Natural Products in Organic Synthesis

A resume of four lectures presented by the author during a one month visit to BIOTROP in 1995. The seminars were held at the University of Indonesia at Depok, the Technical Institute in Bandung, the Bogor Agricultural Institute and at BIOTROP, Bogor. The talks were grouped under the general title "The Use of Natural Products in Organic Synthesis"

Wilson Line Picture of Levin-Wen Partition Functions

Levin and Wen [Phys. Rev. B 71, 045110 (2005)] have recently given a lattice Hamiltonian description of doubled Chern-Simons theories. We relate the partition function of these theories to an expectation of Wilson loops that form a link in 2+1 dimensional spacetime known in the mathematical literature as Chain-Mail. This geometric construction gives physical interpretation of the Levin-Wen Hilbert space and Hamiltonian, its topological invariance, exactness under coarse-graining, and how two opposite chirality sectors of the doubled theory arise.Comment: Final published version; Appendix adde

Deuteron and proton NMR study of D₂, p-dichlorobenzene and 1,3,5-trichlorobenzene in bimesogenic liquid crystals with two nematic phases

The solutes dideuterium, 1,3,5-trichlorobenzene and p-dichlorobenzene (pdcb) are co-dissolved in a 61/39 wt% mixture of CBC9CB/5CB, a bimesogenic liquid crystal with two nematic phases. NMR spectra are collected for each solute. The local electric field gradient (FZZ) is obtained from the dideuterium spectrum. A double Maier-Saupe potential (MSMS) is used to rationalize the order parameters of pdcb. The liquid-crystal fields G₁ and G₂ are taken to be due to size and shape interactions and interactions between the solute molecular quadrupole and the mean FZZ of the medium. The FZZ’s obtained from D₂ and G₂ (from pdcb) are compared and discussed

NMR study of a bimesogenic liquid crystal with two nematic phases

Recent interest in bimesogenic liquid crystals showing two nematic phases has led us to investigate the nematic mean-field interactions in these nematic phases by using rigid solutes as probes. The nematic potential that is modelled by two independent Maier-Saupe terms is successful in fitting the observed dipolar couplings (order parameters) of para-, meta- and ortho-dichlorobenzene solutes in both the nematic phases of 39 wt% of 4-n-pentyl-4′-cyanobiphenyl (5CB) in α,ω-bis(4-4′-cyanobiphenyl)nonane (CB_C9_CB) to better than the 5% level. The derived liquid-crystal potential parameters G₁ and G₂ for each solute in the N and Ntb phases will be discussed. The most interesting observation is that G1 (associated with size and shape interactions) is almost constant in the Ntb phase, whereas G₂ (associated with longer-range electrostatic interactions) has large variation, even changing sign

Legislative strengthening meets party support in international assistance: a closer relationship?

Recent reports recommend that international efforts to help strengthen legislatures in emerging democracies should work more closely with support for building stronger political parties and competitive party systems. This article locates the recommendations within international assistance more generally and reviews the arguments. It explores problems that must be addressed if the recommendations are to be implemented effectively. The article argues that an alternative, issue-based approach to strengthening legislatures and closer links with civil society could gain more traction. However, that is directed more centrally at promoting good governance for the purpose of furthering development than at democratisation goals sought by party aid and legislative strengtheners in the democracy assistance industry

Chaos in a Relativistic 3-body Self-Gravitating System

We consider the 3-body problem in relativistic lineal gravity and obtain an exact expression for its Hamiltonian and equations of motion. While general-relativistic effects yield more tightly-bound orbits of higher frequency compared to their non-relativistic counterparts, as energy increases we find in the equal-mass case no evidence for either global chaos or a breakdown from regular to chaotic motion, despite the high degree of non-linearity in the system. We find numerical evidence for a countably infinite class of non-chaotic orbits, yielding a fractal structure in the outer regions of the Poincare plot.Comment: 9 pages, LaTex, 3 figures, final version to appear in Phys. Rev. Let

