511 research outputs found
Ultrahigh Bandwidth Spin Noise Spectroscopy: Detection of Large g-Factor Fluctuations in Highly n-Doped GaAs
We advance all optical spin noise spectroscopy (SNS) in semiconductors to
detection bandwidths of several hundred gigahertz by employing an ingenious
scheme of pulse trains from ultrafast laser oscillators as an optical probe.
The ultrafast SNS technique avoids the need for optical pumping and enables
nearly perturbation free measurements of extremely short spin dephasing times.
We employ the technique to highly n-doped bulk GaAs where magnetic field
dependent measurements show unexpected large g-factor fluctuations.
Calculations suggest that such large g-factor fluctuations do not necessarily
result from extrinsic sample variations but are intrinsically present in every
doped semiconductor due to the stochastic nature of the dopant distribution.Comment: 5 pages, 3 figure
Assessing the Factorial Validity of the Attitudes and Belief Scale 2-Abbreviated Version: A Call for the Development a Gold Standard Method of Measuring Rational and Irrational Beliefs
Rational Emotive Behaviour Therapy (REBT) does not possess a measure of rational and irrational beliefs that meets internationally recognised standards for acceptable psychometric properties. Without such a measure the theory/practice of REBT cannot be rigorously evaluated, thus undermining its scientific veracity. The current study investigates the validity and reliability of a recently developed measure of rational and irrational beliefs: the Attitudes and Belief Scale 2-Abbreviated Version (ABS-2-AV). University students from three countries completed the ABS-2-AV (N = 397). An alternative models framework using confirmatory factor analysis indicated that a theoretically consistent eight-factor model of the ABS-2-AV provided the best fit of the data. A number of post-hoc modifications were required in order to achieve acceptable model fit results, and these modifications revealed important methodological limitations with the ABS-2-AV. Results indicated that the validity of the ABS-2-AV was undermined due to items measuring both the psychological process of interest (rational and irrational beliefs) and the context in which these beliefs processes are presented. This is a serious methodological limitation of the ABS-2 and all questionnaires derived from it, including the ABS-2-AV. This methodological limitation resulted in the ABS-2-AV possessing poor internal reliability. These limitations are discussed in relation to the broader REBT literature and the impact such problems have on research and practice. A call is made for REBT researchers to come together to develop a “gold standard” method of assessing rational and irrational beliefs that meets international standard for psychometric excellence
Legumes as a Strategy for Reducing Greenhouse Gas Emissions of Forage-Livestock Systems
Incorporation of legumes into forage systems has been a widely adopted strategy to increase pasture productivity and forage nutritive value, while reducing N inputs. Considering the population growth, and the diminishing land resources for food production, the need to increase the food supply will have to be balanced with the environmental impact of these systems, particularly their carbon footprint. Enteric methane production represents the largest source of greenhouse gas emissions from livestock. Certain forage legumes have evolved plant secondary compounds, such as tannins and other polyphenols, which have been associated with reductions in enteric methane emissions. Studies were conducted at Utah State University (USU), and at the University of Florida, North Florida Research and Education Center (UF-NFREC) to assess in vivo methane emissions in grazing cattle, using the SF6 tracer technique. At USU, cattle grazing pastures of Birdsfoot trefoil (Lotus corniculatus; BFT) emitted less methane per unit of dry matter consumed when compared with cattle fed a totally mixed ration (50% barley grain, 25% alfalfa hay, and 25% corn silage) in ad libitum amounts. However, emissions in cattle grazing BFT did not differ from those grazing the legume Cicer milkvetch (Astragalus cicer), or a traditional pasture-finishing system based on Meadow brome (Bromus riparius). At UF-NFREC, three livestock-forage systems were tested during three consecutive years to determine the effects of including the legume Rhizoma peanut (Arachis glabrata Benth.; BHR) in bahiagrass pastures (Paspalum notatum Flügge) fertilized (BH) or not (BHF) with N during the warm season. No differences were observed in methane emissions (g d-1), or in methane emission intensity. From the legumes grazed in these experiments, only BFT contains significant concentrations of tannins. Thus, the potential to mitigate livestock enteric methane emissions by grazing legumes appears to be directly related to the presence of tannins
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The Jericho Option: Al-Qa'ida and Attacks on Critical Infrastructure
