1,105 research outputs found

    The Metabolic Syndrome: A Modern Plague Spread by Modern Technology

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    Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/73419/1/j.1751-7176.2009.00191.x.pd

    Expression of human adenosine deaminase in nonhuman primates after retrovirus-mediated gene transfer.

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    Primate bone marrow cells were infected with a retroviral vector carrying the genes for human adenosine deaminase (h-ADA) and bacterial neomycin resistance (neor). The infected cells were infused back into the lethally irradiated donor animals. Several monkeys fully reconstituted and were shown to express the h-ADA and neor genes at low levels in their recirculating hematopoietic cells for short periods of time

    When research setting is important: the influence of subordinate self-esteem on reactions to abusive supervision

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    In this paper, we argue that the conflicting theoretical views regarding the role that self-esteem plays in the decision to become aggressive can be explained by the particular research methodology used. Specifically, we examine how individuals respond to a perceived abusive supervisor in two settings: (1) using scenarios and (2) in a field study. Results indicate that individuals with high selfesteem are more likely to become aggressive in response to an abusive supervisor in settings where they are asked what they would do (using scenarios). However, in field research settings, where they are asked what they did do, individuals with low self-esteem were more likely to become aggressive in response to an abusive supervisor

    Effects of Management Support, Team Member Support, and Job Status on Safety Climate and Employee Attitudes

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    This study examined the impact of management and team member support on employee attitudes through the mediating effect of safety climate. Five hundred fifty-six physicians and nurses from a large teaching hospital in the eastern United States completed survey items assessing their perceptions of management support, team member support, and safety climate as well as job satisfaction and organizational commitment. Results indicated that while job satisfaction and commitment were directly affected by perceptions of management and team member support, these relationships were also partially mediated by safety climate. In addition, the results suggested that team member support contributed to the prediction of safety climate over and above the effect of management support alone indicating that multiple sources of support may be important in developing positive safety climates. The hypothesized moderating effect of job status was not significant. Implications of the results and suggestions for future research are discussed

    Big-Bang Nucleosynthesis and the Baryon Density of the Universe

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    Big-bang nucleosynthesis is one of the cornerstones of the standard cosmology. For almost thirty years its predictions have been used to test the big-bang model to within a fraction of a second of the bang. The concordance that exists between the predicted and observed abundances of D, 3^3He, 4^4He and 7^7Li provides important confirmation of the standard cosmology and leads to the most accurate determination of the baryon density, between 1.7 \times 10^{-31}\gcmm3 and 4.1\times 10^{-31}\gcmm3 (corresponding to between about 1\% and 14\% of critical density). This measurement of the density of ordinary matter is crucial to almost every aspect of cosmology and is pivotal to the establishment of two dark-matter problems: (i) most of the baryons are dark, and (ii) if the total mass density is greater than about 14\% of the critical density as many determinations now indicate, the bulk of the dark matter must be ``nonbaryonic,'' comprised of elementary particles left from the earliest moments. We critically review the present status of primordial nucleosynthesis and discuss future prospects.Comment: 21 pages+6 figs, LaTeX(2.09), FERMILAB-Pub-94/174-A, Figures available by anonymous ftp in oddjob.uchicago.edu:/pub/bbnrev/fig?.ps (?=1,2,3,4,5,6) or email from [email protected] REVISIONS include new discussion and a new figur
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