1,080 research outputs found
Lithium in the Symbiotic Mira V407 Cyg
We report an identification of the lithium resonance doublet LiI 6708A in the
spectrum of V407 Cyg, a symbiotic Mira with a pulsation period of about 745
days. The resolution of the spectra used was R~18500 and the measured
equivalent width of the line is ~0.34A. It is suggested that the lithium
enrichment is due to hot bottom burning in the intermediate mass AGB variable,
although other possible origins cannot be totally ruled out. In contrast to
lithium-rich AGB stars in the Magellanic clouds, ZrO 5551A, 6474A absorption
bands were not found in the spectrum of V407Cyg. These are the bands used to
classify the S-type stars at low-resolution. Although we identified weak ZrO
5718A, 6412A these are not visible in the low-resolution spectra, and we
therefore classify the Mira in V407 Cyg as an M type. This, together with other
published work, suggests lithium enrichment can precede the third dredge up of
s-process enriched material in galactic AGB stars.Comment: 4 pages, 2 figures, to be published in MNRA
Feline hypersomatotropism and acromegaly tumorigenesis: a potential role for the AIP gene
Acromegaly in humans is usually sporadic, however up to 20% of familial isolated pituitary adenomas are caused by germline sequence variants of the aryl-hydrocarbon-receptor interacting protein (AIP) gene. Feline acromegaly has similarities to human acromegalic families with AIP mutations. The aim of this study was to sequence the feline AIP gene, identify sequence variants and compare the AIP gene sequence between feline acromegalic and control cats, and in acromegalic siblings. The feline AIP gene was amplified through PCR using whole blood genomic DNA from 10 acromegalic and 10 control cats, and 3 sibling pairs affected by acromegaly. PCR products were sequenced and compared with the published predicted feline AIP gene. A single nonsynonymous SNP was identified in exon 1 (AIP:c.9T > G) of two acromegalic cats and none of the control cats, as well as both members of one sibling pair. The region of this SNP is considered essential for the interaction of the AIP protein with its receptor. This sequence variant has not previously been reported in humans. Two additional synonymous sequence variants were identified (AIP:c.481C > T and AIP:c.826C > T). This is the first molecular study to investigate a potential genetic cause of feline acromegaly and identified a nonsynonymous AIP single nucleotide polymorphism in 20% of the acromegalic cat population evaluated, as well as in one of the sibling pairs evaluated
The visibility of the Galactic bulge in optical surveys. Application to the Gaia mission
The bulge is a region of the Galaxy which is of tremendous interest for
understanding Galaxy formation. However, measuring photometry and kinematics in
it raises several inherent issues, like high extinction in the visible and
severe crowding. Here we attempt to estimate the problem of the visibility of
the bulge at optical wavelengths, where large CCD mosaics allow to easily cover
wide regions from the ground, and where future astrometric missions are
planned. Assuming the Besancon Galaxy model and high resolution extinction
maps, we estimate the stellar density as a function of longitude, latitude and
apparent magnitude and we deduce the possibility of reaching and measuring
bulge stars. The method is applied to three Gaia instruments, the BBP and MBP
photometers, and the RVS spectrograph. We conclude that, while in the BBP most
of the bulge will be accessible, in the MBP there will be a small but
significant number of regions where bulge stars will be detected and accurately
measured in crowded fields. Assuming that the RVS spectra may be extracted in
moderately crowded fields, the bulge will be accessible in most regions apart
from the strongly absorbed inner plane regions, because of high extinction, and
in low extinction windows like the Baades's window where the crowding is too
severe.Comment: 11 pages, 9 figures, accepted for publication in A&A, latex using A&A
macro
Fractal scan strategies for selective laser melting of âunweldableâ nickel superalloys
The high thermal gradients experienced during manufacture via selective laser melting commonly result in cracking of high Îł/ÎłâČ Nickel based superalloys. Such defects cannot be tolerated in applications where component integrity is of paramount importance. To overcome this, many industrial practitioners make use of hot isostatic pressing to âhealâ these defects. The possibility of such defects re-opening during the component life necessitates optimisation of SLM processing parameters in order to produce the highest bulk density and integrity in the as-built state.
In this paper, novel fractal scanning strategies based upon mathematical fill curves, namely the Hilbert and Peano-Gosper curve, are explored in which the use of short vector length scans, in the order of 100 ÎŒm, is used as a method of reducing residual stresses. The effect on cracking observed in CM247LC superalloy samples was analysed using image processing, comparing the novel fractal scan strategies to more conventional âislandâ scans. Scanning electron microscopy and energy dispersive X-ray spectroscopy was utilised to determine the cracking mechanisms.