There is no doubt that al-Qaida and its affiliates have displayed, and continue to display, an acute interest in attacking targets that are considered to be important components of the infrastructure of the United States. What has not thus far been carried out, however, is an in-depth examination of the basic nature, historical evolution, and present scope of the organization's objectives that might help government personnel develop sound policy recommendations and analytical indicators to assist in detecting and interdicting plots of this nature. This study was completed with the financial support of the Lawrence Livermore National Laboratory, through a project sponsored by the U.S. Department of Homeland Security, Science and Technology Directorate. It is specifically intended to increase counterterrorism analysts understanding of certain features of al-Qaida's strategy and operations in order to facilitate the anticipation and prevention of attacks directed against our most critical infrastructures. The procedure adopted herein has involved consulting a wide variety of source materials that bear on the topic, ranging from sacred religious texts and historical accounts to al-Qaida-linked materials and the firsthand testimony of captured members of the group. It has also intentionally combined multiple approaches, including exploring the more esoteric religion-historical referents that have served to influence al-Qaida's behavior, providing a strategic analysis of its objectives and targeting rationales, closely examining the statements and writings of al-Qaida leaders and spokesmen (in part on the basis of material translated from primary sources), offering a descriptive analysis of its past global attack patterns, and producing concise but nonetheless in-depth case studies of its previous ''infrastructural'' attacks on U.S. soil. The analyses contained herein tend to support the preliminary assessment made by some of the authors in an earlier report, namely, that transnational jihadist organizations are amongst the extremist groups that are most likely to carry out successful attacks against targets that U.S. officials would categorize as elements of this country's critical infrastructure. These networks clearly have the operational capabilities to conduct these types of attacks, even on a large scale, and they display a number of ideological proclivities that may incline them to attack such targets. Although this seems self-evident, this study has also yielded more detailed insights into the behavior and orientation of al-Qaida and its affiliated networks
Nutrient Return from Plant Litter and Cattle Excretion Grazing on N-Fertilized Grass or Grass-Legume Pastures in North Florida
Nutrient recycling via plant litter and livestock excreta is an important ecosystem service provided by grasslands. This study determined nutrient return via these pathways in three grazing systems. The experiment was conducted from May to October (2016 and 2017) and treatments were: 1) Nitrogen fertilized bahiagrass (Paspalum notatum Flügge) pastures (112 kg N ha-1) during the warm-season, overseeded with a mixture (56 kg ha-1 of each) of ‘FL 401’ cereal rye (Secale cereale, L.) and ‘RAM’ oat (Avena sativa, L.) during the cool-season (BGN); 2) Ecoturf Rhizoma peanut (Arachis glabrata Benth.)/bahiagrass pastures during the warm-season, overseeded with similar rye/oat mixture fertilized with 34 kg N ha-1 plus a mixture of clovers (Trifolium incarnatum L., T. pretense L., and T. nigrescens L.) during the cool-season (BGRP); 3) unfertilized bahiagrass pastures during the warm-season, overseeded with similar rye/oat grass/clover mixture + 34 kg N ha-1 during the cool-season (BG). Litter mass was evaluated every 5wk. Litter decomposition was evaluated with incubation periods of 0, 2, 4, 8, 16, 32, 64, 128, and 256 days. Urine and fecal samples were collected for N concentration analysis. There was a net return of 47 kg N ha-1 season-1 via litter in all three systems without differing among them. In addition, litter decomposition rates were not different in the three systems. Conversely, N returned via excreta (urine and feces) was greater (63, 27, and 51 kg N ha-1 season-1) than that returned via litter (58.6, 41.6, and 41.2 kg ha-1 season-1). When assessing the proportions of N returning to the system via litter or excreta, no differences were observed among treatments, and on average 65.1 % of the N returned via excreta vs. 34.9 % returning via litter. The introduction of legumes could reduce the inputs from N fertilizers in grazing systems and keep the productivity similar because of more efficient N cycling
Ongoing under-reporting of clinically relevant safety data in phase II studies of tyrosine kinase inhibitors
status: publishe
Cardiac Magnetic Resonance Imaging to Determine Single Ventricle Function in a Pediatric Population is Feasible in a Large Trial Setting: Experience from the Single Ventricle Reconstruction Trial Longitudinal Follow up
The Single Ventricle Reconstruction (SVR) Trial was a randomized prospective trial designed to determine survival advantage of the modified Blalock-Taussig-Thomas shunt (BTTS) vs the right ventricle to pulmonary artery conduit (RVPAS) for patients with hypoplastic left heart syndrome. The primary aim of the long-term follow-up (SVRIII) was to determine the impact of shunt type on RV function. In this work, we describe the use of CMR in a large cohort follow up from the SVR Trial as a focused study of single ventricle function. The SVRIII protocol included short axis steady-state free precession imaging to assess single ventricle systolic function and flow quantification. There were 313 eligible SVRIII participants and 237 enrolled, ages ranging from 10 to 12.5 years. 177/237 (75%) participants underwent CMR. The most common reasons for not undergoing CMR exam were requirement for anesthesia (n = 14) or ICD/pacemaker (n = 11). A total of 168/177 (94%) CMR studies were diagnostic for RVEF. Median exam time was 54 [IQR 40-74] minutes, cine function exam time 20 [IQR 14-27] minutes, and flow quantification time 18 [IQR 12-25] minutes. There were 69/177 (39%) studies noted to have intra-thoracic artifacts, most common being susceptibility artifact from intra-thoracic metal. Not all artifacts resulted in non-diagnostic exams. These data describe the use and limitations of CMR for the assessment of cardiac function in a prospective trial setting in a grade-school-aged pediatric population with congenital heart disease. Many of the limitations are expected to decrease with the continued advancement of CMR technology
Herbage Accumulation and Nutritive Value of Limpograss Breeding Lines Under Stockpiling Management.
