Outreach program at the Scripps Institution of Oceanography Library: targeting faculty, researchers, and students

pp. 47-5

Managing information: evaluating and selecting citation management software, a look at EndNote, RefWorks, Mendeley and Zotero

pp. 53-6

Demographic and trend analysis of COVID-19 test results of Boone County, Missouri

The COVID-19 pandemic has had a deep influence on American life. However, the burden of the COVID-19 pandemic has not been distributed equally among members of a population based on their demographic features. The purpose of this study was to investigate whether sex, age, race/ethnicity, and religion were associated with COVID-19 testing and positivity rates in Boone County, Missouri for 22 months period (March 2020 to December 2021) of the pandemic. We analyzed the data using age distribution histograms with each demographic feature. We also computed two-way delta tables to highlight our study findings. These tables show that males with 0.012 delta percentage are significantly more likely to test COVID positive than females with -0.015 delta percentage. Black or African American "NONE" of 0.0072 delta percentage are significantly more likely to test COVID positive than White individuals of -0.0075 delta percentage. Our study results supported the hypothesis that males and minority races such as Black or African American and All-Other are more likely to test positive for COVID-19. Additionally, we analyzed the data using the trend analysis graphs with each demographic feature across a collection of defined epochs of key events, such as vaccine release, delta variant, vaccine boosters, and omicron. Our study results supported the hypothesis that males and minority races such as Black or African Americans and All-Other are more likely to have a higher COVID-19 positivity rate across our defined epochs. Additionally, we explore interesting deviations between demographics within various epochs.Includes bibliographical references

Current difficulties and recent advances in bypass therapy for the management of hemophilia with inhibitors: a new and practical formulation of recombinant factor VIIa

Bypassing agents are the mainstay of treatment for patients with hemophilia with high-titer inhibitors. Whereas the availability of these agents has greatly advanced the management of bleeding episodes in this population, timely administration of bypassing agents continues to be hampered by a number of practical limitations, including the need for refrigerated storage of the agent and its reconstitution at room temperature prior to administration, among others. In this review, the importance of early treatment of bleeds and factors that influence this more timely therapeutic approach are highlighted, together with the advantages offered by the use of a new formulation of recombinant activated factor VII that permits improved storage and portability, potentially optimizing timely bypassing agent administration

STRATEGI PROGRAM “MAJA LEWU” PEMERINTAH KOTA PALANGKA RAYA PROVINSI KALIMANTAN TENGAH DALAM MENCIPTAKAN HUBUNGAN YANG HARMONIS DENGAN MASYARAKAT

The society much played roles and affected an institutional viability. The success of an institution depended on society roles and how the institution managed its relationship with the society was. To create a harmonious relationship, there should be an understanding to each other and also to besuccessful of the government and development, the regional government also communicated to the society. This research was aimed to know how Maja Lewu program strategy in Society Empowerment Board Department of Palangka Raya City was. This research used a descriptive qualitative method. The method was used to describe and to analyze Maja Lewu program strategy in Society Empowerment Board Department of Palangka Raya City. Data was obtained through an interview with Society Empowerment Board of Palangka Raya City and the society, and also supported by documentation. In the program enforcement, BPM as an executive firstly established a committee. BPM also determined Maja Lewu program target namely all village heads in Palangka Raya by prioritizing the under-developed village heads and also under-poverty-line regions. BPM also invited all Office Heads, Governor and Governor Deputy to attend this program. During program was enforced, it was conducted a dialog between the government and the society, all village heads society could express their aspiration directly to the government. Besides the dialog, there was also entertainment and health service. The dialog results could be materialized by the government with some consideration. BPM also evaluated to find out program obstacles, program supporting factors and also efforts to overcome the obstacles. Therefore, it could be learning in order that this program could run better in the future

Exploring Factors Contributing to Injury Severity at Freeway Merging and Diverging Locations in Ohio