X 1908+075: An X-ray Binary with a 4.4 day Period

X 1908+075 is an optically unidentified and highly absorbed X-ray source that appears in early surveys such as Uhuru, OSO-7, Ariel V, HEAO-1, and the EXOSAT Galactic Plane Survey. These surveys measured a source intensity in the range of 2-12 mCrab at 2-10 keV, and the position was localized to ~ 0.5 degrees. We use the Rossi X-ray Timing Explorer (RXTE) All Sky Monitor (ASM) to confirm our expectation that a particular Einstein IPC detection (1E 1908.4+0730) provides the correct position for X 1908+075. The analysis of the coded mask shadows from the ASM for the position of 1E 1908.4+0730 yields a persistent intensity ~ 8 mCrab (1.5-12 keV) over a 3 year interval beginning in 1996 February. Furthermore, we detect a period of 4.400 +- 0.001 days with a false alarm probability < 1.0e-7 . The folded light curve is roughly sinusoidal, with an amplitude that is 22 % of the mean flux. The X-ray period may be attributed to the scattering and absorption of X-rays through a stellar wind combined with the orbital motion in a binary system. We suggest that X 1908+075 is an X-ray binary with a high mass companion star.Comment: 6 pages, two-column,"emulateapj" style, submitted to Ap

Linear Multivariable Regression Models for Prediction of Eddy Dissipation Rate from Available Meteorological Data

Linear multivariable regression models for predicting day and night Eddy Dissipation Rate (EDR) from available meteorological data sources are defined and validated. Model definition is based on a combination of 1997-2000 Dallas/Fort Worth (DFW) data sources, EDR from Aircraft Vortex Spacing System (AVOSS) deployment data, and regression variables primarily from corresponding Automated Surface Observation System (ASOS) data. Model validation is accomplished through EDR predictions on a similar combination of 1994-1995 Memphis (MEM) AVOSS and ASOS data. Model forms include an intercept plus a single term of fixed optimal power for each of these regression variables; 30-minute forward averaged mean and variance of near-surface wind speed and temperature, variance of wind direction, and a discrete cloud cover metric. Distinct day and night models, regressing on EDR and the natural log of EDR respectively, yield best performance and avoid model discontinuity over day/night data boundaries

The incidence of Gorlin syndrome in 173 consecutive cases of medulloblastoma.

We have investigated the incidence of Gorlin syndrome (GS) in patients with the childhood brain tumour, medulloblastoma. One hundred and seventy-three consecutive cases of medulloblastoma in the North-West Regional Health Authority between 1954 and 1989 (Manchester Regional Health Board before 1974) were studied. After review of case notes, X-rays and health surveys only 2/173 cases had evidence supporting a diagnosis of GS. A further case at 50% risk of GS died of a brain tumour aged 4 years. The incidence of GS in medulloblastoma is, therefore, probably between 1-2%. A population based study of GS in the region started in 1983 was used to assess the incidence of medulloblastoma in GS, which was found to be between 3-5%. This figure is lower than previous estimates, but this is the first population based study undertaken. In view of the early age of onset in GS (mean 2 years) children presenting with medulloblastoma, especially under 5 years, should be examined for signs of the syndrome. Those at high risk of developing multiple invasive basal cell carcinomata will then be identified

Observation of anomalous Meissner screening in Cu/Nb and Cu/Nb/Co thin films

We have observed the spatial distribution of magnetic flux in Nb, Cu/Nb and Cu/Nb/Co thin films using muon-spin rotation. In an isolated 50 nm thick Nb film we find a weak flux expulsion (Meissner effect) which becomes significantly enhanced when adding an adjacent 40 nm layer of Cu. The added Cu layer exhibits a Meissner effect (due to induced superconducting pairs) and is at least as effective as the Nb to expel flux. These results are confirmed by theoretical calculations using the quasiclassical Green’s function formalism. An unexpected further significant enhancement of the flux expulsion is observed when adding a thin (2.4 nm) ferromagnetic Co layer to the bottom side of the Nb. This observed cooperation between superconductivity and ferromagnetism, by an unknown mechanism, forms a key ingredient for developing superconducting spintronics