The role of teachers’ motivation and mindsets in predicting a (de)motivating teaching style in higher education : a circumplex approach

Although different measures for (de)motivating teaching are available for primary and secondary education, a fine-grained instrument to assess a variety of motivating and demotivating teaching practices in higher education is lacking. Adopting a Self-Determination Theory perspective, this study first used the newly developed Situation-in-School Questionnaire—Higher Education to examine in a sample of higher education teachers (N = 357; Mage = 43.90 years) whether a broad set of need-supportive and need-thwarting teaching practices are organized in a similar circular structure as in secondary education (Aelterman et al. in J Educ Psychol 111:497–521, 2019). Second, this study addressed the role of higher education teachers’ motivation to teach (i.e., autonomous, controlled, amotivation) and their beliefs about the malleability of students’ intelligence (i.e., fixed and growth mindset) in relation to the various distinguished teaching approaches. Results of multidimensional scaling analyses confirmed the hypothesized circular structure of eight different (de)motivating teaching approaches that differ in their level of need-supportiveness and directiveness. Second, hierarchical regression analyses provided evidence for the fairly independent role of teachers’ motivation and mindsets, with the predictive role of each predictor systematically varying as one moves along the circumplex. Autonomous motivation and a growth mindset related positively to more motivating approaches (e.g., guiding, attuning), while controlled motivation, amotivation and a fixed mindset related positively to more demotivating approaches (e.g., domineering, abandoning). The present findings shed new light on the factors that underlie teacher-reported engagement in (de)motivating practices in higher education

A tutorial mini-review on nanoporous carbons from biosourced building blocks: ordered hierarchical nanoarchitectures through benign methodologies

Ordered hierarchically porous carbons exhibiting micro- and mesopores are state-of-the-art porous structures with extraordinary performance in a range of applications (e.g., electrochemistry, catalysis, water treatment). Nevertheless, they are mostly prepared using petroleum-based chemicals, through resource- and energy-intensive, environmentally unfriendly processes. In this tutorial mini-review, we highlight major limitations in the methodologies, and showcase important achievements towards developing more sustainable synthetic strategies. Compared to multi-step hard-templating/nano-casting procedures, soft-templating techniques can provide more efficient, benign, and direct ways to produce these nanostructures. The original soft-templating method, using Pluronic® surfactants as structure-directing agents and phenolic resins as carbon precursors, has been substantially modified over the years in light of sustainability issues. The formaldehyde crosslinker has been replaced with more benign, less toxic alternatives (e.g., glyoxal), and catalyst-free crosslinking approaches have been developed. Furthermore, the use of biobased building-blocks for the carbon precursor, such as lignin, plant-derived polyphenols (e.g., tannins), and various saccharides (e.g., D-glucose, D-fructose), has also been explored. Novel techniques, such as the coordination-induced self-assembly, mechanosynthesis, and modified hydrothermal treatment strategies are amongst the greenest processes developed so far. We give some critical comments on ongoing research in this field and point towards interesting research directions

The 15q24/25 Susceptibility Variant for Lung Cancer and Chronic Obstructive Pulmonary Disease Is Associated with Emphysema

RATIONALE: Genome-wide association studies have identified genetic variants in the nicotinic acetylcholine receptor (nAChR) on chromosome 15q24/25 as a risk for nicotine dependence, lung cancer and chronic obstructive pulmonary disease (COPD). Assessment of bronchial obstruction by spirometry, typically used for diagnosing COPD, fails, however, to detect emphysema. OBJECTIVES: To determine the association of the 15q24/25 locus with emphysema. METHODS: The rs1051730 variant on 15q24/25 was genotyped in two independent Caucasian cohorts of 661 and 456 heavy smokers. Participants underwent pulmonary function tests, computed tomography (CT) of the chest and took questionnaires assessing smoking behaviour and health status. MEASUREMENTS AND MAIN RESULTS: The rs1051730 A-allele correlated with reduced forced expiratory volume in 1 second (FEV1) and with increased susceptibility for bronchial obstruction with a pooled odds ratio (OR) of 1.33 (95% confidence interval [CI]=1.11-1.61; P=0.0026). In both studies a correlation between the rs1051730 A-allele and lung diffusing capacity (DLCO) and diffusing capacity per unit alveolar volume (KCO) was observed. Consistently, the rs1051730 A-allele conferred increased risk for emphysema as assessed by CT (P=0.0097 and P=0.019), with a pooled OR of 1.39 (CI=1.15-1.68; P=0.00051). Visual emphysema scores and scores based on densities quantified on CT were more pronounced in A-allele carriers, indicating that rs1051730 correlates with the severity of emphysema. CONCLUSIONS: The 15q24/25 locus in nAChR is associated with the presence and severity of emphysema. This association was independent of pack-years smoking, suggesting that nAChR is causally involved in alveolar destruction, as a potentially shared pathogenic mechanism in lung cancer and COPD.status: publishe

