284 research outputs found

    How to manage and minimize food waste in the hotel industry? An exploratory research

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    Purpose – The hospitality industry is responsible for significant amounts of waste, more than one-third of which is food waste. Through the comparison between an Italian and a Romanian hotel, this paper aims to provide a better understanding of food waste management trends in the hotel industry as well as to highlight hotel kitchens and hotel food services weaknesses and opportunities to minimize food waste. Design/methodology/approach – In-depth interviews, personal communication and observations were conducted to investigate food service planning, food procurement and food waste management, as well as to better comprehend current individuals’ understanding and attitudes, infrastructures, legislative culture and opportunities either from the managerial and the employees’ perspective. Data were analyzed according to a content analysis approach. Findings – Three critical hot spots emerged from the analysis: prediction and check of guests’ attendance, communication and transparency with local suppliers and among departments within the unit and purchasing frequency and perishable food provisioning. The accurate forecasting of the number of guests and their nationality is fundamental in avoiding food waste at food service, as well as implementing transparency and communication with local suppliers. Originality/value – Although academia and authorities have recognized the crucial importance of food waste management, food waste research in the hotel industry remains under-researched. The present exploratory research contributes to the scarce empirical studies about hotels’ food waste, giving theoretical and managerial recommendations for supporting further studies, highlighting the need for formal deals between hotels and local suppliers (food procurement), as well as the importance of foodnetworks that holds together companies, retailers and charities (food donation)

    Geometric and homological finiteness in free abelian covers

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    We describe some of the connections between the Bieri-Neumann-Strebel-Renz invariants, the Dwyer-Fried invariants, and the cohomology support loci of a space X. Under suitable hypotheses, the geometric and homological finiteness properties of regular, free abelian covers of X can be expressed in terms of the resonance varieties, extracted from the cohomology ring of X. In general, though, translated components in the characteristic varieties affect the answer. We illustrate this theory in the setting of toric complexes, as well as smooth, complex projective and quasi-projective varieties, with special emphasis on configuration spaces of Riemann surfaces and complements of hyperplane arrangements.Comment: 30 pages; to appear in Configuration Spaces: Geometry, Combinatorics and Topology (Centro De Giorgi, 2010), Edizioni della Normale, Pisa, 201

    Complication rates in managing hepatic trauma: a cross-sectional study stratifying their outcomes

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    Background: Liver trauma is the most commonly observed injured organ in abdominal trauma. The objectives of this study was to determine and evaluate the rates of complication in the management of liver traumaMethods: This cross-sectional observational study using non-probability convenient sampling technique was done at surgical unit of Liaquat University of Medical and Health Sciences, Jamshoro, for 06 months. After ethical approval from Institute’s Institutional Review Board (IRB), patients presenting to surgical emergency of the hospital between ages 16 to 60 years having blunt or penetrating liver trauma within 04 hours of incident, either road traffic accident, sustaining a fall, sporting injury, knife or stab wound were include while patients of liver trauma conservatively managed or had severe co-morbid, not fit for anesthesia, with multiple organs lesions (polytrauma) and all hepatic injury patients that were hemo-dynamically stable were excluded. SPSS version 23 was used for data analysis keeping p-value <0.05 as significant.Results: Among 136 patients with mean age 32.33±11.23 years, 120(88.2%) were males. 122(89.7%) of the patients were admitted due to liver trauma of blunt variety while 14(10%) with penetrating liver injury. Overall mean duration of hospital stay was 13.1±4.58 days. 41(30%) patients reported intra-abdominal sepsis, followed by recurrent hemorrhage in 33(24%) of patients while in 22(16%) of patients, biliary leakage was observed. An insignificant difference persisted in either surgical intervention in terms of the complication rates.Conclusions: Higher complication rates were observed in patients with peri-hepatic packing, however outcome of both surgical techniques in terms of complication rates were found to be insignificant. Further studies are needed to shed light upon the findings or this study

