805 research outputs found

    The emperor\u27s new clothes: how the new atheists are reminding the humanities of their place and purpose in society.

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    This dissertation will examine the social and intellectual impact of the so-called ā€œNew Atheismā€ as evidenced by the writings and public careers of its four principal protagonists: evolutionary biologist Richard Dawkins, philosopher Daniel Dennett, journalist Christopher Hitchens, and neuroscientist Sam Harris. I will argue that the New Atheists together provide an account of reality philosophically superior to that of theism, including those superficially sophisticated variations espoused in the writings of scholars William Lane Craig, John Lennox, Allister McGrath, Alvin Plantinga, etc. Yet, even if this were not so, I would still contend that the accessible, informative, and provocative style of the New Atheistsā€™ prose nevertheless epitomizes precisely what academic writing could and should be. Their commitment to the Enlightenment principles of philosophical objectivity, reason, and the successes of the scientific method stands in stark contrast not only to the more malleable methodology of their religious opponents, but also to the prevailing (and ideologically-conflicting) traditions of deconstructive postmodernism and post-structuralism (as exemplified in the works of Jean Baudrillard, Gilles Deleuze, Jacques Derrida, Jacques Lacan, and others) which have greatly influenced humanitiesā€™ scholarship in recent decades. Therefore, while I very much intend to defend the substance of the New Atheistsā€™ arguments against the various objections of their philosophical, religious, and scientific critics, I simultaneously mean to defend their stylistic choices as well (not only against their critics but also as compared to the obscurant, equivocal, and highly subjective style so often employed by postmodernists). It is my fervent hope that even those who should ultimately disagree with either the New Atheistsā€™ assertions or my defense of them will still be able to see the value of their (and hopefully my) clear, concise brand of communication. For theirs is a style no longer widely employed within the confines of the academy. That said, I believe that the humanities disciplines of history, literary theory, cultural studies, and philosophy would greatly benefit, were they to adopt (or perhaps re-embrace) the communicative model and underlying realist epistemology of the New Atheists

    Mice expressing HLA-DQ6Ī±8Ī² transgenes develop polychondritis spontaneously

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    Relapsing polychondritis (RP) is a human autoimmune disease of unknown etiology in which cartilaginous sites are destroyed by cyclic inflammatory episodes beginning, most commonly, during the fourth or fifth decade of life. We have previously described collagen-induced polychondritis that closely mirrors RP occurring in young (6ā€“8 weeks old) HLA-DQ6Ī±Ī²8Ī±Ī² transgenic AĪ²0 mice, following immunization with heterologous type II collagen (CII). We present evidence here that transgenic strains expressing the DQ6Ī±8Ī² transgene develop spontaneous polychondritis (SP) at the mouse equivalent of human middle age (4.5ā€“6 months and 40ā€“50 years old, respectively) and display polyarthritis, auricular chondritis and nasal chondritis ā€“ three of the most common sites affected in RP. Auricular chondritis in SP, like RP but unlike CII-induced polychondritis, exhibited a relapsing/remitting phenotype, requiring several inflammatory cycles before the cartilage is destroyed. Elevated serum levels of total IgG corresponded with the onset of disease in SP, as in RP and CII-induced polychondritis. No CII-specific immune response was detected in SP, however ā€“ more closely mirroring RP, in which as few as 30% of RP patients have been reported to have CII-specific IgG. CII-induced polychondritis displays a strong CII-specific immune response. SP also demonstrated a strong female preponderance, as some workers have reported in RP but has not observed in CII-induced polychondritis. These characteristics of SP allow for the examination of the immunopathogenesis of polychondritis in the absence of an overwhelming CII-specific immune response and the strong adjuvant-induced immunostimulatory influence in CII-induced polychondritis. This spontaneous model of polychondritis provides a new and unique tool to investigate both the initiatory events as well as the immunopathogenic mechanisms occurring at cartilaginous sites during the cyclic inflammatory assaults of polychondritis

    Parsing brain activity with fMRI and mixed designs: what kind of a state is neuroimaging in?

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    Neuroimaging is often pilloried for providing little more than pretty pictures that simply show where activity occurs in the brain. Strong critics (notably Uttal) have even argued that neuroimaging is nothing more than a modern day version of phrenology: destined to fail, and fundamentally uninformative. Here, I make the opposite case, arguing that neuroimaging is in a vibrant and healthy state of development. As recent investigations of memory illustrate, when used well, neuroimaging goes beyond asking ā€˜whereā€™ activity is occurring, to ask questions concerned more with ā€˜whatā€™ functional role the activity reflects