The 15q24/25 Susceptibility Variant for Lung Cancer and Chronic Obstructive Pulmonary Disease Is Associated with Emphysema

Rationale: Genome-wide association studies have identified genetic variants in the nicotinic acetylcholine receptor (nAChR) on chromosome 15q24/25 as a risk for nicotine dependence, lung cancer, and chronic obstructive pulmonary disease (COPD). Assessment of bronchial obstruction by spirometry, typically used for diagnosing COPD, fails, however, to detect emphysema. Objectives: To determine the association of the 15q24/25 locus with emphysema. Methods: The rs1051730 variant on 15q24/25 was genotyped in two independent white cohorts of 661 and 456 heavy smokers. Participants underwent pulmonary function tests and computed tomography (CT) of the chest, and took questionnaires assessing smoking behavior and health status. Measurements and Main Results: The rs1051730 A-allele correlated with reduced FEV(1) and with increased susceptibility for bronchial obstruction with a pooled odds ratio (OR) of 1.33 (95% confidence interval [CI] = 1.11-1.61; P = 0.0026). In both studies a correlation between the rs1051730 A-allele and lung diffusing capacity (DL(CO)) and diffusing capacity per unit alveolar volume (KCO) was observed. Consistently, the rs1051730 A-allele conferred increased risk for emphysema as assessed by CT (P = 0.0097 and P = 0.019), with a pooled OR of 1.39 (CI = 1.15-1.68; P = 0.00051). Visual emphysema scores and scores based on densities quantified on CT were more pronounced in A-allele carriers, indicating that rs1051730 correlates with the severity of emphysema. Conclusions: The 15q24/25 locus in nAChR is associated with the presence and severity of emphysema. This association was independent of pack-years smoking, suggesting that nAChR is causally involved in alveolar destruction as a potentially shared pathogenic mechanism in lung cancer and COPD

A prospective multi-centre study of the value of FDG-PET as part of a structured diagnostic protocol in patients with fever of unknown origin.

Contains fulltext : 52019.pdf (publisher's version ) (Closed access)PURPOSE: Since (18)F-fluorodeoxyglucose (FDG) accumulates in neoplastic cells and in activated inflammatory cells, positron emission tomography (PET) with FDG could be valuable in diagnosing patients with fever of unknown origin (FUO). The aim of this study was to validate the use of FDG-PET as part of a structured diagnostic protocol in the general patient population with FUO. METHODS: From December 2003 to July 2005, 70 patients with FUO were recruited from one university hospital (n=38) and five community hospitals (n=32). A structured diagnostic protocol including FDG-PET was used. A dedicated, full-ring PET scanner was used for data acquisition. FDG-PET scans were interpreted by two staff members of the department of nuclear medicine without further clinical information. The final clinical diagnosis was used for comparison with the FDG-PET results. RESULTS: Of all scans, 33% were clinically helpful. The contribution of FDG-PET to the final diagnosis did not differ significantly between patients diagnosed in the university hospital and patients diagnosed in the community hospitals. FDG-PET contributed significantly more often to the final diagnosis in patients with continuous fever than in patients with periodic fever. FDG-PET was not helpful in any of the patients with normal erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP). CONCLUSION: FDG-PET is a valuable imaging technique as part of a diagnostic protocol in the general patient population with FUO and a raised ESR or CRP