Anthocyanins do not influence long-chain n-3 fatty acid status:Studies in cells, rodents and humans

Increased tissue status of the long-chain n-3 polyunsaturated fatty acids (LC n-3 PUFA), eicosapentaenoic (EPA) and docosahexaenoic acid (DHA) is associated with cardiovascular and cognitive benefits. Limited epidemiological and animal data suggest that flavonoids, and specifically anthocyanins, may increase EPA and DHA levels, potentially by increasing their synthesis from the shorter-chain n-3 PUFA, α-linolenic acid. Using complimentary cell, rodent and human studies we investigated the impact of anthocyanins and anthocyanin-rich foods/extracts on plasma and tissue EPA and DHA levels and on the expression of fatty acid desaturase 2 (FADS2), which represents the rate limiting enzymes in EPA and DHA synthesis. In experiment 1, rats were fed a standard diet containing either palm oil or rapeseed oil supplemented with pure anthocyanins for 8 weeks. Retrospective fatty acid analysis was conducted on plasma samples collected from a human randomized controlled trial where participants consumed an elderberry extract for 12 weeks (experiment 2). HepG2 cells were cultured with α-linolenic acid with or without select anthocyanins and their in vivo metabolites for 24 h and 48 h (experiment 3). The fatty acid composition of the cell membranes, plasma and liver tissues were analyzed by gas chromatography. Anthocyanins and anthocyanin-rich food intake had no significant impact on EPA or DHA status or FADS2 gene expression in any model system. These data indicate little impact of dietary anthocyanins on n-3 PUFA distribution and suggest that the increasingly recognized benefits of anthocyanins are unlikely to be the result of a beneficial impact on tissue fatty acid status

Cataclysmic Variables in the First Year of the Zwicky Transient Facility

Using selection criteria based on amplitude, time, and color, we have identified 329 objects as known or candidate cataclysmic variables (CVs) during the first year of testing and operation of the Zwicky Transient Facility. Of these, 90 are previously confirmed CVs, 218 are strong candidates based on the shape and color of their light curves obtained during 3–562 days of observation, and the remaining 21 are possible CVs but with too few data points to be listed as good candidates. Almost half of the strong candidates are within 10 deg of the galactic plane, in contrast to most other large surveys that have avoided crowded fields. The available Gaia parallaxes are consistent with sampling the low mass transfer CVs, as predicted by population models. Our follow-up spectra have confirmed Balmer/helium emission lines in 27 objects, with four showing high-excitation He ii emission, including candidates for an AM CVn, a polar, and an intermediate polar. Our results demonstrate that a complete survey of the Galactic plane is needed to accomplish an accurate determination of the number of CVs existing in the Milky Way

A new class of large-amplitude radial-mode hot subdwarf pulsators

Using high-cadence observations from the Zwicky Transient Facility at low Galactic latitudes, we have discovered a new class of pulsating, hot compact stars. We have found four candidates, exhibiting blue colors (g − r ≤ −0.1 mag), pulsation amplitudes of >5%, and pulsation periods of 200–475 s. Fourier transforms of the light curves show only one dominant frequency. Phase-resolved spectroscopy for three objects reveals significant radial velocity, T eff, and log(g) variations over the pulsation cycle, which are consistent with large-amplitude radial oscillations. The mean T eff and log(g) for these stars are consistent with hot subdwarf B (sdB) effective temperatures and surface gravities. We calculate evolutionary tracks using MESA and adiabatic pulsations using GYRE for low-mass, helium-core pre-white dwarfs (pre-WDs) and low-mass helium-burning stars. Comparison of low-order radial oscillation mode periods with the observed pulsation periods show better agreement with the pre-WD models. Therefore, we suggest that these new pulsators and blue large-amplitude pulsators (BLAPs) could be members of the same class of pulsators, composed of young ≈0.25–0.35 M ⊙ helium-core pre-WDs.Published versio

A design method for prismatic prestressed continuous box girder bridges

Prestressed concrete is one of the most difficult building materials to design due to many reasons such as number of different solutions available for the same problem and the time dependent changes that take place. When used for continuous box girder bridges, there are added problems associated with secondary moments. In this paper, a straight forward design method has been presented that localises the iterations involved in the design process as much as possible so that the calculations involved can be minimised. The guidelines to determine the cross sectional dimensions has also been discussed. A complete design example has been presented for a three span continuous bridge. A simple method for modelling a box girder as a grillage of beams also has been presented

Measurements of Aperture Averaging on Bit-Error-Rate

We report on measurements made at the Shuttle Landing Facility (SLF) runway at Kennedy Space Center of receiver aperture averaging effects on a propagating optical Gaussian beam wave over a propagation path of 1,000 in. A commercially available instrument with both transmit and receive apertures was used to transmit a modulated laser beam operating at 1550 nm through a transmit aperture of 2.54 cm. An identical model of the same instrument was used as a receiver with a single aperture that was varied in size up to 20 cm to measure the effect of receiver aperture averaging on Bit Error Rate. Simultaneous measurements were also made with a scintillometer instrument and local weather station instruments to characterize atmospheric conditions along the propagation path during the experiments

