1,315 research outputs found
Bridging the Experience-Complexity Gap with the Clinical Education Coordinator Role
https://scholarlycommons.libraryinfo.bhs.org/nurs_presentations2023/1002/thumbnail.jp
Bridging the Experience-Complexity Gap with the Clinical Education Coordinator Role
Holistic and Nursing Scholarship Symposium Event Postershttps://scholarlycommons.libraryinfo.bhs.org/nurs_presentations/1004/thumbnail.jp
Innovative Lesson Plans for Active Learning: Teaching Nursing Research and Evidence-Based Practice
Innovative Lessons Plans for Active Learning: Teaching Research and Evidence-Based Practice is a resource in research and evidence-based practice for active learning in the undergraduate nursing classroom. It is meant to supplement any nursing research text. Designed to provide educators with creative teaching ideas, this text includes a variety of lessons on nursing research topics. Topics include bias, measurement, sampling, theory and more. Lessons provide active learning for in-class, hybrid, and online formats. Each lesson includes objectives, overview, and detailed steps. As an open access resource, the text is continuously in-process. Designed to be independent of any published text, the book compliments any nursing research and evidence-based course. This text is also a suitable resource for introductory research in other disciplines.
Each chapter is an activity designed to supplement didactic andragogy. The activities develop creativity and facilitate engagement in the nursing research content. Through creative engagement, students access learning areas of the brain that otherwise remain unstimulated. Organized by the order in which they might be discussed in class, each chapter builds upon previous learning. In chapter two students are introduced by creating puppets to develop research questions and study ideas. Chapter three focuses specifically on generating problem and purpose statements. Culture shots in chapter five engages students in understanding theory generation, qualitative research and ethics in data collection. Chapters six and seven build upon and strengthen theory understanding through creating concepts and challenging assumptions. In chapter eight, biases and threats to validity are investigated through the use of parody. Sampling is addressed in chapters nine through eleven. Chapter twelve reinforces learning on measurement error. The last four chapters use creative games to help students pull it all together. Chapters thirteen and fourteen utilize existing free resources to enhance the learning experience. Chapters fifteen and sixteen allow students to work together to create understanding for themselves and other students.
We hope you enjoy the book as much as we enjoyed creating it. We would love to hear your comment and ideas for improvement. Please also view our video introduction at https://youtu.be/x9NDv2H_Cdg.https://scholarworks.gvsu.edu/books/1016/thumbnail.jp
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Organic synthesis reactions on-water at the organic-liquid water interface
Organic reactions that occur at the water interface for water-insoluble compounds, and reactions in water solution for water soluble compounds, has added a powerful dimension to prospects for organic synthesis under more beneficial economic and environmental conditions. Many organic molecules are partially soluble in water and reactions that appear as heterogeneous mixtures and suspensions may involve on-water and in-water reaction modes occurring simultaneously. The behavior of water molecules and organic molecules at this interface is discussed in the light of reported theoretical and experimental studies. The on-water catalytic effect, relative to neat reactions or organic solvents, ranges from factors of several hundred times to 1-2 times and it depends on the properties of reactant compounds. In some cases when on-water reactions produce quantitative yields of water-insoluble products they can reach ideal synthetic aspirations
DNP FINAL REPORT: THE IMPACT OF THE CARE COORDINATION MANAGEMENT TOOL ON CHILDREN WITH SPECIAL HEALTH CARE NEEDS
Children with Special Health Care Needs (CSHCN) population, account for 30% of spending or 280,172.38. Measurement of coordination activities were 41% parent education, 29% communication improvement, 21% investigation of services, 7% authorization, and 1% authorization review. By category, 29% of needs were related to utilization authorizations, 23% related to disease education, 16% referral for community resources, 18% education on Medicaid and 14% related to a behavioral health follow-up.
