1,207 research outputs found
Adiabatic invariance with first integrals of motion
The construction of a microthermodynamic formalism for isolated systems based
on the concept of adiabatic invariance is an old but seldom appreciated effort
in the literature, dating back at least to P. Hertz [Ann. Phys. (Leipzig) 33,
225 (1910)]. An apparently independent extension of such formalism for systems
bearing additional first integrals of motion was recently proposed by Hans H.
Rugh [Phys. Rev. E 64, 055101 (2001)], establishing the concept of adiabatic
invariance even in such singular cases. After some remarks in connection with
the formalism pioneered by Hertz, it will be suggested that such an extension
can incidentally explain the success of a dynamical method for computing the
entropy of classical interacting fluids, at least in some potential
applications where the presence of additional first integrals cannot be
ignored.Comment: 2 pages, no figures (REVTeX 4
Nuts about Inquiry: Peanut Variation and Natural Selection
Despite the numerous advantages of using inquiry, many teachers do not use this method because of issues such as time constraints and increased workload. In addition, content such as evolution is particularly problematic to teach because of the perceived lack of hands-on activities and societal pressures. This inquiry activity is designed to help students understand an important component of evolution by natural selection. Through this activity students better understand natural variation within populations using peanuts. Students are encouraged to make links between population data, population diversity and evolution by using collected data to construct and interpret graphs. This article promotes National Science Education Content Standards A, C, and G, Iowa Teaching Standards 1, 2, 3, 4, and 5
Resistance of Mice to Infection with Friend Disease Virus After Subcutaneous Injection of Friend Virus and Friend Spleen-Cells
Swiss mice injected subcutaneously with suspensions of spleen cells or an extract of spleens from mice infected with Friend virus develop resistance to subsequent intravenous inoculation of Friend virus. A single injection of either Friend virus or Friend cells induces resistance. Immunized mice display resistance when challenged 6 months after immunization and survive for at least 20 weeks after infection. Neutralization tests indicate that serum, but not lymphoid cells of resistant animals, can neutralize Friend virus. In vitro neutralization tests indicate that residence of virus within the peritoneal cavity of immune mice for 1 h sharply reduces the infective titer of the virus
Synthesis of titanate nanostructures using amorphous precursor material and their adsorption/photocatalytic properties
This paper reports on a new and swift hydrothermal chemical route to prepare
titanate nanostructures (TNS) avoiding the use of crystalline TiO2 as starting
material. The synthesis approach uses a commercial solution of TiCl3 as
titanium source to prepare an amorphous precursor, circumventing the use of
hazardous chemical compounds. The influence of the reaction temperature and
dwell autoclave time on the structure and morphology of the synthesised
materials was studied. Homogeneous titanate nanotubes with a high
length/diameter aspect ratio were synthesised at 160^{\circ}C and 24 h. A band
gap of 3.06\pm0.03 eV was determined for the TNS samples prepared in these
experimental conditions. This value is red shifted by 0.14 eV compared to the
band gap value usually reported for the TiO2 anatase. Moreover, such samples
show better adsorption capacity and photocatalytic performance on the dye
rhodamine 6G (R6G) photodegradation process than TiO2 nanoparticles. A 98%
reduction of the R6G concentration was achieved after 45 minutes of irradiation
of a 10 ppm dye aqueous solution and 1 g/L of TNS catalyst.Comment: 29 pages, 10 figures, accepted for publication in Journal of
Materials Scienc
Novel Methodology for Creating Macaque Retinas with Sortable Photoreceptors and Ganglion Cells
Purpose: The ability to generate macaque retinas with sortable cell populations would be of great benefit to both basic and translational studies of the primate retina. The purpose of our study was therefore to develop methods to achieve this goal by selectively labeling, in life, photoreceptors (PRs) and retinal ganglion cells (RGCs) with separate fluorescent markers. Methods: Labeling of macaque (Macaca fascicularis) PRs and RGCs was accomplished by subretinal delivery of AAV5-hGRK1-GFP, and retrograde transport of micro-rubyā¢ from the lateral geniculate nucleus, respectively. Retinas were anatomically separated into different regions. Dissociation conditions were optimized, and cells from each region underwent fluorescent activated cell sorting (FACS). Expression of retinal cell type- specific genes was assessed by quantitative real-time PCR to characterize isolated cell populations. Results: We show that macaque PRs and RGCs can be simultaneously labeled in-life and enriched populations isolated by FACS. Recovery from different retinal regions indicated efficient isolation/enrichment for PRs and RGCs, with the macula being particularly amendable to this technique. Conclusions: The methods and materials presented here allow for the identification of novel reagents designed to target retinal ganglion cells and/or photoreceptors in a species that is phylogenetically and anatomically similar to human. These techniques will enable screening of intravitreally- delivered AAV capsid libraries for variants with increased tropism for PRs and/or RGCs and the evaluation of vector tropism and/or cellular promoter activity of gene therapy vectors in a clinically relevant species
Stability and Electronic Properties of TiO2 Nanostructures With and Without B and N Doping
We address one of the main challenges to TiO2-photocatalysis, namely band gap
narrowing, by combining nanostructural changes with doping. With this aim we
compare TiO2's electronic properties for small 0D clusters, 1D nanorods and
nanotubes, 2D layers, and 3D surface and bulk phases using different
approximations within density functional theory and GW calculations. In
particular, we propose very small (R < 0.5 nm) but surprisingly stable
nanotubes with promising properties. The nanotubes are initially formed from
TiO2 layers with the PtO2 structure, with the smallest (2,2) nanotube relaxing
to a rutile nanorod structure. We find that quantum confinement effects - as
expected - generally lead to a widening of the energy gap. However,
substitutional doping with boron or nitrogen is found to give rise to
(meta-)stable structures and the introduction of dopant and mid-gap states
which effectively reduce the band gap. Boron is seen to always give rise to
n-type doping while depending on the local bonding geometry, nitrogen may give
rise to n-type or p-type doping. For under coordinated TiO2 surface structures
found in clusters, nanorods, nanotubes, layers and surfaces nitrogen gives rise
to acceptor states while for larger clusters and bulk structures donor states
are introduced
Recommended from our members
SMART-1 Impact Ground-based campaign
Based on predictions of impact magnitude and cloud ejecta dynamics, we organized a SMART-1 ground-based observation campaign to perform coordinated measurements of the impact. Results from the coordinated multi-site campaign will be discussed
GAD65 Autoantibody Responses in Japanese Latent Autoimmune Diabetes in Adult Patients
OBJECTIVEāTo determine whether development of insulin requirement in patients with latent autoimmune diabetes in adults (LADA) is accompanied with the emergence of a type 1 diabetesālike autoimmune response
Relating the thermodynamic arrow of time to the causal arrow
Consider a Hamiltonian system that consists of a slow subsystem S and a fast
subsystem F. The autonomous dynamics of S is driven by an effective
Hamiltonian, but its thermodynamics is unexpected. We show that a well-defined
thermodynamic arrow of time (second law) emerges for S whenever there is a
well-defined causal arrow from S to F and the back-action is negligible. This
is because the back-action of F on S is described by a non-globally Hamiltonian
Born-Oppenheimer term that violates the Liouville theorem, and makes the second
law inapplicable to S. If S and F are mixing, under the causal arrow condition
they are described by microcanonic distributions P(S) and P(S|F). Their
structure supports a causal inference principle proposed recently in machine
learning.Comment: 10 page
- ā¦