7,428 research outputs found
Macro-panels and Reality
This note argues that large VAR models with common cyclical feature restrictions provide an attractive framework for parsimonious implied univariate final equations, justifying on the one hand the estimation of homogenous panels with dynamic heterogeneity and a common factor structure, and on the other hand the aggregation of time series. However, starting with a too restrictive DGP might preclude from looking at interesting empirical issues.Economics (Jel: A)
Study of meta-analysis strategies for network inference using information-theoretic approaches
© 2017 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works.Reverse engineering of gene regulatory networks (GRNs) from gene expression data is a classical challenge in systems biology. Thanks to high-throughput technologies, a massive amount of gene-expression data has been accumulated in the public repositories. Modelling GRNs from multiple experiments (also called integrative analysis) has; therefore, naturally become a standard procedure in modern computational biology. Indeed, such analysis is usually more robust than the traditional approaches focused on individual datasets, which typically suffer from some experimental bias and a small number of samples.
To date, there are mainly two strategies for the problem of interest: the first one (”data merging”) merges all datasets together and then infers a GRN whereas the other (”networks ensemble”) infers GRNs from every dataset separately and then aggregates them using some ensemble rules (such as ranksum or weightsum). Unfortunately, a thorough comparison of these two approaches is lacking.
In this paper, we evaluate the performances of various metaanalysis approaches mentioned above with a systematic set of experiments based on in silico benchmarks. Furthermore, we present a new meta-analysis approach for inferring GRNs from multiple studies. Our proposed approach, adapted to methods based on pairwise measures such as correlation or mutual information, consists of two steps: aggregating matrices of the pairwise measures from every dataset followed by extracting the network from the meta-matrix.Peer ReviewedPostprint (author's final draft
Fractal universe and quantum gravity
We propose a field theory which lives in fractal spacetime and is argued to
be Lorentz invariant, power-counting renormalizable, ultraviolet finite, and
causal. The system flows from an ultraviolet fixed point, where spacetime has
Hausdorff dimension 2, to an infrared limit coinciding with a standard
four-dimensional field theory. Classically, the fractal world where fields live
exchanges energy momentum with the bulk with integer topological dimension.
However, the total energy momentum is conserved. We consider the dynamics and
the propagator of a scalar field. Implications for quantum gravity, cosmology,
and the cosmological constant are discussed.Comment: 4 pages. v2: typos corrected; v3: discussion improved, intuitive
introduction added, matches the published versio
Growth-Induced Strain in Chemical Vapor Deposited Monolayer MoS2: Experimental and Theoretical Investigation
Monolayer molybdenum disulphide (MoS) is a promising two-dimensional (2D)
material for nanoelectronic and optoelectronic applications. The large-area
growth of MoS has been demonstrated using chemical vapor deposition (CVD)
in a wide range of deposition temperatures from 600 {\deg}C to 1000 {\deg}C.
However, a direct comparison of growth parameters and resulting material
properties has not been made so far. Here, we present a systematic experimental
and theoretical investigation of optical properties of monolayer MoS grown
at different temperatures. Micro-Raman and photoluminescence (PL) studies
reveal observable inhomogeneities in optical properties of the as-grown single
crystalline grains of MoS. Close examination of the Raman and PL features
clearly indicate that growth-induced strain is the main source of distinct
optical properties. We carry out density functional theory calculations to
describe the interaction of growing MoS layers with the growth substrate as
the origin of strain. Our work explains the variation of band gap energies of
CVD-grown monolayer MoS, extracted using PL spectroscopy, as a function of
deposition temperature. The methodology has general applicability to model and
predict the influence of growth conditions on strain in 2D materials.Comment: 37 pages, 6 figures, 10 figures in supporting informatio
A reinforcement-learning model of top-down attention based on a potential-action map.
No abstract availabl
Ultra Low Specific Contact Resistivity in Metal-Graphene Junctions via Atomic Orbital Engineering
A systematic investigation of graphene edge contacts is provided.
Intentionally patterning monolayer graphene at the contact region creates
well-defined edge contacts that lead to a 67% enhancement in current injection
from a gold contact. Specific contact resistivity is reduced from 1372
{\Omega}m for a device with surface contacts to 456 {\Omega}m when contacts are
patterned with holes. Electrostatic doping of the graphene further reduces
contact resistivity from 519 {\Omega}m to 45 {\Omega}m, a substantial decrease
of 91%. The experimental results are supported and understood via a multi-scale
numerical model, based on density-functional-theory calculations and transport
simulations. The data is analyzed with regards to the edge perimeter and
hole-to-graphene ratio, which provides insights into optimized contact
geometries. The current work thus indicates a reliable and reproducible
approach for fabricating low resistance contacts in graphene devices. We
provide a simple guideline for contact design that can be exploited to guide
graphene and 2D material contact engineering.Comment: 26 page
Effects of nautical traffic and noise on foraging patterns of Mediterranean damlsefish (Chromis chromis)
Chromis chromis is a key species in the Mediterranean marine coastal ecosystems where, in summer, recreational boating and its associated noise overlap. Anthropogenic noise could induce behavioural modifications in marine organisms, thereby affecting population dynamics. In the case of an important species for the ecosystem like C. chromis, this could rebound on the community structure. Here, we measured nautical traffic during the summer of 2007 in a Southern Mediterranean Marine Protected Area (MPA) and simultaneously the feeding behaviour of C. chromis was video-recorded, within both the no-take A-zone and the B-zone where recreational use is allowed. Feeding frequencies, escape reaction and school density were analysed. C. chromis specimens were also collected from 2007 to 2008 to evaluate their physiological state using the Body Condition Index as a proxy of feeding efficiency. The MPA was more exploited by nautical tourism during holidays than on weekdays, particularly in the middle of the day. Greater traffic volume corresponded with lower feeding frequencies. The escape reaction was longer in duration (>1 min) when boat passed nearby, while moored boats did not induce an escape response. We found no differences in density between schools in the A- and B-zones and worse body conditions among those individuals inhabiting the B-zone in one area only. Overall, our findings revealed a significant modification of the daily foraging habits of C. chromis due to boat noise, which was slightly buffered by no-take zones established within the MPA
Progress on the implementation of Energy Performance Certificates in EU
Energy performance certificates (EPCs) are a key policy tool to inform about and to foster improvements to the energy performance of the building stock. Since their introduction in 2002 by the Energy Performance of Buildings Directive (EPBD), EPCs have been implemented across Member States (MSs) in different ways, depending on the political and legal context, the available technical capacities, as well as the characteristics of the buildings stock and buildings market in general.
In 2021, in the context of ?Fit for 55? legislative package, the European Commission proposed the third revision of the EPBD. The proposal improves the provisions on EPCs, their issuing and display, and their databases. In particular, it pursues harmonisation across MSs through a mandatory template for EPCs and a harmonised scale of energy performance classes.
This report presents the results of a survey conducted by JRC among MSs to collect information on how each MS has implemented the EPC scheme. It highlights differences among MSs regarding the energy uses included in the calculation, the floor area considered, the definition of energy classes, the main indicator(s), the number of EPCs issued, the availability of a national register, the mechanisms in place to ensure the quality of EPCs
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