This project reveals that assigned case managers utilizing a standardized evidence-based tool can impact costs of care, parent satisfaction, and quality of life for the CSHCN patient
The Council of Europe's Approach towards Ageism
In this chapter, I examine the degree of interest in ageism among Council of
Europe members, and the degree of interest in its elimination through the Council
of Europe forum. I also examine the interpretation of the concept of ageism by various
Council of Europe institutions. Finally, I explore the Council’s willingness and
ability to eliminate or at least mitigate ageism effect
Experienced discrimination amongst European old citizens
This study analyses the experienced age discrimination of old European citizens and the factors related to this discrimination. Differences in experienced discrimination between old citizens of different European countries are explored. Data from the 2008 ESS survey are used. Old age is defined as being 62 years or older. The survey data come from 28 European countries and 14,364 old-age citizens. Their average age is 72 years. Factor analysis is used to construct the core variable ‘experienced discrimination’. The influence of the independent variables on experienced discrimination is analysed using linear regression analysis. About one-quarter of old European citizens sometimes or frequently experience discrimination because of their age. Gender, education, income and belonging to a minority are related to experienced age discrimination. Satisfaction with life and subjective health are strongly associated with experienced age discrimination, as is trust in other people and the seriousness of age discrimination in the country. Large, significant differences in experienced discrimination due to old age exist between European countries. A north-west versus south-east European gradient is found in experienced discrimination due to old age. The socio-cultural context is important in explaining experienced age discrimination in old European citizens. Old-age discrimination is experienced less frequently in countries with social security arrangements. Further research is needed to understand the variation in (old) age discrimination between European countries. Measures recommended include increasing public awareness about the value of ageing for communities and changing public attitudes towards the old in a positive way
Creative reminiscence as an early intervention for depression: results of a pilot project.
Reminiscence may help in resolving conflicts from the past and making up the balance of one’s life. Life-review may be further enhanced by the creative expression of memories in stories, poems or drawings. In this way people are encouraged to create and discover metaphors, images and stories that symbolically represent the subjective and inner meaning of their lives. In this article, a new intervention, which combines reminiscence and creative expression aimed at early treatment of depression, is described. A pilot project showed that the intervention Searching for the meaning in life may generate small-sized effects in reducing depression. Additionally, it appears to generate effects of medium size in enhancing mastery. Several possible ways to improve the effectiveness of the intervention are described
Multiplex Detection and SNP Genotyping in a Single Fluorescence Channel
Probe-based PCR is widely used for SNP (single nucleotide polymorphism) genotyping and pathogen nucleic acid detection due to its simplicity, sensitivity and cost-effectiveness. However, the multiplex capability of hydrolysis probe-based PCR is normally limited to one target (pathogen or allele) per fluorescence channel. Current fluorescence PCR machines typically have 4–6 channels. We present a strategy permitting the multiplex detection of multiple targets in a single detection channel. The technique is named Multiplex Probe Amplification (MPA). Polymorphisms of the CYP2C9 gene (cytochrome P450, family 2, subfamily C, polypeptide 9, CYP2C9*2) and human papillomavirus sequences HPV16, 18, 31, 52 and 59 were chosen as model targets for testing MPA. The allele status of the CYP2C9*2 determined by MPA was entirely concordant with the reference TaqMan® SNP Genotyping Assays. The four HPV strain sequences could be independently detected in a single fluorescence detection channel. The results validate the multiplex capacity, the simplicity and accuracy of MPA for SNP genotyping and multiplex detection using different probes labeled with the same fluorophore. The technique offers a new way to multiplex in a single detection channel of a closed-tube PCR
Sodium Phenylbutyrate Controls Neuroinflammatory and Antioxidant Activities and Protects Dopaminergic Neurons in Mouse Models of Parkinson’s Disease
Neuroinflammation and oxidative stress underlie the pathogenesis of various neurodegenerative disorders. Here we demonstrate that sodium phenylbutyrate (NaPB), an FDA-approved therapy for reducing plasma ammonia and glutamine in urea cycle disorders, can suppress both proinflammatory molecules and reactive oxygen species (ROS) in activated glial cells. Interestingly, NaPB also decreased the level of cholesterol but involved only intermediates, not the end product of cholesterol biosynthesis pathway for these functions. While inhibitors of both geranylgeranyl transferase (GGTI) and farnesyl transferase (FTI) inhibited the activation of NF-κB, inhibitor of GGTI, but not FTI, suppressed the production of ROS. Accordingly, a dominant-negative mutant of p21rac, but not p21ras, attenuated the production of ROS from activated microglia. Inhibition of both p21ras and p21rac activation by NaPB in microglial cells suggests that NaPB exerts anti-inflammatory and antioxidative effects via inhibition of these small G proteins. Consistently, we found activation of both p21ras and p21rac
in vivo in the substantia nigra of acute 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) mouse model of Parkinson’s disease. Oral administration of NaPB reduced nigral activation of p21ras and p21rac, protected nigral reduced glutathione, attenuated nigral activation of NF-κB, inhibited nigral expression of proinflammatory molecules, and suppressed nigral activation of glial cells. These findings paralleled dopaminergic neuronal protection, normalized striatal neurotransmitters, and improved motor functions in MPTP-intoxicated mice. Consistently, FTI and GGTI also protected nigrostriata in MPTP-intoxicated mice. Furthermore, NaPB also halted the disease progression in a chronic MPTP mouse model. These results identify novel mode of action of NaPB and suggest that NaPB may be of therapeutic benefit for neurodegenerative disorders
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