Waste Management System in Karachi as an Environmental and Health Hazard

Present research is an attempt to describe the problem of waste management of Karachi and its possible impact as a health hazardous issue in the city. The study mainly focuses on the issues of solid waste management in the sampled areas of Defence Housing Authority (DHA) Karachi and Cantonment Board Clifton (CBC). A poll result shows that the sewerage management is comparatively better than the other areas. However, additional and adequate waste management measures to overcome some problems faced in solid as well as effluent disposal.   Conditions in the waste management system can be improved if all the concerned departments worked on a policy of mutual co-operation and co-ordination. This will not only ensure healthier and efficient system but also provide incentive for improvement to areas other than the sampled area. Keywords: Solid Waste Management, Clifton Cantonment Board, Environmental Decency, General Welfare. DOI: 10.7176/PPAR/9-4-07 Publication date: April 30th 201

Fabrication of Ag and Ni Nanocatalyst with Enhanced Efficiency

Metal nanoparticles (NPs) have received significant attention in last decade because of their unique properties. In this work, two different metal NPs have been prepared and their catalytic activities are compared with conventional catalyst. In first case, Ag NPs were synthesized by chemical reduction method in ethanolic medium. Synthesized Ag NPs were characterized by scanning electron microscope (SEM) images which indicated an average particle size of Ag around 250 nm. The catalytic activity of Ag NPs was investigated for the oxidative mineralization of methylene blue dye. Comparative studies suggested that Ag NPs possess enhanced catalytic activity compared to bulk Ag. In second approach, supported Ni NPs were fabricated using Al2O3 as supporting surface; that is, Ni NPs get adsorbed on Al2O3 through in situ reduction reaction. Oxidative degradation of methylene blue indicated that catalytic activity of supported Ni/Al2O3 is about five times higher than simple Ni as catalyst

2023 Supplementary Immunization Coverage Survey in Super High Risk Union Councils of Pakistan (TPVICS-SHRUCs Rounds 1-3)

• Background and Objectives• Survey Design and Methods• Survey Results• Behavioral and Social Drivers of Vaccination (BeSD)• Discussion• Referenceshttps://ecommons.aku.edu/pakistan_coe-wch_survey_report/1002/thumbnail.jp

A Study of Big Data for Business Growth in SMEs: Opportunities & Challenges

In today's world the data is considered as an extremely valued asset and its volume is increasing exponentially every day. This voluminous data is also known as Big Data. The Big Data can be described by 3Vs: the extreme Volume of data, the wide Variety of data types, and the Velocity required processing the data. Business companies across the globe, from multinationals to small and medium enterprises (SMEs), are discovering avenues to use this data for their business growth. In order to bring significant change in businesses growth the use of Big Data is foremost important. Nowadays, mostly business organization, small or big, wishes valuable and accurate information in decision-making process. Big data can help SMEs to anticipate their target audience and customer preferences and needs. Simply, there is a dire necessity for SMEs to seriously consider big data adoption. This study focusses on SMEs due to the fact that SMEs are backbone of any economy and have ability and flexibility for quicker adaptation to changes towards productivity. The big data holds different contentious issues such as; suitable computing infrastructure for storage, processing and producing functional information from it, and security and privacy issues. The objective of this study is to survey the main potentials & threats to Big Data and propose the best practices of Big Data usage in SMEs to improve their business process

A Study of Big Data for Business Growth in SMEs: Opportunities & Challenges

In today's world the data is considered as an extremely valued asset and its volume is increasing exponentially every day. This voluminous data is also known as Big Data. The Big Data can be described by 3Vs: the extreme Volume of data, the wide Variety of data types, and the Velocity required processing the data. Business companies across the globe, from multinationals to small and medium enterprises (SMEs), are discovering avenues to use this data for their business growth. In order to bring significant change in businesses growth the use of Big Data is foremost important. Nowadays, mostly business organization, small or big, wishes valuable and accurate information in decision-making process. Big data can help SMEs to anticipate their target audience and customer preferences and needs. Simply, there is a dire necessity for SMEs to seriously consider big data adoption. This study focusses on SMEs due to the fact that SMEs are backbone of any economy and have ability and flexibility for quicker adaptation to changes towards productivity. The big data holds different contentious issues such as; suitable computing infrastructure for storage, processing and producing functional information from it, and security and privacy issues. The objective of this study is to survey the main potentials & threats to Big Data and propose the best practices of Big Data usage in SMEs to improve their business process

