322 research outputs found
Multiscale correlative tomography: an investigation of creep cavitation in 316 stainless steel
Creep cavitation in an ex-service nuclear steam header Type 316 stainless steel sample is investigated through a multiscale tomography workflow spanning eight orders of magnitude, combining X-ray computed tomography (CT), plasma focused ion beam (FIB) scanning electron microscope (SEM) imaging and scanning transmission electron microscope (STEM) tomography. Guided by microscale X-ray CT, nanoscale X-ray CT is used to investigate the size and morphology of cavities at a triple point of grain boundaries. In order to understand the factors affecting the extent of cavitation, the orientation and crystallographic misorientation of each boundary is characterised using electron backscatter diffraction (EBSD). Additionally, in order to better understand boundary phase growth, the chemistry of a single boundary and its associated secondary phase precipitates is probed through STEM energy dispersive X-ray (EDX) tomography. The difference in cavitation of the three grain boundaries investigated suggests that the orientation of grain boundaries with respect to the direction of principal stress is important in the promotion of cavity formation
The Making of a Self-Neglect Severity Scale
Research in elder self-neglect has lagged behind that of other forms of mistreatment, despite the fact that self-neglect is the most common allegation reported to Adult Protective Service agencies throughout the US. The lack of a gold-standard to measure self-neglect has hampered efforts to study this phenomenon. Researchers designed the Self-neglect Severity Scale (SSS) based on interviews with Adult Protective Service workers and a national expert panel. The SSS is based on observation and interview and is administered in the home to include an environmental assessment. It was piloted, extensively field tested and then revised. The CREST SSS was developed using survey data and consultation with experts in the field. This instrument utilizes observer ratings, interview responses, and assesses subjects physical and environmental domains. It also assesses functional status as it relates to health and safety issues. After field and pilot testing the SSS was finalized and is currently undergoing reliability and validity testing. The CREST SSS was developed as a state scale to provide a common language for describing cases of self-neglect. It is the first self-neglect severity scale available to researchers. If found to be both reliable and valid it can be used in future intervention studies
Gamma Ray Large Area Space Telescope (GLAST) Balloon Flight Data Handling Overview
The GLAST Balloon Flight Engineering Model (BFEM) represents one of 16 towers
that constitute the Large Area Telescope (LAT), a high-energy (>20 MeV)
gamma-ray pair-production telescope being built by an international partnership
of astrophysicists and particle physicists for a satellite launch in 2006. The
prototype tower consists of a Pb/Si pair-conversion tracker (TKR), a CsI
hodoscopic calorimeter (CAL), an anti-coincidence detector (ACD) and an
autonomous data acquisition system (DAQ). The self-triggering capabilities and
performance of the detector elements have been previously characterized using
positron, photon and hadron beams. External target scintillators were placed
above the instrument to act as sources of hadronic showers. This paper provides
a comprehensive description of the BFEM data-reduction process, from receipt of
the flight data from telemetry through event reconstruction and background
rejection cuts. The goals of the ground analysis presented here are to verify
the functioning of the instrument and to validate the reconstruction software
and the background-rejection scheme.Comment: 5 pages, 4 figures, to be published in IEEE Transacations on Nuclear
Science, August 200
Recommended from our members
Does the Social Capital in Networks of ‘‘Fish and Fire’’ Scientists and Managers Suggest Learning?
Patterns of social interaction influence how knowledge is generated, communicated,
and applied. Theories of social capital and organizational learning suggest that
interactions within disciplinary or functional groups foster communication of
knowledge, whereas interactions across groups foster generation of new knowledge.
We used social network analysis to examine patterns of social interaction reported
in survey data from scientists and managers who work on fish and fire issues.
