Treatment of Low-flow Vascular Malformations by Ultrasound-guided Sclerotherapy with Polidocanol Foam: 24 Cases and Literature Review

AbstractObjectivesTreatment by sclerotherapy has been suggested as a first-line treatment of low-flow vascular malformations. This study reports our experience in treating low-flow vascular malformations by ultrasound-guided sclerosis with polidocanol foam at the Vascular Medicine Department in Grenoble, France.DesignRetrospective single-centre consecutive series.Materials and methodsBetween January 2006 and December 2009, we analysed the complete records of patients with symptomatic low-flow vascular malformations of venous, lymphatic or complex type (Klippel–Trenaunay syndrome, KTS) treated by ultrasound-guided sclerosis. The therapeutic indication was always validated by the Consultative Committee for vascular malformations of the University Hospital of Grenoble. All vascular malformations were classified according to the Hamburg Classification. The sclerosing agent was polidocanol used as foam.ResultsA total of 24 patients between 7 and 78 years were treated (19 venous malformations, three KTSs and two venous-lymphatic malformations). The concentrations of polidocanol used ranged from 0.25% to 3%. The average number of sessions was 2.3 (1–16). After a median follow-up at 5 months after the last session, 23 out of 24 patients reported a decrease in pain; in nine cases (37.5%), over 50% reduction in size was observed, and in 14 cases (58.3%), a reduction of less than 50% of the original size was obtained. Two minor side effects were reported.ConclusionsTreatment by ultrasound-guided sclerosis using polidocanol foam seems to be well tolerated and can improve the symptoms of low-flow malformations without the risks of more aggressive sclerosing agents, such as ethanol

A Component Framework for Java-based Real-time Embedded Systems

Rank (CORE): A.International audienceThe Real-Time Specification for Java (RTSJ) is becoming a popular choice in the world of real-time and embedded programming. However, RTSJ introduces many non-intuitive rules and restrictions which prevent its wide adoption. Moreover, current state-of-the-art frameworks usually fail to alleviate the development process into higher layers of the software development life-cycle. In this paper we extend our philosophy that RTSJ concepts need to be considered at early stages of software development, postulated in our prior work, in a framework that provides continuum between the design and implementation process. A component model designed specially for RTSJ serves here as a cornerstone. As the first contribution of this work, we propose a development process where RTSJ concepts are manipulated independently from functional aspects. Second, we mitigate complexities of RTSJ-development by automatically generating execution infrastructure where real-time concerns are transparently managed. We thus allow developers to create systems for variously constrained real-time and embedded environments. Performed benchmarks show that the overhead of the framework is minimal in comparison to manually written object-oriented approach, while providing more extensive functionality. Finally, the framework is designed with the stress on dynamic adaptability of target systems, a property we envisage as a fundamental in an upcoming era of massively developed real-time systems

Toward the adaptation of component-based architectures by model transformation: behind smart user interfaces

Graphical user interfaces are not always developed for remaining static. There are GUIs with the need of implementing some variability mechanisms. Component-based GUIs are an ideal target for incorporating this kind of operations, because they can adapt their functionality at run-time when their structure is updated by adding or removing components or by modifying the relationships between them. Mashup user interfaces are a good example of this type of GUI, and they allow to combine services through the assembly of graphical components. We intend to adapt component based user interfaces for obtaining smart user interfaces. With this goal, our proposal attempts to adapt abstract component-based architectures by using model transformation. Our aim is to generate at run-time a dynamic model transformation, because the rules describing their behavior are not pre set but are selected from a repository depending on the context. The proposal describes an adaptation schema based on model transformation providing a solution to this dynamic transformation. Context information is processed to select at run-time a rule subset from a repository. Selected rules are used to generate, through a higher-order transformation, the dynamic model transformation. This approach has been tested through a case study which applies different repositories to the same architecture and context. Moreover, a web tool has been developed for validation and demonstration of its applicability. The novelty of our proposal arises from the adaptation schema that creates a non pre-set transformation, which enables the dynamic adaptation of component-based architectures

Toward the adaptation of component-based architectures by model transformation: behind smart user interfaces

Graphical user interfaces are not always developed for remaining static. There are GUIs with the need of implementing some variability mechanisms. Component-based GUIs are an ideal target for incorporating this kind of operations, because they can adapt their functionality at run-time when their structure is updated by adding or removing components or by modifying the relationships between them. Mashup user interfaces are a good example of this type of GUI, and they allow to combine services through the assembly of graphical components. We intend to adapt component based user interfaces for obtaining smart user interfaces. With this goal, our proposal attempts to adapt abstract component-based architectures by using model transformation. Our aim is to generate at run-time a dynamic model transformation, because the rules describing their behavior are not pre set but are selected from a repository depending on the context. The proposal describes an adaptation schema based on model transformation providing a solution to this dynamic transformation. Context information is processed to select at run-time a rule subset from a repository. Selected rules are used to generate, through a higher-order transformation, the dynamic model transformation. This approach has been tested through a case study which applies different repositories to the same architecture and context. Moreover, a web tool has been developed for validation and demonstration of its applicability. The novelty of our proposal arises from the adaptation schema that creates a non pre-set transformation, which enables the dynamic adaptation of component-based architectures

A review of energy measurement approaches

International audienceReducing the energy footprint of digital devices and software is a task challenging the research in Green IT. Researches have proposed approaches for energy management, ranging from reducing usage of software and hardware, compilators optimization, to server consolidation and software migration. However, optimizing the energy consumption requires knowledge of that said consumption. In particular, measuring the energy consumption of hardware and software is an important requirement for efficient energy strategies. In this review, we outline the different categories of approaches in energy measurements, and provide insights into example of each category. We draw recommendations from our review on requirements on how to efficiently measure energy consumption of devices and software

Syndrome de Sneddon avec anticorps anti-mitochondries de type M5

International audienceAntimitochondrial type M5 antibodies (AMA-M5) are among the immunological abnormalities associated with Sneddon syndrome. Case A 45 year-old woman, hospitalized for diplopia and with a 20-year history of obstetrical accidents, internuclear ophthalmoplegia and livedo, was diagnosed with Sneddon syndrome associated with primary antiphospholipid syndrome (APS) aggravated by the presence of AMA-M5. Discussion AMA-M5 are immunological markers of APS to the same extent as antiphospholipid antibodies. This case demonstrates the interest of screening for AMA-M5 in cases of strong clinical suspicion of APS when the anticoagulant lupus test is normal and no anti-cardiolipin, anti-b2 glycoprotein I or antiprothrombin antibodies are found

VI. Forces et comportements politiques en France

VI. Forces et comportements politiques en France. In: Revue française de science politique, 30ᵉ année, n°3, 1980. pp. 697-698