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Induction of dark-adaptive retinomotor movement (cell elongation) in teleost retinal cones by cyclic adenosine 3,5-monophosphate.
In the teleost retina, the photoreceptors and retinal pigment epithelium (RPE) undergo extensive movements (called retinomotor movements) in response to changes in light conditions and to an endogenous circadian rhythm. Photoreceptor movements serve to reposition the light-receptive outer segments and are effected by changes in inner segment length. Melanin granule movements within the RPE cells provide a movable melanin screen for rod outer segments. In the dark (night), cones elongate, rods contract, and pigment granules aggregate to the base of the RPE cell; in the light (day), these movements are reversed. We report here that treatments that elevate cytoplasmic cyclic adenosine 3,5-monophosphate (cAMP) provoke retinomotor movements characteristic of nighttime dark adaptation, even in bright light at midday. To illustrate this response, we present a quantitative description of the effects of cyclic nucleotides on cone length in the green sunfish, Lepomis cyanellus. Cone elongation is induced when light-adapted retinas are exposed to exogenous cAMP analogues accompanied by phosphodiesterase (PDE) inhibitors (either by intraocular injection or in retinal organ culture). Cone movements is not affected by cyclic GMP analogies. Dose-response studies indicate that the extent, but not the rate, of cone elongation is proportional to the concentration of exogenous cAMP and analogue presented. As has been reported for other species, we find that levels of cAMP are significantly higher in dark- than in light-adapted green sunfish retinas. On the basis of these observations, we suggest that cAMP plays a role in the light and circadian regulation of teleost cone length
GTD analysis of airborne antennas radiating in the presence of lossy dielectric layers
The patterns of monopole or aperture antennas mounted on a perfectly conducting convex surface radiating in the presence of a dielectric or metal plate are computed. The geometrical theory of diffraction is used to analyze the radiating system and extended here to include diffraction by flat dielectric slabs. Modified edge diffraction coefficients valid for wedges whose walls are lossy or lossless thin dielectric or perfectly conducting plates are developed. The width of the dielectric plates cannot exceed a quarter of a wavelength in free space, and the interior angle of the wedge is assumed to be close to 0 deg or 180 deg. Systematic methods for computing the individual components of the total high frequency field are discussed. The accuracy of the solutions is demonstrated by comparisons with measured results, where a 2 lambda by 4 lambda prolate spheroid is used as the convex surface. A jump or kink appears in the calculated pattern when higher order terms that are important are not included in the final solution. The most immediate application of the results presented here is in the modelling of structures such as aircraft which are composed of nonmetallic parts that play a significant role in the pattern
Simulation of an enhanced TCAS 2 system in operation
Described is a computer simulation of a Boeing 737 aircraft equipped with an enhanced Traffic and Collision Avoidance System (TCAS II). In particular, an algorithm is developed which permits the computer simulation of the tracking of a target airplane by a Boeing 373 which has a TCAS II array mounted on top of its fuselage. This algorithm has four main components: namely, the target path, the noise source, the alpha-beta filter, and threat detection. The implementation of each of these four components is described. Furthermore, the areas where the present algorithm needs to be improved are also mentioned
Dynamics of the nighttime thermosphere at Arecibo
Incoherent scatter radar observations of the nighttime F layer at Arecibo, Puerto Rico, are used to determine the O+ diffusion velocity at different altitudes. Further analysis allows evaluation of the neutral wind and the ion-drag force in the direction of the magnetic meridian. The local acceleration of the meridional neutral wind is also determined. The possibility of evaluating the viscous force using incoherent scatter radar data was also investigated. Preliminary results indicate that, at certain times and at altitudes above about 350 km, viscous drag may be a significant term in the neutral equation of motion. Combining these results allows height profiles of the meridional pressure gradient to be deduced. The pressure gradients thus derived is compared with that determined from measurements of the horizontal temperature gradient and that given by the MSIS model atmosphere
A study of a collision avoidance system mounted on a curved ground plane