Results show that cracking occurs via two mechanisms, solidification and liquation, with a strong dependence on the laser scan vectors. Through the use of fractal scan strategies, bulk density can be increased by 2 ± 0.7% when compared to the âislandâ scanning, demonstrating the potential of fractal scan strategies in the manufacture of typically âunweldableâ nickel superalloys
Syndromic surveillance to assess the potential public health impact of the Icelandic volcanic ash plume across the United Kingdom, April 2010
The Eyjafjallajökull volcano in Iceland erupted on 14 April 2010 emitting a volcanic ash plume that spread across the United Kingdom and mainland Europe. The Health Protection Agency and Health Protection Scotland used existing syndromic surveillance systems to monitor community health during the incident: there were no particularly unusual increases in any of the monitored conditions. This incident has again demonstrated the use of syndromic surveillance systems for monitoring community health in real time
Design Principles for Plasmonic Nanoparticle Devices
For all applications of plasmonics to technology it is required to tailor the
resonance to the optical system in question. This chapter gives an
understanding of the design considerations for nanoparticles needed to tune the
resonance. First the basic concepts of plasmonics are reviewed with a focus on
the physics of nanoparticles. An introduction to the finite element method is
given with emphasis on the suitability of the method to nanoplasmonic device
simulation. The effects of nanoparticle shape on the spectral position and
lineshape of the plasmonic resonance are discussed including retardation and
surface curvature effects. The most technologically important plasmonic
materials are assessed for device applicability and the importance of
substrates in light scattering is explained. Finally the application of
plasmonic nanoparticles to photovoltaic devices is discussed.Comment: 29 pages, 15 figures, part of an edited book: "Linear and Non-Linear
Nanoplasmonics
Meso-scale defect evaluation of selective laser melting using spatially resolved acoustic spectroscopy
Developments in additive manufacturing technology are serving to expand the potential applications. Critical developments are required in the supporting areas of measurement and in process inspection to achieve this. CM247LC is a nickel superalloy that is of interest for use in aerospace and civil power plants. However, it is difficult to process via selective laser melting (SLM) as it suffers from cracking during rapid cooling and solidification. This limits the viability of CM247LC parts created using SLM. To quantify part integrity, spatially resolved acoustic spectroscopy (SRAS) has been identified as a viable non-destructive evaluation technique. In this study, a combination of optical microscopy and SRAS was used to identify and classify the surface defects present in SLM-produced parts. By analysing the datasets and scan trajectories, it is possible to correlate morphological information with process parameters. Image processing was used to quantify porosity and cracking for bulk density measurement. Analysis of surface acoustic wave data showed that an error in manufacture in the form of an overscan occurred. Comparing areas affected by overscan with a bulk material, a change in defect density from 1.17% in the bulk material to 5.32% in the overscan regions was observed, highlighting the need to reduce overscan areas in manufacture
An investigation of polymorphisms in innate and adaptive immune response genes in canine leishmaniosis
The outcome of infection with Leishmania infantum in dogs is variable, which is thought to be due to the nature of the immune response mounted by the host. As a consequence, the clinical signs and severity of canine leishmaniosis vary between individual dogs. Host immunogenetic factors might play an important role in determining the outcome of infection. The aim of this study was to examine polymorphisms in innate and adaptive immune response genes, to determine whether any of these were associated with susceptibility or resistance to L. infantum infection. Genomic DNA was obtained from two groups: pet dogs in endemic regions of Europe and a group of Beagles exposed to sand fly infection as part of a vaccine study. Genotyping was performed using a SNP (single nucleotide polymorphism) array for selected immune response genes. The first part of the study compared 62 clinical cases with 101 clinically unaffected dogs that were seronegative for Leishmania antibodies. One SNP in the CIITA gene demonstrated a significantly higher minor allele frequency in the case group, compared with the control group at the individual SNP level after permutation, but was not significant after correction for multiple testing. The second part of the study examined 48 Beagle dogs exposed to L. infantum over two transmission seasons. Twenty-seven dogs with a resistant phenotype (no evidence of clinical disease, seronegative at the end of the study period, negative on lymph node culture and only transiently PCR positive in bone marrow) were compared with 21 dogs demonstrating a susceptible phenotype (clinical disease, seropositive, positive lymph node culture and consistently PCR positive in bone marrow). Three SNPs in TLR3, two SNPs in PTPN22 and one SNP in TLR4 and IL1A were associated with the susceptible phenotype in the Beagle group at the individual SNP level after permutation analysis, but were not significant after correction for multiple testing. Further validation of these SNPs is required in a larger cohort of dogs, ideally with extreme phenotypes to confirm an association with the outcome of L. infantum infection
The evolutionary state of Miras with changing pulsation periods
Context: Miras are long-period variables thought to be in the asymptotic
giant branch (AGB) phase of evolution. In about one percent of known Miras, the
pulsation period is changing. It has been speculated that this changing period
is the consequence of a recent thermal pulse in these stars. Aims: We aim to
clarify the evolutionary state of these stars, and to determine in particular
whether or not they are in the thermally-pulsing (TP-)AGB phase. Methods: One
important piece of information that has been neglected so far when determining
the evolutionary state is the presence of the radio-active s-process element
technetium (Tc). We obtained high-resolution, high signal-to-noise-ratio
optical spectra of a dozen prominent Mira variables with changing pulsation
period to search for this indicator of TPs and dredge-up. We also use the
spectra to measure lithium (Li) abundances. Furthermore, we establish the
evolutionary states of our sample stars by means of their present-day periods
and luminosities. Results: Among the twelve sample stars observed in this
programme, five were found to show absorption lines of Tc. BH Cru is found to
be a carbon-star, its period increase in the past decades possibly having
stopped by now. We report a possible switch in the pulsation mode of T UMi from
Mira-like to semi-regular variability in the past two years. R Nor, on the
other hand, is probably a fairly massive AGB star, which could be true for all
meandering Miras. Finally, we assign RU Vul to the metal-poor thick disk with
properties very similar to the short-period, metal-poor Miras. Conclusions: We
conclude that there is no clear correlation between period change class and Tc
presence. The stars that are most likely to have experienced a recent TP are BH
Cru and R Hya, although their rates of period change are quite different.Comment: 11 pages, 7 figures, 2 tables; accepted for publication in A&
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