An 8.8 minute orbital period eclipsing detached double white dwarf binary

We report the discovery of ZTF J2243+5242, an eclipsing double white dwarf binary with an orbital period of just $8.8$ minutes, the second known eclipsing binary with an orbital period less than ten minutes. The system likely consists of two low-mass white dwarfs, and will merge in approximately 400,000 years to form either an isolated hot subdwarf or an R Coronae Borealis star. Like its $6.91\, \rm min$ counterpart, ZTF J1539+5027, ZTF J2243+5242 will be among the strongest gravitational wave sources detectable by the space-based gravitational-wave detector The Laser Space Interferometer Antenna (LISA) because its gravitational-wave frequency falls near the peak of LISA's sensitivity. Based on its estimated distance of $d=2120^{+131}_{-115}\,\rm pc$, LISA should detect the source within its first few months of operation, and should achieve a signal-to-noise ratio of $87\pm5$ after four years. We find component masses of $M_A= 0.349^{+0.093}_{-0.074}\,M_\odot$ and $M_B=0.384^{+0.114}_{-0.074}\,M_\odot$, radii of $R_A=0.0308^{+0.0026}_{-0.0025}\,R_\odot$ and $R_B = 0.0291^{+0.0032}_{-0.0024}\,R_\odot$, and effective temperatures of $T_A=22200^{+1800}_{-1600}\,\rm K$ and $T_B=16200^{+1200}_{-1000}\,\rm K$. We determined all of these properties, and the distance to this system, using only photometric measurements, demonstrating a feasible way to estimate parameters for the large population of optically faint ($r>21 \, m_{\rm AB}$) gravitational-wave sources which the Vera Rubin Observatory (VRO) and LISA should identify.Comment: 12 pages, 7 figures, 3 tables, submitte

Orbital Decay in a 20 Minute Orbital Period Detached Binary with a Hydrogen-poor Low-mass White Dwarf

We report the discovery of a detached double white dwarf binary with an orbital period of ≈20.6 minutes, PTF J053332.05+020911.6. The visible object in this binary, PTF J0533+0209B, is a ≈0.17 M⊙ mass white dwarf with a helium-dominated atmosphere containing traces of hydrogen. This object exhibits ellipsoidal variations due to tidal deformation, and is the visible component in a single-lined spectroscopic binary with a velocity semi-amplitude of K_B = 618.7 ± 6.9 km s⁻¹. We have detected significant orbital decay due to the emission of gravitational radiation, and we expect that the Laser Interferometer Space Antenna (LISA) will detect this system with a signal to noise of 8.4^(+4.2)_(-3.0) after four years of operation. Because this system already has a well-determined orbital period, radial velocity semi-amplitude, temperature, atmospheric composition, surface gravity, and orbital decay rate, a LISA signal will help fully constrain the properties of this system by providing a direct measurement of its inclination. Thus, this binary demonstrates the synergy between electromagnetic and gravitational radiation for constraining the physical properties of an astrophysical object

A red giant orbiting a black hole

We report spectroscopic and photometric follow-up of a dormant black hole (BH) candidate from Gaia DR3. We show that the system, which we call Gaia BH2, contains a $\sim 1M_{\odot}$ red giant and a dark companion with mass $M_2 = 8.9\pm 0.3\,M_{\odot}$ that is very likely a BH. The orbital period, $P_{\rm orb} = 1277$ days, is much longer than that of any previously studied BH binary. Our radial velocity (RV) follow-up over a 6-month period spans most of the orbit's dynamic range in RV and is in excellent agreement with predictions of the Gaia solution. UV imaging and high-resolution optical spectra rule out all plausible luminous companions that could explain the orbit. The star is a bright ($G=12.3$), slightly metal-poor ($\rm [Fe/H]=-0.22$) low-luminosity giant ($T_{\rm eff}=4600\,\rm K$; $R = 7.9\,R_{\odot}$; $\log\left[g/\left({\rm cm\,s^{-2}}\right)\right] = 2.6$). The binary's orbit is moderately eccentric ($e=0.52$). The giant is strongly enhanced in $\alpha-$elements, with $\rm [\alpha/Fe] = +0.26$, but the system's Galactocentric orbit is typical of the thin disk. We obtained X-ray and radio nondetections of the source near periastron, which support BH accretion models in which the net accretion rate at the horizon is much lower than the Bondi-Hoyle-Lyttleton rate. At a distance of 1.16 kpc, Gaia BH2 is the second-nearest known BH, after Gaia BH1. Its orbit -- like that of Gaia BH1 -- seems too wide to have formed through common envelope evolution. Gaia BH1 and BH2 have orbital periods at opposite edges of the Gaia DR3 sensitivity curve, perhaps hinting at a bimodal intrinsic period distribution for wide BH binaries. Dormant BH binaries like Gaia BH1 and Gaia BH2 likely significantly outnumber their close, X-ray bright cousins, but their formation pathways remain uncertain.Comment: 22 pages, 15 figures. Submitted to MNRA