Identifying factors that affect crash injury severity and understanding how these factors affect injury severity is critical in planning and implementing highway safety improvement programs. Factors such as driver-related, traffic-related, environment-related and geometric design-related were considered when developing statistical models to predict the effects of these factors on the severity of injuries sustained from motor vehicle crashes at merging and diverging locations. Police-reported crash data at selected freeway merging and diverging areas in the state of Ohio were used for the development of the models. A generalized ordinal logit model also known as partial proportional odds model was applied to identify significant factors increasing the likelihood of one of the five KABCO scale of injury severity: no injuries, possible/invisible injuries, non-incapacitating injuries, incapacitating injuries, or fatal injuries. The results of this study show that semi-truck related crashes, higher number of lanes on freeways, higher number of lanes on ramps, speeding related crashes, and alcohol related crashes tend to increase the likelihood of sustaining severe injuries at freeway merging locations. In addition, females and older persons are more likely to sustain severe injuries especially at freeway merge locations. Alcohol related crashes, speeding related crashes, angle-type collisions, and lane-ramp configuration type D significantly increase the likelihood of severe injury crashes at diverging areas. Poor lighting condition tends to increase non-incapacitating injuries at diverging areas only. Moreover, adverse weather condition increases the likelihood of no-injury and fatal injuries at merging areas only and adverse road conditions tend to increase a range of injury severity levels from possible/invisible injuries to incapacitating injuries at merging areas only. Highlights Semi-truck, lanes on freeways and ramps, speeding, angle collisions, and alcohol increase severe injuries at merging areas. Females and older persons sustain severe injuries at freeway merge locations. Alcohol, speeding, angle collisions, and lane-ramp type D increase severe injuries at diverging areas. Adverse weather condition increases no-injury and fatal injuries at merging areas only. Adverse road condition tends to increase a range of non-fatal injury levels at merging areas only

TUGAS AKHIR PERANCANGAN INFRASTRUKTUR DARI ASPEK STRUKTUR, KEAIRAN, DAN MANAJEMEN KONSTRUKSI (STUDI KASUS: PERANCANGAN BANGUNAN GEDUNG 3 LANTAI DI KOTA SURAKARTA)

Laporan tugas Akhir perancangan infrastruktur II meliputi praktik perancangan gedung (PPBA), praktik perancangan jalan (PPJ), praktik perancangan bangunan air (PPBA), dan praktik perancangan biaya dan waktu. Bangunan gudung adalah Bangunan yang bersifat khusus dan berfungsi untuk keperluan aktivitas manusia. Perancangan bangunan gedung yang dilakukan umumnya perlu memenuhi persyaratan SNI , sehingga dapat dikatakan aman.Perancangan ini mengacu pada SNI 2847:2013 tentang beton bertulang , SNI 1726:2012 tentang gempa, SNI 1727:2013 tentang pembebanan dan SNI 1729:2015 tentang baja. Perancangan bangunan gedung ini meliputi atap, tangga, pelat, balok, kolom, sloof, dan pondasi. Analisis perancangan dilakukan dengan mengunakan software ETABS dan SAP2000, selain itu ada pula software pendukung seperti IKOLAT 2000 dan Autocad. Untuk estimasi dimensi yang dilakukan telah memperhitungkan beban yang diterima oleh banguan seperti beban hidup, beban mati, beban angin dan beban gempa. Hasil yang diperoleh dari perancangan ini berupa hasil desain struktur yang telah memenihi syarat keamanan menutur SNI yang digunakan. Pada Praktik Perancangan jalan, perancangan yang dilakukan berupa survey dan perhitungan pejalan kaki, zebra cross, volume kendaraan, waktu tempuh kendaraan, on road, off road dan zona selamat sekolah. Hasil dari Survey ini digunakan untuk merencanakan tebal perkerasan ,menetukan kelayakan fasilitas pejalan kaki dan kapasitas parkir kendaraan motor. Perancangan bangunan air ini berupa perancangan bendung.Bendung yang ditinjau yaitu bendung Grembyangan. Perancangan bedung yang dilakukan berupa analisis curah hujan dari daerah DAS yang di tinjau guna merancang struktur bedung yang sesuai dengan syarat keamanan terhadap gaya geser, gaya guling, angkat, rembesan dan gempa.Berdasarkan Hasil dari perancangan,dapat disimpulakan bedung yang direncanakan telah memenuhi syarat keamanan terhadap gaya geser, gaya gulung, gaya angkat, dan daya dukung tanah . Pada pembangunan suatu bangunan, perencanaan pembiayaan dan penjadwalan dibutuhkan sebelum bangunan dibangun, sehingga jumlah biaya yang akan dikeluarkan dan lamanya durasi waktu pekerjaan dapat diperkirakan oleh perencana. Perencanaan biaya dan waktu yang dilakukan berupa perbandingan anggaran biaya dan waktu pada pembanguna rumah tinggal 2 lantai di Sleman yang mengunakan harga satuan Provinsi Yogyakarta dan harga satuan Provinsi Papuan. Berdasarkan hasil Perencanaan ,RAB dari harga satuan Provinsi Yogjakarta sebesar Rp 1,021,859,000.00. lebih kecil dibanding RAB dari harga satuan Provinsi Papuan. Perbedaan harga yang cukup jauh dipengaruhi oleh harga bahan dan upah pekerja yang sagat jauh. Dan untuk durasi pekerjaan adalah 6 bulan

