. The severity of HS according to the Hurley staging was most commonly assessed as Hurley II (47.7%), indicating moderate disease, followed by severe disease (Hurley III, 26.9%) and mild disease (Hurley I, 25.4%). According to the patient self-reported HS severity, most of the patients reported having mild disease (76 patients, 58.5%), followed by moderate disease (31 patients, 23.8%). Only 23 patients (17.7%) assessed their disease as severe. Moreover, men reported mild disease significantly more frequently than women (70.9% and 49.3%, respectively; p = 0.014). The self-reported HS severity correlated positively with the effect of the disease on patient QoL assessed with DLQI (r = 0.288, p < 0.001). Likewise, a strong positive correlation was found between self-reported HS severity and QoL impairment assessed with HSQoL-24 (r = 0.404, p = 0.001). No statistically significant correlation between Hurley severity stage and DLQI or HSQoL-24 was found. Moreover, there were significant differences in both DLQI and HSQoL-24 total score between different self-reported HS severities. This was not seen for any of the QoL instruments or for Hurley severity staging. Conclusion. The results show that self-assessment severity may reflect patients’ subjective feelings more adequately than popular objective instruments, and there should be a place for its use in daily clinical practice