1,110 research outputs found

    The effect of gluon condensate on holographic heavy quark potential

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    The gluon condensate is very sensitive to the QCD deconfinement transition since its value changes drastically with the deconfinement transition. We calculate the gluon condensate dependence of the heavy quark potential in AdS/CFT to study how the property of the heavy quarkonium is affected by a relic of the deconfinement transition. We observe that the heavy quark potential becomes deeper as the value of the gluon condensate decreases. We interpret this as a dropping of the heavy quarkonium mass just above the deconfinement transition, which is similar to the results obtained from QCD sum rule and from a bottom-up AdS/QCD model.Comment: 16 pages, 6 figures, typos corrected, references adde

    What triggers firms to appoint outside directors beyond the legal minimum requirement?

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    Background: Although previous studies provide important insights on how firms respond to institutional pressure, they fail to acknowledge the salience of globalisation that results in institutional pressures diffusing across countries. Objectives: Drawing on a selective adaptation model, this article examines whether firms comply with reforms to board structures beyond the minimum legal requirement. Method: It investigates the determinants of appointing outside directors beyond the minimum legal requirement by analysing the relationship between four main variables and minimum compliance. Results: Using a sample of Korean listed firms during 2002–2014, this study found that the salient organisational conditions (firm complexity and firm performance) and key organisational actors (controlling shareholders and foreign investors) determine the extent to which firms appoint outside directors on their boards. Conclusion: This study contributes to the strategy literature that examines organisational response to institutional pressure, furthering the understanding of why there is heterogeneity in firm decisions even from firms in the same institutional environment that face similar institutional pressures. Moreover, it makes a contribution to corporate governance literature, in particular to the adoption of governance mechanisms that originate from foreign models

    Treatment for the Lumbosacral Soft Tissue Defect after Spine Surgery

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    The lumbosacral area is one of the most frequently operated spine regions because of the prevalence of disease in that area. Although a lumbosacral soft tissue defect after surgery due to inflammation and other causes is rare, such soft tissue defects are difficult to treat. Therefore, suitable methods for treating lumbosacral soft tissue defects are necessary. Therefore, this study introduces a case-treated with a transverse lumbosacral rotational flap

    A New p53 Target Gene, RKIP, Is Essential for DNA Damage-Induced Cellular Senescence and Suppression of ERK Activation

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    Abstractp53, a strong tumor suppressor protein, is known to be involved in cellular senescence, particularly premature cellular senescence. Oncogenic stresses, such as Ras activation, can initiate p53-mediated senescence, whereas activation of the Ras-mitogen-activated protein kinase (MAPK) pathway can promote cell proliferation. These conflicting facts imply that there is a regulatory mechanism for balancing p53 and Ras-MAPK signaling. To address this, we evaluated the effects of p53 on the extracellular signal-regulated kinase (ERK) activation and found that p53 could suppress ERK activation through de novo synthesis. Through several molecular biologic analyses, we found that RKIP, an inhibitor of Raf kinase, is responsible for p53-mediated ERK suppression and senescence. Overexpression of RKIP can induce cellular senescence in several types of cell lines, including p53-deficient cells, whereas the elimination of RKIP by siRNA or forced expression of ERK blocks p53-mediated cellular senescence. These results suggested that RKIP is an essential protein for cellular senescence. Moreover, modification of the p53 serine 46 residue was critical for RKIP induction and ERK suppression as well as cellular senescence. These results indicated that RKIP is a novel p53 target gene that is responsible for p53-mediated cellular senescence and tumor suppressor protein expression

    Characteristics of Mechanical Ventilation Employed in Intensive Care Units: A Multicenter Survey of Hospitals

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    A 1D point-prevalence study was performed to describe the characteristics of conventional mechanical ventilation in intensive care units (ICUs). In addition, a survey was conducted to determine the characteristics of ICUs. A prospective, multicenter study was performed in ICUs at 24 university hospitals. The study population consisted of 223 patients who were receiving mechanical ventilation or had been weaned off mechanical ventilation within the past 24 hr. Common indications for the initiation of mechanical ventilation included acute respiratory failure (66%), acute exacerbation of chronic respiratory failure (15%) (including tuberculosis-destroyed lung [5%]), coma (13%), and neuromuscular disorders (6%). Mechanical ventilation was delivered via an endotracheal tube in 68% of the patients, tracheostomy in 28% and facial mask with noninvasive ventilation (NIV) in 4%. NIV was used in 2 centers. In patients who had undergone tracheostomy, the procedure had been performed 16.9±8.1 days after intubation. Intensivists treated 29% of the patients. A need for additional educational programs regarding clinical practice in the ICU was expressed by 62% of the staff and 42% of the nurses. Tuberculosis-destroyed lung is a common indication for mechanical ventilation in acute exacerbation of chronic respiratory failure, and noninvasive ventilation was used in a limited number of ICUs

    Power Management of Nanogrid Cluster with P2P Electricity Trading Based on Future Trends of Load Demand and PV Power Production

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    This paper presents the power management of the nanogrid clusters assisted by a novel peer-to-peer(P2P) electricity trading. In our work, unbalance of power consumption among clusters is mitigated by the proposed P2P trading method. For power management of individual clusters, multi-objective optimization simultaneously minimizing total power consumption, portion of grid power consumption, and total delay incurred by scheduling is attempted. A renewable power source photovoltaic(PV) system is adopted for each cluster as a secondary source. The temporal surplus of self-supply PV power of a cluster can be sold through P2P trading to another cluster (s) experiencing temporal power shortage. The cluster in temporal shortage of electric power buys the PV power to reduce peak load and total delay. In P2P trading, a cooperative game model is used for buyers and sellers to maximize their welfare. To increase P2P trading efficiency, future trends of load demand and PV power production are considered for power management of each cluster to resolve instantaneous unbalance between load demand and PV power production. To this end, a gated recurrent unit network is used to forecast future load demand and future PV power production. Simulations verify the effectiveness of the proposed P2P trading for nanogrid clusters.Comment: This article is submitted for publication in Sustainable Cities and Societ

    Indoor formaldehyde removal over CMK-3

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    The removal of formaldehyde at low concentrations is important in indoor air pollution research. In this study, mesoporous carbon with a large specific surface area was used for the adsorption of low-concentration indoor formaldehyde. A mesoporous carbon material, CMK-3, was synthesized using the nano-replication method. SBA-15 was used as a mesoporous template. The surface of CMK-3 was activated using a 2N H2SO4 solution and NH3 gas to prepare CMK-3-H2SO4 and CMK-3-NH3, respectively. The activated samples were characterized by N2 adsorption-desorption, X-ray diffraction, and X-ray photoelectron spectroscopy. The formaldehyde adsorption performance of the mesoporous carbons was in the order of CMK-3-NH3 > CMK-3-H2SO4 > CMK-3. The difference in the adsorption performance was explained by oxygen and nitrogen functional groups formed during the activation process and by the specific surface area and pore structure of mesoporous carbon

    Nanodentistry

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