132 research outputs found

    Substrate-Integrated Folded Waveguide Slot Antenna

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    In recent years a number of researchers have proposed novel techniques for fabricating rectangular waveguide using microwave integrated circuit techniques. These so-called substrate integrated guides have been fabricated using multilayer LTCC, multi- and single-layer microwave laminates and photoimageable thick films. All of these structures result in dielectric filled rectangular waveguide and as such have a width reduction of 1/square root of the relative permittivity over conventional waveguide. Furthermore, by their very nature they are easily integrated with planar transmission lines and circuits, allowing hybrid waveguide/microstrip systems to be fabricated on a single substrate. Several researchers have investigated slot antennas and arrays in substrate-integrated guide. In this paper we show a slot antenna in a folded substrate-integrated waveguide. These waveguides have half the width of the other types of substrate-integrated waveguide. As such the present structure allows arrays of slot antennas to be more highly integrated

    Computational Modeling of the Experimental Response of Microscale Bistable Tensegrity Structures

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    We report about the analysis, design, and experimental testing of modular structures composed of bistable units derived from the classic triangular tensegrity prism. Tensegrity structures are pinconnected frameworks, composed by bars and cables, possessing internal mechanisms and self-stress states, and featuring a variety of structural responses depending on their prestress, edge connectivity, and geometry. When a tensegrity system has only one internal mechanism and one self-stress state, as in the triangular prism case, it is possible to associate to it a corresponding bistable unit, by replacing all cables with bars and changing their edge-lengths slightly. After presenting experimental results of compression tests carried out on microscale specimens fabricated through multiphoton lithography, we compare them with the numerical predictions obtained by our computational model

    IMECE2002-33859 MANUFACTURING OF ELECTRICALLY CONDUCTIVE MICROSTRUCTURES BY DROPWISE PRINTING AND LASER CURING OF NANOPARTICLE-SUSPENSIONS

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    ABSTRACT A novel method for the manufacturing of electric microconductors for semiconductor and other devices is presented. The method brings together three technologies: controlled (on demand) printing, laser curing, and the employment of nanoparticles of matter, possessing markedly different properties (here, melting point) than their bulk counterparts. A suspension of gold particles in toluene solvent is employed to print electrically conducting line patterns utilizing a modified on demand ink jet printing process. To this end, microdroplets of 80-100 ”m diameters are deposited on a moving substrate such that the droplets form continuous lines. Focused laser irradiation is utilized in order to evaporate the solvent, melt the metal nanoparticles in the suspension, and sinter the suspended particles to form continuous, electrically conducting gold microlines on a substrate. The ultra fine particles in the suspension have a diameter size range of 2 -5 nm. Due to curvature effects of such small particles, the melting point is markedly lower (400°C) than that of bulk gold (1063°C). Thermodynamic aspects of the effect of particle size on the melting and evaporation temperatures of gold and toluene, respectively, are discussed in the paper. The structure and line width of the cured line as a function of the laser irradiation power and stage velocity are reported in detail. Preliminary measurements of the electrical conductivity are represented

    On the fabrication and mechanical modelling microscale bistable tensegrity systems

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    Abstract We report about the analysis, design, and experimental testing of modular structures composed of bistable units derived from the classic triangular tensegrity prism. Tensegrity structures are pin-connected frameworks, composed by bars and cables, possessing internal mechanisms and self-stress states, and featuring a variety of structural responses depending on their prestress, edge connectivity, and geometry. When a tensegrity system has only one internal mechanism and one self-stress state, as in the triangular prism case, it is possible to associate to it a corresponding bistable unit, by replacing all cables with bars and changing their edge-lengths slightly. After presenting experimental results of compression tests carried out on microscale specimens fabricated through multiphoton lithography, we compare them with the numerical predictions obtained by our computational model

    Advanced Hodgkin lymphoma in the East of England: a 10-year comparative analysis of outcomes for real-world patients treated with ABVD or escalated-BEACOPP, aged less than 60 years, compared with 5-year extended follow-up from the RATHL trial

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    Treatment with ABVD (doxorubicin, bleomycin, vinblastine, and dacarbazine) or escalated(e)-BEACOPP (bleomycin, etoposide, doxorubicin, cyclophosphamide, vincristine, procarbazine, and prednisolone) remains the international standard of care for advanced-stage classical Hodgkin lymphoma (HL). We performed a retrospective, multicentre analysis of 221 non-trial (“real-world”) patients, aged 16–59 years, diagnosed with advanced-stage HL in the Anglia Cancer Network between 2004 and 2014, treated with ABVD or eBEACOPP, and compared outcomes with 1088 patients in the Response-Adjusted Therapy for Advanced Hodgkin Lymphoma (RATHL) trial, aged 18–59 years, with median follow-up of 87.0 and 69.5 months, respectively. Real-world ABVD patients (n=177) had highly similar 5-year progression-free survival (PFS) and overall survival (OS) compared with RATHL (PFS 79.2% vs 81.4%; OS 92.9% vs 95.2%), despite interim positron-emission tomography-computed tomography (PET/CT)-guided dose-escalation being predominantly restricted to trial patients. Real-world eBEACOPP patients (n=44) had superior PFS (95.5%) compared with real-world ABVD (HR 0.20, p=0.027) and RATHL (HR 0.21, p=0.015), and superior OS for higher-risk (international prognostic score ≄3 [IPS 3+]) patients compared with real-world IPS 3+ ABVD (100% vs 84.5%, p=0.045), but not IPS 3+ RATHL patients. Our data support a PFS, but not OS, advantage for patients with advanced-stage HL treated with eBEACOPP compared with ABVD and suggest higher-risk patients may benefit disproportionately from more intensive therapy. However, increased access to effective salvage therapies might minimise any OS benefit from reduced relapse rates after frontline therapy
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