The Effect of Moderate-Intensity Physical Exercise on Some Serum Inflammation Markers and the Immune System in Rats Fed Intermittent Fasting with a High-Fat Diet

Background and Objectives: This study aimed to investigate the impact of moderate-intensity physical exercise on serum inflammation markers and the immune system in rats that were fed a high-fat diet (HFD) with intermittent fasting. Materials and Methods: A total of 48 Wistar albino male rats were included in the study and divided into eight groups, each consisting of six rats. Group 1 served as the control group (CG), receiving a standard diet. Group 2 followed the standard nutrition program with intermittent fasting (CG + IF). Group 3 underwent exercise with a standard diet (CG + E). Group 4 underwent both a standard diet with intermittent fasting and exercise (CG + IF + E). Group 5 was fed a high-fat diet (HFD). Group 6 received a high-fat diet with intermittent fasting (HFD + IF). Group 7 followed a high-fat diet with exercise (HFD + E). Group 8 underwent both a high-fat diet with intermittent fasting and exercise (HFD + IF + E). The study lasted for 8 weeks. Results: The results of the analysis show that lymphocyte cell levels in groups HFD + IF, HFD + IF, and HFD + IF + E were higher compared to groups CG-HFD (p Conclusions: These findings indicate that moderate exercise and intermittent fasting, particularly in groups fed a high-fat diet, increased anti-inflammatory cytokine levels, and certain immune system cell counts, while decreasing pro-inflammatory cytokine levels

EFFECT OF EXPOSURE TO FLUORINE AND 7, 12-DIMETHYL BENZANTHRACENE ON VASCULAR RESPONSES

In this study, the effect of experimental administration of fluorine and DMBA, alone or in combination, on rats on vascular responses was investigated. After adaptation, the rats were randomly selected and divided into 9 groups, 10 male rats in each group. While sodium fluoride was applied daily in drinking water for 12 weeks to the groups to which fluoride will be applied; on the other hand, DMBA was dissolved in sesame oil and applied to the groups that needed it, once a week for a total of 12 weeks. The groups were determined as C, SO, 1NaF, 15NaF, 30NaF, DMBA, 1NaF+DMBA, 15NaF+DMBA and 30NaF+DMBA. Tensions in the thoracic aorta were provided with phenylephrine. Then, relaxation responses were recorded by giving ACh ((10-8'-7'-6'-5)) and SNP ((10-,-9,-8,-7,)(-6)(,)(-5)) at different cumulative concentrations. In the study, it was determined that fluorine caused the vessels to contract and DMBA to relax. Concurrent exposure to high amounts of fluorine and DMBA was observed to cause vasoconstriction

An Analysis of Neuropeptides at Nasal Contact Points of Patients With Secondary Headache

Conclusions: Although in selected patients significant relief of headache can be obtained by surgery, there is no evidence from this study that SP, NA, and CGRP are responsible for the initiation of headache

Porsuk Çayı’nın Eskişehir üzerindeki etkisinin keşfedilmesi ve incelenmesi üzerine bir araştırma yazısı

Ankara : İhsan Doğramacı Bilkent Üniversitesi İktisadi, İdari ve Sosyal Bilimler Fakültesi, Tarih Bölümü, 2014.This work is a student project of the The Department of History, Faculty of Economics, Administrative and Social Sciences, İhsan Doğramacı Bilkent University.by Özer, Abdürrahim

Effects of Melatonin Dose on Fruit Yield, Quality, and Antioxidants of Strawberry Cultivars Grown in Different Crop Systems

Melatonin acts as a seed germination activator, plant growth regulator, leaf senescence retardant, and, in general, has a multifunctional role as a ‘defence molecule’; furthermore, by interacting with other molecules, such as phytohormones and gaseous molecules, it greatly enhances plant adaptation to different environments. However, there are not enough studies about the use of melatonin on horticultural crops, and even fewer studies have outlined the differences related to this phytohormone use between protected environment and in open field. The two latter systems have different growing conditions that could lead to diversified application doses. As the choice of melatonin dose depends on all crop system components, the present research aimed to assess the effects of three melatonin concentrations (1 ppm, 5 ppm and 10 ppm) plus an untreated control, on yield, quality, and antioxidants of four strawberry cultivars (i.e., Kabarla, Fortuna, Sweet Ann, Festival) grown either in greenhouse or in open field. Research was conducted to assess the yield parameters were better affected by greenhouse than open field, and mean fruit weight was the highest in cultivar Sweet Ann. In open field 10 ppm showed the highest values of fruit number and yield, but in greenhouse did not differ from 5 ppm which led to the highest fruit number. At all melatonin doses, cultivar Kabarla demonstrated the highest yield, compared to the other cultivars, with the maximum value of about 46 t·ha−1. Plant dry weight was 90% higher under greenhouse than in open field conditions, and 52% or 132% higher with cultivar Kabarla in comparison with Fortuna and Sweet Ann, respectively. The melatonin dose of 10 p.p.m showed 56% higher plant dry weight in comparison to the untreated control. Fortuna showed higher values of fruit dry matter, soluble solids, and glucose than Sweet Ann. The fruit dry matter was 7% lower at 10 ppm melatonin than in the untreated control. Fructose was higher under 1 ppm melatonin with 245 mg·g−1 d.w. compared to the untreated control with 220 mg·g−1 d.w. in Festival, whereas in Fortuna was the highest in the control fruits, the latter also showing the highest titratable acidity in Fortuna and Sweet Ann. The highest phenolics content was recorded under 10 ppm melatonin in open field, and with 5 ppm in greenhouse; the phenolics content was the highest under 1 ppm melatonin dose in Kabarla and 5 ppm in Fortuna. Under the protected environment 5 and 10 p.p.m. melatonin elicited the highest accumulation of ascorbic acid; 10 ppm were more effective in Fortuna and Sweet Ann, and 5 ppm in Festival. The most enhanced antioxidant activity was recorded under 5 p.p.m. melatonin dose in Fortuna and Festival. The present study confirms that the dose of melatonin to apply to strawberry crop closely relates both to cultivar and crop system