3,129 research outputs found
Utilization of Dynamic and Static Sensors for Monitoring Infrastructures
Infrastructures, including bridges, tunnels, sewers, and telecommunications, may be exposed to environmental-induced or traffic-induced deformation and vibrations. Some infrastructures, such as bridges and roadside upright structures, may be sensitive to vibration and displacement where several different types of dynamic and static sensors may be used for their measurement of sensitivity to environmental-induced loads, like wind and earthquake, and traffic-induced loads, such as passing trucks. Remote sensing involves either in situ, on-site, or airborne sensing where in situ sensors, such as strain gauges, displacement transducers, velometers, and accelerometers, are considered conventional but more durable and reliable. With data collected by accelerometers, time histories may be obtained, transformed, and then analyzed to determine their modal frequencies and shapes, while with displacement and strain transducers, structural deflections and internal stress distribution may be measured, respectively. Field tests can be used to characterize the dynamic and static properties of the infrastructures and may be further used to show their changes due to damage. Additionally, representative field applications on bridge dynamic testing, seismology, and earthborn/construction vibration are explained. Sensor data can be analyzed to establish the trend and ensure optimal structural health. At the end, five case studies on bridges and industry facilities are demonstrated in this chapter
Crystallographic Interdigitation in Oyster Shell Folia Enhances Material Strength
Shells of oyster species belonging to the genus Crassostrea have similar shell microstructural features comprising well-ordered calcite folia. However, the mechanical strengths of folia differ dramatically between closely related species. For example, the calcareous shells of the Hong Kong oyster Crassostrea hongkongensis are stronger than those of its closest relative, the Portuguese oyster, Crassostrea angulata. Specifically, after removal of organic content, the folia of C. hongkongensis are 200% tougher and able to withstand a 100% higher crushing force than that of C. angulata. Detailed analyses of shell structural and mechanical features support the hypothesis that crystallographic interdigitations confer elevated mechanical strength in C. hongkongensis oyster shells compared to C. angulata shells. Consequently, the folia of C. hongkongensis are structurally equipped to withstand a higher external load compared to C. angulata. The observed relationships between oyster shell structure, crystallography, and mechanical properties provided an insightful context in which to consider the likely fate of these two species in future climate change scenarios. Furthermore, the interdisciplinary approach developed in this study through integrating electron backscatter diffraction (EBSD) data into finite element analysis (FEA) could be applied to other biomineral systems to investigate the relationship between crystallography and mechanical behavior
Pressure Dependence of Fragile-to-Strong Transition and a Possible Second Critical Point in Supercooled Confined Water
By confining water in nano-pores of silica glass, we can bypass the
crystallization and study the pressure effect on the dynamical behavior in
deeply supercooled state using neutron scattering. We observe a clear evidence
of a cusp-like fragile-to-strong (F-S) dynamic transition. Here we show that
the transition temperature decreases steadily with an increasing pressure,
until it intersects the homogenous nucleation temperature line of bulk water at
a pressure of 1600 bar. Above this pressure, it is no longer possible to
discern the characteristic feature of the F-S transition. Identification of
this end point with the possible second critical point is discussed.Comment: 4 pages, 3 figure
Absorption cross sections of HCl and DCl at 135-232 nanometers: implications for photodissociation on Venus
Cross sections for photoabsorption of HCl and DCl are determined in the spectral region of 135-232 nm using radiation from a synchrotron light source. At wavelengths near the onset of absorption (λ > 200 nm), cross sections of HCl are approximately 5-10 times larger than those of DCl. These data are used to calculate rates of photodissociation of HCl and DCl in the Venusian atmosphere. For the entire wavelength region measured, the rate of photodissociation of DCl is only 16% that of HCl. The difference in rates of photodissociation contributes to the exceptionally large [D]/[H] ratio of the Venusian atmosphere
Ganglionated plexi and ligament of Marshall ablation reduces atrial vulnerability and causes stellate ganglion remodeling in ambulatory dogs
Background
Simultaneous activation of the stellate ganglion (SGNA), the ligament of Marshall (LOM) and the ganglionated plexi (GP) often precedes the onset of paroxysmal atrial tachyarrhythmias (PAT).