    Dynamic Profiling of ÎČ-Coronavirus 3CL Mpro Protease Ligand-Binding Sites

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    ÎČ-coronavirus (CoVs) alone has been responsible for three major global outbreaks in the 21st century. The current crisis has led to an urgent requirement to develop therapeutics. Even though a number of vaccines are available, alternative strategies targeting essential viral components are required as a backup against the emergence of lethal viral variants. One such target is the main protease (Mpro) that plays an indispensable role in viral replication. The availability of over 270 Mpro X-ray structures in complex with inhibitors provides unique insights into ligand-protein interactions. Herein, we provide a comprehensive comparison of all nonredundant ligand-binding sites available for SARS-CoV2, SARS-CoV, and MERS-CoV Mpro. Extensive adaptive sampling has been used to investigate structural conservation of ligand-binding sites using Markov state models (MSMs) and compare conformational dynamics employing convolutional variational auto-encoder-based deep learning. Our results indicate that not all ligand-binding sites are dynamically conserved despite high sequence and structural conservation across ÎČ-CoV homologs. This highlights the complexity in targeting all three Mpro enzymes with a single pan inhibitor

    Opening the Gate:Framework Flexibility in ZIF-8 Explored by Experiments and Simulations

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    ZIF-8 is a zeolitic imidazole-based metal-organic framework with large cavities interconnected by narrow windows. Because the small size of the windows, it allows in principle for molecular sieving of gases such as H-2 and CH4. However, the unexpected adsorption of large molecules on ZIF-8 suggests the existence of structural flexibility. ZIF-8 flexibility is explored in this work combining different experimental techniques with molecular simulation. We show that the ZIF-8 structure is modified by gas adsorption uptake in the same way as it is at a very high pressure (i.e., 14 700 bar) due to a swing effect in the imidazolate linkers, giving access to the porosity. Tuning the flexibility, and so the opening of the small windows, has a further impact on the design of advanced molecular sieving membrane materials for gas separation, adjusting the access of fluids to the porous network.</p

    Controlled generation of momentum states in a high-finesse ring cavity

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    A Bose-Einstein condensate in a high-finesse ring cavity scatters the photons of a pump beam into counterpropagating cavity modes, populating a bi-dimensional momentum lattice. A high-finesse ring cavity with a sub-recoil linewidth allows to control the quantized atomic motion, selecting particular discrete momentum states and generating atom-photon entanglement. The semiclassical and quantum model for the 2D collective atomic recoil lasing (CARL) are derived and the superradiant and good-cavity regimes discussed. For pump incidence perpendicular to the cavity axis, the momentum lattice is symmetrically populated. Conversely, for oblique pump incidence the motion along the two recoil directions is unbalanced and different momentum states can be populated on demand by tuning the pump frequency.Comment: Submitted to EPJ-ST Special Issue. 10 pages and 3 figure

    Reductive electrosynthesis of crystalline metal-organic frameworks

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    Electroreduction of oxoanions affords hydroxide equivalents that induce selective deposition of crystalline metal–organic frameworks (MOFs) on conductive surfaces. The method is illustrated by cathodic electrodeposition of Zn[subscript 4]O(BDC)[subscript 3] (MOF-5; BDC = 1,4-benzenedicarboxylate), which is deposited at room temperature in only 15 min under cathodic potential. Although many crystalline phases are known in the Zn[superscript 2+]/BDCsuperscript 2–] system, MOF-5 is the only observed crystalline MOF phase under these conditions. This fast and mild method of synthesizing MOFs is amenable to direct surface functionalization and could impact applications requiring conformal coatings of microporous MOFs, such as gas separation membranes and electrochemical sensors.Massachusetts Institute of Technology. Energy Initiative (Seed Fund Program)National Science Foundation (U.S.) (Grant CHE-9808061)National Science Foundation (U.S.) (Grant DBI-9729592)National Science Foundation (U.S.) (Grant DMR- 0819762

    Educational paper: Defects in number and function of neutrophilic granulocytes causing primary immunodeficiency

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    The neutrophilic granulocyte (neutrophil) is the most important cellular component of the innate immune system. A total absence of neutrophils or a significant decrease in their number leads to severe immunodeficiency. A mature neutrophil, released from the bone marrow, should be able to migrate from the blood towards the tissues, following a chemotactic gradient to a pathogen. In order to be neutralized, this pathogen has to be recognized, phagocytosed, and destroyed by lytic enzymes contained in the neutrophil's granules and reactive oxygen species formed by the enzyme complex NADPH oxidase. Rare genetic defects leading to the loss of each one of these biological properties of the neutrophil have been described and are associated with immunodeficiency. This review provides a summary of the normal development and biological functions of neutrophils and describes the diseases caused by defects in neutrophil number and function
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