Effect of Delta Operator on Umbral Composition in Finite Operator calculus

The main objective of this paper is to propose the matrix representation of umbral composition and investigate the effect of delta operator on umbral composition by using the sequential representation of delta operator in finite operator calculus

Assessment of human leukocyte antigen immunogenicity: current methods, challenges and opportunities.

PURPOSE OF REVIEW: Donor-recipient human leukocyte antigen (HLA) matching improves outcomes after solid-organ transplantation, but current assessment of HLA incompatibility is inadequate as it does not consider the relative immunogenicity of individual HLA mismatches. In this article, we review existing strategies for assessing HLA immunogenicity and discuss current challenges and future opportunities in this field. RECENT FINDINGS: Current HLA immunogenicity algorithms focus primarily on the humoral component of the alloimmune response and aim to determine a measure of 'dissimilarity' between donor and recipient HLA. This can be achieved by deriving information from comparison of donor and recipient HLA at the amino acid sequence, structural and/or the physicochemical level, accounting for both B-cell and T-cell pathways of alloreactivity. Substantial evidence now supports the superiority of this molecular definition of HLA incompatibility, over conventional enumeration of HLA antigenic differences, for assessing the risk of humoral alloimmunity and for predicting graft outcomes after transplantation. SUMMARY: Significant progress has been made in developing computational HLA immunogenicity algorithms that offer exciting opportunities for a more rational approach to determining the degree of donor-recipient HLA incompatibility and to defining HLA-related immunological risk. A number of challenges now need to be overcome to enable their implementation into clinical practice

Effect of Stacking Fault Energy on Microstructure and Texture Evolution in Ni-Co Alloys during Severe Plastic Deformation by High Pressure Torsion

The effect of stacking fault energy on microstructure, micro texture and hardness evolution in Ni-Co alloys during severe plastic deformation by high pressure torsion was studied in the present work. For this purpose a series of Ni-Co alloys have been chosen as model alloy systems with composition of Ni-20%Co, Ni-40%Co and Ni-60%Co with decreasing stacking fault energies. These alloys were severe deformed by high pressure torsion (HPT) at room temperature to different number of rotations (N), namely, N=1/12, 1/4, 1/8, 1/2, 1, 3, 5 and 10 under an applied load of 5GPa

Investigation on Performance of Pulsating Heat Pipe

The main aim is analysis the performance of pulsating heat pipe with open loop system. This design has effective to enhance the performance of heat pipe. The heat pipe having various limitations like capillary limit, boiling limit, entrainment limit, sonic limit etc. In this work, we analyze the overall heat transfer coefficient, heat transfer efficiency of the heat piper for different heat input and angle of variations. The work has been made with DI Water as working fluids. The performance of pulsating heat pipe tends to be better with heat pipe fabricated with 10mm size with Heat input of 50 W at angle inclination 45⁰

Evaluation of Rock Characteristics for a Power Plant Site in India

Extensive geotechnical and geophysical investigations were carried out for a power plant site situated on the east coast of southern India. It is proposed to construct the foundation on rock at a depth of 18.0 m below the ground level. The geological and geotechnical characterization of the rock have been presented in this paper. Extensive boreholes were drilled up to 40.0 m to 60.0 m depth and a few boreholes up to 120.0 m depth from the ground level. Seismic crosshole tests were conducted at soil/rock strata upto 65.0 m depth for the determination of S-wave and P-wave velocity at different depths. Dilatometer tests were conducted in weathered and hard rock at 5.0 m interval up to a depth of 65.0 m. Field permeability tests were carried out in deep boreholes by single packer method. Various laboratory tests including UCC, Brazilian, and Point load tests were carried out on rock core samples. Modules obtained from UCC tests are compared with the in-situ modulus obtained from Dilatometer tests. Bearing capacity and settlement analysis are carried out for the proposed raft of about 113 m x 105 m size to be supported on rock. The allowing bearing pressure is estimated based on Rock Mass Rating, RQD and strength of rock cores. The settlement analysis is carried out using modulus obtained from Dilatometer tests and from the laboratory unconfined compression tests on rock core samples. The modulus of subgrade reaction and spring constants in vertical, horizontal and rocking modes of vibration are also evaluated for the static and seismic analysis of the raft

Review on Sparse-Based Multipath Estimation and Mitigation: Intense Solution to Counteract the Effects in Software GPS Receivers

Multipath is the major concern in GPS receivers that fade the actual GPS signal causes positioning error up to 10 m so special care need to be taken to mitigate the multipath effects. Numerous methods like hardware based antenna arrays technique, receiver based narrow correlator receiver, double -delta discriminator, Adaptive Multipath Estimator, Wavelet Transformation and Particle filter, Kalman filter based post receiver methods etc. used to resolve the problem. But some of the methods can only reduce code multipath error but not effective in eliminating carrier multipath error. Most of these techniques are based on the assumption that the Line-of-Sight (LOS) signal is stronger than the Non-Line of-Sight (NLOS) signals. However, in the scenarios where the LOS signal is weaker than the composite multipath signal, this approach may result in a bias in code tracking. In this chapter, different types of multipath mitigation and its limitation are described. The recent development in sparse signal processing based blind channel estimation is investigated to compensate the multipath error. The Rayleigh and Rician fading model with different multipath parameters are simulated to test the urban scenario. The inverse problem of finding the GPS signal is addressed based on the deconvolution approach. To solve linear inverse problems, the suitable kind of appropriate objective function has been formulated to find the signal of interest. By exploiting this methods, the signal is observed and the carrier and code tracking loop parameters are computed with minimal error

Temperature dependence of chemical and biophysical rate processes: Phenomenological approach to deviations from Arrhenius law

Arrhenius plots, which are used to represent the effects of temperature on the rates of chemical and biophysical processes and on various transport phenomena in materials science, may exhibit deviations from linearity. Account of curvature is provided here by a formula which involves a deformation of the exponential function, of the kind recently encountered in treatments of non-extensivity in statistical mechanics. We present here examples on diverse topics – respiration rates of plants, speed of gliding of bacteria, quantum mechanical tunneling in a chemical reaction – illustrating the variety of possible applications and the additional insight that can be gained