Objective
To test the hypothesis that ablation of the LOM and the superior left GP (SLGP) reduces atrial vulnerability and results in remodeling of the stellate ganglion.
Methods
Nerve activity was correlated to PAT and ventricular rate (VR) at baseline, after ablation of the LOM and SLGP, and after AF. Neuronal cell death was assessed with Tyrosine hydroxylase (TH) and terminal deoxynucleotidyl transferase dUTP nick end label (TUNEL) staining.
Results
There were 4±2 PAT episodes per day in controls. None were observed in the ablation group; even though SGNA and VR increased from 2.2 μV (95% confidence interval (CI); 1.2 – 3.3 μV) and 80 bpm (CI 68 – 92 bpm) at baseline to 3.0 μV (CI 2.6 – 3.4 μV, p=0.046) and 90 bpm (CI 75 – 108 bpm, p=0.026) after ablation, and to 3.1 μV (CI 1.7 – 4.5 μV, p=0.116) and 95 bpm (CI 79 – 110 bpm, p=0.075) after AF. There was an increase in TH-negative cells in the ablation group and a 19.7% (CI, 8.6 – 30.8%) TUNEL-positive staining in both the left and right SG. None were observed in the control group.
Conclusion
LOM and SLGP ablation caused LSG remodeling and cell death. There was reduced correlation of the VR response and PAT to SGNA. These findings support the importance of SLGP and LOM in atrial arrhythmogenesis
Antiarrhythmic effects of stimulating the left dorsal branch of the thoracic nerve in a canine model of paroxysmal atrial tachyarrhythmias
Background
Stellate ganglion nerve activity (SGNA) precedes paroxysmal atrial tachyarrhythmia (PAT) episodes in dogs with intermittent high-rate left atrial (LA) pacing. The left dorsal branch of the thoracic nerve (LDTN) contains sympathetic nerves originating from the stellate ganglia.
Objective
The purpose of this study was to test the hypothesis that high-frequency electrical stimulation of the LDTN can cause stellate ganglia damage and suppress PAT.
Methods
We performed chronic LDTN stimulation in 6 dogs with and 2 dogs without intermittent rapid LA pacing while monitoring SGNA.
Results
LDTN stimulation reduced average SGNA from 4.36 μV (95% confidence interval [CI] 4.10–4.62 μV) at baseline to 3.22 μV (95% CI 3.04–3.40 μV) after 2 weeks (P = .028) and completely suppressed all PAT episodes in all dogs studied. Tyrosine hydroxylase staining showed large damaged regions in both stellate ganglia, with increased percentages of tyrosine hydroxylase–negative cells. The terminal deoxynucleotidyl transferase dUTP nick end labeling assay showed that 23.36% (95% CI 18.74%–27.98%) of ganglion cells in the left stellate ganglia and 11.15% (95% CI 9.34%–12.96%) ganglion cells in the right stellate ganglia were positive, indicating extensive cell death. A reduction of both SGNA and heart rate was also observed in dogs with LDTN stimulation but without high-rate LA pacing. Histological studies in the latter 2 dogs confirmed the presence of extensive stellate ganglia damage, along with a high percentage of terminal deoxynucleotidyl transferase dUTP nick end labeling–positive cells.
Conclusion
LDTN stimulation damages both left stellate ganglia and right stellate ganglia, reduces left SGNA, and is antiarrhythmic in this canine model of PAT
Quantitative test of the barrier nucleosome model for statistical positioning of nucleosomes up- and downstream of transcription start sites
The positions of nucleosomes in eukaryotic genomes determine which parts of
the DNA sequence are readily accessible for regulatory proteins and which are
not. Genome-wide maps of nucleosome positions have revealed a salient pattern
around transcription start sites, involving a nucleosome-free region (NFR)
flanked by a pronounced periodic pattern in the average nucleosome density.
