APROVECHAMIENTO ALIMENTARIO DE INFLORESCENCIAS EN LA REGIÓN SIERRA DEL ESTADO DE TABASCO

This paper presents results from the research project named “Identification of theTraditional Alimentary Culture in the Stateof Tabasco”, SIGOLFO 97-06-007-T. Basedon questionnaires distributed in communities about 100 and 500 inhabitants, at leastone of them in each community being anindigenous speaker, it was found that theirinhabitants, for ancestral and cultural customs, are devoted to gathering plant species for supplying supplementary sustenance. The most important alternative vegetable source being gathered is inflorescences of species like Erythrinaamericana Mill., Calathea macrosepala(Aubl.) Lindl., Spathiphyllum phryniifolium Schott, Astrocaryum mexicanumLiebm., Chamaedora sp. aff. pinnatifronsLiebm. ex Mart. y Chamaedora cataractarum (Mart.). It was found that the consumption of inflorescences prevails in these communities as a nutrition base during periodsof food shortage or special celebrationssuch as Holy Week when Catholics do noteat meat.La presente información es parte de los resultados encontrados en el proyecto de investigación “Identificación de la CulturaAlimentaria Tradicional en el Estado deTabasco”, SIGOLFO 97-06-007-T. Con baseen la aplicación de cuestionarios en comunidades comprendidas entre 100 y 500 habitantes con al menos uno de ellos conhabla indígena, se encontró que por costumbres ancestrales y culturales se dedican a la recolección de especies vegetalespara suplementar su fuente de alimentación, con especies vegetales alternativas,siendo de gran importancia la recolecciónde inflorescencias de especies como:Erythrina americana Mill, Calatheamacrosepala (Aulb.) Lindl., Spathiphyllum phryniifolium Schoot,Astrocaryum mexicanum Liebmann,Chamaedora sp. aff. pinnatifrons Liebm.ex Mart y Chamaedora cataractarum(Mart). Se pudo constatar que prevaleceen las comunidades un gran arraigo delconsumo de especies con inflorescenciacomo una base de la alimentación durantelos periodos de escasez de alimentos o durante festividades como la Semana Santa,época en la cual de manera tradicional no se consume carne de ninguna especie yrara vez pescado o pollo

Small-molecule inhibitor of OGG1 suppresses pro-inflammatory gene expression and inflammation

The onset of inflammation is associated with reactive oxygen species and oxidative damage to macromolecules like 7,8-dihydro-8-oxoguanine (8-oxoG) in DNA. Because 8-oxoguanine DNA glycosylase 1 (OGG1) binds 8-oxoG and because Ogg1-deficient mice are resistant to acute and systemic inflammation, we hypothesized that OGG1 inhibition may represent a strategy for the prevention and treatment of inflammation. We developed TH5487, a selective active-site inhibitor of OGG1, which hampers OGG1 binding to and repair of 8-oxoG and which is well tolerated by mice. TH5487 prevents tumor necrosis factor–α–induced OGG1-DNA interactions at guanine-rich promoters of proinflammatory genes. This, in turn, decreases DNA occupancy of nuclear factor κB and proinflammatory gene expression, resulting in decreased immune cell recruitment to mouse lungs. Thus, we present a proof of concept that targeting oxidative DNA repair can alleviate inflammatory conditions in vivo

Chondrocyte differentiation for auricular cartilage reconstruction using a chitosan based hydrogel

Tissue engineering with the use of biodegradable and biocompatible scaffolds is an interesting option for ear repair. Chitosan-Polyvinyl alcohol-Epichlorohydrine hydrogel (CS-PVA-ECH) is biocompatible and displays appropriate mechanical properties to be used as a scaffold. The present work, studies the potential of CS-PVA-ECH scaffolds seeded with chondrocytes to develop elastic cartilage engineered-neotissues. Chondrocytes isolated from rabbit and swine elastic cartilage were independently cultured onto CS-PVA-ECH scaffolds for 20 days to form the appropriate constructs. Then, in vitro cell viability and morphology were evaluated by calcein AM and EthD-1 assays and Scanning Electron Microscopy (SEM) respectively, and the constructs were implanted in nu/nu mice for four months, in order to evaluate the neotissue formation. Histological analysis of the formed neotissues was performed by Safranin O, Toluidine blue (GAG’s), Verhoeff-Van Gieson (elastic fibers), Masson’s trichrome (collagen) and Von Kossa (Calcium salts) stains and SEM. Results indicate appropriate cell viability, seeded with rabbit or swine chondrocyte constructs; nevertheless, upon implantation the constructs developed neotissues with different characteristics depending on the animal species from which the seeded chondrocytes came from. Neotissues developed from swine chondrocytes were similar to auricular cartilage, while neotissues from rabbit chondrocytes were similar to hyaline cartilage and eventually they differentiate to bone. This result suggests that neotissue characteristics may be influenced by the animal species source of the chondrocytes isolated

Do the Naica giant crystals deteriorate due to human sction?

Resumen del trabajo presentado al 25th international Congress on X-ray optic and microanalysis (ICXOM), celebrado en EE.UU. del 5 al 9 de agosto de 2019.The support given by CONACYT Project No. 183706 and by SSRL, ELETTRA, ESRF synchrotron facilities is acknowledged. Authors are thankful to Cia. Peñoles and Naica Mine for providing samples