Response of polycaprolactone bone scaffolds with -hydroxyapatite and tricalcium phosphate to elevated loading frequencies

Introduction: Recent studies have implied that bone cells respond more favorably to low amplitude loading at higher frequencies in contrast to high amplitude loading at low frequencies. However, the mechanical response associated with bone scaffolds at elevated frequency loading is unknown. The goal of this study was to evaluate the performance of polycaprolactone (PCL) bone scaffold materials with hydroxyapatite (HA) and tricalcium phosphate (TCP) under various loading frequencies. Materials and Methods: Compression molded scaffolds containing polycaprolactone scaffolds with 14% hydroxyapatite (HA) or 14% tricalcium phosphate (TCP) were fabricated. Scaffolds were subjected to cyclic compressive loading from –0.5 N to –2 N for 535 loading cycles at 1 Hz (N = 12HA, N = 12TCP), 2.5 Hz (N = 12HA, N = 12TCP), 5 Hz (N = 6HA, N = 6TCP), and 7.5 Hz (N=12 HA, N=12 TCP). Compressive loads were applied using a 1-mm diameter indentor mounted to the actuator of a materials testing machine. Load versus deformation data were acquired at cycle 10 and at 25 cycle intervals thereafter. For each scaffold type, deformation changes over the applied loading cycles were calculated for each test site and subjected to nonlinear exponential regression. The resulting exponential parameters included Y0 (initial deformation) and K (rate of deformation change per cycle) and were analyzed using a one-way ANOVA with a Tukey posthoc test for differences between scaffold types and loading frequency. Results and Discussion: Statistically significant differences in the initial deformation, Y0, were found across both material type (HA versus TCP) and loading frequency. (P \u3c 0.05 for all comparisons). For a given frequency, with the exception of 7.5 Hz, TCP scaffolds displayed significantly elevated initial deformation when compared with HA, indicative of a decreased modulus relative to HA. For the K values, statistically significant increases in K value were found for both HA and TCP scaffolds when loaded at 7.5 Hzwhen compared with all other frequencies (P \u3c 0.05). The results of elevated frequency loading can provide insight into the long-term use of scaffolds suitable for bone tissue engineering. In this study, loading at an elevated frequency of 7.5 Hz increased the initial deformation (Y0) for both HA and TCP scaffolds. Such an observation is indicative of an increase in the modulus as the loading frequency increases. For both HA and TCP, 1 Hz, 2.5 Hz, and 7.5 Hz loading frequencies resulted in reduced K values indicative of a frequency dependence to loading rate. The decreased K values indicate an increased number of cycles prior to mechanical compromise,and hence improved mechanical resistance under fatigue loading. However, it is the significant increase in the K value noted at the 7.5-Hz loading frequency that is of interest, as it is indicative of increased energy transfer and a greater response of the HA and TCP scaffolds when compared with the other frequencies. Conclusions: The stiffening of the scaffolds at elevated frequencies may be of mechanical advantage when one considers the long-term physiological and cyclic loading and these devices are to sustain under clinical applications. Scaffold response should also be considered within the concepts of stress shielding and modulus matching to surrounding environments