While the periodic pattern clearly reflects well-positioned nucleosomes, the
positioning mechanism is less clear. A recent experimental study by Mavrich et
al. argued that the pattern observed in S. cerevisiae is qualitatively
consistent with a `barrier nucleosome model', in which the oscillatory pattern
is created by the statistical positioning mechanism of Kornberg and Stryer. On
the other hand, there is clear evidence for intrinsic sequence preferences of
nucleosomes, and it is unclear to what extent these sequence preferences affect
the observed pattern. To test the barrier nucleosome model, we quantitatively
analyze yeast nucleosome positioning data both up- and downstream from NFRs.
Our analysis is based on the Tonks model of statistical physics which
quantifies the interplay between the excluded-volume interaction of nucleosomes
and their positional entropy. We find that although the typical patterns on the
two sides of the NFR are different, they are both quantitatively described by
the same physical model, with the same parameters, but different boundary
conditions. The inferred boundary conditions suggest that the first nucleosome
downstream from the NFR (the +1 nucleosome) is typically directly positioned
while the first nucleosome upstream is statistically positioned via a
nucleosome-repelling DNA region. These boundary conditions, which can be
locally encoded into the genome sequence, significantly shape the statistical
distribution of nucleosomes over a range of up to ~1000 bp to each side.Comment: includes supporting materia
The Effect of Galaxy Interactions on Molecular Gas Properties
© 2018. The American Astronomical Society. All rights reserved.Galaxy interactions are often accompanied by an enhanced star formation rate (SFR). Since molecular gas is essential for star formation, it is vital to establish whether and by how much galaxy interactions affect the molecular gas properties. We investigate the effect of interactions on global molecular gas properties by studying a sample of 58 galaxies in pairs and 154 control galaxies. Molecular gas properties are determined from observations with the JCMT, PMO, and CSO telescopes and supplemented with data from the xCOLD GASS and JINGLE surveys at 12CO(1-0) and 12CO(2-1). The SFR, gas mass (), and gas fraction (f gas) are all enhanced in galaxies in pairs by ∼2.5 times compared to the controls matched in redshift, mass, and effective radius, while the enhancement of star formation efficiency (SFE ≡SFR/) is less than a factor of 2. We also find that the enhancements in SFR, and f gas, increase with decreasing pair separation and are larger in systems with smaller stellar mass ratio. Conversely, the SFE is only enhanced in close pairs (separation <20 kpc) and equal-mass systems; therefore, most galaxies in pairs lie in the same parameter space on the SFR- plane as controls. This is the first time that the dependence of molecular gas properties on merger configurations is probed statistically with a relatively large sample and a carefully selected control sample for individual galaxies. We conclude that galaxy interactions do modify the molecular gas properties, although the strength of the effect is dependent on merger configuration.Peer reviewedFinal Accepted Versio
Long-Range Transport of Asian Dust and Air Pollutants to Taiwan
Dust storms and long-range transport of pollutants are major environ-mental concerns of Taiwan during the winter monsoon season when north-easterly winds prevail following passages of cold fronts. To quantify the impact on air quality, we develop an objective method to classify and study the long-range transport processes by examining the frontal passages in two representative years. We have found that there is about one frontal passage per week in winter and spring, consistent with the climatological average. The long-range transport events are classified into three types ac-cording to their degrees of impact on levels of dusts and air pollutants in Taiwan, namely dust storms (DS), long-range transport with pollutants (FP), and long-range transport of background air masses (BG). DS cases occurred 4.7 % of the time over 14 months and had a large average PM10 concentra-tion of 127.6 µg m 3 − at Wan-Li station. FP cases occurred 1.9 % of the time and the mean concentration of PM10 during the FP periods was about 85 µg m 3 −. BG cases happened 18.6 % of the time and the mean concentra-tion of PM10 was 32.8 µg m 3−. Dust storms and air pollutants tend to be transported in different air parcels as evidenced by a lack of correlation between dust aerosols and air pollutants. The frequency of local pollution (LP) cases was 71.7 % in winter and spring. The average PM10 concentra-tion of LP cases at the Wan-Li station was 47.4 µg m 3 −. However, about one to two-thirds of the PM10 during LP cases can be attributed to the long
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