Supplements or conserved forage are often used to overcome forage quantity deficits for beef cattle, but stockpiled forage can be more economical. Limpograss [Hemarthria altissima (Poir.) Stapf & C.E. Hubb.] is the best available species for stockpiling in Florida because it is productive in autumn and maintains greater digestibility than other grasses at advanced stages of maturity. New limpograss hybrid breeding lines have been developed, but they have not been tested under stockpiling. Three limpograss breeding lines (1, 4F, and 10) and the most-used cultivar, Floralta, received 50 or 100 kg N ha?1 at initiation of stockpiling and herbage accumulated for 8, 12, or 16 wk. Entry 4F had greater herbage accumulation (7.3 Mg ha?1) than Entries 10, 1, and Floralta (6.1, 6.0, and 5.4 Mg ha?1, respectively). Entry 4F also had greater in vitro digestible organic matter (IVDOM) concentration (530?594 g kg?1) than Entries 1 and Floralta, but 4F was not different from Entry 10 (519?531 g kg?1) after 12 and 16 wk of accumulation. As stockpiling period increased from 8 to 16 wk, herbage accumulation increased from 5.3 to 7.4 Mg ha?1, dead material proportion increased from 1 to 10%, and herbage crude protein (CP) decreased from 44 to 32 g kg?1. Limpograss hybrids 4F and 10 are superior to Floralta for stockpiling, stockpiling period should not be longer than 12 wk, and protein supplement will be required to achieve satisfactory animal performance on stockpiled limpograss
Missed Opportunities: Family History and Behavioral Risk Factors in Breast Cancer Risk Assessment Among a Multiethnic Group of Women
BACKGROUND: Clinician’s knowledge of a woman’s cancer family history (CFH) and counseling about health-related behaviors (HRB) is necessary for appropriate breast cancer care. OBJECTIVE: To evaluate whether clinicians solicit CFH and counsel women on HRB; to assess relationship of well visits and patient risk perception or worry with clinician’s behavior. DESIGN: Cross-sectional population-based telephone survey. PARTICIPANTS: Multiethnic sample; 1,700 women from San Francisco Mammography Registry with a screening mammogram in 2001–2002. MEASUREMENTS: Predictors: well visit in prior year, self-perception of 10-year breast cancer risk, worry scale. Outcomes: Patient report of clinician asking about CFH in prior year, or ever counseling about HRB in relation to breast cancer risk. Multivariate models included age, ethnicity, education, language of interview, insurance/mammography facility, well visit, ever having a breast biopsy/follow-up mammography, Gail-Model risk, Jewish heritage, and body mass index. RESULTS: 58% reported clinicians asked about CFH; 33% reported clinicians ever discussed HRB. In multivariate analysis, regardless of actual risk, perceived risk, or level of worry, having had a well visit in prior year was associated with increased odds (OR = 2.3; 95% CI 1.6, 3.3) that a clinician asked about CFH. Regardless of actual risk of breast cancer, a higher level of worry (OR = 1.9; 95% CI 1.4, 2.6) was associated with increased odds that a clinician ever discussed HRB. CONCLUSIONS: Clinicians are missing opportunities to elicit family cancer histories and counsel about health-related behaviors and breast cancer risk. Preventive health visits offer opportunities for clinicians to address family history, risk behaviors, and patients’ worries about breast cancer
Sustainable intensification of livestock production on pastures
Growing human population and limited natural resources require a sustainable intensification of agricultural production systems. The ‘green revolution’ was successful in increasing world food production, but unintended consequences, including pollution of groundwater, soil erosion, climate change, and intensive use of agrochemicals, left a large footprint in the environment. Sustainable livestock intensification (SLI) implies greater productivity and more efficient use of natural resources, reducing the impact of livestock systems in the environment. Approaches to reach this goal include diversification of plant species and plant functional groups, multiple ruminant species, improvement in feeding techniques and grazing management, plant breeding for improved nutrient use efficiency, integrated crop-livestock systems, and silvopasture systems. Greater use of forage legumes appears to be an opportunity for SLI in extensive C4 grass-based pastureland commonly found in vast areas of Latin America. Grasslands in the 21st century will also be valued for multiple services they provide to humankind, and mechanisms of payment for these services are needed. A more ‘holistic’ approach will improve the social and economic sustainability of livestock systems. Achieving long-term sustainability must match short-term profits. Diversification of the products and services provided by grassland ecosystems is key to reach SLI in the near future
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