Research conducted on a traffic advisory and collision avoidance system (TCAS 2) mounted on a curved ground plane is described. It is found that a curved finite ground plane can be used as a good simulation model for the fuselage of an aircraft but may not be good enough to model a whole aircraft due to the shadowing of the vertical stabilizer, wings, etc. The surface curvature of this curved disc significantly affects the monopulse characteristics in the azimuth plane but not as much in the elevation plane. These variations of the monopulse characteristics verify the need of a lookup table for the 64 azimuth beam positions. The best location of a TCAS 2 array on a Boeing 737 is to move it as far from the vertical stabilizer as possible
Modelling and performance analysis of four and eight element TCAS
This semi-annual report describes the work performed during the period September 1989 through March 1990. The first section presents a description of the effect of the engines of the Boeing 737-200 on the performance of a bottom mounted eight-element traffic alert and collision avoidance system (TCAS). The second section deals exclusively with a four element TCAS antenna. The model obtained to simulate the four element TCAS and new algorithms developed for studying its performance are described. The effect of location on its performance when mounted on top of a Boeing 737-200 operating at 1060 MHz is discussed. It was found that the four element TCAS generally does not perform as well as the eight element TCAS III
Simulation of the enhanced traffic alert and collision avoidance system (TCAS 2)
The OSU aircraft code is used to analyze and simulate the TCAS 2 circular array which is mounted on the fuselage of a Boeing 737 aircraft. It is shown that the sum and difference patterns radiated by the circular array are distorted by the various structures of the aircraft, i.e., wings, tail, etc. Furthermore, monopulse curves are calculated and plotted for several beam positions and THETA angles. As expected, the worst cases of distortion occur when the beams are pointed toward the tail of the aircraft
Observations of neutral circulation at mid-latitudes during the Equinox Transition Study
Measurements of ion drift velocity made by the Millstone Hill incoherent scatter radar have been used to calculate the meridional neutral wind velocity during the Sept. 17 to 24, 1984 period. Strong daytime southward neutral surges were observed during the magnetically disturbed days of September 19 and 23, in contrast to the small daytime winds obtained as expected during the magnetically quiet days. The surge on September 19 was also seen at Arecibo. In addition, two approaches have been used to calculate the meridional wind component from the radar-derived height of the F-layer electron density peak. Results confirm the wind surge, particularly when the strong electric fields measured during the disturbed days are included in the calculations. The two approaches for the F-layer peak wind calculations are applied to the radar-derived electron density peak height as a function of latitude to study the variation of the southward daytime surges with latitude
Computational Fluid Dynamics in Small Airway Models of the Human Lung
The promise of gene replacement therapy for cystic fibrosis, the administration of drugs via inhalation therapy, and die deposition location of man-made airborne particulates all involve a more complete understanding of the fluid dynamics in the human lung. Flow in the larger airways may be measured through life-sized models directly, but the airways in the peripheral lung are too small and the flows are too complex to be studied in this manner. Computational models can be developed which will accurately represent both the geometric nature of the central airways and the fluid dynamics with in them. Two-dimensional and three-dimensional models of central lung airway bifurcations were developed based on morphometry. These models were used as the spatial basis upon which the differential equations that describe incompressible flow, the Navier Stokes equations, are solved. Flow solutions have been computed at Reynolds numbers from 1000 down to 100. Solutions for single and double bifurcations agree with the experimental data for flow in a branching tube. These studies are being extended to multiple bifurcations in three dimensions
On uniformization of Burnside's curve
Main objects of uniformization of the curve are studied: its
Burnside's parametrization, corresponding Schwarz's equation, and accessory
parameters. As a result we obtain the first examples of solvable Fuchsian
equations on torus and exhibit number-theoretic integer -series for
uniformizing functions, relevant modular forms, and analytic series for
holomorphic Abelian integrals. A conjecture of Whittaker for hyperelliptic
curves and its hypergeometric reducibility are discussed. We also consider the
conversion between Burnside's and Whittaker's uniformizations.Comment: Final version. LaTeX, 23 pages, 1 figure. The handbook for elliptic
functions has been moved to arXiv:0808.348
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