    HPV Vaccination Knowledge, Attitudes, and Uptake in College Nursing Students

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    Background: The human papillomavirus (HPV) is a preventable, sexually transmitted infection. The vaccines for HPV are safe and effective, but previous research demonstrated that nursing students have low knowledge levels and vaccine uptake. Low knowledge and attitude levels in nurses and nurse practitioners can influence parental and patient decision making for HPV vaccination. Purpose: The purpose of this scholarly project was to evaluate HPV knowledge and attitudes and their association with vaccination uptake in college nursing students. There is limited research in the United States on HPV knowledge, attitudes, and uptake of the vaccine among nursing students. Methods: This project was a replication study utilizing an anonymous, cross-sectional, online survey methodology to measure the HPV knowledge, attitudes, and uptake of the vaccine in nursing students. The survey was given to a convenience sample of undergraduate and graduate nursing students (n = 447) at a private, liberal arts university. Results: Nursing students had high knowledge and attitude scores. While there were no significant differences between knowledge between genders (p = .59), there were differences in knowledge between undergraduate and graduate students (p \u3c .001). There were no differences in attitude between genders and student classification. Knowledge was not associated with uptake (p = .63), but there was an association between attitudes and uptake (p Conclusion:This study supported that nursing students have high knowledge and attitude levels towards HPV and HPV vaccination, which may lead to improved vaccination uptake in the future

    Cognitive-Behavioral Treatment of Social Anxiety Disorder and Comorbid Paranoid Schizophrenia

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    We report on the cognitive-behavioral treatment (CBT) of a patient with comorbid social anxiety disorder (SAD), schizophrenia, and major depressive disorder, complicated by alcohol abuse. Symptoms included auditory hallucinations that commented on the patientā€™s behavior and paranoid thoughts. The paranoid symptoms affected his social interactions as this included the fear that his thoughts may be heard and judged by others. Therapeutic activities raised awareness as to how avoidance interferes with and perpetuates the cycle of depression and psychosis while maintaining symptoms of SAD. Psychoeducation was provided about factors that maintain social anxiety and increase social isolation. New skills were obtained by helping the patient discover alternative ways to view social situations, experimentation, and real-world application to disprove notions about othersā€™ predicted behavior. Treatment led to a great reduction in social anxiety, depression, and suspicious thinking. This case study demonstrates that SAD symptoms in a patient experiencing psychosis can be effectively treated using CBT

    Cognitive-Behavioral Treatment of Social Anxiety Disorder and Comorbid Paranoid Schizophrenia

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    We report on the cognitive-behavioral treatment (CBT) of a patient with comorbid social anxiety disorder (SAD), schizophrenia, and major depressive disorder, complicated by alcohol abuse. Symptoms included auditory hallucinations that commented on the patientā€™s behavior and paranoid thoughts. The paranoid symptoms affected his social interactions as this included the fear that his thoughts may be heard and judged by others. Therapeutic activities raised awareness as to how avoidance interferes with and perpetuates the cycle of depression and psychosis while maintaining symptoms of SAD. Psychoeducation was provided about factors that maintain social anxiety and increase social isolation. New skills were obtained by helping the patient discover alternative ways to view social situations, experimentation, and real-world application to disprove notions about othersā€™ predicted behavior. Treatment led to a great reduction in social anxiety, depression, and suspicious thinking. This case study demonstrates that SAD symptoms in a patient experiencing psychosis can be effectively treated using CBT

    Aquilegia, Vol. 28 No. 4, September-October 2004: Newsletter of the Colorado Native Plant Society

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    https://epublications.regis.edu/aquilegia/1103/thumbnail.jp

    Keratoconus in a patient with Alport syndrome: A case report

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    BACKGROUND Known ocular manifestations of Alport syndrome include features such as anterior lenticonus and fleck retinopathy. Reports of keratoconus in such patients are limited. We report tomographic findings consistent with keratoconus in a patient with Alport syndrome. CASE SUMMARY A 52-year-old female was referred to our ophthalmology clinic with decreased vision and increased tearing. She was diagnosed with stage III Alport syndrome two years prior. Upon examination she was found to have average keratometries of 48 D bilaterally with tomographic evidence of keratoconus. CONCLUSION Although a rare presentation, concurrent Alport syndrome and keratoconus should be considered when reviewing the ocular health of Alport syndrome patients and appropriate management steps should be taken upon the diagnosis

    Culture & biometrics: regional differences in the perception of biometric authentication technologies

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    Previous research has identified user concerns about biometric authentication technology, but most of this research has been conducted in European contexts. There is a lack of research that has investigated attitudes towards biometric technology in other cultures. To address this issue, data from India, South Africa and the United Kingdom were collected and compared. Cross-cultural attitudinal differences were seen, with Indian respondents viewing biometrics most positively while respondents from the United Kingdom were the least likely to have a positive opinion about biometrics. Multiple barriers to the acceptance of biometric technology were identified with data security and health and safety fears having the greatest overall impact on respondentsā€™ attitudes towards biometrics. The results of this investigation are discussed with reference to Hofstedeā€™s cultural dimensions and theories of technology acceptance. It is argued that contextual issues specific to each country provide a better explanation of the results than existing theories based on Hofstedeā€™s model. We conclude that cultural differences have an impact on the way biometric systems will be used and argue that these factors should be taken into account during the design and implementation of biometric systems
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