We found that few fish and fire scientists and managers interact with one another,
suggesting low bridging social capital and thus, limited opportunity for generation
of new knowledge. We also found that although interaction occurs among
scientists—suggesting modest bonding social capital—few managers interact
with other managers, indicating limited opportunity for communication of scientific
knowledge for the purposes of application. We discuss constraints and opportunities
for organizational learning evident in these patterns of social interaction among fish
and fire scientists and managers.Keywords: riparian and aquatic issues, natural resource agencies, organizational learning, social network analysis, wildland fire, social capita
Characterizing the Optical Variability of Bright Blazars: Variability-based Selection of Fermi Active Galactic Nuclei
We investigate the use of optical photometric variability to select and identify blazars in large-scale time-domain
surveys, in part to aid in the identification of blazar counterparts to the ∼30% of γ -ray sources in the Fermi 2FGL
catalog still lacking reliable associations. Using data from the optical LINEAR asteroid survey, we characterize the
optical variability of blazars by fitting a damped random walk model to individual light curves with two main model
parameters, the characteristic timescales of variability τ , and driving amplitudes on short timescales σ . Imposing
cuts on minimum τ and σ allows for blazar selection with high efficiency E and completeness C. To test the
efficacy of this approach, we apply this method to optically variable LINEAR objects that fall within the several arcminute error ellipses of γ -ray sources in the Fermi 2FGL catalog. Despite the extreme stellar contamination at the shallow depth of the LINEAR survey, we are able to recover previously associated optical counterparts to Fermi active galactic nuclei with E ≥ 88% and C = 88% in Fermi 95% confidence error ellipses having semimajor axis r < 8'. We find that the suggested radio counterpart to Fermi source 2FGL J1649.6+5238 has optical variability consistent with other γ -ray blazars and is likely to be the γ -ray source. Our results suggest that the variability of the non-thermal jet emission in blazars is stochastic in nature, with unique variability properties due to the effects of relativistic beaming. After correcting for beaming, we estimate that the characteristic timescale of blazar variability is ∼3 years in the rest frame of the jet, in contrast with the ∼320 day disk flux timescale observed in quasars. The variability-based selection method presented will be useful for blazar identification in time-domain optical surveys and is also a probe of jet physics
Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks, 1990–2015:a systematic analysis for the Global Burden of Disease Study 2015
Published by Elsevier Ltd. This is an Open Access article under the CC BY license.Background
The Global Burden of Diseases, Injuries, and Risk Factors Study 2015 provides an up-to-date synthesis of the evidence for risk factor exposure and the attributable burden of disease. By providing national and subnational assessments spanning the past 25 years, this study can inform debates on the importance of addressing risks in context.
Methods
We used the comparative risk assessment framework developed for previous iterations of the Global Burden of Disease Study to estimate attributable deaths, disability-adjusted life-years (DALYs), and trends in exposure by age group, sex, year, and geography for 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks from 1990 to 2015. This study included 388 risk-outcome pairs that met World Cancer Research Fund-defined criteria for convincing or probable evidence. We extracted relative risk and exposure estimates from randomised controlled trials, cohorts, pooled cohorts, household surveys, census data, satellite data, and other sources. We used statistical models to pool data, adjust for bias, and incorporate covariates. We developed a metric that allows comparisons of exposure across risk factors—the summary exposure value. Using the counterfactual scenario of theoretical minimum risk level, we estimated the portion of deaths and DALYs that could be attributed to a given risk. We decomposed trends in attributable burden into contributions from population growth, population age structure, risk exposure, and risk-deleted cause-specific DALY rates. We characterised risk exposure in relation to a Socio-demographic Index (SDI).
Findings
Between 1990 and 2015, global exposure to unsafe sanitation, household air pollution, childhood underweight, childhood stunting, and smoking each decreased by more than 25%. Global exposure for several occupational risks, high body-mass index (BMI), and drug use increased by more than 25% over the same period. All risks jointly evaluated in 2015 accounted for 57·8% (95% CI 56·6–58·8) of global deaths and 41·2% (39·8–42·8) of DALYs. In 2015, the ten largest contributors to global DALYs among Level 3 risks were high systolic blood pressure (211·8 million [192·7 million to 231·1 million] global DALYs), smoking (148·6 million [134·2 million to 163·1 million]), high fasting plasma glucose (143·1 million [125·1 million to 163·5 million]), high BMI (120·1 million [83·8 million to 158·4 million]), childhood undernutrition (113·3 million [103·9 million to 123·4 million]), ambient particulate matter (103·1 million [90·8 million to 115·1 million]), high total cholesterol (88·7 million [74·6 million to 105·7 million]), household air pollution (85·6 million [66·7 million to 106·1 million]), alcohol use (85·0 million [77·2 million to 93·0 million]), and diets high in sodium (83·0 million [49·3 million to 127·5 million]). From 1990 to 2015, attributable DALYs declined for micronutrient deficiencies, childhood undernutrition, unsafe sanitation and water, and household air pollution; reductions in risk-deleted DALY rates rather than reductions in exposure drove these declines. Rising exposure contributed to notable increases in attributable DALYs from high BMI, high fasting plasma glucose, occupational carcinogens, and drug use. Environmental risks and childhood undernutrition declined steadily with SDI; low physical activity, high BMI, and high fasting plasma glucose increased with SDI. In 119 countries, metabolic risks, such as high BMI and fasting plasma glucose, contributed the most attributable DALYs in 2015. Regionally, smoking still ranked among the leading five risk factors for attributable DALYs in 109 countries; childhood underweight and unsafe sex remained primary drivers of early death and disability in much of sub-Saharan Africa.
Interpretation
Declines in some key environmental risks have contributed to declines in critical infectious diseases. Some risks appear to be invariant to SDI. Increasing risks, including high BMI, high fasting plasma glucose, drug use, and some occupational exposures, contribute to rising burden from some conditions, but also provide opportunities for intervention. Some highly preventable risks, such as smoking, remain major causes of attributable DALYs, even as exposure is declining. Public policy makers need to pay attention to the risks that are increasingly major contributors to global burden
- …