A Study of Big Data for Business Growth in SMEs: Opportunities & Challenges

In today's world the data is considered as an extremely valued asset and its volume is increasing exponentially every day. This voluminous data is also known as Big Data. The Big Data can be described by 3Vs: the extreme Volume of data, the wide Variety of data types, and the Velocity required processing the data. Business companies across the globe, from multinationals to small and medium enterprises (SMEs), are discovering avenues to use this data for their business growth. In order to bring significant change in businesses growth the use of Big Data is foremost important. Nowadays, mostly business organization, small or big, wishes valuable and accurate information in decision-making process. Big data can help SMEs to anticipate their target audience and customer preferences and needs. Simply, there is a dire necessity for SMEs to seriously consider big data adoption. This study focusses on SMEs due to the fact that SMEs are backbone of any economy and have ability and flexibility for quicker adaptation to changes towards productivity. The big data holds different contentious issues such as; suitable computing infrastructure for storage, processing and producing functional information from it, and security and privacy issues. The objective of this study is to survey the main potentials & threats to Big Data and propose the best practices of Big Data usage in SMEs to improve their business process

Effects of a high-dose 24-h infusion of tranexamic acid on death and thromboembolic events in patients with acute gastrointestinal bleeding (HALT-IT): an international randomised, double-blind, placebo-controlled trial

Background: Tranexamic acid reduces surgical bleeding and reduces death due to bleeding in patients with trauma. Meta-analyses of small trials show that tranexamic acid might decrease deaths from gastrointestinal bleeding. We aimed to assess the effects of tranexamic acid in patients with gastrointestinal bleeding. Methods: We did an international, multicentre, randomised, placebo-controlled trial in 164 hospitals in 15 countries. Patients were enrolled if the responsible clinician was uncertain whether to use tranexamic acid, were aged above the minimum age considered an adult in their country (either aged 16 years and older or aged 18 years and older), and had significant (defined as at risk of bleeding to death) upper or lower gastrointestinal bleeding. Patients were randomly assigned by selection of a numbered treatment pack from a box containing eight packs that were identical apart from the pack number. Patients received either a loading dose of 1 g tranexamic acid, which was added to 100 mL infusion bag of 0·9% sodium chloride and infused by slow intravenous injection over 10 min, followed by a maintenance dose of 3 g tranexamic acid added to 1 L of any isotonic intravenous solution and infused at 125 mg/h for 24 h, or placebo (sodium chloride 0·9%). Patients, caregivers, and those assessing outcomes were masked to allocation. The primary outcome was death due to bleeding within 5 days of randomisation; analysis excluded patients who received neither dose of the allocated treatment and those for whom outcome data on death were unavailable. This trial was registered with Current Controlled Trials, ISRCTN11225767, and ClinicalTrials.gov, NCT01658124. Findings: Between July 4, 2013, and June 21, 2019, we randomly allocated 12 009 patients to receive tranexamic acid (5994, 49·9%) or matching placebo (6015, 50·1%), of whom 11 952 (99·5%) received the first dose of the allocated treatment. Death due to bleeding within 5 days of randomisation occurred in 222 (4%) of 5956 patients in the tranexamic acid group and in 226 (4%) of 5981 patients in the placebo group (risk ratio [RR] 0·99, 95% CI 0·82–1·18). Arterial thromboembolic events (myocardial infarction or stroke) were similar in the tranexamic acid group and placebo group (42 [0·7%] of 5952 vs 46 [0·8%] of 5977; 0·92; 0·60 to 1·39). Venous thromboembolic events (deep vein thrombosis or pulmonary embolism) were higher in tranexamic acid group than in the placebo group (48 [0·8%] of 5952 vs 26 [0·4%] of 5977; RR 1·85; 95% CI 1·15 to 2·98). Interpretation: We found that tranexamic acid did not reduce death from gastrointestinal bleeding. On the basis of our results, tranexamic acid should not be used for the treatment of gastrointestinal bleeding outside the context of a randomised trial

Chronic low-grade postoperative endophthalmitis in a child with Marfan syndrome

Darakhshanda Khurram Butt,1 Robert A Scott,1,2 Muralidharan R Upendran1 1Moorfields Eye Hospital, Dubai, UAE; 2SpaMedica, Manchester, UK Abstract: This case report describes a 9-year-old male who presented to the emergency department with 2 days’ history of left painful red eye. On initial examination, his outside medical records indicated that he had bilateral subluxated lenses and had undergone left eye lensectomy with glued intrascleral fixation of an intraocular lens 8 weeks earlier. Vision in left eye was poor from first postoperative day but with no undue pain or redness, and poor vision was attributed to possible vitreous bleed. Subsequent postoperative course was uneventful. He was discharged from ophthalmic care on topical steroids and antibiotic drops, one week postsurgery. The eye was healing well until he developed pain, for which ophthalmic care was sought. He underwent anterior chamber tap with intravitreal injections. Aqueous samples were positive for Staphylococcus aureus DNA by polymerase chain reaction. Post vitrectomy and implant removal, his recovery was good and vision improved to 0.50 LogMar with aphakic correction. Keywords: glued intrascleral fixation IOL, subluxated lens, post-op endophthalmiti